BR0112486A - Poliproteìna, molécula de ácido nucleico, plasmìdeo, vacina recombinante ou vacina atenuada, composição farmacêutica, e, método para imunizar um indivìduo contra hiv - Google Patents
Poliproteìna, molécula de ácido nucleico, plasmìdeo, vacina recombinante ou vacina atenuada, composição farmacêutica, e, método para imunizar um indivìduo contra hivInfo
- Publication number
- BR0112486A BR0112486A BR0112486-2A BR0112486A BR0112486A BR 0112486 A BR0112486 A BR 0112486A BR 0112486 A BR0112486 A BR 0112486A BR 0112486 A BR0112486 A BR 0112486A
- Authority
- BR
- Brazil
- Prior art keywords
- vaccine
- polyprotein
- immunizing
- plasmid
- nucleic acid
- Prior art date
Links
- 108010076039 Polyproteins Proteins 0.000 title abstract 2
- 108010008038 Synthetic Vaccines Proteins 0.000 title abstract 2
- 229940031567 attenuated vaccine Drugs 0.000 title abstract 2
- 230000003053 immunization Effects 0.000 title abstract 2
- 150000007523 nucleic acids Chemical class 0.000 title abstract 2
- 102000039446 nucleic acids Human genes 0.000 title abstract 2
- 108020004707 nucleic acids Proteins 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000013612 plasmid Substances 0.000 title abstract 2
- 229940124551 recombinant vaccine Drugs 0.000 title abstract 2
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 230000001506 immunosuppresive effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16311—Human Immunodeficiency Virus, HIV concerning HIV regulatory proteins
- C12N2740/16322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/702—Specific hybridization probes for retroviruses
- C12Q1/703—Viruses associated with AIDS
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
"POLIPROTEìNA, MOLéCULA DE áCIDO NUCLEICO, PLASMìDEO, VACINA RECOMBINANTE OU VACINA ATENUADA, COMPOSIçãO FARMACêUTICA, E, MéTODO PARA IMUNIZAR UM INDIVìDUO CONTRA HIV". Vacinas melhoradas e métodos para usar as mesmas são descritas. As composições imunossupressoras para o tratamento de indivíduos que tem doenças autoimunes ou transplantes e métodos para usar as mesmas são descritos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US21819200P | 2000-07-14 | 2000-07-14 | |
PCT/US2001/041357 WO2002006303A2 (en) | 2000-07-14 | 2001-07-12 | Dna vaccines encoding hiv accessory proteins |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0112486A true BR0112486A (pt) | 2004-12-07 |
Family
ID=22814104
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0112486-2A BR0112486A (pt) | 2000-07-14 | 2001-07-12 | Poliproteìna, molécula de ácido nucleico, plasmìdeo, vacina recombinante ou vacina atenuada, composição farmacêutica, e, método para imunizar um indivìduo contra hiv |
Country Status (15)
Country | Link |
---|---|
US (1) | US7488484B2 (pt) |
EP (1) | EP1301637B1 (pt) |
JP (1) | JP2004525604A (pt) |
KR (1) | KR100815888B1 (pt) |
CN (1) | CN1312171C (pt) |
AT (1) | ATE398188T1 (pt) |
AU (2) | AU2001283493B2 (pt) |
BR (1) | BR0112486A (pt) |
CA (1) | CA2415187C (pt) |
DE (1) | DE60134408D1 (pt) |
DK (1) | DK1301637T3 (pt) |
ES (1) | ES2307640T3 (pt) |
IL (2) | IL153576A0 (pt) |
PT (1) | PT1301637E (pt) |
WO (1) | WO2002006303A2 (pt) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UA85373C2 (ru) * | 2002-05-16 | 2009-01-26 | Бавариан Нордик А/С | Слитый протеин регуляторных/аксессорных hіv протеинов |
TW200613554A (en) * | 2004-06-17 | 2006-05-01 | Wyeth Corp | Plasmid having three complete transcriptional units and immunogenic compositions for inducing an immune response to HIV |
EP2049559B1 (en) | 2006-07-28 | 2012-12-19 | The Trustees of the University of Pennsylvania | Improved hpv vaccines |
CN101897964B (zh) * | 2009-04-27 | 2013-04-10 | 中国农业大学 | 一种预防自身免疫疾病的药物 |
US20120135032A1 (en) * | 2009-10-08 | 2012-05-31 | Bavarian Nordic A/S | Generation of a broad t-cell response in humans against hiv |
WO2015106003A1 (en) | 2014-01-08 | 2015-07-16 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Ras pathways as markers of protection against hiv and methods to improve vaccine efficacy |
WO2024144267A1 (ko) * | 2022-12-27 | 2024-07-04 | (주)한국바이오셀프 | Hiv-1 mrna를 포함하는 백신 조성물 |
Family Cites Families (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5077044A (en) * | 1980-05-19 | 1991-12-31 | The Board Of Trustees Of The Leland Stanford Jr. University | Novel non-reverting shigella live vaccines |
US4873191A (en) * | 1981-06-12 | 1989-10-10 | Ohio University | Genetic transformation of zygotes |
US5110587A (en) * | 1981-12-24 | 1992-05-05 | Health Research, Incorporated | Immunogenic composition comprising synthetically modified vaccinia virus |
US5174993A (en) * | 1981-12-24 | 1992-12-29 | Health Research Inc. | Recombinant avipox virus and immunological use thereof |
US5338683A (en) * | 1981-12-24 | 1994-08-16 | Health Research Incorporated | Vaccinia virus containing DNA sequences encoding herpesvirus glycoproteins |
US4722848A (en) * | 1982-12-08 | 1988-02-02 | Health Research, Incorporated | Method for immunizing animals with synthetically modified vaccinia virus |
US4736866B1 (en) * | 1984-06-22 | 1988-04-12 | Transgenic non-human mammals | |
JPS61170732A (ja) * | 1985-01-25 | 1986-08-01 | Fuji Photo Film Co Ltd | ハロゲン化銀写真感光材料 |
GB8508845D0 (en) * | 1985-04-04 | 1985-05-09 | Hoffmann La Roche | Vaccinia dna |
US5223424A (en) * | 1985-09-06 | 1993-06-29 | Prutech Research And Development | Attenuated herpesviruses and herpesviruses which include foreign DNA encoding an amino acid sequence |
US5310668A (en) * | 1986-06-20 | 1994-05-10 | Merck & Co., Inc. | Varicella-zoster virus as a live recombinant vaccine |
US5242829A (en) * | 1986-09-23 | 1993-09-07 | Therion Biologics Corporation | Recombinant pseudorabies virus |
IL86583A0 (en) * | 1987-06-04 | 1988-11-15 | Molecular Eng Ass | Vaccine containing a derivative of a microbe and method for the production thereof |
US5294441A (en) * | 1987-06-04 | 1994-03-15 | Washington University | Avirulent microbes and uses therefor: salmonella typhi |
US5387744A (en) * | 1987-06-04 | 1995-02-07 | Washington University | Avirulent microbes and uses therefor: Salmonella typhi |
US5112749A (en) * | 1987-10-02 | 1992-05-12 | Praxis Biologics, Inc. | Vaccines for the malaria circumsporozoite protein |
US5225336A (en) * | 1989-03-08 | 1993-07-06 | Health Research Incorporated | Recombinant poxvirus host range selection system |
CH682669A5 (fr) * | 1989-03-08 | 1993-10-29 | Health Research Inc | Virus recombinant modifié pour exprimer un produit de gènes chez un hôte, procédés et vaccin correspondants. |
AU645489B2 (en) * | 1989-03-31 | 1994-01-20 | Washington University | Vaccines containing avirulent phoP-type microorganisms |
ES2070997T3 (es) * | 1989-12-04 | 1995-06-16 | Akzo Nobel Nv | Virus de herpes recombinante de pavos y vacunas vector vivas derivadas de los mismos. |
US5294548A (en) * | 1990-04-02 | 1994-03-15 | American Biogenetic Sciences, Inc | Recombianant Hepatitis a virus |
US5462734A (en) * | 1990-11-02 | 1995-10-31 | Wisconsin Alumni Research Foundation | Bovine herpesvirus vaccine and method of using same |
US5240703A (en) * | 1991-03-01 | 1993-08-31 | Syntro Corporation | Attenuated, genetically-engineered pseudorabies virus s-prv-155 and uses thereof |
US5593972A (en) * | 1993-01-26 | 1997-01-14 | The Wistar Institute | Genetic immunization |
US5482701A (en) * | 1993-05-03 | 1996-01-09 | Church & Dwight Co., Inc. | Microporous alkali metal bicarbonate |
US5739118A (en) * | 1994-04-01 | 1998-04-14 | Apollon, Inc. | Compositions and methods for delivery of genetic material |
US5861161A (en) * | 1994-09-07 | 1999-01-19 | Universite De Montreal | Chimeric proteins comprising a Vpr/Vpx virion incorporation domain for targeting into HIV-1 or HIV-2 virions |
US5837533A (en) * | 1994-09-28 | 1998-11-17 | American Home Products Corporation | Complexes comprising a nucleic acid bound to a cationic polyamine having an endosome disruption agent |
JP2967094B2 (ja) * | 1995-11-02 | 1999-10-25 | 工業技術院長 | 窒化アルミニウム焼結体、及び窒化アルミニウム粉末の製造方法 |
CA2792479A1 (en) | 1998-02-27 | 1999-09-02 | The Trustees Of The University Of Pennsylvania | Vaccines, immunotherapeutics and methods for using the same |
US7935805B1 (en) * | 1998-12-31 | 2011-05-03 | Novartis Vaccines & Diagnostics, Inc | Polynucleotides encoding antigenic HIV Type C polypeptides, polypeptides and uses thereof |
-
2001
- 2001-07-12 AU AU2001283493A patent/AU2001283493B2/en not_active Ceased
- 2001-07-12 ES ES01962300T patent/ES2307640T3/es not_active Expired - Lifetime
- 2001-07-12 DK DK01962300T patent/DK1301637T3/da active
- 2001-07-12 CN CNB018127762A patent/CN1312171C/zh not_active Expired - Fee Related
- 2001-07-12 PT PT01962300T patent/PT1301637E/pt unknown
- 2001-07-12 BR BR0112486-2A patent/BR0112486A/pt not_active IP Right Cessation
- 2001-07-12 AU AU8349301A patent/AU8349301A/xx active Pending
- 2001-07-12 CA CA2415187A patent/CA2415187C/en not_active Expired - Fee Related
- 2001-07-12 US US10/312,197 patent/US7488484B2/en not_active Expired - Lifetime
- 2001-07-12 EP EP01962300A patent/EP1301637B1/en not_active Expired - Lifetime
- 2001-07-12 IL IL15357601A patent/IL153576A0/xx unknown
- 2001-07-12 JP JP2002512204A patent/JP2004525604A/ja active Pending
- 2001-07-12 AT AT01962300T patent/ATE398188T1/de active
- 2001-07-12 KR KR1020037000154A patent/KR100815888B1/ko not_active IP Right Cessation
- 2001-07-12 WO PCT/US2001/041357 patent/WO2002006303A2/en active Application Filing
- 2001-07-12 DE DE60134408T patent/DE60134408D1/de not_active Expired - Lifetime
-
2002
- 2002-12-22 IL IL153576A patent/IL153576A/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
KR20030016374A (ko) | 2003-02-26 |
ATE398188T1 (de) | 2008-07-15 |
JP2004525604A (ja) | 2004-08-26 |
EP1301637A2 (en) | 2003-04-16 |
IL153576A0 (en) | 2003-07-06 |
ES2307640T3 (es) | 2008-12-01 |
DE60134408D1 (de) | 2008-07-24 |
EP1301637A4 (en) | 2005-06-01 |
PT1301637E (pt) | 2008-09-18 |
CN1636013A (zh) | 2005-07-06 |
US7488484B2 (en) | 2009-02-10 |
AU8349301A (en) | 2002-01-30 |
US20040106100A1 (en) | 2004-06-03 |
KR100815888B1 (ko) | 2008-03-21 |
CA2415187A1 (en) | 2002-01-24 |
IL153576A (en) | 2010-11-30 |
DK1301637T3 (da) | 2008-09-29 |
CN1312171C (zh) | 2007-04-25 |
AU2001283493B2 (en) | 2006-11-30 |
WO2002006303A3 (en) | 2002-08-15 |
EP1301637B1 (en) | 2008-06-11 |
WO2002006303A2 (en) | 2002-01-24 |
CA2415187C (en) | 2013-06-18 |
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Legal Events
Date | Code | Title | Description |
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B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 14A ANUIDADE. |
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B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2314 DE 12-05-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |