ATE493442T1 - Biologische marker zur vorauswahl von patienten für die anti-igf1r-therapie - Google Patents
Biologische marker zur vorauswahl von patienten für die anti-igf1r-therapieInfo
- Publication number
- ATE493442T1 ATE493442T1 AT05852441T AT05852441T ATE493442T1 AT E493442 T1 ATE493442 T1 AT E493442T1 AT 05852441 T AT05852441 T AT 05852441T AT 05852441 T AT05852441 T AT 05852441T AT E493442 T1 ATE493442 T1 AT E493442T1
- Authority
- AT
- Austria
- Prior art keywords
- patients
- selection
- igf1r
- biological markers
- present
- Prior art date
Links
- 239000000090 biomarker Substances 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 238000000034 method Methods 0.000 abstract 3
- 101001034652 Homo sapiens Insulin-like growth factor 1 receptor Proteins 0.000 abstract 2
- 102100039688 Insulin-like growth factor 1 receptor Human genes 0.000 abstract 2
- 230000002401 inhibitory effect Effects 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 230000000692 anti-sense effect Effects 0.000 abstract 1
- 238000011319 anticancer therapy Methods 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000003384 small molecules Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Urology & Nephrology (AREA)
- Genetics & Genomics (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63315604P | 2004-12-03 | 2004-12-03 | |
| PCT/US2005/043184 WO2006060419A2 (en) | 2004-12-03 | 2005-11-30 | Biomarkers for pre-selection of patients for anti-igf1r therapy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE493442T1 true ATE493442T1 (de) | 2011-01-15 |
Family
ID=36190453
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05852441T ATE493442T1 (de) | 2004-12-03 | 2005-11-30 | Biologische marker zur vorauswahl von patienten für die anti-igf1r-therapie |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7811562B2 (OSRAM) |
| EP (3) | EP2283831A3 (OSRAM) |
| JP (3) | JP2008521907A (OSRAM) |
| AT (1) | ATE493442T1 (OSRAM) |
| CA (1) | CA2589885A1 (OSRAM) |
| DE (1) | DE602005025685D1 (OSRAM) |
| ES (1) | ES2356830T3 (OSRAM) |
| MX (1) | MX2007006640A (OSRAM) |
| PT (1) | PT1828249E (OSRAM) |
| TW (1) | TWI376233B (OSRAM) |
| WO (1) | WO2006060419A2 (OSRAM) |
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| US20080193445A1 (en) * | 2002-01-18 | 2008-08-14 | Liliane Goetsch | Novel anti-IGF-IR antibodies and uses thereof |
| EP2316922B1 (en) * | 2002-05-24 | 2013-05-22 | Merck Sharp & Dohme Corp. | Neutralizing human anti-IGFR antibody |
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| CA2524305C (en) | 2003-05-01 | 2015-12-08 | Imclone Systems Incorporated | Fully human antibodies directed against the human insulin-like growth factor-1 receptor |
| AR046639A1 (es) * | 2003-11-21 | 2005-12-14 | Schering Corp | Combinaciones terapeuticas de anticuerpo anti- igfr1 |
| CA2605158A1 (en) | 2005-04-14 | 2006-10-26 | The Trustees Of Boston University | Diagnostic for lung disorders using class prediction |
| EP1879587A2 (en) * | 2005-04-15 | 2008-01-23 | Schering Corporation | Methods and compositions for treating or preventing cancer |
| CN101500597A (zh) | 2005-06-17 | 2009-08-05 | 伊姆克罗尼系统公司 | 治疗转移性骨癌的受体拮抗剂 |
| JP5055284B2 (ja) | 2005-09-20 | 2012-10-24 | オーエスアイ・フアーマシユーテイカルズ・エル・エル・シー | インシュリン様成長因子−1受容体キナーゼ阻害剤に対する抗癌応答を予測する生物学的マーカー |
| KR101353706B1 (ko) | 2006-02-03 | 2014-02-18 | 유니버시티 오브 워싱톤 | 전립선 암 치료용 보강제로서의 ⅰgf-ⅰr 길항제 |
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| AU2008302076B2 (en) * | 2007-09-19 | 2015-06-11 | The Trustees Of Boston University | Identification of novel pathways for drug development for lung disease |
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-
2005
- 2005-11-30 EP EP10185346.3A patent/EP2283831A3/en not_active Withdrawn
- 2005-11-30 CA CA002589885A patent/CA2589885A1/en not_active Abandoned
- 2005-11-30 WO PCT/US2005/043184 patent/WO2006060419A2/en not_active Ceased
- 2005-11-30 JP JP2007544441A patent/JP2008521907A/ja not_active Withdrawn
- 2005-11-30 EP EP05852441A patent/EP1828249B1/en not_active Expired - Lifetime
- 2005-11-30 EP EP10184355.5A patent/EP2281841A3/en not_active Withdrawn
- 2005-11-30 AT AT05852441T patent/ATE493442T1/de not_active IP Right Cessation
- 2005-11-30 US US11/290,687 patent/US7811562B2/en not_active Expired - Fee Related
- 2005-11-30 DE DE602005025685T patent/DE602005025685D1/de not_active Expired - Lifetime
- 2005-11-30 MX MX2007006640A patent/MX2007006640A/es active IP Right Grant
- 2005-11-30 PT PT05852441T patent/PT1828249E/pt unknown
- 2005-11-30 ES ES05852441T patent/ES2356830T3/es not_active Expired - Lifetime
- 2005-12-01 TW TW094142319A patent/TWI376233B/zh active
-
2011
- 2011-05-13 JP JP2011108837A patent/JP2011157397A/ja active Pending
- 2011-12-21 JP JP2011280276A patent/JP2012067124A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US7811562B2 (en) | 2010-10-12 |
| WO2006060419A3 (en) | 2006-08-24 |
| EP2283831A3 (en) | 2013-10-23 |
| DE602005025685D1 (de) | 2011-02-10 |
| EP1828249B1 (en) | 2010-12-29 |
| EP1828249A2 (en) | 2007-09-05 |
| ES2356830T3 (es) | 2011-04-13 |
| EP2281841A3 (en) | 2013-10-23 |
| JP2011157397A (ja) | 2011-08-18 |
| US20060140960A1 (en) | 2006-06-29 |
| MX2007006640A (es) | 2007-06-19 |
| EP2281841A2 (en) | 2011-02-09 |
| JP2012067124A (ja) | 2012-04-05 |
| TWI376233B (en) | 2012-11-11 |
| CA2589885A1 (en) | 2006-06-08 |
| EP2283831A2 (en) | 2011-02-16 |
| TW200626174A (en) | 2006-08-01 |
| WO2006060419A2 (en) | 2006-06-08 |
| JP2008521907A (ja) | 2008-06-26 |
| WO2006060419A9 (en) | 2006-07-20 |
| PT1828249E (pt) | 2011-02-25 |
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