ATE472099T1 - Multiplex-fluoreszenzdetektionsvorrichtung mit entfernbaren optischen modulen - Google Patents
Multiplex-fluoreszenzdetektionsvorrichtung mit entfernbaren optischen modulenInfo
- Publication number
- ATE472099T1 ATE472099T1 AT06748651T AT06748651T ATE472099T1 AT E472099 T1 ATE472099 T1 AT E472099T1 AT 06748651 T AT06748651 T AT 06748651T AT 06748651 T AT06748651 T AT 06748651T AT E472099 T1 ATE472099 T1 AT E472099T1
- Authority
- AT
- Austria
- Prior art keywords
- optical modules
- removable optical
- species
- detection device
- fluorescent light
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
- G01N35/00069—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides whereby the sample substrate is of the bio-disk type, i.e. having the format of an optical disk
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/173—Nucleic acid detection characterized by the use of physical, structural and functional properties staining/intercalating agent, e.g. ethidium bromide
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N2021/6417—Spectrofluorimetric devices
- G01N2021/6419—Excitation at two or more wavelengths
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N2021/6417—Spectrofluorimetric devices
- G01N2021/6421—Measuring at two or more wavelengths
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
- G01N2021/6441—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks with two or more labels
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/02—Mechanical
- G01N2201/024—Modular construction
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US66746105P | 2005-04-01 | 2005-04-01 | |
US11/174,754 US7507575B2 (en) | 2005-04-01 | 2005-07-05 | Multiplex fluorescence detection device having removable optical modules |
PCT/US2006/010787 WO2006107619A1 (en) | 2005-04-01 | 2006-03-24 | Multiplex fluorescence detection device having removable optical modules |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE472099T1 true ATE472099T1 (de) | 2010-07-15 |
Family
ID=36591356
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT06748651T ATE472099T1 (de) | 2005-04-01 | 2006-03-24 | Multiplex-fluoreszenzdetektionsvorrichtung mit entfernbaren optischen modulen |
Country Status (12)
Country | Link |
---|---|
US (2) | US7507575B2 (de) |
EP (2) | EP2207026A1 (de) |
JP (1) | JP5021614B2 (de) |
KR (1) | KR101265362B1 (de) |
AT (1) | ATE472099T1 (de) |
AU (1) | AU2006232922A1 (de) |
BR (1) | BRPI0609544B8 (de) |
CA (1) | CA2602587A1 (de) |
DE (1) | DE602006015043D1 (de) |
ES (1) | ES2347077T3 (de) |
MX (1) | MX2007012159A (de) |
WO (1) | WO2006107619A1 (de) |
Families Citing this family (82)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6692700B2 (en) | 2001-02-14 | 2004-02-17 | Handylab, Inc. | Heat-reduction methods and systems related to microfluidic devices |
US7829025B2 (en) | 2001-03-28 | 2010-11-09 | Venture Lending & Leasing Iv, Inc. | Systems and methods for thermal actuation of microfluidic devices |
US8895311B1 (en) | 2001-03-28 | 2014-11-25 | Handylab, Inc. | Methods and systems for control of general purpose microfluidic devices |
JP4996248B2 (ja) | 2003-07-31 | 2012-08-08 | ハンディーラブ インコーポレイテッド | 粒子含有サンプルの処理 |
US8852862B2 (en) | 2004-05-03 | 2014-10-07 | Handylab, Inc. | Method for processing polynucleotide-containing samples |
US7709249B2 (en) * | 2005-04-01 | 2010-05-04 | 3M Innovative Properties Company | Multiplex fluorescence detection device having fiber bundle coupling multiple optical modules to a common detector |
US7507575B2 (en) | 2005-04-01 | 2009-03-24 | 3M Innovative Properties Company | Multiplex fluorescence detection device having removable optical modules |
US20070009382A1 (en) * | 2005-07-05 | 2007-01-11 | William Bedingham | Heating element for a rotating multiplex fluorescence detection device |
US7527763B2 (en) * | 2005-07-05 | 2009-05-05 | 3M Innovative Properties Company | Valve control system for a rotating multiplex fluorescence detection device |
US7727473B2 (en) | 2005-10-19 | 2010-06-01 | Progentech Limited | Cassette for sample preparation |
US7754148B2 (en) | 2006-12-27 | 2010-07-13 | Progentech Limited | Instrument for cassette for sample preparation |
US10900066B2 (en) | 2006-03-24 | 2021-01-26 | Handylab, Inc. | Microfluidic system for amplifying and detecting polynucleotides in parallel |
US11806718B2 (en) | 2006-03-24 | 2023-11-07 | Handylab, Inc. | Fluorescence detector for microfluidic diagnostic system |
US7998708B2 (en) | 2006-03-24 | 2011-08-16 | Handylab, Inc. | Microfluidic system for amplifying and detecting polynucleotides in parallel |
DK2001990T3 (en) | 2006-03-24 | 2016-10-03 | Handylab Inc | Integrated microfluidic sample processing system and method for its use |
WO2008060604A2 (en) | 2006-11-14 | 2008-05-22 | Handylab, Inc. | Microfluidic system for amplifying and detecting polynucleotides in parallel |
US8765076B2 (en) | 2006-11-14 | 2014-07-01 | Handylab, Inc. | Microfluidic valve and method of making same |
US8182763B2 (en) | 2007-07-13 | 2012-05-22 | Handylab, Inc. | Rack for sample tubes and reagent holders |
US8287820B2 (en) | 2007-07-13 | 2012-10-16 | Handylab, Inc. | Automated pipetting apparatus having a combined liquid pump and pipette head system |
AU2008276211B2 (en) | 2007-07-13 | 2015-01-22 | Handylab, Inc. | Polynucleotide capture materials, and methods of using same |
US9618139B2 (en) | 2007-07-13 | 2017-04-11 | Handylab, Inc. | Integrated heater and magnetic separator |
US8105783B2 (en) | 2007-07-13 | 2012-01-31 | Handylab, Inc. | Microfluidic cartridge |
US9186677B2 (en) | 2007-07-13 | 2015-11-17 | Handylab, Inc. | Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples |
EP2276849B1 (de) * | 2008-04-24 | 2014-12-03 | 3M Innovative Properties Company | Untersuchung von nukleinsäureamplifikationskurven anhand von wavelet-transformation |
USD787087S1 (en) | 2008-07-14 | 2017-05-16 | Handylab, Inc. | Housing |
GB0817991D0 (en) * | 2008-10-02 | 2008-11-05 | Enigma Diagnostics Ltd | Fluorescence based detection methods and apparatus |
JP5655232B2 (ja) * | 2008-12-05 | 2015-01-21 | ビオカルティ ナームローゼ フェノーツハップBiocartis NV | 搬送ヒータを有する熱サイクルシステム |
JP5279481B2 (ja) | 2008-12-25 | 2013-09-04 | 株式会社日立ハイテクノロジーズ | 核酸分析装置 |
EP2391732B1 (de) | 2009-01-30 | 2015-05-27 | Oxford Nanopore Technologies Limited | Verfahren die adaptoren zur nukleinsaure constructen für transmembrane sequenzierung benutzen |
CN102341710B (zh) * | 2009-04-15 | 2015-04-01 | 比奥卡尔齐什股份有限公司 | 用于监视rtPCR反应的光学检测系统 |
EP2277624A3 (de) * | 2009-07-20 | 2013-12-18 | Samsung Electronics Co., Ltd. | Scheibenartige mikrofluidische Vorrichtung und Bluttestgerät, das sie verwendet |
PT3375890T (pt) | 2009-09-10 | 2020-04-23 | Diasorin S P A | Métodos e dispositivos para determinação de uma correcção de diafonia em amplificação de ácido nucleico |
US9127313B2 (en) | 2009-12-01 | 2015-09-08 | Oxford Nanopore Technologies Limited | Biochemical analysis instrument |
EP3150690B1 (de) | 2010-02-23 | 2022-04-06 | Luminex Corporation | Vorrichtung für die manipulation von kartuschen zur isolierung und amplifizierung von nukleinsäuren |
US8729502B1 (en) | 2010-10-28 | 2014-05-20 | The Research Foundation For The State University Of New York | Simultaneous, single-detector fluorescence detection of multiple analytes with frequency-specific lock-in detection |
CN102175612B (zh) * | 2011-01-18 | 2012-12-26 | 河北工业大学 | 一种多路光电检测装置 |
US9096892B1 (en) | 2011-02-04 | 2015-08-04 | K2 Biomicrosystems, LLC | Nucleic acid amplification and monitoring apparatus |
PT3270141T (pt) | 2011-03-08 | 2020-08-28 | Univ Laval | Dispositivo centrípeto fluídico |
CN106190806B (zh) * | 2011-04-15 | 2018-11-06 | 贝克顿·迪金森公司 | 扫描实时微流体热循环仪和用于同步的热循环和扫描光学检测的方法 |
WO2012151473A2 (en) | 2011-05-04 | 2012-11-08 | Luminex Corporation | Apparatus and methods for integrated sample preparation, reaction and detection |
CN105170203B (zh) | 2011-05-18 | 2017-07-18 | 3M创新有限公司 | 检测选定体积的材料在样本处理装置中存在的系统和方法 |
AU2012255144B2 (en) | 2011-05-18 | 2015-01-29 | Diasorin Italia S.P.A. | Systems and methods for volumetric metering on a sample processing device |
WO2012158988A1 (en) | 2011-05-18 | 2012-11-22 | 3M Innovative Properties Company | Systems and methods for valving on a sample processing device |
USD672467S1 (en) | 2011-05-18 | 2012-12-11 | 3M Innovative Properties Company | Rotatable sample processing disk |
IN2014DN00221A (de) | 2011-07-25 | 2015-06-05 | Oxford Nanopore Tech Ltd | |
KR102121853B1 (ko) | 2011-09-30 | 2020-06-12 | 벡톤 디킨슨 앤드 컴퍼니 | 일체화된 시약 스트립 |
USD692162S1 (en) | 2011-09-30 | 2013-10-22 | Becton, Dickinson And Company | Single piece reagent holder |
EP2761027B1 (de) | 2011-09-30 | 2017-10-25 | Life Technologies Corporation | Verfahren und systeme zur visualisierung und auswertung von daten |
CN104040238B (zh) | 2011-11-04 | 2017-06-27 | 汉迪拉布公司 | 多核苷酸样品制备装置 |
AU2013214849B2 (en) | 2012-02-03 | 2016-09-01 | Becton, Dickinson And Company | External files for distribution of molecular diagnostic tests and determination of compatibility between tests |
KR102145677B1 (ko) | 2012-02-03 | 2020-08-18 | 캘리포니아 인스티튜트 오브 테크놀로지 | 다중화된 생화학적 분석에서의 시그널 인코딩 및 디코딩 |
US9193996B2 (en) | 2012-04-03 | 2015-11-24 | Illumina, Inc. | Integrated optoelectronic read head and fluidic cartridge useful for nucleic acid sequencing |
JP5797870B2 (ja) * | 2012-04-23 | 2015-10-21 | シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッドSiemens Healthcare Diagnostics Inc. | 生物学的検定サンプル・アナライザ |
EP2875154B1 (de) | 2012-07-19 | 2017-08-23 | Oxford Nanopore Technologies Limited | SSB-Verfahren zur Charakterisierung einer Nukleinsäure |
US9791372B2 (en) | 2012-08-03 | 2017-10-17 | California Institute Of Technology | Multiplexing and quantification in PCR with reduced hardware and requirements |
CA2879638A1 (en) | 2012-08-10 | 2014-02-13 | Streck, Inc. | Real-time optical system for polymerase chain reaction |
CN103364378B (zh) * | 2013-03-05 | 2016-04-20 | 江苏天瑞仪器股份有限公司 | 一种用于原子荧光光谱仪的多功能联合进样系统 |
GB201314695D0 (en) | 2013-08-16 | 2013-10-02 | Oxford Nanopore Tech Ltd | Method |
WO2014135838A1 (en) | 2013-03-08 | 2014-09-12 | Oxford Nanopore Technologies Limited | Enzyme stalling method |
US8858886B1 (en) | 2013-05-08 | 2014-10-14 | Agilent Technologies, Inc. | Scanning system with interchangeable optical cartridges for fluorescence measurements |
EP3014251A1 (de) * | 2013-06-28 | 2016-05-04 | Streck Inc. | Vorrichtungen für echtzeit-polymerasekettenreaktionen |
DE102013012609A1 (de) * | 2013-07-26 | 2015-01-29 | Carl Zeiss Microscopy Gmbh | Optoelektronischer Detektor, insbesondere für hochauflösende Lichtrastermikroskope |
FI3030645T3 (fi) * | 2013-08-08 | 2023-02-10 | Fluidijärjestelmä reagenssien toimittamiseen virtauskennoon | |
GB201403096D0 (en) | 2014-02-21 | 2014-04-09 | Oxford Nanopore Tech Ltd | Sample preparation method |
GB201418159D0 (en) | 2014-10-14 | 2014-11-26 | Oxford Nanopore Tech Ltd | Method |
WO2016160996A1 (en) * | 2015-03-30 | 2016-10-06 | DeNovix, Inc. | Apparatus and method for measuring fluorescence of a sample |
US10209242B2 (en) | 2015-05-21 | 2019-02-19 | Emit Imaging, Inc. | Fluorescence histo-tomography (FHT) systems and methods |
WO2017040671A1 (en) * | 2015-08-31 | 2017-03-09 | Invicro, Llc | Fluorescence histo-tomography (fht) systems and methods |
USD799715S1 (en) | 2015-10-23 | 2017-10-10 | Gene POC, Inc. | Fluidic centripetal device |
US10272510B2 (en) * | 2016-01-14 | 2019-04-30 | United Technologies Corporation | Electrical discharge machining apparatus |
JP6687834B2 (ja) * | 2016-02-03 | 2020-04-28 | 株式会社Jvcケンウッド | 分析装置及び分析方法 |
KR101904506B1 (ko) * | 2016-05-25 | 2018-10-05 | (주)옵토레인 | 피씨알모듈 |
KR101972579B1 (ko) * | 2016-05-25 | 2019-08-23 | (주)옵토레인 | 피씨알모듈 및 이를 이용한 검사방법 |
GB201609220D0 (en) | 2016-05-25 | 2016-07-06 | Oxford Nanopore Tech Ltd | Method |
CN106198480B (zh) * | 2016-08-30 | 2018-09-14 | 广州蓝勃生物科技有限公司 | 一种自动干式荧光检测仪 |
CN106290286A (zh) * | 2016-09-20 | 2017-01-04 | 广东顺德工业设计研究院(广东顺德创新设计研究院) | 时间分辨荧光分析系统及检测装置 |
GB201704771D0 (en) * | 2017-01-05 | 2017-05-10 | Illumina Inc | Modular optical analytic systems and methods |
US10431441B2 (en) * | 2018-01-31 | 2019-10-01 | Palodex Group Oy | Reducing calibration of components in an imaging plate scanner |
GB201807793D0 (en) | 2018-05-14 | 2018-06-27 | Oxford Nanopore Tech Ltd | Method |
CN110656046A (zh) * | 2019-11-01 | 2020-01-07 | 中国人民解放军军事科学院军事医学研究院 | 一种探测装置及pcr仪 |
CN112823890A (zh) * | 2020-07-30 | 2021-05-21 | 北京金诺美生物技术有限公司 | 一种实时荧光定量pcr仪 |
CN112798773A (zh) * | 2020-12-27 | 2021-05-14 | 北京工业大学 | 一种基于stm32单片机的高分辨率酶标仪电控系统 |
Family Cites Families (84)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3918793A (en) * | 1970-05-02 | 1975-11-11 | Leitz Ernst Gmbh | Fluorescence illuminator for incident light microscope |
DE2055944A1 (de) | 1970-11-13 | 1972-05-18 | Leitz Ernst Gmbh | Fluoreszenzauflichtilluminator |
DE2420545C3 (de) * | 1974-04-27 | 1979-01-25 | H. Maihak Ag, 2000 Hamburg | Infrarotstrahleranordnung |
JPS55156840A (en) * | 1979-05-25 | 1980-12-06 | Olympus Optical Co Ltd | Specimen detector |
JPS6120839A (ja) | 1984-07-10 | 1986-01-29 | Fuji Photo Film Co Ltd | バクテリアカウンタ |
US4726676A (en) * | 1986-02-06 | 1988-02-23 | General Signal Corporation | Optical signal power measurement method and apparatus |
US4927766A (en) * | 1986-05-27 | 1990-05-22 | The Boc Group, Inc. | Gas constituent measurement and recording |
US4909990A (en) * | 1987-09-02 | 1990-03-20 | Myron J. Block | Immunoassay apparatus |
GB8919700D0 (en) | 1989-08-31 | 1989-10-11 | Electricity Council | Infra-red radiation emission arrangement |
US7273749B1 (en) * | 1990-06-04 | 2007-09-25 | University Of Utah Research Foundation | Container for carrying out and monitoring biological processes |
US5296958A (en) * | 1992-05-29 | 1994-03-22 | Eastman Kodak Company | Multiple wavelength laser beam scanning system |
AU668951B2 (en) * | 1992-07-17 | 1996-05-23 | Becton Dickinson & Company | Method and apparatus for detecting bacterial growth by spectrophotometric sampling of a fiber-optic array |
JPH0634546A (ja) * | 1992-07-17 | 1994-02-08 | Tosoh Corp | 蛍光検出器 |
US5414600A (en) * | 1993-07-30 | 1995-05-09 | Cogent Light Technologies, Inc. | Condensing and collecting optical system using an ellipsoidal reflector |
JP2909216B2 (ja) * | 1994-04-29 | 1999-06-23 | パーキン‐エルマー コーポレイション | 核酸増幅生成物のリアルタイム検出装置 |
US5766889A (en) * | 1994-06-08 | 1998-06-16 | The Perkin-Elmer Corporation | Method for determining the characteristics of the concentration growth of target nucleic acid molecules in polymerase chain reaction sample |
US6327031B1 (en) * | 1998-09-18 | 2001-12-04 | Burstein Technologies, Inc. | Apparatus and semi-reflective optical system for carrying out analysis of samples |
GB9418981D0 (en) * | 1994-09-21 | 1994-11-09 | Univ Glasgow | Apparatus and method for carrying out analysis of samples |
US5585069A (en) * | 1994-11-10 | 1996-12-17 | David Sarnoff Research Center, Inc. | Partitioned microelectronic and fluidic device array for clinical diagnostics and chemical synthesis |
US5639668A (en) * | 1995-09-14 | 1997-06-17 | Boehringer Mannheim Corporation | Optical apparatus for performing an immunoassay |
US6342349B1 (en) * | 1996-07-08 | 2002-01-29 | Burstein Technologies, Inc. | Optical disk-based assay devices and methods |
US5751874A (en) * | 1996-09-13 | 1998-05-12 | Nuvisions International, Inc. | Coupling device for linking optical fiber connectors |
DE19707226A1 (de) * | 1997-02-24 | 1998-08-27 | Bodenseewerk Perkin Elmer Co | Lichtabtastvorrichtung |
TR199902440T2 (xx) | 1997-02-28 | 2000-02-21 | Burstein Laboratories, Inc. | Disk �zerinde laboratuar. |
KR100345817B1 (ko) * | 1997-03-25 | 2002-07-24 | 산요 덴키 가부시키가이샤 | 정보 재생 장치와 정보 기록 장치 및 기준 마크 검출 회로 |
US6563113B1 (en) * | 1997-09-05 | 2003-05-13 | Leica Microsystems (Schweiz) Ag | Microscope, especially a fluorescence microscope, particularly a stereo fluorescence microscope |
US6597450B1 (en) * | 1997-09-15 | 2003-07-22 | Becton, Dickinson And Company | Automated Optical Reader for Nucleic Acid Assays |
US6561428B2 (en) * | 1997-10-17 | 2003-05-13 | Hand Held Products, Inc. | Imaging device having indicia-controlled image parsing mode |
US5994150A (en) * | 1997-11-19 | 1999-11-30 | Imation Corp. | Optical assaying method and system having rotatable sensor disk with multiple sensing regions |
WO1999037204A1 (en) * | 1998-01-26 | 1999-07-29 | Massachusetts Institute Of Technology | Fluorescence imaging endoscope |
US6210882B1 (en) * | 1998-01-29 | 2001-04-03 | Mayo Foundation For Medical Education And Reseach | Rapid thermocycling for sample analysis |
US6014618A (en) * | 1998-08-06 | 2000-01-11 | Dsp Software Engineering, Inc. | LPAS speech coder using vector quantized, multi-codebook, multi-tap pitch predictor and optimized ternary source excitation codebook derivation |
US6161946A (en) * | 1998-11-09 | 2000-12-19 | Bishop; Christopher B. | Light reflector |
EP1141409B2 (de) * | 1998-12-14 | 2009-05-27 | Pacific Biosciences of California, Inc. | Kit und methode zur nukleinsäuresequenzierung einzelner moleküle durch polymerase synthese |
JP3597729B2 (ja) * | 1999-05-11 | 2004-12-08 | 日立ソフトウエアエンジニアリング株式会社 | 蛍光測光方法及び蛍光測光装置 |
US7410793B2 (en) * | 1999-05-17 | 2008-08-12 | Applera Corporation | Optical instrument including excitation source |
GB2351556B (en) | 1999-06-26 | 2004-06-30 | Cambridge Imaging Ltd | Improved assay analysis |
US7088650B1 (en) * | 1999-08-23 | 2006-08-08 | Worthington Mark O | Methods and apparatus for optical disc data acquisition using physical synchronization markers |
CN1311436A (zh) * | 2000-03-01 | 2001-09-05 | 上海和泰光电科技有限公司 | 旋转平台上的生物芯片荧光图象的读取 |
JP2001281587A (ja) * | 2000-03-31 | 2001-10-10 | Fuji Photo Optical Co Ltd | 光走査装置用光源部の保持構造 |
US6795189B2 (en) * | 2000-06-15 | 2004-09-21 | Packard Instrument Company | Universal microplate analyzer |
US6627159B1 (en) * | 2000-06-28 | 2003-09-30 | 3M Innovative Properties Company | Centrifugal filling of sample processing devices |
US6734401B2 (en) * | 2000-06-28 | 2004-05-11 | 3M Innovative Properties Company | Enhanced sample processing devices, systems and methods |
US6563581B1 (en) * | 2000-07-14 | 2003-05-13 | Applera Corporation | Scanning system and method for scanning a plurality of samples |
FR2812306B1 (fr) * | 2000-07-28 | 2005-01-14 | Gabriel Festoc | Systeme d'amplification en chaine par polymerse de sequences nucleiques cibles |
US6545758B1 (en) * | 2000-08-17 | 2003-04-08 | Perry Sandstrom | Microarray detector and synthesizer |
US6452879B1 (en) * | 2000-09-29 | 2002-09-17 | Fujitsu Limited | Optical storage apparatus |
WO2002029850A2 (en) * | 2000-10-04 | 2002-04-11 | Cogent Light Technologies, Inc. | Temperature control for arc lamps |
SE0004296D0 (sv) * | 2000-11-23 | 2000-11-23 | Gyros Ab | Device and method for the controlled heating in micro channel systems |
US20020172980A1 (en) * | 2000-11-27 | 2002-11-21 | Phan Brigitte Chau | Methods for decreasing non-specific binding of beads in dual bead assays including related optical biodiscs and disc drive systems |
AU2002219979A1 (en) * | 2000-12-01 | 2002-06-11 | Burstein Technologies, Inc. | Apparatus and methods for separating components of particulate suspension |
US20030077598A1 (en) * | 2001-01-04 | 2003-04-24 | Phan Brigitte Chau | Dual bead assays including covalent linkages for improved specificity and related optical analysis discs |
WO2002073605A2 (en) | 2001-03-14 | 2002-09-19 | Burstein Technologies, Inc. | Dual bead assays using cleavable spacers and/or ligation to improve specificity and sensitivity including related methods and apparatus |
US20030054563A1 (en) * | 2001-09-17 | 2003-03-20 | Gyros Ab | Detector arrangement for microfluidic devices |
US6597832B2 (en) * | 2001-12-07 | 2003-07-22 | Yu-Feng Cheng | Optical fiber selector |
US6889468B2 (en) | 2001-12-28 | 2005-05-10 | 3M Innovative Properties Company | Modular systems and methods for using sample processing devices |
WO2003060668A2 (en) * | 2002-01-14 | 2003-07-24 | Burstein Technologies, Inc. | Method and apparatus for visualizing data |
US20050023765A1 (en) * | 2002-01-31 | 2005-02-03 | Coombs James Howard | Bio-safety features for optical analysis disc and disc system including same |
US6767155B2 (en) * | 2002-04-05 | 2004-07-27 | Eastman Kodak Company | High stability latch mechanism |
WO2003087779A1 (en) * | 2002-04-08 | 2003-10-23 | Gyros Ab | Homing process |
US6833536B2 (en) * | 2002-05-22 | 2004-12-21 | Applera Corporation | Non-contact radiant heating and temperature sensing device for a chemical reaction chamber |
EP2463644B1 (de) | 2002-05-17 | 2013-10-09 | Life Technologies Corporation | Optisches Instrument mit Anregungsquelle |
WO2003098278A2 (en) | 2002-05-17 | 2003-11-27 | Applera Corporation | Apparatus and method for differentiating multiple fluorescence signals by excitation wavelength |
US20030219754A1 (en) * | 2002-05-23 | 2003-11-27 | Oleksy Jerome E. | Fluorescence polarization detection of nucleic acids |
AUPS267802A0 (en) | 2002-05-30 | 2002-06-20 | Bio-Molecular Holdings Pty Limited | Improved dna amplification apparatus and method |
JP4193421B2 (ja) * | 2002-06-06 | 2008-12-10 | ソニー株式会社 | バイオアッセイ装置及びその製造方法、並びにバイオアッセイ方法 |
US7452507B2 (en) * | 2002-08-02 | 2008-11-18 | Sandia Corporation | Portable apparatus for separating sample and detecting target analytes |
AU2003293399A1 (en) * | 2002-12-04 | 2004-06-23 | Spinx, Inc. | Devices and methods for programmable microscale manipulation of fluids |
US20050014249A1 (en) * | 2003-02-21 | 2005-01-20 | Norbert Staimer | Chromatographic analysis on optical bio-discs and methods relating thereto |
US20050032089A1 (en) | 2003-03-05 | 2005-02-10 | Phan Brigitte Chau | Sample preparation for colorimetric and fluorescent assays as implemented on optical analysis discs |
EP2284278A1 (de) | 2003-04-04 | 2011-02-16 | Roche Diagnostics GmbH | Verbessertes System für Mehrfarben-Echtzeit-PCR |
US7148043B2 (en) * | 2003-05-08 | 2006-12-12 | Bio-Rad Laboratories, Inc. | Systems and methods for fluorescence detection with a movable detection module |
US7238269B2 (en) * | 2003-07-01 | 2007-07-03 | 3M Innovative Properties Company | Sample processing device with unvented channel |
US6879032B2 (en) * | 2003-07-18 | 2005-04-12 | Agilent Technologies, Inc. | Folded flex circuit interconnect having a grid array interface |
US7317415B2 (en) | 2003-08-08 | 2008-01-08 | Affymetrix, Inc. | System, method, and product for scanning of biological materials employing dual analog integrators |
US20050074784A1 (en) * | 2003-10-07 | 2005-04-07 | Tuan Vo-Dinh | Integrated biochip with continuous sampling and processing (CSP) system |
US20050130177A1 (en) * | 2003-12-12 | 2005-06-16 | 3M Innovative Properties Company | Variable valve apparatus and methods |
US7322254B2 (en) * | 2003-12-12 | 2008-01-29 | 3M Innovative Properties Company | Variable valve apparatus and methods |
US7295316B2 (en) * | 2004-01-14 | 2007-11-13 | Applera Corporation | Fluorescent detector with automatic changing filters |
US7709249B2 (en) * | 2005-04-01 | 2010-05-04 | 3M Innovative Properties Company | Multiplex fluorescence detection device having fiber bundle coupling multiple optical modules to a common detector |
US7507575B2 (en) | 2005-04-01 | 2009-03-24 | 3M Innovative Properties Company | Multiplex fluorescence detection device having removable optical modules |
US7754474B2 (en) * | 2005-07-05 | 2010-07-13 | 3M Innovative Properties Company | Sample processing device compression systems and methods |
US20070009382A1 (en) * | 2005-07-05 | 2007-01-11 | William Bedingham | Heating element for a rotating multiplex fluorescence detection device |
US7527763B2 (en) * | 2005-07-05 | 2009-05-05 | 3M Innovative Properties Company | Valve control system for a rotating multiplex fluorescence detection device |
-
2005
- 2005-07-05 US US11/174,754 patent/US7507575B2/en active Active
-
2006
- 2006-03-24 EP EP10161462A patent/EP2207026A1/de not_active Withdrawn
- 2006-03-24 AU AU2006232922A patent/AU2006232922A1/en not_active Abandoned
- 2006-03-24 EP EP06748651A patent/EP1872112B1/de active Active
- 2006-03-24 WO PCT/US2006/010787 patent/WO2006107619A1/en active Application Filing
- 2006-03-24 ES ES06748651T patent/ES2347077T3/es active Active
- 2006-03-24 BR BRPI0609544A patent/BRPI0609544B8/pt active IP Right Grant
- 2006-03-24 DE DE602006015043T patent/DE602006015043D1/de active Active
- 2006-03-24 CA CA002602587A patent/CA2602587A1/en not_active Abandoned
- 2006-03-24 AT AT06748651T patent/ATE472099T1/de not_active IP Right Cessation
- 2006-03-24 MX MX2007012159A patent/MX2007012159A/es active IP Right Grant
- 2006-03-24 KR KR1020077025261A patent/KR101265362B1/ko active IP Right Grant
- 2006-03-24 JP JP2008504192A patent/JP5021614B2/ja active Active
-
2009
- 2009-02-24 US US12/391,293 patent/US20090218517A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DE602006015043D1 (de) | 2010-08-05 |
KR101265362B1 (ko) | 2013-05-20 |
EP2207026A1 (de) | 2010-07-14 |
EP1872112A1 (de) | 2008-01-02 |
MX2007012159A (es) | 2007-12-10 |
BRPI0609544B8 (pt) | 2021-07-27 |
BRPI0609544B1 (pt) | 2018-02-06 |
BRPI0609544A2 (pt) | 2011-10-18 |
JP2008537594A (ja) | 2008-09-18 |
AU2006232922A1 (en) | 2006-10-12 |
WO2006107619A1 (en) | 2006-10-12 |
US20060223169A1 (en) | 2006-10-05 |
US20090218517A1 (en) | 2009-09-03 |
KR20080014758A (ko) | 2008-02-14 |
EP1872112B1 (de) | 2010-06-23 |
CA2602587A1 (en) | 2006-10-12 |
US7507575B2 (en) | 2009-03-24 |
ES2347077T3 (es) | 2010-10-25 |
JP5021614B2 (ja) | 2012-09-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE472099T1 (de) | Multiplex-fluoreszenzdetektionsvorrichtung mit entfernbaren optischen modulen | |
ATE507473T1 (de) | Multiplex-fluoreszenznachweisvorrichtung mit mehreren über ein faserbündel an einen gemeinsamen detektor gekoppelten optischen modulen | |
TW200710381A (en) | Heating element for a rotating multiplex fluorescence detection device | |
TW200710394A (en) | Valve control system for a rotating multiplex fluorescence detection device | |
JP2008534966A5 (de) | ||
EP2201352B2 (de) | Fluoreszenzanregungs- und -nachweissystem und entsprechendes verfahren | |
JP2008537594A5 (de) | ||
US8802424B2 (en) | Methods and systems for analysis of fluorescent reactions with modulated excitation | |
CN104677870A (zh) | 一种超小型化多通道实时荧光光谱检测装置 | |
ATE357653T1 (de) | Fluoreszenzabbildung mittels telezentrischer anregungs- und abbildungsoptiken | |
EA201000526A1 (ru) | Спектрометр со светодиодной матрицей | |
EP1873512A3 (de) | Vorrichtung und Verfahren zur Erkennung von Fluoreszenzen in biologischen Proben | |
EP1830174A3 (de) | Optisches Mehrkanal-Fluoreszenzmesssystem und Mehrkanal-Fluoreszenzprobenanalysator | |
RU2013113957A (ru) | Однофотонный спектрометр | |
JP2012514747A5 (de) | ||
JP2013033008A (ja) | 光学分析装置及び光学分析方法 | |
WO2012170352A3 (en) | Multiplex fluorescent particle detection using spatially distributed excitation | |
CN204462019U (zh) | 一种超小型化多通道实时荧光光谱检测装置 | |
Kuang et al. | Photosynthetic Measurements with the Idea Spec: an Integrated Diode Emitter Array Spectrophotometer/Fluorometer | |
CN104267009A (zh) | 六色实时荧光定量pcr分析仪 | |
EP1964610A3 (de) | Nukleinsäureverstärker | |
RU2011127411A (ru) | Устройство для анализа люминесцирующих биологических микрочипов | |
US20120313008A1 (en) | Fluorescent detector | |
TW200710382A (en) | Multiplex fluorescence detection device having removable optical modules | |
TW200710393A (en) | Multiplex fluorescence detection device having fiber bundle coupling multiple optical modules to a common detector |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |