BRPI0609544B8 - dispositivo de detecção, sistema de detecção, e, método - Google Patents

dispositivo de detecção, sistema de detecção, e, método

Info

Publication number
BRPI0609544B8
BRPI0609544B8 BRPI0609544A BRPI0609544A BRPI0609544B8 BR PI0609544 B8 BRPI0609544 B8 BR PI0609544B8 BR PI0609544 A BRPI0609544 A BR PI0609544A BR PI0609544 A BRPI0609544 A BR PI0609544A BR PI0609544 B8 BRPI0609544 B8 BR PI0609544B8
Authority
BR
Brazil
Prior art keywords
species
optical modules
fluorescent light
detection
removable optical
Prior art date
Application number
BRPI0609544A
Other languages
English (en)
Inventor
W Robole Barry
D Ludowise Peter
Bedingham William
Original Assignee
3M Innovative Properties Co
Diasorin S P A
Quest Diagnostics Infectius Disease Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 3M Innovative Properties Co, Diasorin S P A, Quest Diagnostics Infectius Disease Inc filed Critical 3M Innovative Properties Co
Publication of BRPI0609544A2 publication Critical patent/BRPI0609544A2/pt
Publication of BRPI0609544B1 publication Critical patent/BRPI0609544B1/pt
Publication of BRPI0609544B8 publication Critical patent/BRPI0609544B8/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G01N35/00069—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides whereby the sample substrate is of the bio-disk type, i.e. having the format of an optical disk
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/173—Nucleic acid detection characterized by the use of physical, structural and functional properties staining/intercalating agent, e.g. ethidium bromide
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N2021/6417—Spectrofluorimetric devices
    • G01N2021/6419—Excitation at two or more wavelengths
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N2021/6417—Spectrofluorimetric devices
    • G01N2021/6421—Measuring at two or more wavelengths
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • G01N2021/6441—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks with two or more labels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/02—Mechanical
    • G01N2201/024—Modular construction

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

dispositivo de detecção, sistema de detecção, e, método. são descritas técnicas para a detecção de múltiplas espécies-alvo em pcr em tempo real (reação em cadeia da polimerase). por exemplo, um sistema compreende um dispositivo de aquisição de dado e um dispositivo de detecção acoplado com o dispositivo de aquisição de dado. o dispositivo de detecção inclui um disco rotativo tendo uma pluralidade de câmaras de processo tendo uma pluralidade de espécies que emitem luz fluorescente em diferentes comprimentos de onda. o dispositivo também inclui uma pluralidade de módulos ópticos removíveis. cada um dos módulos ópticos removíveis é opticamente configurado para excitar as espécies e capturar luz fluorescente emitida pelas espécies em diferentes comprimentos de onda. um feixe óptico de fibras acoplado com a pluralidade de módulos ópticos removíveis transmite a luz florescente a partir dos módulos ópticos para um único detector.
BRPI0609544A 2005-04-01 2006-03-24 dispositivo de detecção, sistema de detecção, e, método BRPI0609544B8 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US66746105P 2005-04-01 2005-04-01
US60/667461 2005-04-01
US11/174754 2005-07-05
US11/174,754 US7507575B2 (en) 2005-04-01 2005-07-05 Multiplex fluorescence detection device having removable optical modules
PCT/US2006/010787 WO2006107619A1 (en) 2005-04-01 2006-03-24 Multiplex fluorescence detection device having removable optical modules

Publications (3)

Publication Number Publication Date
BRPI0609544A2 BRPI0609544A2 (pt) 2011-10-18
BRPI0609544B1 BRPI0609544B1 (pt) 2018-02-06
BRPI0609544B8 true BRPI0609544B8 (pt) 2021-07-27

Family

ID=36591356

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0609544A BRPI0609544B8 (pt) 2005-04-01 2006-03-24 dispositivo de detecção, sistema de detecção, e, método

Country Status (12)

Country Link
US (2) US7507575B2 (pt)
EP (2) EP2207026A1 (pt)
JP (1) JP5021614B2 (pt)
KR (1) KR101265362B1 (pt)
AT (1) ATE472099T1 (pt)
AU (1) AU2006232922A1 (pt)
BR (1) BRPI0609544B8 (pt)
CA (1) CA2602587A1 (pt)
DE (1) DE602006015043D1 (pt)
ES (1) ES2347077T3 (pt)
MX (1) MX2007012159A (pt)
WO (1) WO2006107619A1 (pt)

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ATE472099T1 (de) 2010-07-15
JP5021614B2 (ja) 2012-09-12
US7507575B2 (en) 2009-03-24
KR101265362B1 (ko) 2013-05-20
BRPI0609544B1 (pt) 2018-02-06
US20060223169A1 (en) 2006-10-05
AU2006232922A1 (en) 2006-10-12
WO2006107619A1 (en) 2006-10-12
US20090218517A1 (en) 2009-09-03
CA2602587A1 (en) 2006-10-12
EP1872112A1 (en) 2008-01-02
ES2347077T3 (es) 2010-10-25
JP2008537594A (ja) 2008-09-18
BRPI0609544A2 (pt) 2011-10-18
EP2207026A1 (en) 2010-07-14
DE602006015043D1 (de) 2010-08-05
EP1872112B1 (en) 2010-06-23
MX2007012159A (es) 2007-12-10

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