ATE455861T1 - O-verknüpfte glykoformen von faktor vii und verfahren zu deren herstellung - Google Patents
O-verknüpfte glykoformen von faktor vii und verfahren zu deren herstellungInfo
- Publication number
- ATE455861T1 ATE455861T1 AT05766825T AT05766825T ATE455861T1 AT E455861 T1 ATE455861 T1 AT E455861T1 AT 05766825 T AT05766825 T AT 05766825T AT 05766825 T AT05766825 T AT 05766825T AT E455861 T1 ATE455861 T1 AT E455861T1
- Authority
- AT
- Austria
- Prior art keywords
- factor vii
- production
- linked glycoforms
- linked
- glycoforms
- Prior art date
Links
- 229940012413 factor vii Drugs 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 102100022641 Coagulation factor IX Human genes 0.000 abstract 1
- 102100023804 Coagulation factor VII Human genes 0.000 abstract 1
- 108010076282 Factor IX Proteins 0.000 abstract 1
- 108010023321 Factor VII Proteins 0.000 abstract 1
- 102000003886 Glycoproteins Human genes 0.000 abstract 1
- 108090000288 Glycoproteins Proteins 0.000 abstract 1
- 230000004989 O-glycosylation Effects 0.000 abstract 1
- 229960004222 factor ix Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biotechnology (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- General Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200400712 | 2004-05-04 | ||
| DKPA200400882 | 2004-06-04 | ||
| PCT/EP2005/052024 WO2005111225A1 (en) | 2004-05-04 | 2005-05-03 | O-linked glycoforms of polypeptides and method to manufacture them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE455861T1 true ATE455861T1 (de) | 2010-02-15 |
Family
ID=34968774
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05766825T ATE455861T1 (de) | 2004-05-04 | 2005-05-03 | O-verknüpfte glykoformen von faktor vii und verfahren zu deren herstellung |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US20080305518A1 (de) |
| EP (1) | EP1745141B2 (de) |
| JP (2) | JP5826446B2 (de) |
| KR (1) | KR20070008645A (de) |
| AT (1) | ATE455861T1 (de) |
| AU (1) | AU2005243427B2 (de) |
| BR (1) | BRPI0510295A (de) |
| CA (1) | CA2565414A1 (de) |
| DE (1) | DE602005019038D1 (de) |
| ES (1) | ES2339953T5 (de) |
| IL (1) | IL178541A0 (de) |
| MX (1) | MXPA06012676A (de) |
| NO (1) | NO20065512L (de) |
| RU (1) | RU2006138181A (de) |
| WO (1) | WO2005111225A1 (de) |
Families Citing this family (79)
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| CN102212019B (zh) | 2003-03-14 | 2015-05-27 | 蔚所番有限公司 | 支化水溶性聚合物及其缀合物 |
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| US8791070B2 (en) | 2003-04-09 | 2014-07-29 | Novo Nordisk A/S | Glycopegylated factor IX |
| WO2006127896A2 (en) | 2005-05-25 | 2006-11-30 | Neose Technologies, Inc. | Glycopegylated factor ix |
| MXPA05011832A (es) | 2003-05-09 | 2006-02-17 | Neose Technologies Inc | Composiciones y metodos para la preparacion de mutantes de glicosilacion de la hormona de crecimiento humano. |
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| US8633157B2 (en) | 2003-11-24 | 2014-01-21 | Novo Nordisk A/S | Glycopegylated erythropoietin |
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| US8930208B2 (en) | 2008-04-24 | 2015-01-06 | The Invention Science Fund I, Llc | Methods and systems for detecting a bioactive agent effect |
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| US9662391B2 (en) | 2008-04-24 | 2017-05-30 | The Invention Science Fund I Llc | Side effect ameliorating combination therapeutic products and systems |
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-
2005
- 2005-05-03 EP EP05766825.3A patent/EP1745141B2/de not_active Expired - Lifetime
- 2005-05-03 ES ES05766825T patent/ES2339953T5/es not_active Expired - Lifetime
- 2005-05-03 RU RU2006138181/13A patent/RU2006138181A/ru not_active Application Discontinuation
- 2005-05-03 MX MXPA06012676A patent/MXPA06012676A/es unknown
- 2005-05-03 DE DE602005019038T patent/DE602005019038D1/de not_active Expired - Lifetime
- 2005-05-03 CA CA002565414A patent/CA2565414A1/en not_active Abandoned
- 2005-05-03 WO PCT/EP2005/052024 patent/WO2005111225A1/en not_active Ceased
- 2005-05-03 BR BRPI0510295-2A patent/BRPI0510295A/pt not_active IP Right Cessation
- 2005-05-03 KR KR1020067021693A patent/KR20070008645A/ko not_active Withdrawn
- 2005-05-03 US US11/579,401 patent/US20080305518A1/en not_active Abandoned
- 2005-05-03 AT AT05766825T patent/ATE455861T1/de not_active IP Right Cessation
- 2005-05-03 AU AU2005243427A patent/AU2005243427B2/en not_active Expired - Fee Related
- 2005-05-03 JP JP2007512192A patent/JP5826446B2/ja not_active Expired - Fee Related
-
2006
- 2006-10-15 IL IL178541A patent/IL178541A0/en unknown
- 2006-11-29 NO NO20065512A patent/NO20065512L/no not_active Application Discontinuation
-
2010
- 2010-09-17 US US12/884,927 patent/US9023992B2/en active Active
-
2013
- 2013-12-02 JP JP2013249652A patent/JP2014088391A/ja not_active Withdrawn
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2017
- 2017-10-09 US US15/727,912 patent/US10844110B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1745141B1 (de) | 2010-01-20 |
| NO20065512L (no) | 2006-11-29 |
| KR20070008645A (ko) | 2007-01-17 |
| ES2339953T5 (es) | 2020-05-06 |
| US20180057566A1 (en) | 2018-03-01 |
| RU2006138181A (ru) | 2008-06-10 |
| AU2005243427A1 (en) | 2005-11-24 |
| US20080305518A1 (en) | 2008-12-11 |
| BRPI0510295A (pt) | 2007-11-06 |
| MXPA06012676A (es) | 2007-04-02 |
| JP2014088391A (ja) | 2014-05-15 |
| US9023992B2 (en) | 2015-05-05 |
| CA2565414A1 (en) | 2005-11-24 |
| IL178541A0 (en) | 2007-02-11 |
| WO2005111225A1 (en) | 2005-11-24 |
| JP2007536345A (ja) | 2007-12-13 |
| JP5826446B2 (ja) | 2015-12-02 |
| AU2005243427B2 (en) | 2010-07-22 |
| EP1745141B2 (de) | 2019-09-25 |
| US10844110B2 (en) | 2020-11-24 |
| DE602005019038D1 (de) | 2010-03-11 |
| EP1745141A1 (de) | 2007-01-24 |
| US20110064719A1 (en) | 2011-03-17 |
| ES2339953T3 (es) | 2010-05-27 |
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