BRPI0510295A - preparação de uma glicoproteìna, e, método para produzir a mesma - Google Patents

preparação de uma glicoproteìna, e, método para produzir a mesma

Info

Publication number
BRPI0510295A
BRPI0510295A BRPI0510295-2A BRPI0510295A BRPI0510295A BR PI0510295 A BRPI0510295 A BR PI0510295A BR PI0510295 A BRPI0510295 A BR PI0510295A BR PI0510295 A BRPI0510295 A BR PI0510295A
Authority
BR
Brazil
Prior art keywords
glycoprotein
producing
preparation
same
factor
Prior art date
Application number
BRPI0510295-2A
Other languages
English (en)
Inventor
Niels Kristian Klausen
Daniel Rasmussen
Original Assignee
Novo Nordisk Healthcare Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34968774&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0510295(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novo Nordisk Healthcare Ag filed Critical Novo Nordisk Healthcare Ag
Publication of BRPI0510295A publication Critical patent/BRPI0510295A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins

Abstract

PREPARAçãO DE UMA GLICOPROTEìNA, E, MéTODO PARA PRODUZIR A MESMA. A presente invenção diz respeito a composições que compreendem glicoproteínas tendo padrões alterados de glicosilação ligados em O, em particular o Fator VII e o Fator IX, e métodos para produzi-los.
BRPI0510295-2A 2004-05-04 2005-05-03 preparação de uma glicoproteìna, e, método para produzir a mesma BRPI0510295A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200400712 2004-05-04
DKPA200400882 2004-06-04
PCT/EP2005/052024 WO2005111225A1 (en) 2004-05-04 2005-05-03 O-linked glycoforms of polypeptides and method to manufacture them

Publications (1)

Publication Number Publication Date
BRPI0510295A true BRPI0510295A (pt) 2007-11-06

Family

ID=34968774

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0510295-2A BRPI0510295A (pt) 2004-05-04 2005-05-03 preparação de uma glicoproteìna, e, método para produzir a mesma

Country Status (15)

Country Link
US (3) US20080305518A1 (pt)
EP (1) EP1745141B2 (pt)
JP (2) JP5826446B2 (pt)
KR (1) KR20070008645A (pt)
AT (1) ATE455861T1 (pt)
AU (1) AU2005243427B2 (pt)
BR (1) BRPI0510295A (pt)
CA (1) CA2565414A1 (pt)
DE (1) DE602005019038D1 (pt)
ES (1) ES2339953T5 (pt)
IL (1) IL178541A0 (pt)
MX (1) MXPA06012676A (pt)
NO (1) NO20065512L (pt)
RU (1) RU2006138181A (pt)
WO (1) WO2005111225A1 (pt)

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UA86744C2 (en) 2002-06-21 2009-05-25 Ново Нордиск Хэлс Кеа Аг Pegylated factor vii glycoforms
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JP2006527216A (ja) 2003-06-13 2006-11-30 ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト 新規調合物
JP2007501812A (ja) 2003-08-08 2007-02-01 ノボ　ノルディスク　アクティーゼルスカブ ペプチドのための結合剤として新しい構造上十分に定義された枝分れしたポリマーの合成および適用
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ATE455861T1 (de) * 2004-05-04 2010-02-15 Novo Nordisk Healthcare Ag O-verknüpfte glykoformen von faktor vii und verfahren zu deren herstellung
ES2515915T3 (es) 2005-09-01 2014-10-30 Novo Nordisk Health Care Ag Purificación de los polipéptidos del Factor VII mediante cromatografía de interacción hidrofóbica

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AU2005243427A1 (en) 2005-11-24
JP2007536345A (ja) 2007-12-13
WO2005111225A1 (en) 2005-11-24
JP5826446B2 (ja) 2015-12-02
ES2339953T5 (es) 2020-05-06
ATE455861T1 (de) 2010-02-15
EP1745141A1 (en) 2007-01-24
US9023992B2 (en) 2015-05-05
EP1745141B2 (en) 2019-09-25
CA2565414A1 (en) 2005-11-24
ES2339953T3 (es) 2010-05-27
US20180057566A1 (en) 2018-03-01
NO20065512L (no) 2006-11-29
RU2006138181A (ru) 2008-06-10
JP2014088391A (ja) 2014-05-15
US10844110B2 (en) 2020-11-24
AU2005243427B2 (en) 2010-07-22
KR20070008645A (ko) 2007-01-17
EP1745141B1 (en) 2010-01-20
IL178541A0 (en) 2007-02-11
US20080305518A1 (en) 2008-12-11
US20110064719A1 (en) 2011-03-17
DE602005019038D1 (de) 2010-03-11

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