ATE414693T1 - Neuartige cis-imidazoline - Google Patents

Neuartige cis-imidazoline

Info

Publication number
ATE414693T1
ATE414693T1 AT05742255T AT05742255T ATE414693T1 AT E414693 T1 ATE414693 T1 AT E414693T1 AT 05742255 T AT05742255 T AT 05742255T AT 05742255 T AT05742255 T AT 05742255T AT E414693 T1 ATE414693 T1 AT E414693T1
Authority
AT
Austria
Prior art keywords
imidazolines
novel cis
cis
novel
Prior art date
Application number
AT05742255T
Other languages
English (en)
Inventor
Nader Fotouhi
Gregory Haley
Klaus Simonsen
Binh Vu
Stephen Webber
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE414693T1 publication Critical patent/ATE414693T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/22—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/26—Radicals substituted by carbon atoms having three bonds to hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT05742255T 2004-05-18 2005-05-10 Neuartige cis-imidazoline ATE414693T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US57227504P 2004-05-18 2004-05-18
US61553404P 2004-10-01 2004-10-01
US66877205P 2005-04-06 2005-04-06

Publications (1)

Publication Number Publication Date
ATE414693T1 true ATE414693T1 (de) 2008-12-15

Family

ID=35058746

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05742255T ATE414693T1 (de) 2004-05-18 2005-05-10 Neuartige cis-imidazoline

Country Status (21)

Country Link
US (2) US7964724B2 (de)
EP (1) EP1753727B1 (de)
JP (1) JP4814228B2 (de)
KR (3) KR20110033964A (de)
CN (1) CN1953965B (de)
AR (1) AR049545A1 (de)
AT (1) ATE414693T1 (de)
AU (1) AU2005243465B2 (de)
BR (1) BRPI0511328A (de)
CA (1) CA2565189A1 (de)
DE (1) DE602005011132D1 (de)
ES (1) ES2314660T3 (de)
IL (1) IL178884A (de)
MX (1) MXPA06013246A (de)
MY (1) MY143800A (de)
NO (1) NO20065730L (de)
PE (1) PE20060679A1 (de)
RU (1) RU2006144811A (de)
TW (1) TW200600501A (de)
WO (1) WO2005110996A1 (de)
ZA (1) ZA200609595B (de)

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WO2008065068A2 (en) * 2006-11-27 2008-06-05 Novartis Ag Substituted dihydroimidazoles and their use in the treatment of tumors
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CN101730708B (zh) 2007-03-28 2013-09-18 哈佛大学校长及研究员协会 缝合多肽
US7625895B2 (en) 2007-04-12 2009-12-01 Hoffmann-Le Roche Inc. Diphenyl-dihydro-imidazopyridinones
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US8629141B2 (en) 2011-05-11 2014-01-14 The Regents Of The University Of Michigan Spiro-oxindole MDM2 antagonists
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Also Published As

Publication number Publication date
US20090143364A1 (en) 2009-06-04
MY143800A (en) 2011-07-15
EP1753727A1 (de) 2007-02-21
US20050288287A1 (en) 2005-12-29
KR20080027969A (ko) 2008-03-28
AU2005243465A1 (en) 2005-11-24
EP1753727B1 (de) 2008-11-19
BRPI0511328A (pt) 2007-12-04
WO2005110996A1 (en) 2005-11-24
AU2005243465B2 (en) 2011-08-25
KR100832277B1 (ko) 2008-05-26
MXPA06013246A (es) 2007-02-08
CN1953965B (zh) 2012-07-04
IL178884A0 (en) 2007-03-08
KR20070011516A (ko) 2007-01-24
CA2565189A1 (en) 2005-11-24
PE20060679A1 (es) 2006-08-11
JP4814228B2 (ja) 2011-11-16
CN1953965A (zh) 2007-04-25
KR20110033964A (ko) 2011-04-01
RU2006144811A (ru) 2008-06-27
AR049545A1 (es) 2006-08-16
DE602005011132D1 (de) 2009-01-02
US7964724B2 (en) 2011-06-21
ES2314660T3 (es) 2009-03-16
TW200600501A (en) 2006-01-01
IL178884A (en) 2010-12-30
JP2007538022A (ja) 2007-12-27
ZA200609595B (en) 2008-06-25
NO20065730L (no) 2007-01-19

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