ATE413411T1 - Substituierte cycloalkyl p1' hepatitis c virus inhibitoren - Google Patents

Substituierte cycloalkyl p1' hepatitis c virus inhibitoren

Info

Publication number
ATE413411T1
ATE413411T1 AT03808384T AT03808384T ATE413411T1 AT E413411 T1 ATE413411 T1 AT E413411T1 AT 03808384 T AT03808384 T AT 03808384T AT 03808384 T AT03808384 T AT 03808384T AT E413411 T1 ATE413411 T1 AT E413411T1
Authority
AT
Austria
Prior art keywords
hepatitis
substituted cycloalkyl
virus inhibitors
analogs
virus
Prior art date
Application number
AT03808384T
Other languages
English (en)
Inventor
Jeffrey Campbell
Andrea Stanley D
Andrew Good
Jianqing Li
Fiona Mcphee
Amy Ripka
Paul Scola
Yong Tu
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of ATE413411T1 publication Critical patent/ATE413411T1/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0827Tripeptides containing heteroatoms different from O, S, or N
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0804Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0812Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
AT03808384T 2002-05-20 2003-05-20 Substituierte cycloalkyl p1' hepatitis c virus inhibitoren ATE413411T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US38214902P 2002-05-20 2002-05-20

Publications (1)

Publication Number Publication Date
ATE413411T1 true ATE413411T1 (de) 2008-11-15

Family

ID=32312406

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03808384T ATE413411T1 (de) 2002-05-20 2003-05-20 Substituierte cycloalkyl p1' hepatitis c virus inhibitoren

Country Status (11)

Country Link
US (1) US6878722B2 (de)
EP (1) EP1505945B1 (de)
JP (1) JP4271148B2 (de)
AT (1) ATE413411T1 (de)
AU (1) AU2003301959A1 (de)
DE (1) DE60324552D1 (de)
ES (1) ES2315568T3 (de)
IS (1) IS7531A (de)
NO (1) NO20044895L (de)
PL (1) PL213029B1 (de)
WO (1) WO2004043339A2 (de)

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AU2003301959A8 (en) 2004-06-03
NO20044895L (no) 2004-12-28
ES2315568T3 (es) 2009-04-01
WO2004043339A2 (en) 2004-05-27
PL213029B1 (pl) 2012-12-31
US20040077551A1 (en) 2004-04-22
JP4271148B2 (ja) 2009-06-03
JP2006501307A (ja) 2006-01-12
PL373374A1 (en) 2005-08-22
US6878722B2 (en) 2005-04-12
WO2004043339A3 (en) 2004-07-22
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EP1505945A4 (de) 2006-11-22
AU2003301959A1 (en) 2004-06-03

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