ATE405258T1 - Verfahren zur überwachung des blutflusses und der metabolischen aufnahme in gewebe mit radioaktiv markierter alkansäure - Google Patents

Verfahren zur überwachung des blutflusses und der metabolischen aufnahme in gewebe mit radioaktiv markierter alkansäure

Info

Publication number
ATE405258T1
ATE405258T1 AT04760019T AT04760019T ATE405258T1 AT E405258 T1 ATE405258 T1 AT E405258T1 AT 04760019 T AT04760019 T AT 04760019T AT 04760019 T AT04760019 T AT 04760019T AT E405258 T1 ATE405258 T1 AT E405258T1
Authority
AT
Austria
Prior art keywords
fatty acid
alkaneous
tissue
acid
blood flow
Prior art date
Application number
AT04760019T
Other languages
German (de)
English (en)
Inventor
David Elmaleh
Alan Fischman
Timothy Shoup
Original Assignee
Gen Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gen Hospital Corp filed Critical Gen Hospital Corp
Application granted granted Critical
Publication of ATE405258T1 publication Critical patent/ATE405258T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0402—Organic compounds carboxylic acid carriers, fatty acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
AT04760019T 2003-04-17 2004-04-19 Verfahren zur überwachung des blutflusses und der metabolischen aufnahme in gewebe mit radioaktiv markierter alkansäure ATE405258T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US46357403P 2003-04-17 2003-04-17

Publications (1)

Publication Number Publication Date
ATE405258T1 true ATE405258T1 (de) 2008-09-15

Family

ID=33310796

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04760019T ATE405258T1 (de) 2003-04-17 2004-04-19 Verfahren zur überwachung des blutflusses und der metabolischen aufnahme in gewebe mit radioaktiv markierter alkansäure

Country Status (9)

Country Link
US (9) US7494642B2 (enExample)
EP (1) EP1622602B1 (enExample)
JP (1) JP4633052B2 (enExample)
AT (1) ATE405258T1 (enExample)
AU (1) AU2004232297B2 (enExample)
CA (1) CA2522737C (enExample)
DE (1) DE602004015970D1 (enExample)
MX (1) MXPA05011189A (enExample)
WO (1) WO2004093650A2 (enExample)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2374743T3 (es) * 1995-12-01 2012-02-21 Molecular Insight Pharmaceuticals, Inc. Estereoisómeros de análogos de ácidos grasos para imagen de diagnóstico.
US8565860B2 (en) 2000-08-21 2013-10-22 Biosensors International Group, Ltd. Radioactive emission detector equipped with a position tracking system
US8489176B1 (en) 2000-08-21 2013-07-16 Spectrum Dynamics Llc Radioactive emission detector equipped with a position tracking system and utilization thereof with medical systems and in medical procedures
US8909325B2 (en) 2000-08-21 2014-12-09 Biosensors International Group, Ltd. Radioactive emission detector equipped with a position tracking system and utilization thereof with medical systems and in medical procedures
MXPA05011189A (es) * 2003-04-17 2006-05-25 Gen Hospital Corp Metodo para monitorear el flujo sanguineo y la captacion metabolica en el tejido con acido alcanoico radiomarcado.
US9040016B2 (en) 2004-01-13 2015-05-26 Biosensors International Group, Ltd. Diagnostic kit and methods for radioimaging myocardial perfusion
US7968851B2 (en) 2004-01-13 2011-06-28 Spectrum Dynamics Llc Dynamic spect camera
US8571881B2 (en) 2004-11-09 2013-10-29 Spectrum Dynamics, Llc Radiopharmaceutical dispensing, administration, and imaging
EP1709585B1 (en) 2004-01-13 2020-01-08 Spectrum Dynamics Medical Limited Multi-dimensional image reconstruction
US9470801B2 (en) 2004-01-13 2016-10-18 Spectrum Dynamics Llc Gating with anatomically varying durations
US8586932B2 (en) 2004-11-09 2013-11-19 Spectrum Dynamics Llc System and method for radioactive emission measurement
EP1778957A4 (en) 2004-06-01 2015-12-23 Biosensors Int Group Ltd OPTIMIZING THE MEASUREMENT OF RADIOACTIVE RADIATION ON SPECIAL BODY STRUCTURES
US8000773B2 (en) 2004-11-09 2011-08-16 Spectrum Dynamics Llc Radioimaging
US8615405B2 (en) 2004-11-09 2013-12-24 Biosensors International Group, Ltd. Imaging system customization using data from radiopharmaceutical-associated data carrier
EP1827505A4 (en) 2004-11-09 2017-07-12 Biosensors International Group, Ltd. Radioimaging
US9943274B2 (en) 2004-11-09 2018-04-17 Spectrum Dynamics Medical Limited Radioimaging using low dose isotope
US9316743B2 (en) 2004-11-09 2016-04-19 Biosensors International Group, Ltd. System and method for radioactive emission measurement
WO2008059489A2 (en) 2006-11-13 2008-05-22 Spectrum Dynamics Llc Radioimaging applications of and novel formulations of teboroxime
EP1909853B1 (en) 2005-07-19 2015-03-18 Biosensors International Group, Ltd. Imaging protocols
US8837793B2 (en) 2005-07-19 2014-09-16 Biosensors International Group, Ltd. Reconstruction stabilizer and active vision
GB0525949D0 (en) 2005-12-21 2006-02-01 Hammersmith Imanet Ltd Pet radiotracers
US20090177098A1 (en) * 2006-01-16 2009-07-09 Kousuke Yakubo Examination System and Examination Method
US8894974B2 (en) 2006-05-11 2014-11-25 Spectrum Dynamics Llc Radiopharmaceuticals for diagnosis and therapy
US9275451B2 (en) 2006-12-20 2016-03-01 Biosensors International Group, Ltd. Method, a system, and an apparatus for using and processing multidimensional data
US8521253B2 (en) 2007-10-29 2013-08-27 Spectrum Dynamics Llc Prostate imaging
WO2010129572A2 (en) * 2009-05-04 2010-11-11 Washington University Pet radiotracers for imaging fatty acid metablolism and storage
US20120237937A1 (en) * 2009-06-12 2012-09-20 University Of Louisville Research Foundation, Inc. Methods to detect cancer in animals
US8338788B2 (en) 2009-07-29 2012-12-25 Spectrum Dynamics Llc Method and system of optimized volumetric imaging
US20110110570A1 (en) * 2009-11-10 2011-05-12 Avi Bar-Shalev Apparatus and methods for generating a planar image
DE102010010666A1 (de) * 2010-03-01 2011-09-01 Sven Reske Diagnose und Therapie von Krebserkrankungen mittels Fettsäuren
RU2016112494A (ru) * 2013-09-06 2017-10-11 Конинклейке Филипс Н.В. Устройство обработки для обработки данных сердечной деятельности
WO2018089491A1 (en) * 2016-11-08 2018-05-17 The Regents Of The University Of California Methods for multi-dose synthesis of [f-18]fddnp for clinical settings
CN108727229B (zh) * 2017-04-17 2021-07-02 北京先通国际医药科技股份有限公司 一种修饰脂肪酸型pet试剂前体的新工艺路线
CA3106903A1 (en) * 2018-07-20 2020-01-23 Astellas Pharma Inc. Fatty acid derivative labeled with positron-emitting radionuclide
CN114945557B (zh) * 2020-01-17 2024-06-04 安斯泰来制药株式会社 由正电子放射性核素标记的脂肪酸衍生物
CN114700006B (zh) * 2022-06-07 2023-03-24 北京先通国际医药科技股份有限公司 一种液体组合物的生产设备及其制备方法和用途
CN114732918B (zh) * 2022-06-10 2022-09-13 北京先通国际医药科技股份有限公司 一种液体组合物的生产设备及其制备方法和用途
CN114736112A (zh) * 2022-06-14 2022-07-12 北京先通国际医药科技股份有限公司 一种心肌代谢pet显像剂的制备方法及用途
CN114773179B (zh) * 2022-06-23 2022-09-16 北京先通国际医药科技股份有限公司 一种化合物ⅰ液体组合物的制备方法、及其在心肌代谢pet显像上的用途
CN114796534B (zh) * 2022-06-23 2022-09-16 北京先通国际医药科技股份有限公司 包含化合物ⅰ的液体组合物、制备方法及用途
CN115141125B (zh) * 2022-07-22 2023-04-28 北京先通国际医药科技股份有限公司 一种修饰长链脂肪酸型pet试剂前体的合成方法及其用途
CN115181013B (zh) * 2022-07-22 2023-08-08 北京先通国际医药科技股份有限公司 修饰脂肪酸型pet试剂前体关键中间体的制备方法及其用途
CN116217356A (zh) * 2022-09-06 2023-06-06 北京先通国际医药科技股份有限公司 Pet前体关键中间体的异构体的合成方法及其用途
CN115970012A (zh) * 2023-03-16 2023-04-18 北京先通国际医药科技股份有限公司 正电子心肌脂肪酸代谢显像剂与正电子18f-fdg心肌葡萄糖显像剂用于pet联合显像的用途

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4119640A (en) * 1975-07-10 1978-10-10 Union Carbide Corporation Polymerizable epoxide-modified compositions
DE2828623C2 (de) * 1978-06-29 1983-11-17 Kernforschungsanlage Jülich GmbH, 5170 Jülich Mit radioaktivem Flour markierte C↓1↓↓6↓-bis C↓1↓↓8↓- Fettsäuren, ein Verfahren zu ihrer Herstellung sowie deren Verwendung
US4202902A (en) 1979-03-05 1980-05-13 Shell Oil Company Lipogenesis control by cyclopropane-carboxylic acids, esters and amides
US4524059A (en) * 1983-01-28 1985-06-18 The General Hospital Corporation Fatty acid analogs
US4933365A (en) * 1989-01-25 1990-06-12 American Home Products Corporation Phospholipase A2 inhibitors
DE4012405C1 (en) * 1990-04-19 1991-08-14 Forschungszentrum Juelich Gmbh, 5170 Juelich, De Radioisotope labelled oxiranyl carboxylic acid derivs. prodn. - by nucleophilic replacement of corresp. bromo or iodo substits. with radioactive alkali halide(s) in polar medium
ES2374743T3 (es) 1995-12-01 2012-02-21 Molecular Insight Pharmaceuticals, Inc. Estereoisómeros de análogos de ácidos grasos para imagen de diagnóstico.
IT1295658B1 (it) * 1997-09-29 1999-05-24 Menarini Ricerche Spa Composizioni farmaceutiche contenenti acido ricinoleico e loro uso per la terapia antifiammatoria ed analgesica
ATE337020T1 (de) * 1999-04-14 2006-09-15 Molecular Insight Pharm Inc Fettsaure analoge zur diagnose von kranzarterie erkrankungen
WO2004092184A1 (de) 2003-04-12 2004-10-28 Forschungszentrum Rossendorf E.V. Technetiummarkierte fettsäuren und deren verwendung für die myokarddiagnostik sowie verfahren zur herstellung der technetiummarkierten fettsäuren
MXPA05011189A (es) 2003-04-17 2006-05-25 Gen Hospital Corp Metodo para monitorear el flujo sanguineo y la captacion metabolica en el tejido con acido alcanoico radiomarcado.
KR101574279B1 (ko) * 2008-04-04 2015-12-04 어드밴스드 마이크로 디바이시즈, 인코포레이티드 앤티 엘리어싱을 위한 필터링 방법 및 장치

Also Published As

Publication number Publication date
JP2006524250A (ja) 2006-10-26
EP1622602B1 (en) 2008-08-20
MXPA05011189A (es) 2006-05-25
US8871179B2 (en) 2014-10-28
US20080213173A1 (en) 2008-09-04
US7790142B2 (en) 2010-09-07
EP1622602A2 (en) 2006-02-08
HK1083414A1 (en) 2006-06-30
WO2004093650A2 (en) 2004-11-04
US8268291B2 (en) 2012-09-18
AU2004232297B2 (en) 2010-11-04
CA2522737A1 (en) 2004-11-04
AU2004232297A1 (en) 2004-11-04
US20130052129A1 (en) 2013-02-28
US20080214853A1 (en) 2008-09-04
JP4633052B2 (ja) 2011-02-16
US20090156848A1 (en) 2009-06-18
US8309053B2 (en) 2012-11-13
US7494642B2 (en) 2009-02-24
EP1622602A4 (en) 2006-06-21
CA2522737C (en) 2017-06-06
US20080214851A1 (en) 2008-09-04
WO2004093650A3 (en) 2005-04-14
US20040253177A1 (en) 2004-12-16
US20080206135A1 (en) 2008-08-28
DE602004015970D1 (de) 2008-10-02
US20080213178A1 (en) 2008-09-04
US20080095702A1 (en) 2008-04-24

Similar Documents

Publication Publication Date Title
ATE405258T1 (de) Verfahren zur überwachung des blutflusses und der metabolischen aufnahme in gewebe mit radioaktiv markierter alkansäure
EA200401365A1 (ru) Способы лечения илеуса
DK1660528T3 (da) Mutein af tåre-lipocalin
DE602005012233D1 (de) Ap2-domäne-transkriptionsfaktor odp2 (ovule development protein 2) und verwendungsverfahren
DE60335552D1 (de) Neue zusammensetzung und verfahren zur behandlung von immunerkrankungen
EA200802213A1 (ru) Способы лечения заболеваний крови
DK1567667T3 (da) Behandling af Huntington's sygdom med EPA
EA200800908A1 (ru) Получение прегабалина и родственных соединений
FI964444A0 (fi) Yhdisteet, jotka sisältävät Michael-akseptorin, erityisesti maleiimi-imidi- tai maleiinihappojohdannaisen, ja jotka on sidottu kromoforiin ja niiden käyttö pitkään kestävissä auringonestokoostumuksissa
AR045595A1 (es) Composiciones utiles como inhibidores de proteinas quinasas
DE602005020269D1 (de) Verwendung von treprostinil zur behandlung von neuropathischen diabetischen fussgeschwüren
AR061500A1 (es) Un agente antidiabetico para el control de la hiperglucemia diabetica y de las complicaciones relacionadas con la diabetes
BRPI0510623A (pt) compostos de derivados de prolina e morfolina
DK0783486T3 (da) Hidtil ukendte prostaglandinsynthaseinhibitorer
CY1107196T1 (el) Υποκατεστημενα παραγωγα 2,4-διϋδρο-πυρρολο (3,4-β) -κινολιν-9-ονης χρησιμα ως αναστολεις της φωσφοδιεστερασης
EA200201214A1 (ru) Замещенные тиоацетамиды
BRPI0410979A (pt) composto, composição farmacêutica, e, métodos para tratar uma doença em um animal mediada pela catepsina s e para tratar um paciente submetido a uma terapia
AR068897A1 (es) Inhibidores de proteasoma
BRPI0314666B8 (pt) composição nutricional ou terapêutica utilizável para o tratamento de mamíferos para aumentar a atividade imune
ATE375810T1 (de) Cyanoamid-verbindungen als nützliche malonyl-coa decarboxylase-hemmer
EA200200232A1 (ru) Интерлейкин-5 ингибирующие производные 6-азаурацила
AR033957A1 (es) Nuevos compuestos
HRP20050743A2 (en) 3-(2-phenyl-oxazol-4-yl methoxy) cyclohexylmethoxy acetic acid derivates and related compounds used as ppar modulators for treating type 2 diabetes and arteriosclerosis
BRPI0417167A (pt) composições para animais de estimação compreendendo oligofrutose de cadeia curta
TR200100125T2 (tr) Çok döngülü tiyazolidin-2-iliden aminleri, bunların üretimi için yöntemler

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties