ATE405258T1 - Verfahren zur überwachung des blutflusses und der metabolischen aufnahme in gewebe mit radioaktiv markierter alkansäure - Google Patents
Verfahren zur überwachung des blutflusses und der metabolischen aufnahme in gewebe mit radioaktiv markierter alkansäureInfo
- Publication number
- ATE405258T1 ATE405258T1 AT04760019T AT04760019T ATE405258T1 AT E405258 T1 ATE405258 T1 AT E405258T1 AT 04760019 T AT04760019 T AT 04760019T AT 04760019 T AT04760019 T AT 04760019T AT E405258 T1 ATE405258 T1 AT E405258T1
- Authority
- AT
- Austria
- Prior art keywords
- fatty acid
- alkaneous
- tissue
- acid
- blood flow
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0402—Organic compounds carboxylic acid carriers, fatty acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US46357403P | 2003-04-17 | 2003-04-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE405258T1 true ATE405258T1 (de) | 2008-09-15 |
Family
ID=33310796
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT04760019T ATE405258T1 (de) | 2003-04-17 | 2004-04-19 | Verfahren zur überwachung des blutflusses und der metabolischen aufnahme in gewebe mit radioaktiv markierter alkansäure |
Country Status (10)
Country | Link |
---|---|
US (9) | US7494642B2 (de) |
EP (1) | EP1622602B1 (de) |
JP (1) | JP4633052B2 (de) |
AT (1) | ATE405258T1 (de) |
AU (1) | AU2004232297B2 (de) |
CA (1) | CA2522737C (de) |
DE (1) | DE602004015970D1 (de) |
HK (1) | HK1083414A1 (de) |
MX (1) | MXPA05011189A (de) |
WO (1) | WO2004093650A2 (de) |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2238860C (en) * | 1995-12-01 | 2009-01-13 | David R. Elmaleh | Stereoisomers of fatty acid analogs for diagnostic imaging |
US8565860B2 (en) | 2000-08-21 | 2013-10-22 | Biosensors International Group, Ltd. | Radioactive emission detector equipped with a position tracking system |
US8489176B1 (en) | 2000-08-21 | 2013-07-16 | Spectrum Dynamics Llc | Radioactive emission detector equipped with a position tracking system and utilization thereof with medical systems and in medical procedures |
US8909325B2 (en) | 2000-08-21 | 2014-12-09 | Biosensors International Group, Ltd. | Radioactive emission detector equipped with a position tracking system and utilization thereof with medical systems and in medical procedures |
WO2004093650A2 (en) * | 2003-04-17 | 2004-11-04 | The General Hospital Corporation | Method for monitoring blood flow and metabolic uptake in tissue with radiolabeled alkanoic acid |
US8586932B2 (en) | 2004-11-09 | 2013-11-19 | Spectrum Dynamics Llc | System and method for radioactive emission measurement |
US7176466B2 (en) | 2004-01-13 | 2007-02-13 | Spectrum Dynamics Llc | Multi-dimensional image reconstruction |
US9040016B2 (en) | 2004-01-13 | 2015-05-26 | Biosensors International Group, Ltd. | Diagnostic kit and methods for radioimaging myocardial perfusion |
US9470801B2 (en) | 2004-01-13 | 2016-10-18 | Spectrum Dynamics Llc | Gating with anatomically varying durations |
US8571881B2 (en) | 2004-11-09 | 2013-10-29 | Spectrum Dynamics, Llc | Radiopharmaceutical dispensing, administration, and imaging |
WO2007010534A2 (en) | 2005-07-19 | 2007-01-25 | Spectrum Dynamics Llc | Imaging protocols |
US7968851B2 (en) | 2004-01-13 | 2011-06-28 | Spectrum Dynamics Llc | Dynamic spect camera |
EP1778957A4 (de) | 2004-06-01 | 2015-12-23 | Biosensors Int Group Ltd | Optimierung der messung radioaktiver strahlung an besonderen körperstrukturen |
US8615405B2 (en) | 2004-11-09 | 2013-12-24 | Biosensors International Group, Ltd. | Imaging system customization using data from radiopharmaceutical-associated data carrier |
US8423125B2 (en) | 2004-11-09 | 2013-04-16 | Spectrum Dynamics Llc | Radioimaging |
EP1827505A4 (de) | 2004-11-09 | 2017-07-12 | Biosensors International Group, Ltd. | Radiodarstellung |
US9316743B2 (en) | 2004-11-09 | 2016-04-19 | Biosensors International Group, Ltd. | System and method for radioactive emission measurement |
US9943274B2 (en) | 2004-11-09 | 2018-04-17 | Spectrum Dynamics Medical Limited | Radioimaging using low dose isotope |
WO2008059489A2 (en) | 2006-11-13 | 2008-05-22 | Spectrum Dynamics Llc | Radioimaging applications of and novel formulations of teboroxime |
US8837793B2 (en) | 2005-07-19 | 2014-09-16 | Biosensors International Group, Ltd. | Reconstruction stabilizer and active vision |
GB0525949D0 (en) * | 2005-12-21 | 2006-02-01 | Hammersmith Imanet Ltd | Pet radiotracers |
US20090177098A1 (en) * | 2006-01-16 | 2009-07-09 | Kousuke Yakubo | Examination System and Examination Method |
US8894974B2 (en) | 2006-05-11 | 2014-11-25 | Spectrum Dynamics Llc | Radiopharmaceuticals for diagnosis and therapy |
WO2008075362A2 (en) | 2006-12-20 | 2008-06-26 | Spectrum Dynamics Llc | A method, a system, and an apparatus for using and processing multidimensional data |
US8521253B2 (en) | 2007-10-29 | 2013-08-27 | Spectrum Dynamics Llc | Prostate imaging |
BRPI1014538A2 (pt) * | 2009-05-04 | 2016-04-05 | Univ Washington | radiotraçadores pet para imagear metabolismo e armazenamento de ácido graxo |
WO2010144876A1 (en) * | 2009-06-12 | 2010-12-16 | University Of Louisville Research Foundation, Inc | Methods to detect cancer in animals |
US8338788B2 (en) | 2009-07-29 | 2012-12-25 | Spectrum Dynamics Llc | Method and system of optimized volumetric imaging |
US20110110570A1 (en) * | 2009-11-10 | 2011-05-12 | Avi Bar-Shalev | Apparatus and methods for generating a planar image |
DE102010010666A1 (de) * | 2010-03-01 | 2011-09-01 | Sven Reske | Diagnose und Therapie von Krebserkrankungen mittels Fettsäuren |
RU2016112494A (ru) * | 2013-09-06 | 2017-10-11 | Конинклейке Филипс Н.В. | Устройство обработки для обработки данных сердечной деятельности |
DK3538161T3 (da) * | 2016-11-08 | 2022-09-05 | Univ California | Fremgangsmåder til flerdosissyntese af [F-18]FDDNP til kliniske indstillinger |
CN108727229B (zh) * | 2017-04-17 | 2021-07-02 | 北京先通国际医药科技股份有限公司 | 一种修饰脂肪酸型pet试剂前体的新工艺路线 |
EP3825302A4 (de) * | 2018-07-20 | 2022-05-04 | Astellas Pharma Inc. | Mit positron-emittierendem radionuklid markiertes fettsäurederivat |
CN116351339A (zh) * | 2022-06-07 | 2023-06-30 | 北京先通国际医药科技股份有限公司 | 一种液体组合物的生产设备及其制备方法和用途 |
CN114732918B (zh) * | 2022-06-10 | 2022-09-13 | 北京先通国际医药科技股份有限公司 | 一种液体组合物的生产设备及其制备方法和用途 |
CN114736112A (zh) * | 2022-06-14 | 2022-07-12 | 北京先通国际医药科技股份有限公司 | 一种心肌代谢pet显像剂的制备方法及用途 |
CN114773179B (zh) * | 2022-06-23 | 2022-09-16 | 北京先通国际医药科技股份有限公司 | 一种化合物ⅰ液体组合物的制备方法、及其在心肌代谢pet显像上的用途 |
CN114796534B (zh) * | 2022-06-23 | 2022-09-16 | 北京先通国际医药科技股份有限公司 | 包含化合物ⅰ的液体组合物、制备方法及用途 |
CN115850224A (zh) * | 2022-07-22 | 2023-03-28 | 北京先通国际医药科技股份有限公司 | 一种修饰长链脂肪酸型pet试剂前体的合成方法及其用途 |
CN115181013B (zh) * | 2022-07-22 | 2023-08-08 | 北京先通国际医药科技股份有限公司 | 修饰脂肪酸型pet试剂前体关键中间体的制备方法及其用途 |
CN115141087B (zh) * | 2022-09-06 | 2023-03-24 | 北京先通国际医药科技股份有限公司 | Pet前体关键中间体的异构体的合成方法及其用途 |
CN115970012A (zh) * | 2023-03-16 | 2023-04-18 | 北京先通国际医药科技股份有限公司 | 正电子心肌脂肪酸代谢显像剂与正电子18f-fdg心肌葡萄糖显像剂用于pet联合显像的用途 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
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US4119640A (en) * | 1975-07-10 | 1978-10-10 | Union Carbide Corporation | Polymerizable epoxide-modified compositions |
DE2828623C2 (de) * | 1978-06-29 | 1983-11-17 | Kernforschungsanlage Jülich GmbH, 5170 Jülich | Mit radioaktivem Flour markierte C↓1↓↓6↓-bis C↓1↓↓8↓- Fettsäuren, ein Verfahren zu ihrer Herstellung sowie deren Verwendung |
US4202902A (en) | 1979-03-05 | 1980-05-13 | Shell Oil Company | Lipogenesis control by cyclopropane-carboxylic acids, esters and amides |
US4524059A (en) * | 1983-01-28 | 1985-06-18 | The General Hospital Corporation | Fatty acid analogs |
US4933365A (en) * | 1989-01-25 | 1990-06-12 | American Home Products Corporation | Phospholipase A2 inhibitors |
DE4012405C1 (en) * | 1990-04-19 | 1991-08-14 | Forschungszentrum Juelich Gmbh, 5170 Juelich, De | Radioisotope labelled oxiranyl carboxylic acid derivs. prodn. - by nucleophilic replacement of corresp. bromo or iodo substits. with radioactive alkali halide(s) in polar medium |
CA2238860C (en) | 1995-12-01 | 2009-01-13 | David R. Elmaleh | Stereoisomers of fatty acid analogs for diagnostic imaging |
IT1295658B1 (it) * | 1997-09-29 | 1999-05-24 | Menarini Ricerche Spa | Composizioni farmaceutiche contenenti acido ricinoleico e loro uso per la terapia antifiammatoria ed analgesica |
EP1173226B1 (de) | 1999-04-14 | 2006-08-23 | Molecular Insight Pharmaceuticals, Inc. | Fettsaure analoge zur diagnose von kranzarterie erkrankungen |
WO2004092184A1 (de) | 2003-04-12 | 2004-10-28 | Forschungszentrum Rossendorf E.V. | Technetiummarkierte fettsäuren und deren verwendung für die myokarddiagnostik sowie verfahren zur herstellung der technetiummarkierten fettsäuren |
WO2004093650A2 (en) | 2003-04-17 | 2004-11-04 | The General Hospital Corporation | Method for monitoring blood flow and metabolic uptake in tissue with radiolabeled alkanoic acid |
KR101574279B1 (ko) * | 2008-04-04 | 2015-12-04 | 어드밴스드 마이크로 디바이시즈, 인코포레이티드 | 앤티 엘리어싱을 위한 필터링 방법 및 장치 |
-
2004
- 2004-04-19 WO PCT/US2004/012084 patent/WO2004093650A2/en active Application Filing
- 2004-04-19 DE DE602004015970T patent/DE602004015970D1/de not_active Expired - Lifetime
- 2004-04-19 US US10/827,054 patent/US7494642B2/en not_active Expired - Fee Related
- 2004-04-19 JP JP2006513138A patent/JP4633052B2/ja not_active Expired - Fee Related
- 2004-04-19 EP EP04760019A patent/EP1622602B1/de not_active Expired - Fee Related
- 2004-04-19 MX MXPA05011189A patent/MXPA05011189A/es active IP Right Grant
- 2004-04-19 AU AU2004232297A patent/AU2004232297B2/en not_active Ceased
- 2004-04-19 AT AT04760019T patent/ATE405258T1/de not_active IP Right Cessation
- 2004-04-19 CA CA2522737A patent/CA2522737C/en not_active Expired - Fee Related
-
2006
- 2006-05-11 HK HK06105481.9A patent/HK1083414A1/xx not_active IP Right Cessation
-
2007
- 2007-10-10 US US11/973,810 patent/US20080214853A1/en not_active Abandoned
- 2007-10-11 US US11/973,921 patent/US20080095702A1/en not_active Abandoned
- 2007-10-11 US US11/973,922 patent/US8309053B2/en active Active
- 2007-10-11 US US11/973,925 patent/US20080213178A1/en not_active Abandoned
- 2007-10-11 US US11/974,139 patent/US7790142B2/en active Active
- 2007-10-11 US US11/973,926 patent/US20080214851A1/en not_active Abandoned
-
2009
- 2009-02-23 US US12/391,250 patent/US8268291B2/en active Active
-
2012
- 2012-08-27 US US13/595,546 patent/US8871179B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US20080095702A1 (en) | 2008-04-24 |
HK1083414A1 (en) | 2006-06-30 |
EP1622602B1 (de) | 2008-08-20 |
US8871179B2 (en) | 2014-10-28 |
JP2006524250A (ja) | 2006-10-26 |
US7494642B2 (en) | 2009-02-24 |
WO2004093650A3 (en) | 2005-04-14 |
US20080214853A1 (en) | 2008-09-04 |
AU2004232297B2 (en) | 2010-11-04 |
JP4633052B2 (ja) | 2011-02-16 |
EP1622602A4 (de) | 2006-06-21 |
US7790142B2 (en) | 2010-09-07 |
US20080213173A1 (en) | 2008-09-04 |
US20080206135A1 (en) | 2008-08-28 |
US20130052129A1 (en) | 2013-02-28 |
US20080213178A1 (en) | 2008-09-04 |
DE602004015970D1 (de) | 2008-10-02 |
WO2004093650A2 (en) | 2004-11-04 |
AU2004232297A1 (en) | 2004-11-04 |
US8268291B2 (en) | 2012-09-18 |
US20080214851A1 (en) | 2008-09-04 |
EP1622602A2 (de) | 2006-02-08 |
CA2522737A1 (en) | 2004-11-04 |
CA2522737C (en) | 2017-06-06 |
US20090156848A1 (en) | 2009-06-18 |
US8309053B2 (en) | 2012-11-13 |
US20040253177A1 (en) | 2004-12-16 |
MXPA05011189A (es) | 2006-05-25 |
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Legal Events
Date | Code | Title | Description |
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RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |