DE602004015970D1 - Verfahren zur überwachung des blutflusses und der metabolischen aufnahme in gewebe mit radioaktiv markierter alkansäure - Google Patents

Verfahren zur überwachung des blutflusses und der metabolischen aufnahme in gewebe mit radioaktiv markierter alkansäure

Info

Publication number
DE602004015970D1
DE602004015970D1 DE602004015970T DE602004015970T DE602004015970D1 DE 602004015970 D1 DE602004015970 D1 DE 602004015970D1 DE 602004015970 T DE602004015970 T DE 602004015970T DE 602004015970 T DE602004015970 T DE 602004015970T DE 602004015970 D1 DE602004015970 D1 DE 602004015970D1
Authority
DE
Germany
Prior art keywords
fatty acid
metabolic
inclusion
tissue
blood flow
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602004015970T
Other languages
German (de)
English (en)
Inventor
David R Elmaleh
Alan J Fischman
Timothy M Shoup
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Hospital Corp
Original Assignee
General Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by General Hospital Corp filed Critical General Hospital Corp
Publication of DE602004015970D1 publication Critical patent/DE602004015970D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0402—Organic compounds carboxylic acid carriers, fatty acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
DE602004015970T 2003-04-17 2004-04-19 Verfahren zur überwachung des blutflusses und der metabolischen aufnahme in gewebe mit radioaktiv markierter alkansäure Expired - Lifetime DE602004015970D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46357403P 2003-04-17 2003-04-17
PCT/US2004/012084 WO2004093650A2 (en) 2003-04-17 2004-04-19 Method for monitoring blood flow and metabolic uptake in tissue with radiolabeled alkanoic acid

Publications (1)

Publication Number Publication Date
DE602004015970D1 true DE602004015970D1 (de) 2008-10-02

Family

ID=33310796

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004015970T Expired - Lifetime DE602004015970D1 (de) 2003-04-17 2004-04-19 Verfahren zur überwachung des blutflusses und der metabolischen aufnahme in gewebe mit radioaktiv markierter alkansäure

Country Status (9)

Country Link
US (9) US7494642B2 (enExample)
EP (1) EP1622602B1 (enExample)
JP (1) JP4633052B2 (enExample)
AT (1) ATE405258T1 (enExample)
AU (1) AU2004232297B2 (enExample)
CA (1) CA2522737C (enExample)
DE (1) DE602004015970D1 (enExample)
MX (1) MXPA05011189A (enExample)
WO (1) WO2004093650A2 (enExample)

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WO2018089491A1 (en) * 2016-11-08 2018-05-17 The Regents Of The University Of California Methods for multi-dose synthesis of [f-18]fddnp for clinical settings
CN108727229B (zh) * 2017-04-17 2021-07-02 北京先通国际医药科技股份有限公司 一种修饰脂肪酸型pet试剂前体的新工艺路线
CA3106903A1 (en) * 2018-07-20 2020-01-23 Astellas Pharma Inc. Fatty acid derivative labeled with positron-emitting radionuclide
CN114945557B (zh) * 2020-01-17 2024-06-04 安斯泰来制药株式会社 由正电子放射性核素标记的脂肪酸衍生物
CN114700006B (zh) * 2022-06-07 2023-03-24 北京先通国际医药科技股份有限公司 一种液体组合物的生产设备及其制备方法和用途
CN114732918B (zh) * 2022-06-10 2022-09-13 北京先通国际医药科技股份有限公司 一种液体组合物的生产设备及其制备方法和用途
CN114736112A (zh) * 2022-06-14 2022-07-12 北京先通国际医药科技股份有限公司 一种心肌代谢pet显像剂的制备方法及用途
CN114773179B (zh) * 2022-06-23 2022-09-16 北京先通国际医药科技股份有限公司 一种化合物ⅰ液体组合物的制备方法、及其在心肌代谢pet显像上的用途
CN114796534B (zh) * 2022-06-23 2022-09-16 北京先通国际医药科技股份有限公司 包含化合物ⅰ的液体组合物、制备方法及用途
CN115141125B (zh) * 2022-07-22 2023-04-28 北京先通国际医药科技股份有限公司 一种修饰长链脂肪酸型pet试剂前体的合成方法及其用途
CN115181013B (zh) * 2022-07-22 2023-08-08 北京先通国际医药科技股份有限公司 修饰脂肪酸型pet试剂前体关键中间体的制备方法及其用途
CN116217356A (zh) * 2022-09-06 2023-06-06 北京先通国际医药科技股份有限公司 Pet前体关键中间体的异构体的合成方法及其用途
CN115970012A (zh) * 2023-03-16 2023-04-18 北京先通国际医药科技股份有限公司 正电子心肌脂肪酸代谢显像剂与正电子18f-fdg心肌葡萄糖显像剂用于pet联合显像的用途

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Also Published As

Publication number Publication date
JP2006524250A (ja) 2006-10-26
EP1622602B1 (en) 2008-08-20
MXPA05011189A (es) 2006-05-25
US8871179B2 (en) 2014-10-28
US20080213173A1 (en) 2008-09-04
US7790142B2 (en) 2010-09-07
EP1622602A2 (en) 2006-02-08
HK1083414A1 (en) 2006-06-30
WO2004093650A2 (en) 2004-11-04
US8268291B2 (en) 2012-09-18
AU2004232297B2 (en) 2010-11-04
CA2522737A1 (en) 2004-11-04
AU2004232297A1 (en) 2004-11-04
US20130052129A1 (en) 2013-02-28
US20080214853A1 (en) 2008-09-04
JP4633052B2 (ja) 2011-02-16
US20090156848A1 (en) 2009-06-18
US8309053B2 (en) 2012-11-13
US7494642B2 (en) 2009-02-24
EP1622602A4 (en) 2006-06-21
CA2522737C (en) 2017-06-06
US20080214851A1 (en) 2008-09-04
ATE405258T1 (de) 2008-09-15
WO2004093650A3 (en) 2005-04-14
US20040253177A1 (en) 2004-12-16
US20080206135A1 (en) 2008-08-28
US20080213178A1 (en) 2008-09-04
US20080095702A1 (en) 2008-04-24

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