AU2004232297B2 - Method for monitoring blood flow and metabolic uptake in tissue with radiolabeled alkanoic acid - Google Patents

Method for monitoring blood flow and metabolic uptake in tissue with radiolabeled alkanoic acid Download PDF

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Publication number
AU2004232297B2
AU2004232297B2 AU2004232297A AU2004232297A AU2004232297B2 AU 2004232297 B2 AU2004232297 B2 AU 2004232297B2 AU 2004232297 A AU2004232297 A AU 2004232297A AU 2004232297 A AU2004232297 A AU 2004232297A AU 2004232297 B2 AU2004232297 B2 AU 2004232297B2
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mtc
compound
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diseases
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AU2004232297A1 (en
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David R. Elmaleh
Alan J. Fischman
Timothy M. Shoup
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General Hospital Corp
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General Hospital Corp
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0402—Organic compounds carboxylic acid carriers, fatty acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
AU2004232297A 2003-04-17 2004-04-19 Method for monitoring blood flow and metabolic uptake in tissue with radiolabeled alkanoic acid Ceased AU2004232297B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US46357403P 2003-04-17 2003-04-17
US60/463.574 2003-04-17
PCT/US2004/012084 WO2004093650A2 (en) 2003-04-17 2004-04-19 Method for monitoring blood flow and metabolic uptake in tissue with radiolabeled alkanoic acid

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AU2004232297A1 AU2004232297A1 (en) 2004-11-04
AU2004232297B2 true AU2004232297B2 (en) 2010-11-04

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AU2004232297A Ceased AU2004232297B2 (en) 2003-04-17 2004-04-19 Method for monitoring blood flow and metabolic uptake in tissue with radiolabeled alkanoic acid

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US (9) US7494642B2 (enExample)
EP (1) EP1622602B1 (enExample)
JP (1) JP4633052B2 (enExample)
AT (1) ATE405258T1 (enExample)
AU (1) AU2004232297B2 (enExample)
CA (1) CA2522737C (enExample)
DE (1) DE602004015970D1 (enExample)
MX (1) MXPA05011189A (enExample)
WO (1) WO2004093650A2 (enExample)

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EP1778957A4 (en) 2004-06-01 2015-12-23 Biosensors Int Group Ltd OPTIMIZING THE MEASUREMENT OF RADIOACTIVE RADIATION ON SPECIAL BODY STRUCTURES
US8000773B2 (en) 2004-11-09 2011-08-16 Spectrum Dynamics Llc Radioimaging
US8615405B2 (en) 2004-11-09 2013-12-24 Biosensors International Group, Ltd. Imaging system customization using data from radiopharmaceutical-associated data carrier
EP1827505A4 (en) 2004-11-09 2017-07-12 Biosensors International Group, Ltd. Radioimaging
US9943274B2 (en) 2004-11-09 2018-04-17 Spectrum Dynamics Medical Limited Radioimaging using low dose isotope
US9316743B2 (en) 2004-11-09 2016-04-19 Biosensors International Group, Ltd. System and method for radioactive emission measurement
WO2008059489A2 (en) 2006-11-13 2008-05-22 Spectrum Dynamics Llc Radioimaging applications of and novel formulations of teboroxime
EP1909853B1 (en) 2005-07-19 2015-03-18 Biosensors International Group, Ltd. Imaging protocols
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US20090177098A1 (en) * 2006-01-16 2009-07-09 Kousuke Yakubo Examination System and Examination Method
US8894974B2 (en) 2006-05-11 2014-11-25 Spectrum Dynamics Llc Radiopharmaceuticals for diagnosis and therapy
US9275451B2 (en) 2006-12-20 2016-03-01 Biosensors International Group, Ltd. Method, a system, and an apparatus for using and processing multidimensional data
US8521253B2 (en) 2007-10-29 2013-08-27 Spectrum Dynamics Llc Prostate imaging
WO2010129572A2 (en) * 2009-05-04 2010-11-11 Washington University Pet radiotracers for imaging fatty acid metablolism and storage
US20120237937A1 (en) * 2009-06-12 2012-09-20 University Of Louisville Research Foundation, Inc. Methods to detect cancer in animals
US8338788B2 (en) 2009-07-29 2012-12-25 Spectrum Dynamics Llc Method and system of optimized volumetric imaging
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DE102010010666A1 (de) * 2010-03-01 2011-09-01 Sven Reske Diagnose und Therapie von Krebserkrankungen mittels Fettsäuren
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WO2018089491A1 (en) * 2016-11-08 2018-05-17 The Regents Of The University Of California Methods for multi-dose synthesis of [f-18]fddnp for clinical settings
CN108727229B (zh) * 2017-04-17 2021-07-02 北京先通国际医药科技股份有限公司 一种修饰脂肪酸型pet试剂前体的新工艺路线
CA3106903A1 (en) * 2018-07-20 2020-01-23 Astellas Pharma Inc. Fatty acid derivative labeled with positron-emitting radionuclide
CN114945557B (zh) * 2020-01-17 2024-06-04 安斯泰来制药株式会社 由正电子放射性核素标记的脂肪酸衍生物
CN114700006B (zh) * 2022-06-07 2023-03-24 北京先通国际医药科技股份有限公司 一种液体组合物的生产设备及其制备方法和用途
CN114732918B (zh) * 2022-06-10 2022-09-13 北京先通国际医药科技股份有限公司 一种液体组合物的生产设备及其制备方法和用途
CN114736112A (zh) * 2022-06-14 2022-07-12 北京先通国际医药科技股份有限公司 一种心肌代谢pet显像剂的制备方法及用途
CN114773179B (zh) * 2022-06-23 2022-09-16 北京先通国际医药科技股份有限公司 一种化合物ⅰ液体组合物的制备方法、及其在心肌代谢pet显像上的用途
CN114796534B (zh) * 2022-06-23 2022-09-16 北京先通国际医药科技股份有限公司 包含化合物ⅰ的液体组合物、制备方法及用途
CN115141125B (zh) * 2022-07-22 2023-04-28 北京先通国际医药科技股份有限公司 一种修饰长链脂肪酸型pet试剂前体的合成方法及其用途
CN115181013B (zh) * 2022-07-22 2023-08-08 北京先通国际医药科技股份有限公司 修饰脂肪酸型pet试剂前体关键中间体的制备方法及其用途
CN116217356A (zh) * 2022-09-06 2023-06-06 北京先通国际医药科技股份有限公司 Pet前体关键中间体的异构体的合成方法及其用途
CN115970012A (zh) * 2023-03-16 2023-04-18 北京先通国际医药科技股份有限公司 正电子心肌脂肪酸代谢显像剂与正电子18f-fdg心肌葡萄糖显像剂用于pet联合显像的用途

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Also Published As

Publication number Publication date
JP2006524250A (ja) 2006-10-26
EP1622602B1 (en) 2008-08-20
MXPA05011189A (es) 2006-05-25
US8871179B2 (en) 2014-10-28
US20080213173A1 (en) 2008-09-04
US7790142B2 (en) 2010-09-07
EP1622602A2 (en) 2006-02-08
HK1083414A1 (en) 2006-06-30
WO2004093650A2 (en) 2004-11-04
US8268291B2 (en) 2012-09-18
CA2522737A1 (en) 2004-11-04
AU2004232297A1 (en) 2004-11-04
US20130052129A1 (en) 2013-02-28
US20080214853A1 (en) 2008-09-04
JP4633052B2 (ja) 2011-02-16
US20090156848A1 (en) 2009-06-18
US8309053B2 (en) 2012-11-13
US7494642B2 (en) 2009-02-24
EP1622602A4 (en) 2006-06-21
CA2522737C (en) 2017-06-06
US20080214851A1 (en) 2008-09-04
ATE405258T1 (de) 2008-09-15
WO2004093650A3 (en) 2005-04-14
US20040253177A1 (en) 2004-12-16
US20080206135A1 (en) 2008-08-28
DE602004015970D1 (de) 2008-10-02
US20080213178A1 (en) 2008-09-04
US20080095702A1 (en) 2008-04-24

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