JP4633052B2 - 放射性同位元素で標識したアルカン酸を使用することによる血流および組織への代謝的取込みのモニター法 - Google Patents
放射性同位元素で標識したアルカン酸を使用することによる血流および組織への代謝的取込みのモニター法 Download PDFInfo
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- JP4633052B2 JP4633052B2 JP2006513138A JP2006513138A JP4633052B2 JP 4633052 B2 JP4633052 B2 JP 4633052B2 JP 2006513138 A JP2006513138 A JP 2006513138A JP 2006513138 A JP2006513138 A JP 2006513138A JP 4633052 B2 JP4633052 B2 JP 4633052B2
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- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0402—Organic compounds carboxylic acid carriers, fatty acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
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| ES2374743T3 (es) * | 1995-12-01 | 2012-02-21 | Molecular Insight Pharmaceuticals, Inc. | Estereoisómeros de análogos de ácidos grasos para imagen de diagnóstico. |
| US8565860B2 (en) | 2000-08-21 | 2013-10-22 | Biosensors International Group, Ltd. | Radioactive emission detector equipped with a position tracking system |
| US8489176B1 (en) | 2000-08-21 | 2013-07-16 | Spectrum Dynamics Llc | Radioactive emission detector equipped with a position tracking system and utilization thereof with medical systems and in medical procedures |
| US8909325B2 (en) | 2000-08-21 | 2014-12-09 | Biosensors International Group, Ltd. | Radioactive emission detector equipped with a position tracking system and utilization thereof with medical systems and in medical procedures |
| MXPA05011189A (es) * | 2003-04-17 | 2006-05-25 | Gen Hospital Corp | Metodo para monitorear el flujo sanguineo y la captacion metabolica en el tejido con acido alcanoico radiomarcado. |
| US9040016B2 (en) | 2004-01-13 | 2015-05-26 | Biosensors International Group, Ltd. | Diagnostic kit and methods for radioimaging myocardial perfusion |
| US7968851B2 (en) | 2004-01-13 | 2011-06-28 | Spectrum Dynamics Llc | Dynamic spect camera |
| US8571881B2 (en) | 2004-11-09 | 2013-10-29 | Spectrum Dynamics, Llc | Radiopharmaceutical dispensing, administration, and imaging |
| EP1709585B1 (en) | 2004-01-13 | 2020-01-08 | Spectrum Dynamics Medical Limited | Multi-dimensional image reconstruction |
| US9470801B2 (en) | 2004-01-13 | 2016-10-18 | Spectrum Dynamics Llc | Gating with anatomically varying durations |
| US8586932B2 (en) | 2004-11-09 | 2013-11-19 | Spectrum Dynamics Llc | System and method for radioactive emission measurement |
| EP1778957A4 (en) | 2004-06-01 | 2015-12-23 | Biosensors Int Group Ltd | OPTIMIZING THE MEASUREMENT OF RADIOACTIVE RADIATION ON SPECIAL BODY STRUCTURES |
| US8000773B2 (en) | 2004-11-09 | 2011-08-16 | Spectrum Dynamics Llc | Radioimaging |
| US8615405B2 (en) | 2004-11-09 | 2013-12-24 | Biosensors International Group, Ltd. | Imaging system customization using data from radiopharmaceutical-associated data carrier |
| EP1827505A4 (en) | 2004-11-09 | 2017-07-12 | Biosensors International Group, Ltd. | Radioimaging |
| US9943274B2 (en) | 2004-11-09 | 2018-04-17 | Spectrum Dynamics Medical Limited | Radioimaging using low dose isotope |
| US9316743B2 (en) | 2004-11-09 | 2016-04-19 | Biosensors International Group, Ltd. | System and method for radioactive emission measurement |
| WO2008059489A2 (en) | 2006-11-13 | 2008-05-22 | Spectrum Dynamics Llc | Radioimaging applications of and novel formulations of teboroxime |
| EP1909853B1 (en) | 2005-07-19 | 2015-03-18 | Biosensors International Group, Ltd. | Imaging protocols |
| US8837793B2 (en) | 2005-07-19 | 2014-09-16 | Biosensors International Group, Ltd. | Reconstruction stabilizer and active vision |
| GB0525949D0 (en) | 2005-12-21 | 2006-02-01 | Hammersmith Imanet Ltd | Pet radiotracers |
| US20090177098A1 (en) * | 2006-01-16 | 2009-07-09 | Kousuke Yakubo | Examination System and Examination Method |
| US8894974B2 (en) | 2006-05-11 | 2014-11-25 | Spectrum Dynamics Llc | Radiopharmaceuticals for diagnosis and therapy |
| US9275451B2 (en) | 2006-12-20 | 2016-03-01 | Biosensors International Group, Ltd. | Method, a system, and an apparatus for using and processing multidimensional data |
| US8521253B2 (en) | 2007-10-29 | 2013-08-27 | Spectrum Dynamics Llc | Prostate imaging |
| WO2010129572A2 (en) * | 2009-05-04 | 2010-11-11 | Washington University | Pet radiotracers for imaging fatty acid metablolism and storage |
| US20120237937A1 (en) * | 2009-06-12 | 2012-09-20 | University Of Louisville Research Foundation, Inc. | Methods to detect cancer in animals |
| US8338788B2 (en) | 2009-07-29 | 2012-12-25 | Spectrum Dynamics Llc | Method and system of optimized volumetric imaging |
| US20110110570A1 (en) * | 2009-11-10 | 2011-05-12 | Avi Bar-Shalev | Apparatus and methods for generating a planar image |
| DE102010010666A1 (de) * | 2010-03-01 | 2011-09-01 | Sven Reske | Diagnose und Therapie von Krebserkrankungen mittels Fettsäuren |
| RU2016112494A (ru) * | 2013-09-06 | 2017-10-11 | Конинклейке Филипс Н.В. | Устройство обработки для обработки данных сердечной деятельности |
| WO2018089491A1 (en) * | 2016-11-08 | 2018-05-17 | The Regents Of The University Of California | Methods for multi-dose synthesis of [f-18]fddnp for clinical settings |
| CN108727229B (zh) * | 2017-04-17 | 2021-07-02 | 北京先通国际医药科技股份有限公司 | 一种修饰脂肪酸型pet试剂前体的新工艺路线 |
| CA3106903A1 (en) * | 2018-07-20 | 2020-01-23 | Astellas Pharma Inc. | Fatty acid derivative labeled with positron-emitting radionuclide |
| CN114945557B (zh) * | 2020-01-17 | 2024-06-04 | 安斯泰来制药株式会社 | 由正电子放射性核素标记的脂肪酸衍生物 |
| CN114700006B (zh) * | 2022-06-07 | 2023-03-24 | 北京先通国际医药科技股份有限公司 | 一种液体组合物的生产设备及其制备方法和用途 |
| CN114732918B (zh) * | 2022-06-10 | 2022-09-13 | 北京先通国际医药科技股份有限公司 | 一种液体组合物的生产设备及其制备方法和用途 |
| CN114736112A (zh) * | 2022-06-14 | 2022-07-12 | 北京先通国际医药科技股份有限公司 | 一种心肌代谢pet显像剂的制备方法及用途 |
| CN114773179B (zh) * | 2022-06-23 | 2022-09-16 | 北京先通国际医药科技股份有限公司 | 一种化合物ⅰ液体组合物的制备方法、及其在心肌代谢pet显像上的用途 |
| CN114796534B (zh) * | 2022-06-23 | 2022-09-16 | 北京先通国际医药科技股份有限公司 | 包含化合物ⅰ的液体组合物、制备方法及用途 |
| CN115141125B (zh) * | 2022-07-22 | 2023-04-28 | 北京先通国际医药科技股份有限公司 | 一种修饰长链脂肪酸型pet试剂前体的合成方法及其用途 |
| CN115181013B (zh) * | 2022-07-22 | 2023-08-08 | 北京先通国际医药科技股份有限公司 | 修饰脂肪酸型pet试剂前体关键中间体的制备方法及其用途 |
| CN116217356A (zh) * | 2022-09-06 | 2023-06-06 | 北京先通国际医药科技股份有限公司 | Pet前体关键中间体的异构体的合成方法及其用途 |
| CN115970012A (zh) * | 2023-03-16 | 2023-04-18 | 北京先通国际医药科技股份有限公司 | 正电子心肌脂肪酸代谢显像剂与正电子18f-fdg心肌葡萄糖显像剂用于pet联合显像的用途 |
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| US4119640A (en) * | 1975-07-10 | 1978-10-10 | Union Carbide Corporation | Polymerizable epoxide-modified compositions |
| DE2828623C2 (de) * | 1978-06-29 | 1983-11-17 | Kernforschungsanlage Jülich GmbH, 5170 Jülich | Mit radioaktivem Flour markierte C↓1↓↓6↓-bis C↓1↓↓8↓- Fettsäuren, ein Verfahren zu ihrer Herstellung sowie deren Verwendung |
| US4202902A (en) | 1979-03-05 | 1980-05-13 | Shell Oil Company | Lipogenesis control by cyclopropane-carboxylic acids, esters and amides |
| US4524059A (en) * | 1983-01-28 | 1985-06-18 | The General Hospital Corporation | Fatty acid analogs |
| US4933365A (en) * | 1989-01-25 | 1990-06-12 | American Home Products Corporation | Phospholipase A2 inhibitors |
| DE4012405C1 (en) * | 1990-04-19 | 1991-08-14 | Forschungszentrum Juelich Gmbh, 5170 Juelich, De | Radioisotope labelled oxiranyl carboxylic acid derivs. prodn. - by nucleophilic replacement of corresp. bromo or iodo substits. with radioactive alkali halide(s) in polar medium |
| ES2374743T3 (es) | 1995-12-01 | 2012-02-21 | Molecular Insight Pharmaceuticals, Inc. | Estereoisómeros de análogos de ácidos grasos para imagen de diagnóstico. |
| IT1295658B1 (it) * | 1997-09-29 | 1999-05-24 | Menarini Ricerche Spa | Composizioni farmaceutiche contenenti acido ricinoleico e loro uso per la terapia antifiammatoria ed analgesica |
| ATE337020T1 (de) * | 1999-04-14 | 2006-09-15 | Molecular Insight Pharm Inc | Fettsaure analoge zur diagnose von kranzarterie erkrankungen |
| WO2004092184A1 (de) | 2003-04-12 | 2004-10-28 | Forschungszentrum Rossendorf E.V. | Technetiummarkierte fettsäuren und deren verwendung für die myokarddiagnostik sowie verfahren zur herstellung der technetiummarkierten fettsäuren |
| MXPA05011189A (es) | 2003-04-17 | 2006-05-25 | Gen Hospital Corp | Metodo para monitorear el flujo sanguineo y la captacion metabolica en el tejido con acido alcanoico radiomarcado. |
| KR101574279B1 (ko) * | 2008-04-04 | 2015-12-04 | 어드밴스드 마이크로 디바이시즈, 인코포레이티드 | 앤티 엘리어싱을 위한 필터링 방법 및 장치 |
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Also Published As
| Publication number | Publication date |
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| JP2006524250A (ja) | 2006-10-26 |
| EP1622602B1 (en) | 2008-08-20 |
| MXPA05011189A (es) | 2006-05-25 |
| US8871179B2 (en) | 2014-10-28 |
| US20080213173A1 (en) | 2008-09-04 |
| US7790142B2 (en) | 2010-09-07 |
| EP1622602A2 (en) | 2006-02-08 |
| HK1083414A1 (en) | 2006-06-30 |
| WO2004093650A2 (en) | 2004-11-04 |
| US8268291B2 (en) | 2012-09-18 |
| AU2004232297B2 (en) | 2010-11-04 |
| CA2522737A1 (en) | 2004-11-04 |
| AU2004232297A1 (en) | 2004-11-04 |
| US20130052129A1 (en) | 2013-02-28 |
| US20080214853A1 (en) | 2008-09-04 |
| US20090156848A1 (en) | 2009-06-18 |
| US8309053B2 (en) | 2012-11-13 |
| US7494642B2 (en) | 2009-02-24 |
| EP1622602A4 (en) | 2006-06-21 |
| CA2522737C (en) | 2017-06-06 |
| US20080214851A1 (en) | 2008-09-04 |
| ATE405258T1 (de) | 2008-09-15 |
| WO2004093650A3 (en) | 2005-04-14 |
| US20040253177A1 (en) | 2004-12-16 |
| US20080206135A1 (en) | 2008-08-28 |
| DE602004015970D1 (de) | 2008-10-02 |
| US20080213178A1 (en) | 2008-09-04 |
| US20080095702A1 (en) | 2008-04-24 |
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