ATE362474T1 - Pyrazolo(1,5-a)pyrimidine als hemmstoffe cyclin- abhängiger kinasen - Google Patents

Pyrazolo(1,5-a)pyrimidine als hemmstoffe cyclin- abhängiger kinasen

Info

Publication number
ATE362474T1
ATE362474T1 AT03796321T AT03796321T ATE362474T1 AT E362474 T1 ATE362474 T1 AT E362474T1 AT 03796321 T AT03796321 T AT 03796321T AT 03796321 T AT03796321 T AT 03796321T AT E362474 T1 ATE362474 T1 AT E362474T1
Authority
AT
Austria
Prior art keywords
cyclin
pyrazolo
pyrimidines
inhibitors
dependent kinases
Prior art date
Application number
AT03796321T
Other languages
German (de)
English (en)
Inventor
Timothy Guzi
Kamil Paruch
Michael Dwyer
Ronald Doll
Viyyoor Girijavallabhan
Carmen Alvarez
Tin-Yau Chan
Chad Knutson
Vincent Madison
Thierry Fischmann
Lawrence Dillard
Vinh Tran
Zhen Min He
Ray James
Haengsoon Park
Original Assignee
Schering Corp
Pharmacopeia Drug Discovery
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp, Pharmacopeia Drug Discovery filed Critical Schering Corp
Application granted granted Critical
Publication of ATE362474T1 publication Critical patent/ATE362474T1/de

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
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    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
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    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
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  • Chemical Kinetics & Catalysis (AREA)
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  • Biomedical Technology (AREA)
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  • Immunology (AREA)
  • Cardiology (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Molecular Biology (AREA)
  • Transplantation (AREA)
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AT03796321T 2002-09-04 2003-09-03 Pyrazolo(1,5-a)pyrimidine als hemmstoffe cyclin- abhängiger kinasen ATE362474T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US40802902P 2002-09-04 2002-09-04

Publications (1)

Publication Number Publication Date
ATE362474T1 true ATE362474T1 (de) 2007-06-15

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AT03796321T ATE362474T1 (de) 2002-09-04 2003-09-03 Pyrazolo(1,5-a)pyrimidine als hemmstoffe cyclin- abhängiger kinasen

Country Status (18)

Country Link
US (2) US7067661B2 (https=)
EP (1) EP1534712B1 (https=)
JP (2) JP4790265B2 (https=)
KR (1) KR20050033659A (https=)
CN (1) CN1701073B (https=)
AR (1) AR041133A1 (https=)
AT (1) ATE362474T1 (https=)
AU (1) AU2003298571B2 (https=)
CA (1) CA2497544C (https=)
DE (1) DE60313872T2 (https=)
ES (1) ES2283868T3 (https=)
MX (1) MXPA05002572A (https=)
MY (2) MY145332A (https=)
NZ (1) NZ539161A (https=)
PE (1) PE20041000A1 (https=)
TW (1) TWI329645B (https=)
WO (1) WO2004026229A2 (https=)
ZA (1) ZA200501846B (https=)

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