ATE359500T1 - Fluoreszenzabbildung mittels telezentrizität - Google Patents

Fluoreszenzabbildung mittels telezentrizität

Info

Publication number
ATE359500T1
ATE359500T1 AT05000863T AT05000863T ATE359500T1 AT E359500 T1 ATE359500 T1 AT E359500T1 AT 05000863 T AT05000863 T AT 05000863T AT 05000863 T AT05000863 T AT 05000863T AT E359500 T1 ATE359500 T1 AT E359500T1
Authority
AT
Austria
Prior art keywords
excitation
sites
present
imaging
fluorescence
Prior art date
Application number
AT05000863T
Other languages
English (en)
Inventor
Martin Gutekunst
Frank Guse
Hans-Georg Heckmann
Martin Hessling
Joachim Koenig
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE359500T1 publication Critical patent/ATE359500T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02—Details
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02—Details
    • G01J3/0205—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
    • G01J3/0208—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using focussing or collimating elements, e.g. lenses or mirrors; performing aberration correction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02—Details
    • G01J3/0205—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
    • G01J3/021—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using plane or convex mirrors, parallel phase plates, or particular reflectors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
    • G01J3/4406—Fluorescence spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6463—Optics
    • G01N2021/6478—Special lenses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G01N2035/00099—Characterised by type of test elements
    • G01N2035/00158—Elements containing microarrays, i.e. "biochip"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/028—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having reaction cells in the form of microtitration plates
AT05000863T 2005-01-18 2005-01-18 Fluoreszenzabbildung mittels telezentrizität ATE359500T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05000863A EP1681556B1 (de) 2005-01-18 2005-01-18 Fluoreszenzabbildung mittels Telezentrizität

Publications (1)

Publication Number Publication Date
ATE359500T1 true ATE359500T1 (de) 2007-05-15

Family

ID=34933341

Family Applications (2)

Application Number Title Priority Date Filing Date
AT05000863T ATE359500T1 (de) 2005-01-18 2005-01-18 Fluoreszenzabbildung mittels telezentrizität
AT06000788T ATE378582T1 (de) 2005-01-18 2006-01-14 Fluoreszenzabbildung mittels telezentrischer optiken auf anregungs- und abbildungsseite

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT06000788T ATE378582T1 (de) 2005-01-18 2006-01-14 Fluoreszenzabbildung mittels telezentrischer optiken auf anregungs- und abbildungsseite

Country Status (6)

Country Link
US (1) US7369227B2 (de)
EP (1) EP1681556B1 (de)
JP (1) JP4605713B2 (de)
AT (2) ATE359500T1 (de)
DE (2) DE602005000877T2 (de)
ES (2) ES2285578T3 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7858382B2 (en) * 2005-05-27 2010-12-28 Vidar Systems Corporation Sensing apparatus having rotating optical assembly
US7528374B2 (en) * 2006-03-03 2009-05-05 Vidar Systems Corporation Sensing apparatus having optical assembly that collimates emitted light for detection
EP2245197B1 (de) * 2008-02-07 2016-10-12 Whitespace Enterprise Corporation Verbesserungen bei und in verbindung mit der analyse
EP2108699B1 (de) 2008-04-08 2014-06-25 F.Hoffmann-La Roche Ag Vorrichtung zur analytischen Verarbeitung und Detektion
EP2148187A1 (de) 2008-07-25 2010-01-27 Roche Diagnostics GmbH Anregungs- und Abbildungsoptik für die Fluoreszenzdetektion
EP2393596B1 (de) * 2009-02-09 2016-09-28 Whitespace Enterprise Corporation Mikrofluidische vorrichtungen und verfahren zur bereitstellung einer archivierungsprobe
JP5623385B2 (ja) * 2009-03-26 2014-11-12 ユニバーサル・バイオ・リサーチ株式会社 反応光学測定装置およびその測定方法
WO2011031377A1 (en) 2009-09-09 2011-03-17 Helixis, Inc. Optical system for multiple reactions
DE102010035003B4 (de) * 2010-08-20 2015-08-06 PicoQuant GmbH. Unternehmen für optoelektronische Forschung und Entwicklung Räumlich und zeitlich hochauflösende Mikroskopie
WO2013060482A1 (de) * 2011-10-28 2013-05-02 Torsten Matthias Vorrichtung und verfahren zum nachweis von in biologischen oder chemischen proben vorliegenden substanzen
WO2013137247A1 (ja) * 2012-03-12 2013-09-19 三菱レイヨン株式会社 蛍光検出装置及び蛍光検出方法
GB201205607D0 (en) * 2012-03-29 2012-05-16 Ltd Technopath Distrib A fluorescence microtitre plate reader
DE102014108143A1 (de) * 2014-06-10 2015-12-10 Kist Europe-Korea Institute of Science and Technologie Europe Forschungsgesellschaft mbh An optical system for detecting fluorescent or luminescent signals of at least two samples
US9541750B2 (en) * 2014-06-23 2017-01-10 Li-Cor, Inc. Telecentric, wide-field fluorescence scanning systems and methods
KR102477339B1 (ko) * 2015-01-23 2022-12-14 바이엘 악티엔게젤샤프트 수성 시험에서 선충 및 다른 생물에 대한 활성 성분의 효과를 결정하기 위한 방법 및 장치
CN113049553A (zh) * 2015-02-06 2021-06-29 生命技术公司 用于评价生物样本的系统和方法
JP6707557B2 (ja) * 2015-03-18 2020-06-10 オプト・エンジニアリング・ソチエタ・ア・レスポンサビリタ・リミタータＯｐｔｏ Ｅｎｇｉｎｅｅｒｉｎｇ Ｓ．Ｒ．Ｌ． テレセントリックレンズ
DE102016200271A1 (de) * 2016-01-13 2017-07-13 Institut Dr. Foerster Gmbh & Co. Kg Vorrichtung zur Erzeugung und Messung einer Emission
EP3208604B1 (de) * 2016-02-22 2019-07-10 F. Hoffmann-La Roche AG Optik zur analyse von mikrovertiefungen
CN107817227B (zh) 2016-09-12 2020-08-28 台达电子国际（新加坡）私人有限公司 荧光检测装置
EP3312593A1 (de) 2016-10-20 2018-04-25 Hain Lifescience GmbH Verfahren und vorrichtung zur optischen anregung einer mehrzahl von analyten in einem array von reaktionsgefässen und zur erfassung von fluoreszenzlicht aus dem analyten
SG10201609334WA (en) 2016-11-08 2018-06-28 Delta Electronics Intl Singapore Pte Ltd Multi-Channel Fluorescence Detection Device
DE202017001026U1 (de) 2017-02-16 2017-04-25 Martin Hessling Vorrichtung zur einfachen und effizienten Fluoreszenzanregung in Realtime-Thermocyclern mit einer oder mehreren LEDs
TWI660218B (zh) * 2018-02-22 2019-05-21 致茂電子股份有限公司 自動化螢光檢測系統
SG10201801853WA (en) 2018-03-02 2019-10-30 Delta Electronics Int’L Singapore Pte Ltd Portable multi-color fluorescence detection device
JP6664462B2 (ja) * 2018-12-05 2020-03-13 日本板硝子株式会社 蛍光検出用光学装置
JP7160773B2 (ja) 2019-07-26 2022-10-25 富士フイルム株式会社 蛍光撮影装置
TWI722785B (zh) 2020-01-31 2021-03-21 台達電子工業股份有限公司 光學校正工具
JP2020106535A (ja) * 2020-02-18 2020-07-09 日本板硝子株式会社 蛍光検出用光学装置
DE102020108432A1 (de) 2020-03-25 2021-09-30 Jenoptik Optical Systems Gmbh Vorrichtung und Verfahren zur Lumineszenzanalyse mehrerer Proben
JP2023525904A (ja) 2020-05-19 2023-06-19 モラーレイ リサーチ インク． ランダムアクセスアルタイム定量的ポリメラーゼ連鎖反応（ｑＰＣＲ）リアクターシステム
CN112326610A (zh) * 2020-10-28 2021-02-05 瑞莱生物科技江苏有限公司 一种定量荧光检测光学装置
KR102409740B1 (ko) 2020-11-05 2022-06-20 (주)그린광학 텔레센트릭 광학계를 포함하는 형광 측정 장치
US11868049B2 (en) 2021-04-14 2024-01-09 Innovations In Optics, Inc. High uniformity telecentric illuminator

Family Cites Families (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1991866A (en) * 1933-08-31 1935-02-19 Ben Kapner Light projection lamp
DE3717274A1 (de) * 1987-05-22 1988-12-01 Sick Erwin Gmbh Optische fehlerinspektionsvorrichtung
US4999513A (en) * 1988-09-09 1991-03-12 Canon Kabushiki Kaisha Particle measuring apparatus
US5118801A (en) * 1988-09-30 1992-06-02 The Public Health Research Institute Nucleic acid process containing improved molecular switch
US5994056A (en) 1991-05-02 1999-11-30 Roche Molecular Systems, Inc. Homogeneous methods for nucleic acid amplification and detection
US5538848A (en) * 1994-11-16 1996-07-23 Applied Biosystems Division, Perkin-Elmer Corp. Method for detecting nucleic acid amplification using self-quenching fluorescence probe
US6060288A (en) * 1994-08-03 2000-05-09 Mosaic Technologies Method for performing amplification of nucleic acid on supports
JPH08172506A (ja) * 1994-09-27 1996-07-02 Canon Inc 画像読取装置
EP0746865B1 (de) * 1994-12-08 2003-03-26 Molecular Dynamics, Inc. System zur fluoreszenzabbildung unter verwendung eines objektivs mit makroabtastung
AU7598996A (en) * 1995-10-25 1997-05-15 University Of Washington Surface plasmon resonance probe systems based on a folded planar lightpipe
JP2000512744A (ja) * 1996-05-16 2000-09-26 アフィメトリックス，インコーポレイテッド 標識材料を検出するシステムおよび方法
EP0912760B1 (de) 1996-06-04 2005-11-09 University Of Utah Research Foundation Gerät und verfahren zur fluoreszenzmessung der dna-amplifikation
DE69735313T2 (de) 1996-06-04 2006-11-02 University Of Utah Research Foundation, Salt Lake City Fluoreszenz-Donor-Akzeptor Paar
CA2263226C (en) * 1996-08-16 2006-10-10 Imaging Research, Inc. A digital imaging system for assays in well plates, gels and blots
US5910940A (en) * 1996-10-08 1999-06-08 Polaroid Corporation Storage medium having a layer of micro-optical lenses each lens generating an evanescent field
JPH10176992A (ja) * 1996-12-17 1998-06-30 Hitachi Electron Eng Co Ltd Ｄｎａ塩基配列決定装置
US20030205681A1 (en) * 1998-07-22 2003-11-06 Ljl Biosystems, Inc. Evanescent field illumination devices and methods
DE19748211A1 (de) 1997-10-31 1999-05-06 Zeiss Carl Fa Optisches Array-System und Reader für Mikrotiterplatten
DE69942272D1 (de) * 1998-02-23 2010-06-02 Wisconsin Alumni Res Found Deranordnungen
US6198577B1 (en) * 1998-03-10 2001-03-06 Glaxo Wellcome, Inc. Doubly telecentric lens and imaging system for multiwell plates
US6140653A (en) 1998-03-27 2000-10-31 Vysis, Inc. Large-field fluorescence imaging apparatus
US6818437B1 (en) * 1998-05-16 2004-11-16 Applera Corporation Instrument for monitoring polymerase chain reaction of DNA
EP3093649B1 (de) * 1998-05-16 2019-05-08 Life Technologies Corporation Eine kombination einer reaktionsvorrichtung und eines optischen instruments zur überwachung von dns-polymerasekettenreaktionen
US6306589B1 (en) * 1998-05-27 2001-10-23 Vysis, Inc. Biological assays for analyte detection
GB9811483D0 (en) * 1998-05-29 1998-07-29 Photonic Research Systems Limi Luminescence assay using cyclical excitation wavelength sequence
JP2000074837A (ja) * 1998-08-31 2000-03-14 Fuji Photo Film Co Ltd 撮影装置
FI982005A (fi) * 1998-09-17 2000-03-18 Wallac Oy Näytteiden kuvantamislaite
GB9905954D0 (en) * 1999-03-16 1999-05-05 Cambridge Imaging Ltd Sample imaging
DE19919092A1 (de) * 1999-04-27 2000-11-02 Zeiss Carl Jena Gmbh Anordnung zur optischen Auswertung eines Gegenstandsarrays
US7410793B2 (en) * 1999-05-17 2008-08-12 Applera Corporation Optical instrument including excitation source
US7387891B2 (en) * 1999-05-17 2008-06-17 Applera Corporation Optical instrument including excitation source
DE20004826U1 (de) * 2000-03-16 2000-06-15 Schaefter & Kirchhoff Vorrichtung zur optischen Prüfung einer Münze
US20020005493A1 (en) * 2000-04-04 2002-01-17 Reese Steven A. Optical components for microarray analysis
JP2001311877A (ja) * 2000-04-27 2001-11-09 Hamamatsu Photonics Kk 撮像装置
ATE346540T1 (de) * 2000-05-19 2006-12-15 Coherent Gmbh Vorrichtung und verfahren zur erkennung von tumorösem gewebe
JP2002014044A (ja) 2000-06-29 2002-01-18 Nikon Corp 蛍光測定装置
ATE332398T1 (de) 2000-08-11 2006-07-15 Univ Utah Res Found Einfach markierte oligonukleotidsonden
JP2002148521A (ja) * 2000-11-14 2002-05-22 Nikon Corp 顕微鏡
US6650411B2 (en) * 2001-04-26 2003-11-18 Affymetrix, Inc. System, method, and product for pixel clocking in scanning of biological materials
JP3741051B2 (ja) * 2001-05-10 2006-02-01 横河電機株式会社 バイオチップ読取装置
JP4834242B2 (ja) * 2001-05-30 2011-12-14 オリンパス株式会社 蛍光読み取り装置
DE10127611C2 (de) * 2001-06-07 2003-08-07 Jena Optronik Gmbh Anordnung zum Anregen und Auslesen der Fluoreszenzstrahlung eines Probenträgers mit einer Vielzahl von Einzelproben
DE10131687A1 (de) 2001-06-29 2003-01-16 Eppendorf Ag Vorrichtung zur Durchführung von Nukleinsäure-Amplifikationsreaktionen bei gleichzeitiger Verfolgung der Bildung von Amplifikationsprodukten
JP3999479B2 (ja) * 2001-07-10 2007-10-31 オリンパス株式会社 光学装置
JP2003028797A (ja) * 2001-07-11 2003-01-29 Hitachi Software Eng Co Ltd 蛍光読み取り装置
DE10155142C2 (de) 2001-11-12 2003-09-04 Friz Biochem Gmbh Dunkelfeld-Abbildungsvorrichtung zur ortsaufgelösten Dunkelfeldabbildung einer flächigen Probe
DE10200499A1 (de) 2002-01-03 2003-07-10 Zeiss Carl Jena Gmbh Verfahren und/oder Anordnung zur Identifikation von fluoreszierenden, lumineszierenden und/oder absorbierenden Substanzen auf und/oder in Probenträgern
US20040126757A1 (en) * 2002-01-31 2004-07-01 Francesco Cerrina Method and apparatus for synthesis of arrays of DNA probes
DE10206004A1 (de) 2002-02-14 2003-08-28 Zeiss Carl Jena Gmbh Vorrichtung zur konfokalen optischen Mikroanalyse
JP2003294633A (ja) * 2002-03-29 2003-10-15 Otsuka Denshi Co Ltd 蛍光測定装置
WO2003090613A1 (en) * 2002-04-26 2003-11-06 Optiscan Pty Ltd Laser scanning confocal microscope with fibre bundle return
WO2003098279A2 (en) * 2002-05-17 2003-11-27 Applera Corporation Optical instrument includung excitation source
US6825930B2 (en) * 2002-06-04 2004-11-30 Cambridge Research And Instrumentation, Inc. Multispectral imaging system
US7130042B2 (en) * 2003-03-06 2006-10-31 Board Of Trustees Of The Leland Stanford Junior University Dual axis fluorescence microscope with modulated input
US7057720B2 (en) * 2003-06-24 2006-06-06 Corning Incorporated Optical interrogation system and method for using same
US20040263959A1 (en) * 2003-06-30 2004-12-30 Dixon Arthur E. Scanning beam optical imaging system for macroscopic imaging of an object
US7218446B2 (en) * 2003-08-27 2007-05-15 Biomedical Photometrics Inc. Imaging system having a fine focus
US7981362B2 (en) * 2003-11-04 2011-07-19 Meso Scale Technologies, Llc Modular assay plates, reader systems and methods for test measurements
US7295316B2 (en) * 2004-01-14 2007-11-13 Applera Corporation Fluorescent detector with automatic changing filters
WO2005081801A2 (en) * 2004-02-09 2005-09-09 Blueshift Biotechnologies, Inc. Methods and apparatus for scanning small sample volumes
US7280261B2 (en) * 2004-12-20 2007-10-09 Palo Alto Research Center Incorporated Method of scanning and light collection for a rare cell detector
ATE357653T1 (de) * 2005-01-18 2007-04-15 Hoffmann La Roche Fluoreszenzabbildung mittels telezentrischer anregungs- und abbildungsoptiken

Also Published As

Publication number Publication date
JP4605713B2 (ja) 2011-01-05
JP2006215025A (ja) 2006-08-17
DE602005000877T2 (de) 2007-12-20
DE602006000216D1 (de) 2007-12-27
ES2296231T3 (es) 2008-04-16
ATE378582T1 (de) 2007-11-15
EP1681556A1 (de) 2006-07-19
DE602006000216T2 (de) 2008-09-11
DE602005000877D1 (de) 2007-05-24
US7369227B2 (en) 2008-05-06
US20060194308A1 (en) 2006-08-31
ES2285578T3 (es) 2007-11-16
EP1681556B1 (de) 2007-04-11

Similar Documents

Publication Publication Date Title
ATE359500T1 (de) Fluoreszenzabbildung mittels telezentrizität
DE602005000749D1 (de) Fluoreszenzabbildung mittels telezentrischer Anregungs- und Abbildungsoptiken
JP2010032513A5 (de)
WO2005099394A3 (en) Methods and devices for microarray image analysis
GB2598498B (en) High performance fluorescence imaging module for genomic testing assay
EP2278303A3 (de) Verfahren und Vorrichtung für die genetische Multiplex-Analyse
SE0600642L (sv) Fluorescensläsare
GB2458855A (en) Detection device and methods of use
DK2082239T3 (da) Sekventiel analyse af biologiske prøver med intermediær blegning af fluorescerensdetektor
EP1830174A3 (de) Optisches Mehrkanal-Fluoreszenzmesssystem und Mehrkanal-Fluoreszenzprobenanalysator
ATE507473T1 (de) Multiplex-fluoreszenznachweisvorrichtung mit mehreren über ein faserbündel an einen gemeinsamen detektor gekoppelten optischen modulen
EP1873512A3 (de) Vorrichtung und Verfahren zur Erkennung von Fluoreszenzen in biologischen Proben
WO2004094977A3 (en) Detection, resolution, and identification of arrayed elements
EA201170517A1 (ru) Устройство анализа поверхности подложки
TW200710381A (en) Heating element for a rotating multiplex fluorescence detection device
BRPI0609544B8 (pt) dispositivo de detecção, sistema de detecção, e, método
WO2009038668A3 (en) Highly multiplexed confocal detection systems and methods of using same
ATE336721T1 (de) Hoch-durchsatz assay zur messung von zellulären antworten mit hilfe von mikroarrays
FR2882943B1 (fr) Appareil de traitement d'echantillons biologiques.
TW200636619A (en) Analysis processing method and device
FI20031357A0 (fi) Monikäyttöinen laitteisto näytteiden optiseen mittaukseen
ATE517332T1 (de) Vorrichtung und verfahren zur tiefenaufgelösten optischen erfassung einer probe
FR2890755B1 (fr) Dispositif optique d'observation d'une cible, multifonction
ATE353978T1 (de) Personalisierte mikroarrays and ihre verwendung zum nachweis von zielmolekülen
ATE546727T1 (de) Vorrichtung zur optischen anregung unter verwendung einer anordnung mit mehreren wellenlängen

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1681556

Country of ref document: EP