ATE358129T1 - 1,2,3,4,7,8-hexahydro-6h-c1,4)diazepinoc6,7,1- 1j)chinolinderivative als antipsychotika und mittel gegen obesitas - Google Patents
1,2,3,4,7,8-hexahydro-6h-c1,4)diazepinoc6,7,1- 1j)chinolinderivative als antipsychotika und mittel gegen obesitasInfo
- Publication number
- ATE358129T1 ATE358129T1 AT03747309T AT03747309T ATE358129T1 AT E358129 T1 ATE358129 T1 AT E358129T1 AT 03747309 T AT03747309 T AT 03747309T AT 03747309 T AT03747309 T AT 03747309T AT E358129 T1 ATE358129 T1 AT E358129T1
- Authority
- AT
- Austria
- Prior art keywords
- antipsychotics
- hexahydro
- quinoline derivatives
- obesity agents
- obesity
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/06—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Physical Education & Sports Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Pregnancy & Childbirth (AREA)
- Gastroenterology & Hepatology (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Dermatology (AREA)
- Gynecology & Obstetrics (AREA)
- Child & Adolescent Psychology (AREA)
- Psychology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US37615302P | 2002-04-25 | 2002-04-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE358129T1 true ATE358129T1 (de) | 2007-04-15 |
Family
ID=29270769
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT03747309T ATE358129T1 (de) | 2002-04-25 | 2003-04-24 | 1,2,3,4,7,8-hexahydro-6h-c1,4)diazepinoc6,7,1- 1j)chinolinderivative als antipsychotika und mittel gegen obesitas |
Country Status (17)
Country | Link |
---|---|
US (2) | US7071185B2 (de) |
EP (1) | EP1497294B1 (de) |
JP (1) | JP2005529894A (de) |
CN (2) | CN1955180A (de) |
AR (1) | AR039670A1 (de) |
AT (1) | ATE358129T1 (de) |
AU (1) | AU2003243160B2 (de) |
BR (1) | BR0309463A (de) |
CA (1) | CA2482455A1 (de) |
DE (1) | DE60312838T2 (de) |
DK (1) | DK1497294T3 (de) |
ES (1) | ES2282652T3 (de) |
MX (1) | MXPA04010374A (de) |
PT (1) | PT1497294E (de) |
SI (1) | SI1497294T1 (de) |
TW (1) | TW200307682A (de) |
WO (1) | WO2003091251A1 (de) |
Families Citing this family (26)
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TW200307540A (en) | 2002-04-25 | 2003-12-16 | Wyeth Corp | [1, 4]Diazocino[7, 8, 1-hi] indole derivatives as antipsychotic and antiobesity agents |
TWI312781B (en) | 2002-04-25 | 2009-08-01 | [1,4]diazepino[6,7,1-ij]quinoline derivatives as antipsychotic and antiobesity agents | |
JP5173190B2 (ja) | 2004-08-25 | 2013-03-27 | 武田薬品工業株式会社 | 腹圧性尿失禁の予防・治療剤及びそのスクリーニング方法 |
AR051946A1 (es) * | 2004-11-05 | 2007-02-21 | Wyeth Corp | Formulaciones de derivados de [1,4] diazepina [6,7,1-ij] quinolina |
PE20060939A1 (es) * | 2004-11-05 | 2006-11-10 | Wyeth Corp | Metabolitos derivados de [1,4] diazepin[6,7,1-ij] quinolina y procedimiento de preparacion |
GT200500317A (es) * | 2004-11-05 | 2006-10-27 | Proceso para preparar compuestos de quinolina y productos obtenidos de los mismos | |
AR054849A1 (es) | 2005-07-26 | 2007-07-18 | Wyeth Corp | Diazepinoquinolinas, sintesis de las mismas, e intermediarios para obtenerlas |
US20090203750A1 (en) * | 2005-08-24 | 2009-08-13 | Alan Kozikowski | 5-HT2C Receptor Agonists as Anorectic Agents |
TW200734334A (en) * | 2006-01-13 | 2007-09-16 | Wyeth Corp | Treatment of substance abuse |
KR20080110759A (ko) * | 2006-03-24 | 2008-12-19 | 와이어쓰 | 통증 치료 |
KR20080105104A (ko) * | 2006-03-24 | 2008-12-03 | 와이어쓰 | 우울증 치료를 위한 신규한 치료학적 병용제 |
CA2644618A1 (en) * | 2006-03-24 | 2007-10-04 | Wyeth | Methods for treating cognitive and other disorders |
JP5528699B2 (ja) | 2006-05-16 | 2014-06-25 | 武田薬品工業株式会社 | 縮合複素環化合物およびその用途 |
CL2008002777A1 (es) * | 2007-09-21 | 2010-01-22 | Wyeth Corp | Metodo de preparacion de compuestos diazepinoquinolinicos quirales por recristalizacion en un sistema de solvente ternario. |
US20100266504A1 (en) | 2007-11-15 | 2010-10-21 | Takahiro Matsumoto | Condensed pyridine derivative and use thereof |
US20120253036A1 (en) | 2009-12-11 | 2012-10-04 | Yukinori Nagakura | Agent for treating fibromyalgia |
EP2531485B1 (de) | 2010-02-04 | 2019-04-24 | The Board of Trustees of the University of Illionis | Hochselektive 5-ht(2c)-rezeptoragonisten mit antagonistenaktivität am 5-ht(2b)-rezeptor |
WO2012030953A1 (en) | 2010-09-01 | 2012-03-08 | Arena Pharmaceuticals, Inc. | 5-ht2c receptor agonists in the treatment of disorders ameliorated by reduction of norepinephrine level |
EP2824106B1 (de) * | 2012-03-06 | 2016-11-23 | Takeda Pharmaceutical Company Limited | Tricyclische verbindung |
US20140080813A1 (en) | 2012-09-14 | 2014-03-20 | AbbVie Deutschland GmbH & Co. KG | Tricyclic quinoline and quinoxaline derivatives |
AU2013314279B2 (en) | 2012-09-14 | 2017-11-02 | AbbVie Deutschland GmbH & Co. KG | Tricyclic quinoline and quinoxaline derivatives |
WO2015066344A1 (en) | 2013-11-01 | 2015-05-07 | Arena Pharmaceuticals, Inc. | 5-ht2c receptor agonists and compositions and methods of use |
EP3250549B1 (de) | 2015-01-29 | 2021-06-23 | The Board of Trustees of the University of Illinois | Cyclopropylmethanamine als selektive 5-ht (2c) rezeptoragonisten |
MA42527A (fr) * | 2015-07-31 | 2021-04-07 | Arena Pharm Inc | Agonistes de récepteur 5-ht2c et compositions et procédés d'utilisation |
US20210052600A1 (en) | 2017-12-27 | 2021-02-25 | Takeda Pharmaceutical Company Limited | Therapeutic agents for stress urinary incontinence and incotinence of feces |
US10829877B2 (en) * | 2018-08-27 | 2020-11-10 | Nippon Mayer Ltd. | Warp knitting machine, warp knitted fabric manufacturing method and warp knitted fabric |
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US50300A (en) * | 1865-10-03 | John h | ||
US422524A (en) * | 1890-03-04 | Marion c | ||
US3158619A (en) | 1962-06-14 | 1964-11-24 | Searle & Co | Certain sulfur-containing ortho-fused polycyclic pyrazole derivatives |
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US3335134A (en) | 1964-04-02 | 1967-08-08 | Sandoz Ag | Certain 3, 4-dihydrofluoreno[1, 9a, 9-e, f]1, 4-diazepin-3(2h)-ones |
US3296252A (en) | 1964-04-02 | 1967-01-03 | Sandoz Ag | Tetracyclic diazepinone compounds |
GB1120461A (en) | 1964-07-06 | 1968-07-17 | Manuf Prod Pharma | Derivatives of fluoreno-[1,9-ef]1,4-diazepine-1-oxide |
US3329676A (en) | 1964-11-09 | 1967-07-04 | American Home Prod | Fused 1, 4-diazepine ring systems |
US3417101A (en) | 1964-11-09 | 1968-12-17 | American Home Prod | Fused ring compounds |
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US3914250A (en) | 1974-08-01 | 1975-10-21 | American Home Prod | 1,4-Diazepino{8 6,5,4-jk{9 carbazoles |
DE2443567C3 (de) * | 1974-09-12 | 1980-04-10 | Hoechst Ag, 6000 Frankfurt | U3,4,7,8-Hexahydro-(6H)-pyrido- [U3-ef] -1,5benzodiazepin-2-one, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
SU930902A1 (ru) | 1980-12-18 | 1982-10-15 | Всесоюзный научно-исследовательский химико-фармацевтический институт им.Серго Орджоникидзе | Производные тиено [3,2=в] индола |
US4880814A (en) | 1987-11-13 | 1989-11-14 | Abbott Laboratories | 7-cycloalkyl naphthyridines |
GB8812636D0 (en) | 1988-05-27 | 1988-06-29 | Glaxo Group Ltd | Chemical compounds |
JPH0240379A (ja) | 1988-07-28 | 1990-02-09 | Wakunaga Pharmaceut Co Ltd | 新規キノロン誘導体 |
JPH02180885A (ja) | 1988-09-01 | 1990-07-13 | Glaxo Group Ltd | ラクタム誘導体 |
EP0377238A1 (de) * | 1988-12-22 | 1990-07-11 | Duphar International Research B.V | Annelierte Indolo(3,2-c)-lactame |
DE69016430T2 (de) | 1989-06-09 | 1995-06-01 | Upjohn Co | Heterozyklische amine mit zns-wirksamkeit. |
SE9500998D0 (sv) | 1995-03-19 | 1995-03-19 | Haakan Wilhelm Wikstroem | New sulfone ester analogues of iso-clozapine and related structures: atypical neuroleptics |
JPH10237073A (ja) | 1996-02-02 | 1998-09-08 | Sumitomo Pharmaceut Co Ltd | 新規な置換グアニジン誘導体およびその製法 |
NZ314105A (en) | 1996-02-02 | 1997-12-19 | Sumitomo Pharma | Guanidine derivative substituted with a substituted indole which is peri condensed with a heterocyclic ring |
AU710825B2 (en) | 1996-02-21 | 1999-09-30 | Darwin Discovery Limited | Quinolones and their therapeutic use |
EP0882047A1 (de) | 1996-02-21 | 1998-12-09 | Darwin Discovery Limited | Chinolone und ihre therapeutische verwendung |
CA2324474A1 (en) | 1998-06-22 | 1999-12-29 | Elan Pharmaceuticals, Inc. | Compounds for inhibiting beta-amyloid peptide release and/or its synthesis |
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KR20010108025A (ko) | 1998-12-17 | 2001-12-07 | 이곤 이 버그 | 5HT2C 효능제인2,3,4,4a-테트라하이드로-1H-피라지노(1,2-a)퀴녹살린-5(6H)온 유도체 |
US6455564B1 (en) | 1999-01-06 | 2002-09-24 | Pharmacia & Upjohn Company | Method of treating sexual disturbances |
AR023574A1 (es) | 1999-04-23 | 2002-09-04 | Pharmacia & Upjohn Co Llc | Compuestos de azepinindol tetraciclico,composiciones farmaceuticas y el uso de dichos compuestos para preparar un medicamento, e intermediarios |
CN1371374A (zh) | 1999-06-15 | 2002-09-25 | 杜邦药品公司 | 取代的杂环稠合γ-咔啉 |
GB9918965D0 (en) | 1999-08-11 | 1999-10-13 | Cerebrus Ltd | Chemical compounds xxi |
GB9918962D0 (en) | 1999-08-11 | 1999-10-13 | Cerebrus Ltd | Chemical compounds xxii |
JP2001089461A (ja) | 1999-09-24 | 2001-04-03 | Konica Corp | テトラヒドロナフトジアゼピン類の製造方法及びスクアリリウム染料の製造方法 |
US20030022918A1 (en) | 2000-02-29 | 2003-01-30 | Horak Ivan David | Farnesyl protein transferase inhibitor combinations with an her2 antibody |
US6410583B1 (en) | 2000-07-25 | 2002-06-25 | Merck Frosst Canada & Co. | Cyclopentanoindoles, compositions containing such compounds and methods of treatment |
US6858604B2 (en) | 2000-11-03 | 2005-02-22 | Wyeth | Cyclohepta[b][1,4]diazepino[6,7,1-hi]indoles and derivatives |
US6916922B2 (en) | 2000-11-03 | 2005-07-12 | Wyeth | Process for the preparation of 1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta [B] [1,4] diazepino- [6,7,1-hi] indole derivatives |
US7141563B2 (en) | 2000-11-03 | 2006-11-28 | Wyeth | Process for the preparation of 1, 2, 3, 4, 8, 9, 10, 10a-octahydro-7bH-cyclopenta[b] [1, 4]diazepino[6, 7, 1-hi] indole derivatives |
AR031198A1 (es) | 2000-11-03 | 2003-09-10 | Wyeth Corp | Procedimiento para la preparacion de derivados de ciclopenta(b)diazepino(6,7,1)indol |
US6784172B2 (en) | 2000-11-03 | 2004-08-31 | Wyeth | Processes for preparation of cyclopenta[b][1,4]diazepino[6,7,1-hi]indoles and derivatives |
DE60106641T2 (de) | 2000-11-03 | 2005-12-01 | Wyeth | Cyclopenta[b][1,4] diazepino[6,7,1-hi]indole als 5ht2c antagonisten |
US6777407B2 (en) | 2000-11-03 | 2004-08-17 | Wyeth | Cyclopenta[b][1,4]diazepino[6,7,1-hi]indoles and derivatives |
AU2002227170A1 (en) | 2000-11-03 | 2002-05-15 | Wyeth | Cycloalkyl(b)(1,4)diazepino(6,7,1-hi)indoles and derivatives |
AR031200A1 (es) | 2000-11-03 | 2003-09-10 | Wyeth Corp | Cicloocta [b] [1,4] diazepino [6,7,1-hi] indoles y derivados |
AR031201A1 (es) | 2000-11-03 | 2003-09-10 | Wyeth Corp | /1,4/diazepino/6,7,1-jk/carbazoles y derivados |
PL366627A1 (en) | 2000-12-20 | 2005-02-07 | Bristol-Myers Squibb Company | Substituted pyrroloquinolines and pyridoquinolines as serotonin agonists and antagonists |
EP1343791A2 (de) | 2000-12-20 | 2003-09-17 | Bristol-Myers Squibb Company | Substituierte tetrazyklische pyridoindole als serotonin agonisten und antagonisten |
BR0211559A (pt) | 2001-08-06 | 2004-07-13 | Upjohn Co | Compostos, composições de ligantes tetracìclicos terapeuticamente úteis e seus usos |
TW200307540A (en) | 2002-04-25 | 2003-12-16 | Wyeth Corp | [1, 4]Diazocino[7, 8, 1-hi] indole derivatives as antipsychotic and antiobesity agents |
TWI312781B (en) | 2002-04-25 | 2009-08-01 | [1,4]diazepino[6,7,1-ij]quinoline derivatives as antipsychotic and antiobesity agents |
-
2003
- 2003-04-22 TW TW092109348A patent/TW200307682A/zh unknown
- 2003-04-24 SI SI200330782T patent/SI1497294T1/sl unknown
- 2003-04-24 AR ARP030101431A patent/AR039670A1/es unknown
- 2003-04-24 JP JP2003587809A patent/JP2005529894A/ja not_active Ceased
- 2003-04-24 CN CNA2006101624667A patent/CN1955180A/zh not_active Withdrawn
- 2003-04-24 DE DE60312838T patent/DE60312838T2/de not_active Expired - Lifetime
- 2003-04-24 MX MXPA04010374A patent/MXPA04010374A/es active IP Right Grant
- 2003-04-24 WO PCT/US2003/012749 patent/WO2003091251A1/en active IP Right Grant
- 2003-04-24 AU AU2003243160A patent/AU2003243160B2/en not_active Ceased
- 2003-04-24 ES ES03747309T patent/ES2282652T3/es not_active Expired - Lifetime
- 2003-04-24 US US10/422,592 patent/US7071185B2/en not_active Expired - Fee Related
- 2003-04-24 CA CA002482455A patent/CA2482455A1/en not_active Abandoned
- 2003-04-24 PT PT03747309T patent/PT1497294E/pt unknown
- 2003-04-24 DK DK03747309T patent/DK1497294T3/da active
- 2003-04-24 AT AT03747309T patent/ATE358129T1/de not_active IP Right Cessation
- 2003-04-24 CN CNB038143410A patent/CN100379735C/zh not_active Expired - Fee Related
- 2003-04-24 EP EP03747309A patent/EP1497294B1/de not_active Expired - Lifetime
- 2003-04-24 BR BR0309463-4A patent/BR0309463A/pt not_active IP Right Cessation
-
2006
- 2006-03-16 US US11/377,489 patent/US20060154920A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
PT1497294E (pt) | 2007-06-12 |
JP2005529894A (ja) | 2005-10-06 |
DE60312838D1 (de) | 2007-05-10 |
DK1497294T3 (da) | 2007-07-16 |
AR039670A1 (es) | 2005-03-02 |
WO2003091251A1 (en) | 2003-11-06 |
TW200307682A (en) | 2003-12-16 |
US20060154920A1 (en) | 2006-07-13 |
AU2003243160A1 (en) | 2003-11-10 |
CN1955180A (zh) | 2007-05-02 |
EP1497294A1 (de) | 2005-01-19 |
EP1497294B1 (de) | 2007-03-28 |
DE60312838T2 (de) | 2008-01-10 |
US20040019040A1 (en) | 2004-01-29 |
US7071185B2 (en) | 2006-07-04 |
CA2482455A1 (en) | 2003-11-06 |
SI1497294T1 (sl) | 2007-08-31 |
ES2282652T3 (es) | 2007-10-16 |
BR0309463A (pt) | 2005-02-09 |
CN1662534A (zh) | 2005-08-31 |
AU2003243160B2 (en) | 2009-02-05 |
CN100379735C (zh) | 2008-04-09 |
MXPA04010374A (es) | 2005-02-03 |
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