ATE319475T1 - Microbielles wirkstoffabgabesystem - Google Patents
Microbielles wirkstoffabgabesystemInfo
- Publication number
- ATE319475T1 ATE319475T1 AT00982485T AT00982485T ATE319475T1 AT E319475 T1 ATE319475 T1 AT E319475T1 AT 00982485 T AT00982485 T AT 00982485T AT 00982485 T AT00982485 T AT 00982485T AT E319475 T1 ATE319475 T1 AT E319475T1
- Authority
- AT
- Austria
- Prior art keywords
- proteins
- allergic
- allergens
- subjects
- microorganisms
- Prior art date
Links
- 230000000813 microbial effect Effects 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 abstract 5
- 108090000623 proteins and genes Proteins 0.000 abstract 5
- 206010020751 Hypersensitivity Diseases 0.000 abstract 4
- 239000013566 allergen Substances 0.000 abstract 4
- 244000005700 microbiome Species 0.000 abstract 3
- 208000026935 allergic disease Diseases 0.000 abstract 2
- 230000000172 allergic effect Effects 0.000 abstract 2
- 230000007815 allergy Effects 0.000 abstract 2
- 230000002052 anaphylactic effect Effects 0.000 abstract 2
- 208000010668 atopic eczema Diseases 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 206010002198 Anaphylactic reaction Diseases 0.000 abstract 1
- 241000894006 Bacteria Species 0.000 abstract 1
- 241000192125 Firmicutes Species 0.000 abstract 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 abstract 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 230000036783 anaphylactic response Effects 0.000 abstract 1
- 208000003455 anaphylaxis Diseases 0.000 abstract 1
- 210000000612 antigen-presenting cell Anatomy 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 235000013305 food Nutrition 0.000 abstract 1
- 230000036039 immunity Effects 0.000 abstract 1
- 239000004816 latex Substances 0.000 abstract 1
- 229920000126 latex Polymers 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 210000001048 venom Anatomy 0.000 abstract 1
- 239000002435 venom Substances 0.000 abstract 1
- 231100000611 venom Toxicity 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5156—Animal cells expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US19503500P | 2000-04-06 | 2000-04-06 | |
US09/731,375 US8153414B2 (en) | 2000-04-06 | 2000-12-06 | Microbial delivery system |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE319475T1 true ATE319475T1 (de) | 2006-03-15 |
Family
ID=26890647
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00982485T ATE319475T1 (de) | 2000-04-06 | 2000-12-06 | Microbielles wirkstoffabgabesystem |
Country Status (11)
Country | Link |
---|---|
US (6) | US8153414B2 (de) |
EP (1) | EP1272213B1 (de) |
JP (3) | JP2004527450A (de) |
AT (1) | ATE319475T1 (de) |
AU (2) | AU1951001A (de) |
CA (1) | CA2403292C (de) |
CY (1) | CY1105216T1 (de) |
DE (1) | DE60026584T2 (de) |
DK (1) | DK1272213T3 (de) |
ES (1) | ES2260078T3 (de) |
WO (1) | WO2001066136A2 (de) |
Families Citing this family (52)
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JP2004527450A (ja) * | 2000-04-06 | 2004-09-09 | シーア ファーマスーティカルズ エルエルシー | 微生物送達システム |
US8246945B2 (en) * | 2000-04-06 | 2012-08-21 | University Of Arkansas | Methods and reagents for decreasing clinical reaction to allergy |
WO2001076642A1 (en) * | 2000-04-07 | 2001-10-18 | The Regents Of The University Of California | Synergistic improvements to polynucleotide vaccines |
WO2002039951A2 (en) * | 2000-11-15 | 2002-05-23 | Globe Immune, Inc. | Yeast-dentritic cell vaccines and uses thereof |
US7060687B2 (en) * | 2001-02-07 | 2006-06-13 | Genmont Biotechnology Co. | Live vaccines for allergy treatment |
KR101164509B1 (ko) | 2002-12-16 | 2012-07-10 | 글로브이뮨 | 면역 요법으로서의 효모계 백신 |
US8343502B2 (en) * | 2002-12-16 | 2013-01-01 | Globeimmune, Inc. | Yeast-based vaccines as immunotherapy |
US7439042B2 (en) * | 2002-12-16 | 2008-10-21 | Globeimmune, Inc. | Yeast-based therapeutic for chronic hepatitis C infection |
US20070231796A1 (en) * | 2003-09-17 | 2007-10-04 | The Regents Of The University Of California | Sensor and method for detection of a target substance |
JP5234445B2 (ja) * | 2004-10-05 | 2013-07-10 | 源一郎 杣 | 薬剤 |
JP2008516610A (ja) * | 2004-10-18 | 2008-05-22 | グローブイミューン,インコーポレイテッド | 酵母を用いた慢性c型肝炎感染の治療 |
US20100034840A1 (en) * | 2005-07-11 | 2010-02-11 | David Apelian | Compositions and methods for eliciting an immune response to escape mutants of targeted therapies |
US20070172503A1 (en) * | 2005-12-13 | 2007-07-26 | Mycologics,Inc. | Compositions and Methods to Elicit Immune Responses Against Pathogenic Organisms Using Yeast Based Vaccines |
US7745128B2 (en) * | 2006-03-27 | 2010-06-29 | Globeimmune, Inc. | Ras mutation and compositions and methods related thereto |
US20080124355A1 (en) | 2006-09-22 | 2008-05-29 | David Gordon Bermudes | Live bacterial vaccines for viral infection prophylaxis or treatment |
JP5570819B2 (ja) | 2007-02-02 | 2014-08-13 | グローブイミューン,インコーポレイテッド | 酵母を含む組成物および酵母を増殖させる方法 |
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WO2010033841A1 (en) | 2008-09-19 | 2010-03-25 | Globeimmune, Inc. | Immunotherapy for chronic hepatitis c virus infection |
US8241623B1 (en) | 2009-02-09 | 2012-08-14 | David Bermudes | Protease sensitivity expression system |
EP3320915A1 (de) | 2009-04-17 | 2018-05-16 | Globeimmune, Inc. | Kombinationsimmuntherapiezusammensetzungen gegen krebs sowie verfahren |
JP2012532933A (ja) * | 2009-07-13 | 2012-12-20 | ヴァックスジーン コーポレーション | 食用微生物を使用して生産し投与される経口ワクチン |
AU2010291985B2 (en) | 2009-09-14 | 2016-05-05 | The Regents Of The University Of Colorado | Modulation of yeast-based immunotherapy products and responses |
US9597379B1 (en) | 2010-02-09 | 2017-03-21 | David Gordon Bermudes | Protease inhibitor combination with therapeutic proteins including antibodies |
US8524220B1 (en) | 2010-02-09 | 2013-09-03 | David Gordon Bermudes | Protease inhibitor: protease sensitivity expression system composition and methods improving the therapeutic activity and specificity of proteins delivered by bacteria |
US8771669B1 (en) | 2010-02-09 | 2014-07-08 | David Gordon Bermudes | Immunization and/or treatment of parasites and infectious agents by live bacteria |
ES2696551T3 (es) | 2010-12-17 | 2019-01-16 | Globeimmune Inc | Composiciones y métodos para el tratamiento o la prevención de la infección por adenovirus-36 humano |
ES2643389T3 (es) | 2011-02-12 | 2017-11-22 | Globeimmune, Inc. | Producto terapéutico basado en levadura para infección por hepatitis B crónica |
EP3238731B1 (de) | 2011-03-17 | 2021-02-17 | Globeimmune, Inc. | Immuntherapeutische hefe-brachyury-zusammensetzungen |
WO2012174220A1 (en) | 2011-06-14 | 2012-12-20 | Globeimmune, Inc. | Yeast-based compositions and methods for the treatment or prevention of hepatitis delta virus infection |
BR112014003477B1 (pt) | 2011-08-17 | 2021-11-03 | Globeimmune, Inc. | Composição imunoterapêutica de muc1 de levedura |
US20130216589A1 (en) * | 2012-02-17 | 2013-08-22 | Rich Content Biotech INC. | Oral vaccine for aquatic animals |
EP2841098A4 (de) | 2012-04-23 | 2016-03-02 | Allertein Therapeutics Llc | Nanopartikel zur behandlung von allergien |
US9653272B2 (en) | 2012-06-26 | 2017-05-16 | Biodesix, Inc. | Mass-spectral method for selection, and de-selection, of cancer patients for treatment with immune response generating therapies |
WO2014049604A2 (en) * | 2012-09-05 | 2014-04-03 | Amrita Therapeutics Limited | A novel biomedical device for cancer therapy |
US9593339B1 (en) | 2013-02-14 | 2017-03-14 | David Gordon Bermudes | Bacteria carrying bacteriophage and protease inhibitors for the treatment of disorders and methods of treatment |
WO2014159609A1 (en) | 2013-03-14 | 2014-10-02 | Allergen Research Corporation | Peanut formulations and uses thereof |
DK3482771T3 (da) | 2013-03-14 | 2023-03-20 | Nestle Sa | Fremstilling af jordnøddeformuleringer til oral desensibilisering |
RU2679806C2 (ru) | 2013-03-19 | 2019-02-13 | Дзе Юнайтед Стейтс Оф Эмерика, Эз Репрезентед Бай Дзе Секретэри, Дипартмент Оф Хелт Энд Хьюман Сервисиз | Дрожжевая иммунотерапия хордомы |
WO2014160747A2 (en) | 2013-03-26 | 2014-10-02 | Globeimmune, Inc. | Compositions and methods for the treatment or prevention of human immunodeficiency virus infection |
CA2907915C (en) | 2013-04-03 | 2023-03-07 | Allertein Therapeutics, Llc | Immunomodulatory nanoparticle compositions comprising a plurality of nanoparticles comprising biodegradable or biocompatible polymers and hydrophilic and hydrophobic cellular components |
TWI654200B (zh) | 2013-08-30 | 2019-03-21 | 環球免疫公司 | 治療或預防結核病的組合物及方法 |
US11215615B2 (en) | 2014-04-03 | 2022-01-04 | AllerGenis LLC | Peptides, reagents and methods for detecting food allergy |
US10799567B2 (en) | 2014-04-11 | 2020-10-13 | Globeimmune, Inc. | Yeast-based immunotherapy and type I interferon sensitivity |
US11065313B2 (en) | 2015-08-03 | 2021-07-20 | Globeimmune, Inc. | Modified yeast-brachyury immunotherapeutic compositions |
US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
JP7376208B2 (ja) * | 2017-10-25 | 2023-11-08 | アレーロ セラピューティクス ビーヴイ | 抗原特異的製剤の投与による免疫疾患の治療 |
CN111344010A (zh) | 2017-11-02 | 2020-06-26 | 艾慕恩治疗公司 | 口服免疫治疗方法 |
WO2020231843A1 (en) | 2019-05-10 | 2020-11-19 | Aimmune Therapeutics, Inc. | Methods for improving the quality of life of a patient with a peanut allergy |
CA3170144A1 (en) * | 2020-02-06 | 2021-08-12 | AllerGenis LLC | Assays for detecting peanut allergies |
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- 2000-12-06 WO PCT/US2000/033121 patent/WO2001066136A2/en active IP Right Grant
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AU2001219510B2 (en) | 2007-06-14 |
DE60026584D1 (de) | 2006-05-04 |
CY1105216T1 (el) | 2010-03-03 |
US20130243814A1 (en) | 2013-09-19 |
EP1272213B1 (de) | 2006-03-08 |
AU1951001A (en) | 2001-09-17 |
ES2260078T3 (es) | 2006-11-01 |
US20110027298A1 (en) | 2011-02-03 |
JP2009242427A (ja) | 2009-10-22 |
US20130142817A1 (en) | 2013-06-06 |
US20030035810A1 (en) | 2003-02-20 |
CA2403292C (en) | 2011-02-08 |
US20040234548A1 (en) | 2004-11-25 |
US8815251B2 (en) | 2014-08-26 |
DK1272213T3 (da) | 2006-07-10 |
EP1272213A2 (de) | 2003-01-08 |
JP2012207032A (ja) | 2012-10-25 |
US20040208894A1 (en) | 2004-10-21 |
WO2001066136A2 (en) | 2001-09-13 |
DE60026584T2 (de) | 2007-03-08 |
CA2403292A1 (en) | 2001-09-13 |
JP2004527450A (ja) | 2004-09-09 |
US8153414B2 (en) | 2012-04-10 |
WO2001066136A3 (en) | 2001-12-27 |
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