DK1272213T3 - Mikrobielt afgivelsessystem - Google Patents
Mikrobielt afgivelsessystemInfo
- Publication number
- DK1272213T3 DK1272213T3 DK00982485T DK00982485T DK1272213T3 DK 1272213 T3 DK1272213 T3 DK 1272213T3 DK 00982485 T DK00982485 T DK 00982485T DK 00982485 T DK00982485 T DK 00982485T DK 1272213 T3 DK1272213 T3 DK 1272213T3
- Authority
- DK
- Denmark
- Prior art keywords
- proteins
- allergic
- allergens
- subjects
- microorganisms
- Prior art date
Links
- 230000000813 microbial effect Effects 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 abstract 5
- 108090000623 proteins and genes Proteins 0.000 abstract 5
- 206010020751 Hypersensitivity Diseases 0.000 abstract 4
- 239000013566 allergen Substances 0.000 abstract 4
- 244000005700 microbiome Species 0.000 abstract 3
- 208000026935 allergic disease Diseases 0.000 abstract 2
- 230000000172 allergic effect Effects 0.000 abstract 2
- 230000007815 allergy Effects 0.000 abstract 2
- 230000002052 anaphylactic effect Effects 0.000 abstract 2
- 208000010668 atopic eczema Diseases 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 206010002198 Anaphylactic reaction Diseases 0.000 abstract 1
- 241000894006 Bacteria Species 0.000 abstract 1
- 241000192125 Firmicutes Species 0.000 abstract 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 abstract 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 230000036783 anaphylactic response Effects 0.000 abstract 1
- 208000003455 anaphylaxis Diseases 0.000 abstract 1
- 210000000612 antigen-presenting cell Anatomy 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 235000013305 food Nutrition 0.000 abstract 1
- 230000036039 immunity Effects 0.000 abstract 1
- 239000004816 latex Substances 0.000 abstract 1
- 229920000126 latex Polymers 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 210000001048 venom Anatomy 0.000 abstract 1
- 239000002435 venom Substances 0.000 abstract 1
- 231100000611 venom Toxicity 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5156—Animal cells expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US19503500P | 2000-04-06 | 2000-04-06 | |
US09/731,375 US8153414B2 (en) | 2000-04-06 | 2000-12-06 | Microbial delivery system |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1272213T3 true DK1272213T3 (da) | 2006-07-10 |
Family
ID=26890647
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK00982485T DK1272213T3 (da) | 2000-04-06 | 2000-12-06 | Mikrobielt afgivelsessystem |
Country Status (11)
Country | Link |
---|---|
US (6) | US8153414B2 (da) |
EP (1) | EP1272213B1 (da) |
JP (3) | JP2004527450A (da) |
AT (1) | ATE319475T1 (da) |
AU (2) | AU2001219510B2 (da) |
CA (1) | CA2403292C (da) |
CY (1) | CY1105216T1 (da) |
DE (1) | DE60026584T2 (da) |
DK (1) | DK1272213T3 (da) |
ES (1) | ES2260078T3 (da) |
WO (1) | WO2001066136A2 (da) |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6698162B2 (en) * | 2000-03-23 | 2004-03-02 | Teikoku Pharma Usa, Inc. | Methods of producing a terminally sterilized topical patch preparation |
WO2001066136A2 (en) * | 2000-04-06 | 2001-09-13 | Panacea Pharmaceuticals, Llc. | Microbial delivery system |
US8246945B2 (en) * | 2000-04-06 | 2012-08-21 | University Of Arkansas | Methods and reagents for decreasing clinical reaction to allergy |
EP1278550A4 (en) * | 2000-04-07 | 2004-05-12 | Univ California | SYNERGISTIC IMPROVEMENTS OF POLYNUCLEOTIDE VACCINE |
US7083787B2 (en) * | 2000-11-15 | 2006-08-01 | Globeimmune, Inc. | Yeast-dendritic cell vaccines and uses thereof |
US7060687B2 (en) | 2001-02-07 | 2006-06-13 | Genmont Biotechnology Co. | Live vaccines for allergy treatment |
US7439042B2 (en) * | 2002-12-16 | 2008-10-21 | Globeimmune, Inc. | Yeast-based therapeutic for chronic hepatitis C infection |
US8343502B2 (en) * | 2002-12-16 | 2013-01-01 | Globeimmune, Inc. | Yeast-based vaccines as immunotherapy |
ES2676503T3 (es) * | 2002-12-16 | 2018-07-20 | Globeimmune, Inc. | Vacunas basadas en levadura como inmunoterapia |
US20070231796A1 (en) * | 2003-09-17 | 2007-10-04 | The Regents Of The University Of California | Sensor and method for detection of a target substance |
JP5234445B2 (ja) * | 2004-10-05 | 2013-07-10 | 源一郎 杣 | 薬剤 |
BRPI0516356A (pt) | 2004-10-18 | 2008-09-02 | Globeimmune Inc | terapia à base de levedura para infecções crÈnicas da hepatite c |
CA2614884A1 (en) * | 2005-07-11 | 2007-01-18 | Globeimmune, Inc | Compositions and methods for eliciting an immune response to escape mutants of targeted therapies |
US20070172503A1 (en) * | 2005-12-13 | 2007-07-26 | Mycologics,Inc. | Compositions and Methods to Elicit Immune Responses Against Pathogenic Organisms Using Yeast Based Vaccines |
CN101448848B (zh) * | 2006-03-27 | 2013-12-04 | 全球免疫股份有限公司 | Ras突变及其相关组合物和方法 |
US20080124355A1 (en) | 2006-09-22 | 2008-05-29 | David Gordon Bermudes | Live bacterial vaccines for viral infection prophylaxis or treatment |
JP5570819B2 (ja) * | 2007-02-02 | 2014-08-13 | グローブイミューン,インコーポレイテッド | 酵母を含む組成物および酵母を増殖させる方法 |
KR20100015661A (ko) * | 2007-03-19 | 2010-02-12 | 글로브이뮨 | 암의 표적 치료법의 돌연변이성 이탈의 표적 절제를 위한 조성물 및 방법 |
PT2244734T (pt) | 2008-02-01 | 2016-08-05 | Murdoch Childrens Res Inst | Método para induzir tolerância a um alérgeno |
WO2010033841A1 (en) | 2008-09-19 | 2010-03-25 | Globeimmune, Inc. | Immunotherapy for chronic hepatitis c virus infection |
US8241623B1 (en) | 2009-02-09 | 2012-08-14 | David Bermudes | Protease sensitivity expression system |
KR101781966B1 (ko) | 2009-04-17 | 2017-09-27 | 글로브이뮨 | 암에 대한 병용 면역요법 조성물 및 방법 |
US20120171230A1 (en) * | 2009-07-13 | 2012-07-05 | Vaxgene Corporation | Oral vaccines produced and administered using edible micro-organism |
EP2477647B1 (en) | 2009-09-14 | 2016-01-13 | The Regents of the University of Colorado | Modulation of yeast-based immunotherapy products and responses |
US9597379B1 (en) | 2010-02-09 | 2017-03-21 | David Gordon Bermudes | Protease inhibitor combination with therapeutic proteins including antibodies |
US8771669B1 (en) | 2010-02-09 | 2014-07-08 | David Gordon Bermudes | Immunization and/or treatment of parasites and infectious agents by live bacteria |
US8524220B1 (en) | 2010-02-09 | 2013-09-03 | David Gordon Bermudes | Protease inhibitor: protease sensitivity expression system composition and methods improving the therapeutic activity and specificity of proteins delivered by bacteria |
ES2696551T3 (es) | 2010-12-17 | 2019-01-16 | Globeimmune Inc | Composiciones y métodos para el tratamiento o la prevención de la infección por adenovirus-36 humano |
MA34956B1 (fr) | 2011-02-12 | 2014-03-01 | Globeimmune Inc | Therapeutique a base de levure pour infection chronique par l'hepatite b |
MX350661B (es) | 2011-03-17 | 2017-09-13 | Us Health | Composiciones inmunoterapeuticas de levadura-brachyuri. |
EP2720716B1 (en) | 2011-06-14 | 2018-03-21 | Globeimmune, Inc. | Immunotherapeutic compositions for the treatment or prevention of hepatitis delta virus infection |
CN114617958A (zh) | 2011-08-17 | 2022-06-14 | 全球免疫股份有限公司 | 酵母-muc1免疫治疗组合物及其用途 |
US20130216589A1 (en) * | 2012-02-17 | 2013-08-22 | Rich Content Biotech INC. | Oral vaccine for aquatic animals |
US9597385B2 (en) | 2012-04-23 | 2017-03-21 | Allertein Therapeutics, Llc | Nanoparticles for treatment of allergy |
US9653272B2 (en) | 2012-06-26 | 2017-05-16 | Biodesix, Inc. | Mass-spectral method for selection, and de-selection, of cancer patients for treatment with immune response generating therapies |
WO2014049604A2 (en) * | 2012-09-05 | 2014-04-03 | Amrita Therapeutics Limited | A novel biomedical device for cancer therapy |
US9593339B1 (en) | 2013-02-14 | 2017-03-14 | David Gordon Bermudes | Bacteria carrying bacteriophage and protease inhibitors for the treatment of disorders and methods of treatment |
US9492535B2 (en) | 2013-03-14 | 2016-11-15 | Aimmune Therapeutics, Inc. | Peanut formulations and uses thereof |
US9198869B2 (en) | 2013-03-14 | 2015-12-01 | Aimmune Therapeutics, Inc. | Manufacture of peanut formulations for oral desensitization |
CA2907560C (en) | 2013-03-19 | 2021-12-07 | Timothy C. Rodell | Yeast-based immunotherapy for chordoma |
EP2978449B1 (en) | 2013-03-26 | 2021-09-08 | Globeimmune, Inc. | Compositions and methods for the treatment or prevention of human immunodeficiency virus infection |
WO2014165679A1 (en) | 2013-04-03 | 2014-10-09 | Allertein Therapeutics, Llc | Novel nanoparticle compositions |
TWI654200B (zh) | 2013-08-30 | 2019-03-21 | 環球免疫公司 | 治療或預防結核病的組合物及方法 |
EP3126837B1 (en) | 2014-04-03 | 2021-09-15 | AllerGenis, LLC | Peptides and methods for detecting food allergy |
CN113419058A (zh) | 2014-04-11 | 2021-09-21 | 全球免疫股份有限公司 | 基于酵母的免疫疗法和i型干扰素敏感性 |
TWI748957B (zh) | 2015-08-03 | 2021-12-11 | 美商環球免疫公司 | 經修飾之酵母-短尾畸型(Brachyury)免疫治療組合物 |
US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
JP7376208B2 (ja) | 2017-10-25 | 2023-11-08 | アレーロ セラピューティクス ビーヴイ | 抗原特異的製剤の投与による免疫疾患の治療 |
WO2019089978A1 (en) | 2017-11-02 | 2019-05-09 | Aimmune Therapeutics, Inc. | Methods of oral immunotherapy |
CN113966229A (zh) | 2019-05-10 | 2022-01-21 | 爱沐疗法公司 | 用于改善花生过敏患者的生活质量的方法 |
JP2023514162A (ja) * | 2020-02-06 | 2023-04-05 | アラージェニス エルエルシー | ピーナッツアレルギーを検出するためのアッセイ |
Family Cites Families (104)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US588799A (en) * | 1897-08-24 | Mechanism | ||
US3097141A (en) | 1959-02-26 | 1963-07-09 | Kidwell Elizabeth N Wilcox | Immunological method |
SE337223B (da) | 1967-05-23 | 1971-08-02 | Pharmacia Ab | |
US3720760A (en) | 1968-09-06 | 1973-03-13 | Pharmacia Ab | Method for determining the presence of reagin-immunoglobulins(reagin-ig)directed against certain allergens,in aqueous samples |
US4171299A (en) | 1975-04-04 | 1979-10-16 | The Regents Of The University Of California | Polypeptide agents for blocking the human allergic response |
US4352883A (en) | 1979-03-28 | 1982-10-05 | Damon Corporation | Encapsulation of biological material |
US4469677A (en) | 1980-02-19 | 1984-09-04 | Michael J Gabriel | Polypeptide active immunosuppressant fraction |
US4338297A (en) | 1980-02-19 | 1982-07-06 | Michael Jacob G | Polypeptide active pollen immunosuppressant fraction |
AR231590A1 (es) | 1981-04-29 | 1984-12-28 | Ciba Geigy Ag | Dispositivo de analisis inmunologico y procedimiento para obtenerlo |
US4888170A (en) | 1981-10-22 | 1989-12-19 | Research Corporation | Vaccines obtained from antigenic gene products of recombinant genes |
CA1338705C (en) * | 1981-10-22 | 1996-11-12 | Roy Curtiss Iii | Vaccines obtained from antigenic gene products of recombinant genes |
US4659678A (en) | 1982-09-29 | 1987-04-21 | Serono Diagnostics Limited | Immunoassay of antigens |
SE8205908D0 (sv) | 1982-10-18 | 1982-10-18 | Pharmacia Diagnostics Ab | Sett att bilda polymerskikt |
US4849337A (en) | 1983-01-31 | 1989-07-18 | Minnesota Mining And Manufacturing Company | Assaying allergen specific IgE levels with fluorogenic enzyme labeled antibody |
CA1260828A (en) | 1983-07-04 | 1989-09-26 | Masakazu Iwai | Therapeutic and prophylactic agent for gastrointestinal ulcers |
US4579840A (en) | 1983-08-12 | 1986-04-01 | Immunetech Pharmaceuticals | Method of blocking immune complex binding to immunoglobulin Fc receptors |
US4816449A (en) | 1984-08-09 | 1989-03-28 | Immunetech Pharmaceuticals | Immunotherapeutic anti-inflammatory peptide agents |
US4680174A (en) | 1984-05-24 | 1987-07-14 | Damon Biotech, Inc. | Induction of immune response by immunization with encapsulated antigen-producing cells |
US4696915A (en) | 1984-05-25 | 1987-09-29 | Hoffmann-La Roche Inc. | Parathymosin alpha |
US5026545A (en) | 1984-09-17 | 1991-06-25 | Baxter International, Inc. | Treatment of allergy and composition therefor |
US4658022A (en) | 1985-08-08 | 1987-04-14 | Molecular Diagnostics, Inc. | Binding of antibody reagents to denatured protein analytes |
US4959314A (en) | 1984-11-09 | 1990-09-25 | Cetus Corporation | Cysteine-depleted muteins of biologically active proteins |
US4900556A (en) | 1985-04-26 | 1990-02-13 | Massachusetts Institute Of Technology | System for delayed and pulsed release of biologically active substances |
US6024983A (en) | 1986-10-24 | 2000-02-15 | Southern Research Institute | Composition for delivering bioactive agents for immune response and its preparation |
IL86583A0 (en) * | 1987-06-04 | 1988-11-15 | Molecular Eng Ass | Vaccine containing a derivative of a microbe and method for the production thereof |
US5843710A (en) | 1987-07-07 | 1998-12-01 | Biotech Australia Pty. Limited And Csiro | Vaccines against animal parasitic nematodes |
US5049390A (en) | 1987-09-02 | 1991-09-17 | Allergy Immuno Technologies, Inc. | Liposome containing immunotherapy agents for treating IgE mediated allergies |
US5449760A (en) | 1987-12-31 | 1995-09-12 | Tanox Biosystems, Inc. | Monoclonal antibodies that bind to soluble IGE but do not bind IGE on IGE expressing B lymphocytes or basophils |
US5169933A (en) | 1988-08-15 | 1992-12-08 | Neorx Corporation | Covalently-linked complexes and methods for enhanced cytotoxicity and imaging |
AT393137B (de) | 1988-10-14 | 1991-08-26 | Biomay Biotech Prod | Verfahren zum screenen einer expressions-cdna- klonbank zur auffindung von polynukleotiden |
US5061790A (en) | 1989-07-10 | 1991-10-29 | Molecular Diagnostics, Inc. | Oxidative denaturation of protein analytes |
JP2787162B2 (ja) | 1989-08-24 | 1998-08-13 | フマキラー株式会社 | 精製ダニアレルゲン |
US5834246A (en) * | 1989-09-18 | 1998-11-10 | Vitec Aktiebolag | Recombinant systems for expression of cholera B-subunit with the aid of foreign promoters and/or leader peptides |
US5328991A (en) | 1989-11-03 | 1994-07-12 | Immulogic Pharmaceutical Corp. | Preparation of alkali-modified cat dander allergen (Fel d I) for immunotherapeutic purposes |
ATE216401T1 (de) | 1989-11-03 | 2002-05-15 | Immulogic Pharma Corp | Aus hausstaub isoliertes t-zellreaktives katzenprotein, und dessen verwendungen |
US6019972A (en) | 1989-11-03 | 2000-02-01 | Immulogic Pharmaceutical Corporation | Peptides of human T cell reactive feline protein (TRFP) |
US5547669A (en) | 1989-11-03 | 1996-08-20 | Immulogic Pharma Corp | Recombinant peptides comprising T cell epitopes of the cat allergen, Fel d I |
US5674980A (en) | 1989-12-21 | 1997-10-07 | Biogen Inc | Fusion protein comprising tat-derived transport moiety |
US5804604A (en) | 1989-12-21 | 1998-09-08 | Biogen, Inc. | Tat-derived transport polypeptides and fusion proteins |
JP3307636B2 (ja) | 1990-01-31 | 2002-07-24 | ボード オブ リージェンツ オブ ザ ユニバーシティ オブ オクラホマ | 自己免疫疾患のためのアッセイおよび治療 |
US6897287B1 (en) | 1990-01-31 | 2005-05-24 | Oklahoma Medical Research Foundation | Ro/SSA peptide reagents for diagnosis of autoantibodies |
US5084350A (en) | 1990-02-16 | 1992-01-28 | The Royal Institution For The Advance Of Learning (Mcgill University) | Method for encapsulating biologically active material including cells |
US5091318A (en) | 1990-04-13 | 1992-02-25 | Abbott Laboratories | Binding of allergens to a solid phase |
US5888762A (en) | 1990-06-05 | 1999-03-30 | Centre National De La Recherche Scientifique (Cnrs) | Neurotropic growth factors comprising a homeobox peptide |
EP0495052A1 (en) | 1990-08-08 | 1992-07-22 | Biomay Biotechnik Produktions- Und Handelsgesellschaft M.B.H. | Allergens of alder pollen and applications thereof |
AT401180B (de) | 1990-08-13 | 1996-07-25 | Biomay Biotech Prod | Für das baumpollenallergen p14 codierende rekombinante dna-moleküle, daraus hergestellte und abgeleitete polypeptide und deren verwendung |
CA2067182A1 (en) | 1990-08-13 | 1992-02-14 | Rudolf Valenta | Birch pollen allergen p14 for diagnosis and therapy of allergic diseases |
JP3139777B2 (ja) | 1990-08-27 | 2001-03-05 | フマキラー株式会社 | 組換えダニアレルゲン |
ES2129410T3 (es) | 1990-09-17 | 1999-06-16 | Mitsui Chemicals Inc | Policarbonato, utilizacion, produccion y purificacion de este compuesto. |
US5599537A (en) | 1990-12-18 | 1997-02-04 | The General Hospital Corporation | Salmonella virulence genes |
US5219990A (en) | 1991-01-28 | 1993-06-15 | Biogen, Inc. | Papillomavirus e2 trans-activation repressors |
US5350835A (en) | 1991-11-05 | 1994-09-27 | Board Of Regents, University Of Texas | Cellular nucleic acid binding protein and uses thereof in regulating gene expression and in the treatment of aids |
JP3156237B2 (ja) | 1991-12-24 | 2001-04-16 | 雪印乳業株式会社 | 抗ヒトIgE モノクローナル抗体 |
WO1993017117A1 (en) * | 1992-02-27 | 1993-09-02 | Lynxvale Limited | Heterologous gene expression in lactococcus, and the expression products therefrom |
US5480972A (en) | 1992-10-30 | 1996-01-02 | The University Of Melbourne | Allergenic proteins from Johnson grass pollen |
ES2095001T5 (es) | 1992-12-22 | 2001-03-16 | Univ Cincinnati | Una composicion terapeutica administrable oralmente y su metodo de obtencion. |
US5558869A (en) | 1992-12-30 | 1996-09-24 | University Of Arkansas | Major peanut allergen ara h II |
AU5957694A (en) | 1992-12-31 | 1994-08-15 | Immulogic Pharmaceutical Corporation | Allergenic proteins and peptides from dog dander and uses therefor |
CA2155648C (en) | 1993-02-12 | 1999-05-11 | Julio M. Fernandez | Condensed-phase microparticle composition and method |
EP0692031B1 (en) | 1993-02-22 | 2007-04-11 | The General Hospital Corporation | Heterologous antigens in live cell vaccine strains |
JP3451572B2 (ja) | 1993-03-04 | 2003-09-29 | アサヒビール株式会社 | 改変したダニ主要アレルゲン及びその製造方法 |
US6849427B1 (en) | 1993-03-12 | 2005-02-01 | Immulogic Pharmaceutical Corp. | Nucleic acids encoding a house dust mite allergen, Der p VII, and uses therefor |
WO1994021675A2 (en) | 1993-03-12 | 1994-09-29 | Immulogic Pharmaceutical Corporation | T cell epitopes of ryegrass pollen allergen |
US5710126A (en) | 1993-03-12 | 1998-01-20 | Immulogic Pharmaceutical Corporation | T cell epitopes of ryegrass pollen allergen |
US5830463A (en) * | 1993-07-07 | 1998-11-03 | University Technology Corporation | Yeast-based delivery vehicles |
US5500161A (en) | 1993-09-21 | 1996-03-19 | Massachusetts Institute Of Technology And Virus Research Institute | Method for making hydrophobic polymeric microparticles |
JP3350794B2 (ja) | 1993-09-29 | 2002-11-25 | アサヒビール株式会社 | 改変したダニ主要アレルゲン |
JP2828391B2 (ja) | 1993-10-29 | 1998-11-25 | 東燃株式会社 | オリゴ糖を表面に有するリポソーム |
US5449669A (en) | 1993-11-10 | 1995-09-12 | The United States Of America As Represented By The Department Of Health And Human Services | IgE-binding epitopes of a major heat-stable crustacean allergen derived from shrimp |
US5731157A (en) | 1993-12-30 | 1998-03-24 | The Procter And Gamble Company | Two-site allergen immunoassay |
US5820862A (en) | 1994-04-14 | 1998-10-13 | Immulogic Pharmaceutical Corporation | T cell epitopes of the major allergens from dermatophagoides (house dust mite) |
JPH07285875A (ja) | 1994-04-19 | 1995-10-31 | Mineo Hayazaki | ノミアレルゲンの製造方法および該方法により製造されるノミアレルゲン |
US5807746A (en) | 1994-06-13 | 1998-09-15 | Vanderbilt University | Method for importing biologically active molecules into cells |
SE9402089D0 (sv) | 1994-06-14 | 1994-06-14 | Rudolf Valenta | Recombinant allergen, fragments thereof, corresponding recombinant DNA molecules, vectors and hosts containing the DNA molecules, diagnostic and therapeutic uses of said allergens and fragments |
US6239116B1 (en) | 1994-07-15 | 2001-05-29 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
US6187311B1 (en) * | 1995-03-28 | 2001-02-13 | Asahi Breweries, Ltd. | Engineered acarid allergen and process for producing the same |
US5840307A (en) | 1995-03-31 | 1998-11-24 | Immulogic Pharmacuetical Corp. | Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation |
US6902743B1 (en) * | 1995-05-22 | 2005-06-07 | The United States Of America As Represented By The Secretary Of The Army | Therapeutic treatment and prevention of infections with a bioactive material(s) encapuslated within a biodegradable-bio-compatable polymeric matrix |
US5820880A (en) | 1995-06-07 | 1998-10-13 | The United States Of America As Represented By The Secretary Of The Army | Liposomal formulation |
US5869040A (en) | 1995-06-07 | 1999-02-09 | Biogen, Inc | Gene therapy methods and compositions |
CA2241918C (en) * | 1995-12-29 | 2008-12-02 | University Of Arkansas | Peanut allergens and methods |
US20030202980A1 (en) * | 1995-12-29 | 2003-10-30 | Caplan Michael J. | Methods and reagents for decreasing clinical reaction to allergy |
US5955593A (en) | 1996-09-09 | 1999-09-21 | Washington University | BH3 interacting domain death agonist |
SE9604815D0 (sv) * | 1996-12-20 | 1996-12-20 | Pharmacia & Upjohn Ab | A metod of diagnosis |
JP2001518781A (ja) * | 1997-03-28 | 2001-10-16 | サイタクラナル、ファーマスーティクス、インク | マイコバクテリウム組換えワクチン |
US5989814A (en) | 1997-04-01 | 1999-11-23 | Reagents Of The University Of California | Screening methods in eucaryotic cells |
US6060082A (en) | 1997-04-18 | 2000-05-09 | Massachusetts Institute Of Technology | Polymerized liposomes targeted to M cells and useful for oral or mucosal drug delivery |
DE69738124T2 (de) | 1997-05-08 | 2008-06-12 | Amarnath Maitra | Verfahren zur Herstellung von hochmonodisperser, Polymeren, hydrophiler Nanopartikel |
DE19729327C1 (de) * | 1997-07-09 | 1998-10-29 | Wieland Electric Gmbh | Schutzleiterklemme |
US5891432A (en) | 1997-07-29 | 1999-04-06 | The Immune Response Corporation | Membrane-bound cytokine compositions comprising GM=CSF and methods of modulating an immune response using same |
US6024961A (en) * | 1997-11-14 | 2000-02-15 | Washington University | Recombinant avirulent immunogenic S typhi having rpos positive phenotype |
DE69940805D1 (de) * | 1998-01-31 | 2009-06-10 | Sinai School Medicine | Verfahren und reagenzien zur verminderung der klinischen reaktion zur allergie |
CA2323929C (en) | 1998-04-03 | 2004-03-09 | University Of Iowa Research Foundation | Methods and products for stimulating the immune system using immunotherapeutic oligonucleotides and cytokines |
US6270723B1 (en) | 1998-06-15 | 2001-08-07 | Bbi Bioseq, Inc. | Rapid cryobaric sterilization and vaccine preparation |
JP2002518458A (ja) * | 1998-06-23 | 2002-06-25 | ザ ボード オブ トラスティーズ オブ ザ リーランド スタンフォード ジュニア ユニバーシティ | アジュバント療法 |
US6004815A (en) * | 1998-08-13 | 1999-12-21 | The Regents Of The University Of California | Bacteria expressing nonsecreted cytolysin as intracellular microbial delivery vehicles to eukaryotic cells |
JP2000210050A (ja) | 1998-11-20 | 2000-08-02 | Asama Kasei Kk | 免疫調節活性分解物およびその製造方法並びにそれを用いた食品 |
WO2000054803A2 (en) * | 1999-03-16 | 2000-09-21 | Panacea Pharmaceuticals, Llc | Immunostimulatory nucleic acids and antigens |
US20050063994A1 (en) * | 2000-04-06 | 2005-03-24 | Caplan Michael J. | Methods and reagents for decreasing clinical reaction to allergy |
US8246945B2 (en) * | 2000-04-06 | 2012-08-21 | University Of Arkansas | Methods and reagents for decreasing clinical reaction to allergy |
WO2001066136A2 (en) * | 2000-04-06 | 2001-09-13 | Panacea Pharmaceuticals, Llc. | Microbial delivery system |
DK1219300T3 (da) | 2000-12-28 | 2007-03-05 | Biomay Prod & Handel | Behandling af allergi |
US7265208B2 (en) | 2001-05-01 | 2007-09-04 | The Regents Of The University Of California | Fusion molecules and treatment of IgE-mediated allergic diseases |
US20050175630A1 (en) * | 2003-12-23 | 2005-08-11 | Eyal Raz | Immunogenic compositions and methods of use thereof |
-
2000
- 2000-12-06 WO PCT/US2000/033121 patent/WO2001066136A2/en active IP Right Grant
- 2000-12-06 EP EP00982485A patent/EP1272213B1/en not_active Expired - Lifetime
- 2000-12-06 DK DK00982485T patent/DK1272213T3/da active
- 2000-12-06 ES ES00982485T patent/ES2260078T3/es not_active Expired - Lifetime
- 2000-12-06 AT AT00982485T patent/ATE319475T1/de active
- 2000-12-06 CA CA2403292A patent/CA2403292C/en not_active Expired - Fee Related
- 2000-12-06 US US09/731,375 patent/US8153414B2/en not_active Expired - Fee Related
- 2000-12-06 JP JP2001564788A patent/JP2004527450A/ja active Pending
- 2000-12-06 AU AU2001219510A patent/AU2001219510B2/en not_active Ceased
- 2000-12-06 AU AU1951001A patent/AU1951001A/xx active Pending
- 2000-12-06 DE DE60026584T patent/DE60026584T2/de not_active Expired - Lifetime
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2003
- 2003-12-04 US US10/728,323 patent/US20040208894A1/en not_active Abandoned
- 2003-12-04 US US10/728,051 patent/US20040234548A1/en not_active Abandoned
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2006
- 2006-06-05 CY CY20061100732T patent/CY1105216T1/el unknown
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2009
- 2009-07-15 JP JP2009166724A patent/JP2009242427A/ja active Pending
-
2010
- 2010-07-26 US US12/843,739 patent/US20110027298A1/en not_active Abandoned
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2012
- 2012-07-10 JP JP2012154555A patent/JP2012207032A/ja active Pending
- 2012-07-19 US US13/553,337 patent/US20130142817A1/en not_active Abandoned
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2013
- 2013-01-16 US US13/742,828 patent/US8815251B2/en not_active Expired - Fee Related
Also Published As
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US8153414B2 (en) | 2012-04-10 |
CY1105216T1 (el) | 2010-03-03 |
AU2001219510B2 (en) | 2007-06-14 |
JP2009242427A (ja) | 2009-10-22 |
US20030035810A1 (en) | 2003-02-20 |
CA2403292A1 (en) | 2001-09-13 |
US20040234548A1 (en) | 2004-11-25 |
US20130243814A1 (en) | 2013-09-19 |
US20040208894A1 (en) | 2004-10-21 |
EP1272213B1 (en) | 2006-03-08 |
US20110027298A1 (en) | 2011-02-03 |
US20130142817A1 (en) | 2013-06-06 |
ATE319475T1 (de) | 2006-03-15 |
WO2001066136A3 (en) | 2001-12-27 |
ES2260078T3 (es) | 2006-11-01 |
DE60026584T2 (de) | 2007-03-08 |
WO2001066136A2 (en) | 2001-09-13 |
JP2012207032A (ja) | 2012-10-25 |
JP2004527450A (ja) | 2004-09-09 |
US8815251B2 (en) | 2014-08-26 |
AU1951001A (en) | 2001-09-17 |
DE60026584D1 (de) | 2006-05-04 |
CA2403292C (en) | 2011-02-08 |
EP1272213A2 (en) | 2003-01-08 |
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