ATE316526T1 - Neue indolylpiperidin-derivate als potente antihistaminische und antiallergische mittel - Google Patents

Neue indolylpiperidin-derivate als potente antihistaminische und antiallergische mittel

Info

Publication number
ATE316526T1
ATE316526T1 AT03755105T AT03755105T ATE316526T1 AT E316526 T1 ATE316526 T1 AT E316526T1 AT 03755105 T AT03755105 T AT 03755105T AT 03755105 T AT03755105 T AT 03755105T AT E316526 T1 ATE316526 T1 AT E316526T1
Authority
AT
Austria
Prior art keywords
potent
anthistaminic
antiallergic agents
new
indolylpiperidine derivatives
Prior art date
Application number
AT03755105T
Other languages
German (de)
English (en)
Inventor
Pou Silvia Fonquerna
Santacana Luis Miguel Pages
Original Assignee
Almirall Prodesfarma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Almirall Prodesfarma Sa filed Critical Almirall Prodesfarma Sa
Application granted granted Critical
Publication of ATE316526T1 publication Critical patent/ATE316526T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
  • Saccharide Compounds (AREA)
AT03755105T 2002-05-29 2003-05-19 Neue indolylpiperidin-derivate als potente antihistaminische und antiallergische mittel ATE316526T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200201226A ES2201907B1 (es) 2002-05-29 2002-05-29 Nuevos derivados de indolilpiperidina como potentes agentes antihistaminicos y antialergicos.

Publications (1)

Publication Number Publication Date
ATE316526T1 true ATE316526T1 (de) 2006-02-15

Family

ID=29558514

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03755105T ATE316526T1 (de) 2002-05-29 2003-05-19 Neue indolylpiperidin-derivate als potente antihistaminische und antiallergische mittel

Country Status (10)

Country Link
US (1) US7560471B2 (enExample)
EP (1) EP1513826B1 (enExample)
JP (1) JP4485353B2 (enExample)
AT (1) ATE316526T1 (enExample)
AU (1) AU2003242544A1 (enExample)
DE (1) DE60303381T2 (enExample)
DK (1) DK1513826T3 (enExample)
ES (2) ES2201907B1 (enExample)
PT (1) PT1513826E (enExample)
WO (1) WO2003099807A1 (enExample)

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JP2013508414A (ja) 2009-10-22 2013-03-07 バーテックス ファーマシューティカルズ インコーポレイテッド 嚢胞性線維症および他の慢性疾患の治療のための組成物
US8247436B2 (en) 2010-03-19 2012-08-21 Novartis Ag Pyridine and pyrazine derivative for the treatment of CF
LT2593452T (lt) 2010-07-14 2017-04-10 Novartis Ag Heterocikliniai junginiai, kaip ip receptoriaus agonistai
WO2012034095A1 (en) 2010-09-09 2012-03-15 Irm Llc Compounds and compositions as trk inhibitors
UY33597A (es) 2010-09-09 2012-04-30 Irm Llc Compuestos y composiciones como inhibidores de la trk
US8372845B2 (en) 2010-09-17 2013-02-12 Novartis Ag Pyrazine derivatives as enac blockers
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EP2678016B1 (en) 2011-02-23 2016-08-10 Intellikine, LLC Heterocyclic compounds and uses thereof
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ES2561353T3 (es) 2012-01-13 2016-02-25 Novartis Ag Sales de un agonista del receptor IP
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MX368059B (es) 2013-07-18 2019-09-18 Novartis Ag Inhibidores de autotaxina que comprenden un núcleo de anillo heteroaromático de bencil-amida cíclica.
TW201605450A (zh) 2013-12-03 2016-02-16 諾華公司 Ｍｄｍ２抑制劑與ＢＲＡＦ抑制劑之組合及其用途
WO2015162558A1 (en) 2014-04-24 2015-10-29 Novartis Ag Autotaxin inhibitors
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BR112016024533A8 (pt) 2014-04-24 2021-03-30 Novartis Ag derivados de amino pirazina como inibidores de fosfatidilinositol 3-cinase ou sal, seu uso, e composição e combinação farmacêuticas
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Also Published As

Publication number Publication date
DE60303381T2 (de) 2006-10-26
US7560471B2 (en) 2009-07-14
JP4485353B2 (ja) 2010-06-23
JP2005527627A (ja) 2005-09-15
AU2003242544A1 (en) 2003-12-12
DE60303381D1 (de) 2006-04-13
DK1513826T3 (da) 2006-06-06
WO2003099807A1 (en) 2003-12-04
EP1513826A1 (en) 2005-03-16
PT1513826E (pt) 2006-05-31
ES2201907B1 (es) 2005-06-01
ES2201907A1 (es) 2004-03-16
ES2254964T3 (es) 2006-06-16
US20060094879A1 (en) 2006-05-04
EP1513826B1 (en) 2006-01-25

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