ATE311406T1 - Hemmstoff und stimulator der proliferation haematopoietischer stammzellen und deren anwendungen - Google Patents

Hemmstoff und stimulator der proliferation haematopoietischer stammzellen und deren anwendungen

Info

Publication number
ATE311406T1
ATE311406T1 AT97920117T AT97920117T ATE311406T1 AT E311406 T1 ATE311406 T1 AT E311406T1 AT 97920117 T AT97920117 T AT 97920117T AT 97920117 T AT97920117 T AT 97920117T AT E311406 T1 ATE311406 T1 AT E311406T1
Authority
AT
Austria
Prior art keywords
proliferation
stimulator
inhibitor
applications
stem cells
Prior art date
Application number
AT97920117T
Other languages
English (en)
Inventor
Stephen D Wolpe
Irena Tsyrlova
Original Assignee
Wellstat Therapeutics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellstat Therapeutics Corp filed Critical Wellstat Therapeutics Corp
Application granted granted Critical
Publication of ATE311406T1 publication Critical patent/ATE311406T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C07K14/805—Haemoglobins; Myoglobins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT97920117T 1996-04-03 1997-04-03 Hemmstoff und stimulator der proliferation haematopoietischer stammzellen und deren anwendungen ATE311406T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/627,173 US5861483A (en) 1996-04-03 1996-04-03 Inhibitor of stem cell proliferation and uses thereof
PCT/US1997/005601 WO1997036922A1 (en) 1996-04-03 1997-04-03 Inhibitor and stimulator of stem cell proliferation and uses thereof

Publications (1)

Publication Number Publication Date
ATE311406T1 true ATE311406T1 (de) 2005-12-15

Family

ID=24513524

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97920117T ATE311406T1 (de) 1996-04-03 1997-04-03 Hemmstoff und stimulator der proliferation haematopoietischer stammzellen und deren anwendungen

Country Status (17)

Country Link
US (4) US5861483A (de)
EP (2) EP0891377B1 (de)
JP (3) JP4241927B2 (de)
KR (1) KR20040088588A (de)
CN (2) CN1264856C (de)
AT (1) ATE311406T1 (de)
AU (1) AU727023B2 (de)
CA (1) CA2249716A1 (de)
DE (1) DE69734766T2 (de)
ES (1) ES2252781T3 (de)
HK (1) HK1069985A1 (de)
IL (2) IL126395A0 (de)
NO (1) NO323610B1 (de)
NZ (1) NZ331895A (de)
RU (1) RU2292352C9 (de)
UA (2) UA74128C2 (de)
WO (1) WO1997036922A1 (de)

Families Citing this family (44)

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UA40613C2 (uk) 1993-03-31 2001-08-15 Про-Нейрон, Інк. Поліпептид, що має активність інгібітора проліферації стовбурових клітин(варіанти), фармацевтична композиція (варіанти), фармацевтична композиція для інгібування ділення стовбурових клітин у ссавців, фармацевтична композиція для лікування захворювань,які включають гіперпроліферативні стани, фармацевтична композиція для диференціального захисту нормальних стовбурових клітин, відмінних від лейкозних, спосіб очистки поліпептиду
US6610654B2 (en) 1993-03-31 2003-08-26 Wellstat Therapeutics Corporation Inhibitor of stem cell proliferation and uses thereof
US5861483A (en) * 1996-04-03 1999-01-19 Pro-Neuron, Inc. Inhibitor of stem cell proliferation and uses thereof
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RU2423375C2 (ru) 2005-07-26 2011-07-10 СиЭмЭс ПЕПТАЙДЗ ПЭЙТЕНТ ХОЛДИНГ КОМПАНИ ЛИМИТЕД Новые биологически активные пептиды и их новое применение
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CN103804484B (zh) * 2014-01-24 2016-03-16 南京必优康生物技术有限公司 一种网红细胞生长因子及其制备方法和应用
CN106317177A (zh) * 2015-06-23 2017-01-11 首都医科大学 Gly-Phe-Pro,其合成,活性和应用
CN107899001B (zh) * 2017-05-16 2021-08-06 陈娟娟 Notch配体蛋白在制备治疗肿瘤化疗导致骨髓抑制药物方面及早期预后判断方面的应用
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Also Published As

Publication number Publication date
CN1174996C (zh) 2004-11-10
RU2292352C9 (ru) 2007-05-10
JP4241927B2 (ja) 2009-03-18
ES2252781T3 (es) 2006-05-16
NZ331895A (en) 2000-07-28
DE69734766D1 (de) 2006-01-05
AU2439197A (en) 1997-10-22
JP2009013178A (ja) 2009-01-22
EP1820805A2 (de) 2007-08-22
KR20040088588A (ko) 2004-10-16
RU2292352C2 (ru) 2007-01-27
NO323610B1 (no) 2007-06-18
JP2000508633A (ja) 2000-07-11
EP0891377A1 (de) 1999-01-20
US5861483A (en) 1999-01-19
HK1069985A1 (en) 2005-06-10
WO1997036922A1 (en) 1997-10-09
CN1220670A (zh) 1999-06-23
UA85036C2 (ru) 2008-12-25
IL126395A0 (en) 1999-05-09
US20060166863A1 (en) 2006-07-27
DE69734766T2 (de) 2006-09-14
EP1820805A3 (de) 2007-11-07
NO984628L (no) 1998-12-01
NO984628D0 (no) 1998-10-02
US20040167060A1 (en) 2004-08-26
IL176642A0 (en) 2006-10-31
UA74128C2 (uk) 2005-11-15
US7115267B2 (en) 2006-10-03
JP2012046537A (ja) 2012-03-08
EP0891377B1 (de) 2005-11-30
EP0891377A4 (de) 2003-01-02
CN1541706A (zh) 2004-11-03
CN1264856C (zh) 2006-07-19
AU727023B2 (en) 2000-11-30
CA2249716A1 (en) 1997-10-09
US6784155B1 (en) 2004-08-31

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