ATE299706T1 - Ionisch vernetzte karboxylgruppe enthaltende polysaccharide zur verhütung von gewebeverklebung - Google Patents

Ionisch vernetzte karboxylgruppe enthaltende polysaccharide zur verhütung von gewebeverklebung

Info

Publication number
ATE299706T1
ATE299706T1 AT92302953T AT92302953T ATE299706T1 AT E299706 T1 ATE299706 T1 AT E299706T1 AT 92302953 T AT92302953 T AT 92302953T AT 92302953 T AT92302953 T AT 92302953T AT E299706 T1 ATE299706 T1 AT E299706T1
Authority
AT
Austria
Prior art keywords
carboxyl group
containing ionic
tissue adhesion
prevent tissue
ionic cross
Prior art date
Application number
AT92302953T
Other languages
English (en)
Inventor
W James Huang
Douglas B Johns
Richard L Kronenthal
Original Assignee
Lifecore Biomedical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lifecore Biomedical Inc filed Critical Lifecore Biomedical Inc
Application granted granted Critical
Publication of ATE299706T1 publication Critical patent/ATE299706T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/717Celluloses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/722Chitin, chitosan
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728Hyaluronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02Local antiseptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AT92302953T 1991-04-05 1992-04-03 Ionisch vernetzte karboxylgruppe enthaltende polysaccharide zur verhütung von gewebeverklebung ATE299706T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US68095591A 1991-04-05 1991-04-05

Publications (1)

Publication Number Publication Date
ATE299706T1 true ATE299706T1 (de) 2005-08-15

Family

ID=24733195

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92302953T ATE299706T1 (de) 1991-04-05 1992-04-03 Ionisch vernetzte karboxylgruppe enthaltende polysaccharide zur verhütung von gewebeverklebung

Country Status (10)

Country Link
US (1) US5532221A (de)
EP (2) EP0507604B1 (de)
JP (1) JP2702641B2 (de)
AT (1) ATE299706T1 (de)
AU (1) AU647905B2 (de)
BR (1) BR9201215A (de)
CA (1) CA2065111C (de)
DE (1) DE69233535T2 (de)
ES (1) ES2246490T3 (de)
GR (1) GR920100122A (de)

Families Citing this family (89)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5610148A (en) * 1991-01-18 1997-03-11 University College London Macroscopically oriented cell adhesion protein for wound treatment
US5629287A (en) * 1991-01-18 1997-05-13 University College London Depot formulations
US5531716A (en) * 1993-09-29 1996-07-02 Hercules Incorporated Medical devices subject to triggered disintegration
US5419775A (en) * 1994-01-18 1995-05-30 Allergan, Inc. Syringe flange adapter and method
ITPD940054A1 (it) * 1994-03-23 1995-09-23 Fidia Advanced Biopolymers Srl Polisaccaridi solfatati
US5690961A (en) 1994-12-22 1997-11-25 Hercules Incorporated Acidic polysaccharides crosslinked with polycarboxylic acids and their uses
DE69635127T2 (de) * 1995-06-06 2006-06-29 C.R. Bard, Inc. Verfahren zur herstellung von vernetzten wasserlöslichen polymerpartikel, die partikel und ihre verwendung
US6214331B1 (en) 1995-06-06 2001-04-10 C. R. Bard, Inc. Process for the preparation of aqueous dispersions of particles of water-soluble polymers and the particles obtained
US5612321A (en) * 1995-06-22 1997-03-18 Hercules Incorporated Antioxidant grafted polysaccharides
JPH11511344A (ja) * 1995-08-29 1999-10-05 フィディア・アドバンスト・バイオポリマーズ・ソシエタ・ア・レスポンサビリタ・リミタータ ヒアルロン酸誘導体からなる術後癒着予防用生体適合材料
SE505873C2 (sv) * 1996-01-10 1997-10-20 Moelnlycke Ab Förfarande för framställning av absorberande material, absorberande material samt absorberande alster innehållande materialet ifråga
US5688923A (en) * 1996-02-15 1997-11-18 Hercules Incorporated Pectin fibers
US5718862A (en) * 1996-04-24 1998-02-17 Hercules Incorporated Secondary shaping of ionically crosslinked polymer compositions for medical devices
US5684051A (en) * 1996-04-24 1997-11-04 Hercules Incorporated Medical devices with improved elastic response
US6368356B1 (en) 1996-07-11 2002-04-09 Scimed Life Systems, Inc. Medical devices comprising hydrogel polymers having improved mechanical properties
US6060534A (en) * 1996-07-11 2000-05-09 Scimed Life Systems, Inc. Medical devices comprising ionically and non-ionically crosslinked polymer hydrogels having improved mechanical properties
US5820918A (en) * 1996-07-11 1998-10-13 Hercules Incorporated Medical devices containing in-situ generated medical compounds
WO1998024477A1 (en) 1996-12-06 1998-06-11 Amgen Inc. Combination therapy using an il-1 inhibitor for treating il-1 mediated diseases
US5789571A (en) * 1997-01-15 1998-08-04 Biocoat Incorporated Method of making free acids from polysaccharide salts
US20050090662A1 (en) * 1997-01-15 2005-04-28 Beavers Ellington M. Method of making free acids from polysaccharide salts
US7192984B2 (en) * 1997-06-17 2007-03-20 Fziomed, Inc. Compositions of polyacids and polyethers and methods for their use as dermal fillers
US20040096422A1 (en) * 1997-06-17 2004-05-20 Schwartz Herbert E. Compositions of polyacids and polyethers and methods for their use in reducing pain
US20050074495A1 (en) * 1997-06-17 2005-04-07 Fziomed, Inc. Compositions of polyacids and methods for their use in reducing adhesions
US6869938B1 (en) 1997-06-17 2005-03-22 Fziomed, Inc. Compositions of polyacids and polyethers and methods for their use in reducing adhesions
US5906997A (en) * 1997-06-17 1999-05-25 Fzio Med, Inc. Bioresorbable compositions of carboxypolysaccharide polyether intermacromolecular complexes and methods for their use in reducing surgical adhesions
JP2002525268A (ja) 1998-09-16 2002-08-13 オンコファーマシューティカル, インコーポレイテッド ゴルジ装置妨害剤の注射可能な処方物での腫瘍学的腫瘍の処置
AU3615700A (en) * 1999-03-04 2000-09-21 United States Surgical Corporation Scar reduction
WO2000054762A2 (en) * 1999-03-15 2000-09-21 Trustees Of Boston University Use of cross linked polysaccharides for the inhibition of angiogenesis
US20040048021A1 (en) * 1999-03-19 2004-03-11 Wan Barbara Y. F. Surface modification of substrates
EP1178851A1 (de) * 1999-03-19 2002-02-13 Genzyme Corporation Oberflächen-modifikation von substraten
US7083777B1 (en) * 1999-04-02 2006-08-01 The Brigham And Women's Hospital, Inc. Immunomodulating polymers
CA2366880C (en) * 1999-04-02 2013-02-12 Fziomed, Inc. Compositions of polyacids and polyethers and methods for their use in reducing adhesions
KR20010010151A (ko) * 1999-07-16 2001-02-05 김윤 수용성 알긴산염과 카르복시메틸 셀룰로오스를 주성분으로 하는 유착방지제 및 그의 제조방법
ES2223583T3 (es) 1999-07-28 2005-03-01 United States Surgical Corporation Barrera antiadherente de acido hialuronico.
US6566345B2 (en) 2000-04-28 2003-05-20 Fziomed, Inc. Polyacid/polyalkylene oxide foams and gels and methods for their delivery
US6638917B1 (en) 2000-02-25 2003-10-28 Scimed Life Systems, Inc. Reducing adhesion
WO2001082863A2 (en) * 2000-04-28 2001-11-08 Fziomed, Inc. Polyacid/polyalkylene oxide foams and gels and methods for their delivery
WO2001093846A2 (en) * 2000-05-23 2001-12-13 The Trustees Of Columbia University In The City Of New York Method for treating respiratory disorders associated with pulmonary elastic fiber injury comprising the use of clycosaminoglycans
US6696483B2 (en) 2000-10-03 2004-02-24 Oncopharmaceutical, Inc. Inhibitors of angiogenesis and tumor growth for local and systemic administration
SV2003000753A (es) 2000-12-05 2003-06-16 Brigham & Womens Hospital Uso de polisacaridos zwitterionicos para la especifica modulacion del progreso inmunologico
US6913765B2 (en) 2001-03-21 2005-07-05 Scimed Life Systems, Inc. Controlling resorption of bioresorbable medical implant material
WO2003002168A1 (en) * 2001-06-29 2003-01-09 Cook Biotech Incorporated Porous sponge matrix medical devices and methods
US7008979B2 (en) * 2002-04-30 2006-03-07 Hydromer, Inc. Coating composition for multiple hydrophilic applications
KR100518152B1 (ko) * 2002-05-09 2005-09-29 메디제네스(주) 혈장 또는 혈청을 함유한 창상 치료용 약학 조성물
US8137688B2 (en) * 2003-01-10 2012-03-20 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
US7465766B2 (en) * 2004-01-08 2008-12-16 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
US8138265B2 (en) * 2003-01-10 2012-03-20 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
US20040167480A1 (en) * 2003-02-21 2004-08-26 Advanced Medical Optics, Inc. Administration of multiple viscoelastic solutions with a multi-compartment syringe
AU2004227852B2 (en) 2003-03-31 2010-01-14 The Brigham And Women's Hospital, Inc. Zwitterionic immunomodulators for the treatment of asthma and allergy
CN100333804C (zh) * 2003-04-18 2007-08-29 上海建华精细生物制品有限公司 透明质酸钠防粘连薄膜及其制备方法
US9066912B2 (en) 2003-11-17 2015-06-30 Ethicon, Inc. Drug-enhanced adhesion prevention
US8524213B2 (en) 2003-12-30 2013-09-03 Genzyme Corporation Polymeric materials, their preparation and use
US8277831B2 (en) * 2004-02-17 2012-10-02 Advanced Technologies And Regenerative Medicine, Llc. Drug-enhanced adhesion prevention
US20060040895A1 (en) * 2004-08-19 2006-02-23 Kipling Thacker Aesthetic use of hyaluronan
US20060142476A1 (en) * 2004-12-29 2006-06-29 Weerawarna S A Crosslinked carboxylated polymer
US20060142561A1 (en) * 2004-12-29 2006-06-29 Mengkui Luo Carboxyalkyl cellulose
US20060142484A1 (en) * 2004-12-29 2006-06-29 Glasser Wolfgang G Sulfoalkylated cellulose polymer network
US20060142478A1 (en) * 2004-12-29 2006-06-29 Mengkui Luo Carboxyalkyl cellulose polymer network
US7541396B2 (en) * 2004-12-29 2009-06-02 Weyerhaeuser Nr Company Method for making carboxyalkyl cellulose
US20060142477A1 (en) * 2004-12-29 2006-06-29 Glasser Wolfgang G Method for making sulfoalkylated cellulose polymer network
US7393905B2 (en) * 2004-12-29 2008-07-01 Weyerhaeuser Company Crosslinked mixed carboxylated polymer network
US7300965B2 (en) 2004-12-29 2007-11-27 Weyerhaeuser Company Mixed polymer network
US7241836B2 (en) * 2004-12-29 2007-07-10 Weyerhaeuser Co. Method of crosslinking a mixture of carboxylated polymers using a triazine crosslinking activator
US20060142481A1 (en) * 2004-12-29 2006-06-29 Herriott Carole W Method for making a mixed polymer network
US7230049B2 (en) * 2004-12-29 2007-06-12 Weyerhaeuser Co. Method of crosslinking a carboxylated polymer using a triazine crosslinking activator
US20060142480A1 (en) * 2004-12-29 2006-06-29 Mengkui Luo Method of making carboxyalkyl cellulose polymer network
CN100415310C (zh) * 2005-03-04 2008-09-03 蒋婧 功能性术后隔离膜及其制备方法
US7323184B2 (en) * 2005-08-22 2008-01-29 Healagenics, Inc. Compositions and methods for the treatment of wounds and the reduction of scar formation
WO2007092451A2 (en) 2006-02-06 2007-08-16 The Brigham And Women's Hospital, Inc. Zwitterionic polysaccharides for promotion of immune system maturation and health
US8114159B2 (en) * 2006-11-20 2012-02-14 Depuy Spine, Inc. Anterior spinal vessel protector
RU2366666C1 (ru) * 2007-12-20 2009-09-10 Институт синтетических полимерных материалов (ИСПМ) им. Н.С. Ениколопова РАН Способ получения сшитых солей гиалуроновой кислоты в водной среде
US8080260B2 (en) * 2008-02-13 2011-12-20 The Cleveland Clinic Foundation Molecular enhancement of extracellular matrix and methods of use
US8668863B2 (en) 2008-02-26 2014-03-11 Board Of Regents, The University Of Texas System Dendritic macroporous hydrogels prepared by crystal templating
EP2300042A4 (de) * 2008-04-30 2012-05-02 Cleveland Clinic Foundation Zusammensetzungen und verfahren zur behandlung von harninkontinenz
KR101062068B1 (ko) * 2008-12-01 2011-09-02 포항공과대학교 산학협력단 유착방지용 조성물
RU2012145811A (ru) 2010-03-29 2014-05-10 Евоник Корпорейшн Композиции и способы улучшенного удержания фармацевтической композиции на участке местного введения
JP6042815B2 (ja) 2010-10-08 2016-12-14 ザ ボード オブ リージェンツ オブ ザ ユニバーシティ オブ テキサス システム 生物医学的応用のためのアルギン酸塩及びヒアルロン酸を用いる抗癒着性バリア膜
WO2012048283A1 (en) 2010-10-08 2012-04-12 Board Of Regents, The University Of Texas System One-step processing of hydrogels for mechanically robust and chemically desired features
EP2731617A4 (de) 2011-07-12 2015-07-01 Brigham & Womens Hospital Lipidhaltige psa-zusammensetzungen, verfahren zu ihrer isolierung und verwendungsverfahren dafür
FR2983483B1 (fr) 2011-12-02 2014-11-14 Vivacy Lab Procede de substitution et reticulation simultanees d'un polysaccharide via ses fonctions hydroxyles
EP2931327B1 (de) 2012-12-11 2019-02-13 Board Of Regents, The University Of Texas System Hydrogelmembran zur anhaftungsverhinderung
US11565027B2 (en) 2012-12-11 2023-01-31 Board Of Regents, The University Of Texas System Hydrogel membrane for adhesion prevention
EP3040367A4 (de) 2013-08-29 2017-04-19 Dainichiseika Color & Chemicals Mfg. Co., Ltd. Verfahren zur herstellung eines wasserunlöslichen formkörpers und wasserunlöslicher formkörper
US10857177B2 (en) 2015-08-19 2020-12-08 President And Fellows Of Harvard College Lipidated PSA compositions and methods
CA2961868A1 (en) * 2016-04-08 2017-10-08 Johnson & Johnson Consumer Inc. Topical compositions containing cross-linked glycosaminoglycans
US11491181B2 (en) 2016-07-15 2022-11-08 President And Fellows Of Harvard College Glycolipid compositions and methods of use
JPWO2018079812A1 (ja) * 2016-10-31 2019-09-19 キユーピー株式会社 ゲル組成物及びその製造方法
WO2018165327A1 (en) 2017-03-08 2018-09-13 Alafair Biosciences, Inc. Hydrogel medium for the storage and preservation of tissue
EP4129349A4 (de) 2020-03-31 2024-03-27 Kureha Corporation Bioabsorbierbares medizinisches material

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4024073A (en) * 1972-01-08 1977-05-17 Toray Industries, Inc. Hydrogel and production thereof
US4141973A (en) * 1975-10-17 1979-02-27 Biotrics, Inc. Ultrapure hyaluronic acid and the use thereof
US4181718A (en) * 1975-12-29 1980-01-01 Mason Norbert S Polyanion-stabilized aluminum hydrogels
JPS5436388A (en) * 1977-08-26 1979-03-17 Sumitomo Electric Ind Ltd Porous polysaccharide and its preparation
CA1140328A (en) * 1979-06-29 1983-02-01 Russell H. Raines Aqueous solutions containing crosslinked hydroxyethyl carboxyethyl cellulose
JPS5844711B2 (ja) * 1979-07-04 1983-10-05 日東電工株式会社 水溶性感圧接着剤組成物
CS211876B1 (cs) * 1980-04-30 1982-02-26 Maxmilian Mozisek Způsob výroby zesíťované karboxymetylcelulózy o vysoké sorpění kapacitě
US4486335A (en) * 1982-08-30 1984-12-04 Hercules Incorporated Carboxymethyl hydroxyethyl cellulose composition
CH666897A5 (fr) * 1983-10-11 1988-08-31 Fidia Spa Fractions d'acide hyaluronique non inflammatoire, procedes et compositions pharmaceutiques.
US4548847A (en) * 1984-01-09 1985-10-22 Kimberly-Clark Corporation Delayed-swelling absorbent systems
SE456346B (sv) * 1984-07-23 1988-09-26 Pharmacia Ab Gel for att forhindra adhesion mellan kroppsvevnader och sett for dess framstellning
US4619995A (en) * 1984-12-24 1986-10-28 Nova Chem Limited N,O-carboxymethyl chitosan and preparative method therefor
SE8501022L (sv) * 1985-03-01 1986-09-02 Pharmacia Ab Format alster och forfarande for dess framstellning
JPH0725663B2 (ja) * 1985-03-11 1995-03-22 大正製薬株式会社 腸溶性軟カプセルの製造方法
IN166447B (de) * 1985-11-27 1990-05-12 Ethicon Inc
CS264719B1 (cs) * 1987-03-06 1989-09-12 Galatik Antonin Farmakologický přípravek na báze derivátu kyseliny hyaluronovej
US4937270A (en) * 1987-09-18 1990-06-26 Genzyme Corporation Water insoluble derivatives of hyaluronic acid
NZ226171A (en) * 1987-09-18 1990-06-26 Ethicon Inc Gel formulation containing polypeptide growth factor
IT1219587B (it) * 1988-05-13 1990-05-18 Fidia Farmaceutici Polisaccaridi carbossiilici autoreticolati
HU203372B (en) * 1989-02-24 1991-07-29 Richter Gedeon Vegyeszet Process for producing hyaluronic associates and pharmaceutical compositions and cosmetics comprising such active ingredient
US5093319A (en) * 1989-10-31 1992-03-03 Pfizer Hospital Products Group, Inc. Use of derivatives of chitin soluble in aqueous solutions for preventing adhesions
DK0426368T3 (da) * 1989-10-31 1995-03-13 Howmedica Præparater indeholdende chitinderivater til forebyggelse af adhæsion
DE4115454A1 (de) * 1991-05-11 1992-11-12 Basf Ag Eisen-(iii)-hyaluronate

Also Published As

Publication number Publication date
AU647905B2 (en) 1994-03-31
EP0507604A2 (de) 1992-10-07
CA2065111C (en) 1999-11-09
EP0507604A3 (en) 1993-10-06
JP2702641B2 (ja) 1998-01-21
CA2065111A1 (en) 1992-10-06
US5532221A (en) 1996-07-02
EP1593394A3 (de) 2007-08-01
DE69233535D1 (de) 2005-08-25
BR9201215A (pt) 1992-12-01
AU1401592A (en) 1992-10-08
ES2246490T3 (es) 2006-02-16
JPH05124968A (ja) 1993-05-21
EP0507604B1 (de) 2005-07-20
GR920100122A (el) 1993-03-16
EP1593394A2 (de) 2005-11-09
DE69233535T2 (de) 2006-04-20

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