ATE257407T1 - Herstellung von peptidhältigen, biologisch abbaubaren mikrokügelchen durch ein schmelzverfahren - Google Patents

Herstellung von peptidhältigen, biologisch abbaubaren mikrokügelchen durch ein schmelzverfahren

Info

Publication number
ATE257407T1
ATE257407T1 AT96937031T AT96937031T ATE257407T1 AT E257407 T1 ATE257407 T1 AT E257407T1 AT 96937031 T AT96937031 T AT 96937031T AT 96937031 T AT96937031 T AT 96937031T AT E257407 T1 ATE257407 T1 AT E257407T1
Authority
AT
Austria
Prior art keywords
microspheres
biodegradable
prepared
drug delivery
microdroplets
Prior art date
Application number
AT96937031T
Other languages
English (en)
Inventor
Younsik Cha
Young Kweon Choi
Chaul Min Pai
Original Assignee
Macromed Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Macromed Inc filed Critical Macromed Inc
Application granted granted Critical
Publication of ATE257407T1 publication Critical patent/ATE257407T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/23—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38—Albumins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D—PROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D7/00—Processes, other than flocking, specially adapted for applying liquids or other fluent materials to particular surfaces or for applying particular liquids or other fluent materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Diabetes (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
AT96937031T 1995-10-25 1996-10-25 Herstellung von peptidhältigen, biologisch abbaubaren mikrokügelchen durch ein schmelzverfahren ATE257407T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/547,962 US5665428A (en) 1995-10-25 1995-10-25 Preparation of peptide containing biodegradable microspheres by melt process
PCT/US1996/017237 WO1997015389A1 (en) 1995-10-25 1996-10-25 Preparation of peptide containing biodegradable microspheres by melt process

Publications (1)

Publication Number Publication Date
ATE257407T1 true ATE257407T1 (de) 2004-01-15

Family

ID=24186865

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96937031T ATE257407T1 (de) 1995-10-25 1996-10-25 Herstellung von peptidhältigen, biologisch abbaubaren mikrokügelchen durch ein schmelzverfahren

Country Status (9)

Country Link
US (1) US5665428A (de)
EP (1) EP0857081B1 (de)
JP (1) JPH11515016A (de)
KR (1) KR100422391B1 (de)
AT (1) ATE257407T1 (de)
AU (1) AU7479796A (de)
CA (1) CA2235602A1 (de)
DE (1) DE69631290D1 (de)
WO (1) WO1997015389A1 (de)

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KR19990067014A (ko) 1999-08-16
KR100422391B1 (ko) 2004-06-12
EP0857081B1 (de) 2004-01-07
EP0857081A4 (de) 1999-03-17
JPH11515016A (ja) 1999-12-21
US5665428A (en) 1997-09-09
AU7479796A (en) 1997-05-15
WO1997015389A1 (en) 1997-05-01
DE69631290D1 (de) 2004-02-12
CA2235602A1 (en) 1997-05-01
EP0857081A1 (de) 1998-08-12

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