KR910007508A - 서방출 드레싱용 제제 및 이의 용도 - Google Patents

서방출 드레싱용 제제 및 이의 용도 Download PDF

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Publication number
KR910007508A
KR910007508A KR1019900016858A KR900016858A KR910007508A KR 910007508 A KR910007508 A KR 910007508A KR 1019900016858 A KR1019900016858 A KR 1019900016858A KR 900016858 A KR900016858 A KR 900016858A KR 910007508 A KR910007508 A KR 910007508A
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South Korea
Prior art keywords
weight
agent
polysiloxane
vehicle
parts
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KR1019900016858A
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English (en)
Inventor
미셀 쟈끄 아귀아디쉬 루시
에티엔느 알랭
Original Assignee
알랭 에프, 조아생
다우 코닝 프랑스 에스. 아.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by 알랭 에프, 조아생, 다우 코닝 프랑스 에스. 아. filed Critical 알랭 에프, 조아생
Publication of KR910007508A publication Critical patent/KR910007508A/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A61K9/2036—Silicones; Polysiloxanes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

내용 없음

Description

서방출 드레싱용 제제 및 이의 용도
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (10)

  1. 약제(A) 및 친수성 성분(a)와 경화성 실리콘 조성물(b)(혼합하여 인간 또는 동물의 신체에 적용한 후 10분 이내에 실온에서 경화되도록 제형화되며 알킬하이드로겐실옥산 단위를 갖는 폴리실록산, 이와의 반응을 위한 불포화 그룸을 갖는 폴리실옥산, 이와의 반응을 위한 불포화 그룹을 갖는 폴리실옥산 하이드로실릴화 반응용 플라티늄 또는 로듐 촉매를 포함한다.)를 포함하는 비이클(B)를 포함함을 특징으로 하는, 인간 또는 동물 신체상또는 신체내의 드레싱으로서 사용하기에 적합한 서방출 제제.
  2. 제1항에 있어서, 분자당2개 이상의 하이드록실 그룹을 갖는 유기물질(Ⅰ)또는 수성 매질에서 팽윤하는 친수성 중합체(Ⅱ)인 조절 성분을 함유함을 특징으로 하는 제제.
  3. 제1항 또는 제2항에 있어서, 친수성 성분(a)이 액체 폴리에틸렌 글리콜, 글리세롤, 소르비를 및 만니톨로 이루어진 그룹중에서 선택되며 분자당2개 이상의 하이드록실 그룹을 갖는 유기 친수성 물질을 함유함을 특징으로 하는 제제.
  4. 제3항에 있어서, 친수성 성분(a)가 글리세롤을 포함하며 비이클의 10내지 30중량%의 함량으로 존재함을 특징으로 하는 제제.
  5. 제2항에 있어서, 유기물질(Ⅰ)이 분자량이 600이상인 고체 폴리에틸렌 글리콜, 소르비톨, 만니톨 및 락토즈로 이루어진 그룹중에서 선택되며 비이클의 5내지 25중량%의 함량으로 존재함을 특징으로 하는 제제.
  6. 제2항에 있어서, 친수성 중합체(Ⅱ)가 하이드록시프로필 셀룰로즈, 카복시메틸 셀룰로즈 및 나트륨 카복시메틸 셀룰로즈(이들은 가교될 수 있고 가교되지 않을 수도 있다)로 이루어진 그룹중에서 선택되며 비이클의 10내지 45중량%의 양으로 존재함을 특징으로 하는 제제.
  7. 제1항 내지 제6항중의 어느 한 항에 있어서, 약제(A)가 항생제, 소독제, 소염제, 심장혈관제, 안티하이드로겐, 기관지확장제, 진통제, 부정맥치료제, 향히스타임제, α-1차단제, β차단제, ACE억제제, 이뇨제, 응집억제제, 진정제, 안정제, 항경련발현제, 응고억제제, 비타민, 웨궤양 및 십이지장궤양 치료제, 단백질 분해효소, 치료인자, 세포 성장 영양제 또는 펩타이드 중에서 선택됨을 특징으로 하는 제제.
  8. 신체상에 또는 이의 인공 또는 천연 공동에 제제를 낳음으로써 즉석에서 경화되어 드레싱으로 부터 신체로 치료제 또는 진단제(A)를 서방출시킬 수 있는 드레싱을 인간 또는 등물 신체내미 또는 신체상에 제공하기 위한 제1항 내지 제8항중의 어느 한 항에 따르는 제제의 용도.
  9. 제1항 있어서, 약제(A) 10내지 70중량부와 비이클(B) 90내지 30중량부[여기서, 비이클(B)는 친수성 성분(a) 10내지 40중량부, 폴리실옥산 40내지 80중량부 및 분자량이 600이상인 폴리에틸렌 글리콜, 소르비톨, 만니톨 및 락토즈로 이루어진 그룹중에서 선택된 친수성 성분(Ⅰ) 10내지 40중량부를 포함한다]를 포함하는, 신체 공동의 투여에 적합한 형태의 제제.
  10. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019900016858A 1989-10-23 1990-10-22 서방출 드레싱용 제제 및 이의 용도 KR910007508A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR898913819A FR2653338B1 (fr) 1989-10-23 1989-10-23 Formulation pour des pansements a liberation prolongee de medicament et son utilisation.
FR8913819 1989-10-23

Publications (1)

Publication Number Publication Date
KR910007508A true KR910007508A (ko) 1991-05-30

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KR1019900016858A KR910007508A (ko) 1989-10-23 1990-10-22 서방출 드레싱용 제제 및 이의 용도

Country Status (13)

Country Link
US (1) US5480653A (ko)
EP (1) EP0465744B1 (ko)
JP (1) JP2997714B2 (ko)
KR (1) KR910007508A (ko)
AU (1) AU635974B2 (ko)
BR (1) BR9005261A (ko)
CA (1) CA2027864C (ko)
DE (1) DE69014614T2 (ko)
DK (1) DK0465744T3 (ko)
FI (1) FI905196A0 (ko)
FR (1) FR2653338B1 (ko)
HU (1) HUT61492A (ko)
IE (1) IE65720B1 (ko)

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Also Published As

Publication number Publication date
FR2653338B1 (fr) 1994-06-10
EP0465744A1 (en) 1992-01-15
US5480653A (en) 1996-01-02
DE69014614D1 (de) 1995-01-12
IE65720B1 (en) 1995-11-15
HU906526D0 (en) 1991-04-29
DE69014614T2 (de) 1995-05-04
JPH03151322A (ja) 1991-06-27
FR2653338A1 (fr) 1991-04-26
BR9005261A (pt) 1991-09-17
AU635974B2 (en) 1993-04-08
HUT61492A (en) 1993-01-28
DK0465744T3 (da) 1995-01-23
CA2027864C (en) 1999-10-12
FI905196A0 (fi) 1990-10-22
JP2997714B2 (ja) 2000-01-11
IE903776A1 (en) 1991-04-24
AU6486490A (en) 1991-04-26
CA2027864A1 (en) 1991-04-24
EP0465744B1 (en) 1994-11-30

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