CA2205564A1 - Pharmaceutical compositions comprising nitric oxide-releasing biopolymers - Google Patents

Pharmaceutical compositions comprising nitric oxide-releasing biopolymers

Info

Publication number
CA2205564A1
CA2205564A1 CA 2205564 CA2205564A CA2205564A1 CA 2205564 A1 CA2205564 A1 CA 2205564A1 CA 2205564 CA2205564 CA 2205564 CA 2205564 A CA2205564 A CA 2205564A CA 2205564 A1 CA2205564 A1 CA 2205564A1
Authority
CA
Canada
Prior art keywords
nitric oxide
pharmaceutical compositions
releasing
releasing biopolymers
polymeric composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA 2205564
Other languages
French (fr)
Other versions
CA2205564C (en
Inventor
Joseph E. Saavedra
Larry K. Keefer
Peter P. Roller
Miki Akamatsu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Department of Health and Human Services
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/344,157 external-priority patent/US5632981A/en
Application filed by Individual filed Critical Individual
Publication of CA2205564A1 publication Critical patent/CA2205564A1/en
Application granted granted Critical
Publication of CA2205564C publication Critical patent/CA2205564C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A polymeric composition capable of releasing nitric oxide under physiological conditions which includes a biopolymer, such as a peptide, polypeptide, protein, oligonucleotide or nucleic acid, to which is bound a nitric oxide-releasing N2O2- functional group;
pharmaceutical compositions comprising the polymeric composition; and method of treating biological disorders in which dosage with nitric oxide is therapeutic.
CA 2205564 1994-11-22 1995-11-20 Pharmaceutical compositions comprising nitric oxide-releasing biopolymers Expired - Fee Related CA2205564C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/344,157 1994-11-22
US08/344,157 US5632981A (en) 1992-08-24 1994-11-22 Biopolymer-bound nitric oxide-releasing compositions, pharmaceutical compositions incorporating same and methods of treating biological disorders using same
PCT/US1995/015180 WO1996015797A1 (en) 1994-11-22 1995-11-20 Pharmaceutical compositions comprising nitric oxide-releasing biopolymers

Publications (2)

Publication Number Publication Date
CA2205564A1 true CA2205564A1 (en) 1996-05-30
CA2205564C CA2205564C (en) 2006-07-11

Family

ID=29405877

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2205564 Expired - Fee Related CA2205564C (en) 1994-11-22 1995-11-20 Pharmaceutical compositions comprising nitric oxide-releasing biopolymers

Country Status (1)

Country Link
CA (1) CA2205564C (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3523367A4 (en) 2016-10-07 2020-06-03 The University Of North Carolina At Chapel Hill S-nitrosothiol-mediated hyperbranched polyesters
CA3048785A1 (en) 2017-01-03 2018-07-12 The University Of North Carolina At Chapel Hill Nitric oxide-releasing alginates as biodegradable antibacterial scaffolds and methods pertaining thereto
WO2018178902A1 (en) 2017-03-28 2018-10-04 The University Of North Carolina At Chapel Hill Nitric oxide-releasing polyaminoglycosides as biodegradable antibacterial scaffolds and methods pertaining thereto
EP3762039A4 (en) 2018-03-06 2021-12-22 The University of North Carolina at Chapel Hill Nitric oxide-releasing cyclodextrins as biodegradable antibacterial scaffolds and methods pertaining thereto
CN113383019B (en) 2018-12-28 2023-11-17 北卡罗来纳大学教堂山分校 Nitric oxide releasing antimicrobial polymers and scaffolds made therefrom and methods relating thereto

Also Published As

Publication number Publication date
CA2205564C (en) 2006-07-11

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Legal Events

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