CA2205564A1 - Pharmaceutical compositions comprising nitric oxide-releasing biopolymers - Google Patents
Pharmaceutical compositions comprising nitric oxide-releasing biopolymersInfo
- Publication number
- CA2205564A1 CA2205564A1 CA 2205564 CA2205564A CA2205564A1 CA 2205564 A1 CA2205564 A1 CA 2205564A1 CA 2205564 CA2205564 CA 2205564 CA 2205564 A CA2205564 A CA 2205564A CA 2205564 A1 CA2205564 A1 CA 2205564A1
- Authority
- CA
- Canada
- Prior art keywords
- nitric oxide
- pharmaceutical compositions
- releasing
- releasing biopolymers
- polymeric composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 title abstract 8
- 229920001222 biopolymer Polymers 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 108091034117 Oligonucleotide Proteins 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 230000004962 physiological condition Effects 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
A polymeric composition capable of releasing nitric oxide under physiological conditions which includes a biopolymer, such as a peptide, polypeptide, protein, oligonucleotide or nucleic acid, to which is bound a nitric oxide-releasing N2O2- functional group;
pharmaceutical compositions comprising the polymeric composition; and method of treating biological disorders in which dosage with nitric oxide is therapeutic.
pharmaceutical compositions comprising the polymeric composition; and method of treating biological disorders in which dosage with nitric oxide is therapeutic.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/344,157 | 1994-11-22 | ||
US08/344,157 US5632981A (en) | 1992-08-24 | 1994-11-22 | Biopolymer-bound nitric oxide-releasing compositions, pharmaceutical compositions incorporating same and methods of treating biological disorders using same |
PCT/US1995/015180 WO1996015797A1 (en) | 1994-11-22 | 1995-11-20 | Pharmaceutical compositions comprising nitric oxide-releasing biopolymers |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2205564A1 true CA2205564A1 (en) | 1996-05-30 |
CA2205564C CA2205564C (en) | 2006-07-11 |
Family
ID=29405877
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA 2205564 Expired - Fee Related CA2205564C (en) | 1994-11-22 | 1995-11-20 | Pharmaceutical compositions comprising nitric oxide-releasing biopolymers |
Country Status (1)
Country | Link |
---|---|
CA (1) | CA2205564C (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3523367A4 (en) | 2016-10-07 | 2020-06-03 | The University Of North Carolina At Chapel Hill | S-nitrosothiol-mediated hyperbranched polyesters |
CA3048785A1 (en) | 2017-01-03 | 2018-07-12 | The University Of North Carolina At Chapel Hill | Nitric oxide-releasing alginates as biodegradable antibacterial scaffolds and methods pertaining thereto |
WO2018178902A1 (en) | 2017-03-28 | 2018-10-04 | The University Of North Carolina At Chapel Hill | Nitric oxide-releasing polyaminoglycosides as biodegradable antibacterial scaffolds and methods pertaining thereto |
EP3762039A4 (en) | 2018-03-06 | 2021-12-22 | The University of North Carolina at Chapel Hill | Nitric oxide-releasing cyclodextrins as biodegradable antibacterial scaffolds and methods pertaining thereto |
CN113383019B (en) | 2018-12-28 | 2023-11-17 | 北卡罗来纳大学教堂山分校 | Nitric oxide releasing antimicrobial polymers and scaffolds made therefrom and methods relating thereto |
-
1995
- 1995-11-20 CA CA 2205564 patent/CA2205564C/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2205564C (en) | 2006-07-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |