ATE256141T1 - N-pyrazol a2a rezeptor agonisten - Google Patents

N-pyrazol a2a rezeptor agonisten

Info

Publication number
ATE256141T1
ATE256141T1 AT00960112T AT00960112T ATE256141T1 AT E256141 T1 ATE256141 T1 AT E256141T1 AT 00960112 T AT00960112 T AT 00960112T AT 00960112 T AT00960112 T AT 00960112T AT E256141 T1 ATE256141 T1 AT E256141T1
Authority
AT
Austria
Prior art keywords
pyrazole
receptor agonists
agonists
receptor
Prior art date
Application number
AT00960112T
Other languages
German (de)
English (en)
Inventor
Jeff A Zablocki
Elfatih O Elzein
Venkata P Palle
Original Assignee
Cv Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cv Therapeutics Inc filed Critical Cv Therapeutics Inc
Application granted granted Critical
Publication of ATE256141T1 publication Critical patent/ATE256141T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT00960112T 1999-06-22 2000-06-21 N-pyrazol a2a rezeptor agonisten ATE256141T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/338,185 US6403567B1 (en) 1999-06-22 1999-06-22 N-pyrazole A2A adenosine receptor agonists
PCT/US2000/040281 WO2000078779A2 (en) 1999-06-22 2000-06-21 N-pyrazole a2a receptor agonists

Publications (1)

Publication Number Publication Date
ATE256141T1 true ATE256141T1 (de) 2003-12-15

Family

ID=23323763

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00960112T ATE256141T1 (de) 1999-06-22 2000-06-21 N-pyrazol a2a rezeptor agonisten

Country Status (27)

Country Link
US (9) US6403567B1 (h)
EP (1) EP1189916B1 (h)
JP (1) JP4727880B2 (h)
KR (1) KR100463300B1 (h)
CN (1) CN1167709C (h)
AR (1) AR024441A1 (h)
AT (1) ATE256141T1 (h)
AU (1) AU760806B2 (h)
BE (1) BE2011C004I2 (h)
BR (1) BRPI0011856B8 (h)
CA (1) CA2377746C (h)
CY (1) CY2011002I2 (h)
DE (2) DE60007127T2 (h)
DK (1) DK1189916T3 (h)
ES (1) ES2209974T3 (h)
FR (1) FR11C0004I2 (h)
HK (1) HK1044952B (h)
IL (2) IL147198A0 (h)
LU (1) LU91785I2 (h)
MX (1) MXPA01013325A (h)
NO (2) NO322457B1 (h)
NZ (1) NZ516334A (h)
PT (1) PT1189916E (h)
TR (1) TR200200588T2 (h)
TW (1) TWI230161B (h)
WO (1) WO2000078779A2 (h)
ZA (1) ZA200200301B (h)

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US7183264B2 (en) 2007-02-27
FR11C0004I1 (fr) 2011-03-11
FR11C0004I2 (fr) 2012-03-16
US20130058866A1 (en) 2013-03-07
WO2000078779A2 (en) 2000-12-28
TWI230161B (en) 2005-04-01
ES2209974T3 (es) 2004-07-01
CY2011002I1 (el) 2012-01-25
AR024441A1 (es) 2002-10-02
US9045519B2 (en) 2015-06-02
US20110144320A1 (en) 2011-06-16
PT1189916E (pt) 2004-03-31
AU760806B2 (en) 2003-05-22
BR0011856B1 (pt) 2014-06-17
US6642210B1 (en) 2003-11-04
TR200200588T2 (tr) 2002-09-23
US7655637B2 (en) 2010-02-02
WO2000078779A3 (en) 2001-03-15
US8278435B2 (en) 2012-10-02
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NO322457B1 (no) 2006-10-09
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CA2377746C (en) 2007-04-10
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US20040038928A1 (en) 2004-02-26
US20140073596A1 (en) 2014-03-13
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US8569260B2 (en) 2013-10-29
IL147198A (en) 2006-04-10
CN1167709C (zh) 2004-09-22
US7144872B2 (en) 2006-12-05
BRPI0011856B8 (pt) 2021-05-25
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