ATE254626T1 - Antibiotische caprazamycine und verfahren zu deren herstellung - Google Patents
Antibiotische caprazamycine und verfahren zu deren herstellungInfo
- Publication number
- ATE254626T1 ATE254626T1 AT00951962T AT00951962T ATE254626T1 AT E254626 T1 ATE254626 T1 AT E254626T1 AT 00951962 T AT00951962 T AT 00951962T AT 00951962 T AT00951962 T AT 00951962T AT E254626 T1 ATE254626 T1 AT E254626T1
- Authority
- AT
- Austria
- Prior art keywords
- caprazamycins
- production
- antibiotic
- bacteria
- antibiotic caprazamycins
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/067—Pyrimidine radicals with ribosyl as the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/16—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing two or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/305—Pyrimidine nucleotides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP22886699 | 1999-08-12 | ||
PCT/JP2000/005415 WO2001012643A1 (fr) | 1999-08-12 | 2000-08-11 | Caprazamycines antibiotiques et leur procede de production |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE254626T1 true ATE254626T1 (de) | 2003-12-15 |
Family
ID=16883115
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00951962T ATE254626T1 (de) | 1999-08-12 | 2000-08-11 | Antibiotische caprazamycine und verfahren zu deren herstellung |
Country Status (10)
Country | Link |
---|---|
US (1) | US6780616B1 (de) |
EP (1) | EP1211259B1 (de) |
JP (1) | JP4521145B2 (de) |
KR (1) | KR100659680B1 (de) |
AT (1) | ATE254626T1 (de) |
AU (1) | AU6475600A (de) |
CA (1) | CA2388050C (de) |
DE (1) | DE60006690T2 (de) |
ES (1) | ES2209942T3 (de) |
WO (1) | WO2001012643A1 (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4759756B2 (ja) * | 2001-07-05 | 2011-08-31 | 公益財団法人微生物化学研究会 | 抗生物質カプラザマイシンd、g、d1、g1とその製造法 |
WO2004046368A1 (ja) * | 2002-11-20 | 2004-06-03 | Sankyo Company, Limited | 新規抗生物質ムラミノミシン(Muraminomicin) |
WO2004057011A1 (ja) * | 2002-12-20 | 2004-07-08 | Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai | 抗生物質カプラザマイシンd、g、d1およびg1とその製造法 |
ES2612856T3 (es) | 2003-01-31 | 2017-05-19 | Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai | Derivado de capraceno para la síntesis de antibióticos |
JP5339840B2 (ja) * | 2008-10-02 | 2013-11-13 | 公益財団法人微生物化学研究会 | 抗xdr−tb薬、抗mdr−tb薬、及び併用抗結核薬 |
JP2012102019A (ja) * | 2009-03-03 | 2012-05-31 | Hokkaido Univ | ヌクレオシド系抗生物質誘導体 |
DE102009014432A1 (de) | 2009-03-26 | 2010-09-30 | Eberhard-Karls-Universität Tübingen | Ein neues Caprazamycin Biosynthesegencluster |
US8754054B2 (en) * | 2010-07-09 | 2014-06-17 | Albany Molecular Research, Inc. | Antibacterial compounds, methods of making them, and uses thereof |
JP5922936B2 (ja) * | 2012-01-25 | 2016-05-24 | 公益財団法人微生物化学研究会 | 新規微生物及びカプラゾールの製造方法 |
JP6326048B2 (ja) * | 2013-06-04 | 2018-05-16 | 公益財団法人微生物化学研究会 | 併用抗抗酸菌薬及びWecA乃至そのオルソログの活性阻害剤 |
US20200246268A1 (en) | 2017-06-08 | 2020-08-06 | Pai Life Sciences Inc. | Cpzen compositions and uses |
MX2020000265A (es) | 2017-07-07 | 2020-07-22 | Epicentrx Inc | Composiciones para la administración parenteral de agentes terapéuticos. |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6098995A (ja) * | 1983-11-04 | 1985-06-01 | Microbial Chem Res Found | 光学活性3−(3,4−ジヒドロキシフエニル)セリン,およびその誘導体の製造法 |
JPH02306992A (ja) * | 1989-05-20 | 1990-12-20 | Rikagaku Kenkyusho | 抗生物質rk―1061g及びrk―1061h並びにその製造法 |
CA2252483A1 (en) * | 1996-04-26 | 1997-11-06 | Snow Brand Milk Products Co., Ltd. | Novel antibiotic rk-1061s and a method of production thereof |
-
2000
- 2000-08-11 KR KR1020027001686A patent/KR100659680B1/ko active IP Right Grant
- 2000-08-11 DE DE60006690T patent/DE60006690T2/de not_active Expired - Lifetime
- 2000-08-11 CA CA002388050A patent/CA2388050C/en not_active Expired - Lifetime
- 2000-08-11 JP JP2001517541A patent/JP4521145B2/ja not_active Expired - Lifetime
- 2000-08-11 WO PCT/JP2000/005415 patent/WO2001012643A1/ja active IP Right Grant
- 2000-08-11 EP EP00951962A patent/EP1211259B1/de not_active Expired - Lifetime
- 2000-08-11 AU AU64756/00A patent/AU6475600A/en not_active Abandoned
- 2000-08-11 ES ES00951962T patent/ES2209942T3/es not_active Expired - Lifetime
- 2000-08-11 US US10/049,970 patent/US6780616B1/en not_active Expired - Lifetime
- 2000-08-11 AT AT00951962T patent/ATE254626T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US6780616B1 (en) | 2004-08-24 |
EP1211259B1 (de) | 2003-11-19 |
KR100659680B1 (ko) | 2006-12-21 |
JP4521145B2 (ja) | 2010-08-11 |
CA2388050C (en) | 2008-03-18 |
WO2001012643A1 (fr) | 2001-02-22 |
EP1211259A1 (de) | 2002-06-05 |
KR20020092899A (ko) | 2002-12-12 |
AU6475600A (en) | 2001-03-13 |
CA2388050A1 (en) | 2001-02-22 |
DE60006690T2 (de) | 2004-09-23 |
ES2209942T3 (es) | 2004-07-01 |
EP1211259A4 (de) | 2002-09-04 |
DE60006690D1 (de) | 2003-12-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |