ATE375343T1 - Neue beta-lactamverbindungen und verfahren zu deren herstellung - Google Patents
Neue beta-lactamverbindungen und verfahren zu deren herstellungInfo
- Publication number
- ATE375343T1 ATE375343T1 AT01979010T AT01979010T ATE375343T1 AT E375343 T1 ATE375343 T1 AT E375343T1 AT 01979010 T AT01979010 T AT 01979010T AT 01979010 T AT01979010 T AT 01979010T AT E375343 T1 ATE375343 T1 AT E375343T1
- Authority
- AT
- Austria
- Prior art keywords
- lower alkyl
- hydrogen
- alkyl
- production
- cyano
- Prior art date
Links
- -1 BETA-LACTAM COMPOUNDS Chemical class 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 150000002431 hydrogen Chemical class 0.000 abstract 3
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- 125000003341 7 membered heterocyclic group Chemical group 0.000 abstract 1
- 241000192125 Firmicutes Species 0.000 abstract 1
- 206010041925 Staphylococcal infections Diseases 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 208000015688 methicillin-resistant staphylococcus aureus infectious disease Diseases 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/20—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/02—Preparation
- C07D477/06—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2000341063 | 2000-11-08 | ||
JP2001126296 | 2001-04-24 | ||
JP2001273615 | 2001-09-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE375343T1 true ATE375343T1 (de) | 2007-10-15 |
Family
ID=27345150
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT01979010T ATE375343T1 (de) | 2000-11-08 | 2001-11-06 | Neue beta-lactamverbindungen und verfahren zu deren herstellung |
Country Status (15)
Country | Link |
---|---|
US (1) | US7163936B2 (de) |
EP (1) | EP1340756B1 (de) |
JP (1) | JP4213958B2 (de) |
KR (1) | KR100814657B1 (de) |
CN (1) | CN100379738C (de) |
AT (1) | ATE375343T1 (de) |
AU (1) | AU2002211006A1 (de) |
CA (1) | CA2427812C (de) |
CY (1) | CY1107837T1 (de) |
DE (1) | DE60130916T2 (de) |
DK (1) | DK1340756T3 (de) |
ES (1) | ES2294035T3 (de) |
PT (1) | PT1340756E (de) |
TW (1) | TWI297689B (de) |
WO (1) | WO2002038564A1 (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9149440B2 (en) * | 2003-09-02 | 2015-10-06 | University Of South Florida | Nanoparticles for drug-delivery |
JP2006008641A (ja) * | 2004-06-29 | 2006-01-12 | Sumitomo Pharmaceut Co Ltd | 光学活性なジヒドロピロールおよびテトラヒドロピリジン誘導体の製造法 |
US20090018111A1 (en) * | 2004-10-08 | 2009-01-15 | Makoto Sunagawa | Novel Antimicrobial Medicament |
WO2007142212A1 (ja) * | 2006-06-08 | 2007-12-13 | Dainippon Sumitomo Pharma Co., Ltd. | 製剤組成物 |
EP2229944A1 (de) | 2007-12-12 | 2010-09-22 | Dainippon Sumitomo Pharma Co., Ltd. | Präparatzusammensetzung |
TW200930722A (en) * | 2007-12-12 | 2009-07-16 | Dainippon Sumitomo Pharma Co | Stable crystal of β-lactam compound |
WO2009093638A1 (ja) * | 2008-01-25 | 2009-07-30 | Dainippon Sumitomo Pharma Co., Ltd. | β-ラクタム化合物の製造方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5750686A (en) * | 1993-06-16 | 1998-05-12 | Sumitomo Pharmaceuticals Company, Limited | Carbapenem compounds and process for producing the same |
JPH1077285A (ja) * | 1996-09-04 | 1998-03-24 | Sumitomo Pharmaceut Co Ltd | 新規なβ−ラクタム化合物およびその製造法 |
JP2000179834A (ja) * | 1998-12-16 | 2000-06-27 | Rinnai Corp | ガスコック装置 |
-
2001
- 2001-11-06 CN CNB018217559A patent/CN100379738C/zh not_active Expired - Fee Related
- 2001-11-06 US US10/416,334 patent/US7163936B2/en not_active Expired - Fee Related
- 2001-11-06 CA CA002427812A patent/CA2427812C/en not_active Expired - Fee Related
- 2001-11-06 WO PCT/JP2001/009664 patent/WO2002038564A1/ja active IP Right Grant
- 2001-11-06 ES ES01979010T patent/ES2294035T3/es not_active Expired - Lifetime
- 2001-11-06 AT AT01979010T patent/ATE375343T1/de active
- 2001-11-06 DE DE60130916T patent/DE60130916T2/de not_active Expired - Lifetime
- 2001-11-06 KR KR1020037006034A patent/KR100814657B1/ko not_active IP Right Cessation
- 2001-11-06 DK DK01979010T patent/DK1340756T3/da active
- 2001-11-06 JP JP2002541097A patent/JP4213958B2/ja not_active Expired - Fee Related
- 2001-11-06 PT PT01979010T patent/PT1340756E/pt unknown
- 2001-11-06 AU AU2002211006A patent/AU2002211006A1/en not_active Abandoned
- 2001-11-06 EP EP01979010A patent/EP1340756B1/de not_active Expired - Lifetime
- 2001-11-07 TW TW090127667A patent/TWI297689B/zh not_active IP Right Cessation
-
2007
- 2007-12-18 CY CY20071101605T patent/CY1107837T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP1340756A1 (de) | 2003-09-03 |
EP1340756A4 (de) | 2004-08-11 |
KR20030048104A (ko) | 2003-06-18 |
CA2427812A1 (en) | 2003-05-02 |
WO2002038564A1 (en) | 2002-05-16 |
DE60130916D1 (de) | 2007-11-22 |
CN100379738C (zh) | 2008-04-09 |
DE60130916T2 (de) | 2008-07-10 |
KR100814657B1 (ko) | 2008-03-18 |
US20040102433A1 (en) | 2004-05-27 |
CA2427812C (en) | 2009-09-29 |
EP1340756B1 (de) | 2007-10-10 |
TWI297689B (en) | 2008-06-11 |
AU2002211006A1 (en) | 2002-05-21 |
ES2294035T3 (es) | 2008-04-01 |
JPWO2002038564A1 (ja) | 2004-03-18 |
JP4213958B2 (ja) | 2009-01-28 |
PT1340756E (pt) | 2008-01-15 |
CY1107837T1 (el) | 2013-06-19 |
US7163936B2 (en) | 2007-01-16 |
CN1484645A (zh) | 2004-03-24 |
DK1340756T3 (da) | 2008-01-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BE2013C004I2 (en) | Phosphonocephem derivatives, process for the preparation of the same, and use thereof | |
MXPA04001323A (es) | Dihidro-3-halo-1h-pirazol-5-carboxilatos sustituidos, su preparacion y uso. | |
ATE368655T1 (de) | Stickstoffhaltige heterocyclische verbindung und arzneimittel davon | |
CA2322171A1 (en) | Cyclic amino compounds | |
WO2008114819A1 (ja) | 新規アデニン化合物 | |
WO2000010965A3 (en) | Quaternary ammonium salts and their use as anti-hiv agents | |
UA83243C2 (ru) | Соединения, которые ингибируют натриезависимый переносчик глюкозы | |
WO2005060972A3 (en) | Pyrrolo [2,3-d] pyrimidine compounds for treating transplant rejection | |
ATE208374T1 (de) | Beta-laktam und cepham verbindungen und ihre herstellung | |
ATE339409T1 (de) | Trizyklische verbindungen | |
EA200100994A1 (ru) | 1-АМИНОТРИАЗОЛО[4,3-а]ХИНАЗОЛИН-5-ОНЫ И/ИЛИ -5-ТИОНЫ, ИНГИБИРУЮЩИЕ ФОСФОДИЭСТЕРАЗУ-IV | |
AU673213B2 (en) | Quinoline or quinazoline derivatives, their production and use | |
EP1364950A4 (de) | Pyridopyrimidin- und naphthyridinderivate | |
CY1107837T1 (el) | Νεες ενωσεις βητα-λακταμης και διαδικασιες για την παραγωγη αυτων | |
CA2273303A1 (en) | Thienylsulfonylamino(thio)carbonyl compounds | |
AU2001292350A1 (en) | Promoters for the proliferation and differentiation of stem cells and/or neuron precursor cells | |
CA2334727A1 (en) | Tetrahydroquinoline derivatives as glycine antagonists | |
ATE219085T1 (de) | 2-beta-substituierte-6-alkylidenpenizillansäure derivate als beta-laktamase inhibitoren | |
WO2003059878A3 (en) | Thieno (3, 2-b) pyridones as antiviral compounds | |
AU2002214325A1 (en) | Process for producing carbapenem-type antibacterial | |
ATE279191T1 (de) | Trizyklische dihydrobenzofurane, verfahren zu deren herstellung und mittel | |
CA2088702A1 (en) | Aminobenzoic acid derivatives | |
EP1227081A4 (de) | Verfahren zur herstellung von oxyiminoalkansäure-derivaten | |
EP0934942A4 (de) | Beta-lactam verbindungen und verfahren zu ihrer herstellung | |
ATE163184T1 (de) | Neue cephalosporinantibiotika und verfahren zu ihrer herstellung |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 1340756 Country of ref document: EP |