ATE279191T1 - Trizyklische dihydrobenzofurane, verfahren zu deren herstellung und mittel - Google Patents
Trizyklische dihydrobenzofurane, verfahren zu deren herstellung und mittelInfo
- Publication number
- ATE279191T1 ATE279191T1 AT00953479T AT00953479T ATE279191T1 AT E279191 T1 ATE279191 T1 AT E279191T1 AT 00953479 T AT00953479 T AT 00953479T AT 00953479 T AT00953479 T AT 00953479T AT E279191 T1 ATE279191 T1 AT E279191T1
- Authority
- AT
- Austria
- Prior art keywords
- ring
- further substituted
- dihydrobenzofuranes
- tricyclic
- production
- Prior art date
Links
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004852 dihydrofuranyl group Chemical group O1C(CC=C1)* 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000003859 lipid peroxidation Effects 0.000 abstract 1
- 229940126707 lipid peroxidation inhibitor Drugs 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP23471899 | 1999-08-20 | ||
| PCT/JP2000/005523 WO2001014384A1 (en) | 1999-08-20 | 2000-08-18 | Tricyclic dihydrobenzofuran derivatives, process for the preparation thereof and agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE279191T1 true ATE279191T1 (de) | 2004-10-15 |
Family
ID=16975297
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00953479T ATE279191T1 (de) | 1999-08-20 | 2000-08-18 | Trizyklische dihydrobenzofurane, verfahren zu deren herstellung und mittel |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6872718B1 (de) |
| EP (1) | EP1211253B1 (de) |
| AT (1) | ATE279191T1 (de) |
| AU (1) | AU6594900A (de) |
| CA (1) | CA2382413A1 (de) |
| DE (1) | DE60014936T2 (de) |
| WO (1) | WO2001014384A1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60019619T2 (de) | 1999-08-20 | 2006-03-02 | Takeda Chemical Industries, Ltd. | Dihydrobenzofuranderivate, verfahren zu ihrer herstellung und mittel |
| US7435837B2 (en) | 2003-10-24 | 2008-10-14 | Wyeth | Dihydrobenzofuranyl alkanamine derivatives and methods for using same |
| US7728155B2 (en) | 2003-10-24 | 2010-06-01 | Wyeth Llc | Dihydrobenzofuranyl alkanamines and methods for using same as cns agents |
| CN100448861C (zh) * | 2003-10-24 | 2009-01-07 | 惠氏公司 | 二氢苯并呋喃烷胺和含有它们的药物组合物 |
| US20070043100A1 (en) | 2005-08-16 | 2007-02-22 | Hagen Eric J | Novel polymorphs of azabicyclohexane |
| US20080045725A1 (en) | 2006-04-28 | 2008-02-21 | Murry Jerry A | Process For The Synthesis of (+) And (-)-1-(3,4-Dichlorophenyl)-3-Azabicyclo[3.1.0]Hexane |
| JP5710277B2 (ja) * | 2008-03-05 | 2015-04-30 | エジソン ファーマシューティカルズ， インコーポレイテッド | 酸化ストレス疾患の処置のための２−置換−ｐ−キノン誘導体 |
| KR20120089259A (ko) | 2009-08-03 | 2012-08-09 | 유니버시티 오브 마이애미 | Ｔ 조절 세포의 생체 내 확장 방법 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2030899A1 (de) | 1970-06-18 | 1971-12-23 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Chinolincarbonsäurederivate |
| US4008237A (en) | 1972-07-14 | 1977-02-15 | Sumitomo Chemical Company, Limited | 2,3,5,8-Tetrahydro-5-alkoxy-8-oxofuro(2,3-g)quinoline-7-carboxylic acid derivatives |
| JPS50117909A (de) | 1974-02-27 | 1975-09-16 | ||
| JPS50117908A (de) | 1974-02-27 | 1975-09-16 | ||
| GB1556747A (en) | 1976-07-05 | 1979-11-28 | Schering Ag | 8-oxo-2 3 5 8-tetrahydrofuro 2 3-g quincline-7- carboxylicacid derivatives |
| JP2855340B2 (ja) | 1988-06-10 | 1999-02-10 | 武田薬品工業株式会社 | ２―置換クマラン誘導体 |
| US5420289A (en) | 1989-10-27 | 1995-05-30 | American Home Products Corporation | Substituted indole-, indene-, pyranoindole- and tetrahydrocarbazole-alkanoic acid derivatives as inhibitors of PLA2 and lipoxygenase |
| TW199152B (de) | 1990-11-01 | 1993-02-01 | Takeda Pharm Industry Co Ltd | |
| JP3153335B2 (ja) * | 1992-06-05 | 2001-04-09 | 興和株式会社 | キノリン誘導体又はその塩 |
| WO1995029177A1 (en) * | 1994-04-23 | 1995-11-02 | Smithkline Beecham P.L.C. | Tricyclic derivatives as 5ht2c and 5ht2b antagonists |
| US5972935A (en) * | 1995-08-11 | 1999-10-26 | Smithkline Beecham P.L.C. | Biphenyl(thio)amide and bipennylethan(thi) one derivatives, their preparation and their use as 5-HT1D receptor antagonists |
| US6147089A (en) | 1998-09-17 | 2000-11-14 | Pfizer Inc. | Annulated 4-carboxyamino-2-methyl-1,2,3,4,-tetrahydroquinolines |
-
2000
- 2000-08-18 AT AT00953479T patent/ATE279191T1/de not_active IP Right Cessation
- 2000-08-18 AU AU65949/00A patent/AU6594900A/en not_active Abandoned
- 2000-08-18 WO PCT/JP2000/005523 patent/WO2001014384A1/ja not_active Ceased
- 2000-08-18 EP EP00953479A patent/EP1211253B1/de not_active Expired - Lifetime
- 2000-08-18 US US10/069,180 patent/US6872718B1/en not_active Expired - Fee Related
- 2000-08-18 DE DE60014936T patent/DE60014936T2/de not_active Expired - Lifetime
- 2000-08-18 CA CA002382413A patent/CA2382413A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU6594900A (en) | 2001-03-19 |
| US6872718B1 (en) | 2005-03-29 |
| EP1211253B1 (de) | 2004-10-13 |
| WO2001014384A1 (en) | 2001-03-01 |
| EP1211253A1 (de) | 2002-06-05 |
| CA2382413A1 (en) | 2001-03-01 |
| DE60014936T2 (de) | 2005-10-13 |
| DE60014936D1 (de) | 2004-11-18 |
| EP1211253A4 (de) | 2003-03-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |