ATE279191T1 - Trizyklische dihydrobenzofurane, verfahren zu deren herstellung und mittel - Google Patents

Trizyklische dihydrobenzofurane, verfahren zu deren herstellung und mittel

Info

Publication number
ATE279191T1
ATE279191T1 AT00953479T AT00953479T ATE279191T1 AT E279191 T1 ATE279191 T1 AT E279191T1 AT 00953479 T AT00953479 T AT 00953479T AT 00953479 T AT00953479 T AT 00953479T AT E279191 T1 ATE279191 T1 AT E279191T1
Authority
AT
Austria
Prior art keywords
ring
further substituted
dihydrobenzofuranes
tricyclic
production
Prior art date
Application number
AT00953479T
Other languages
English (en)
Inventor
Shigenori Ohkawa
Tadatoshi Hashimoto
Tetsuya Tsukamoto
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of ATE279191T1 publication Critical patent/ATE279191T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT00953479T 1999-08-20 2000-08-18 Trizyklische dihydrobenzofurane, verfahren zu deren herstellung und mittel ATE279191T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP23471899 1999-08-20
PCT/JP2000/005523 WO2001014384A1 (fr) 1999-08-20 2000-08-18 Derives dihydrobenzofuran tricycliques, leur procede de preparation et agents

Publications (1)

Publication Number Publication Date
ATE279191T1 true ATE279191T1 (de) 2004-10-15

Family

ID=16975297

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00953479T ATE279191T1 (de) 1999-08-20 2000-08-18 Trizyklische dihydrobenzofurane, verfahren zu deren herstellung und mittel

Country Status (7)

Country Link
US (1) US6872718B1 (de)
EP (1) EP1211253B1 (de)
AT (1) ATE279191T1 (de)
AU (1) AU6594900A (de)
CA (1) CA2382413A1 (de)
DE (1) DE60014936T2 (de)
WO (1) WO2001014384A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7008940B1 (en) 1999-08-20 2006-03-07 Takeda Pharmaceutical Company Limited Dihydrobenzofuran derivatives, process for the preparing thereof and agents
US7435837B2 (en) 2003-10-24 2008-10-14 Wyeth Dihydrobenzofuranyl alkanamine derivatives and methods for using same
CN100448861C (zh) * 2003-10-24 2009-01-07 惠氏公司 二氢苯并呋喃烷胺和含有它们的药物组合物
US7728155B2 (en) 2003-10-24 2010-06-01 Wyeth Llc Dihydrobenzofuranyl alkanamines and methods for using same as cns agents
US20070043100A1 (en) 2005-08-16 2007-02-22 Hagen Eric J Novel polymorphs of azabicyclohexane
US20080045725A1 (en) * 2006-04-28 2008-02-21 Murry Jerry A Process For The Synthesis of (+) And (-)-1-(3,4-Dichlorophenyl)-3-Azabicyclo[3.1.0]Hexane
CA2717734A1 (en) 2008-03-05 2009-09-11 Edison Pharmaceuticals, Inc 2-substituted-p-quinone derivatives for treatment of oxidative stress diseases
ES2586837T3 (es) 2009-08-03 2016-10-19 University Of Miami Método para la expansión in vivo de linfocitos T reguladores

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2030899A1 (de) 1970-06-18 1971-12-23 Schering Ag, 1000 Berlin Und 4619 Bergkamen Chinolincarbonsäurederivate
US4008237A (en) 1972-07-14 1977-02-15 Sumitomo Chemical Company, Limited 2,3,5,8-Tetrahydro-5-alkoxy-8-oxofuro(2,3-g)quinoline-7-carboxylic acid derivatives
JPS50117909A (de) 1974-02-27 1975-09-16
JPS50117908A (de) 1974-02-27 1975-09-16
GB1556747A (en) 1976-07-05 1979-11-28 Schering Ag 8-oxo-2 3 5 8-tetrahydrofuro 2 3-g quincline-7- carboxylicacid derivatives
JP2855340B2 (ja) 1988-06-10 1999-02-10 武田薬品工業株式会社 ２―置換クマラン誘導体
US5420289A (en) 1989-10-27 1995-05-30 American Home Products Corporation Substituted indole-, indene-, pyranoindole- and tetrahydrocarbazole-alkanoic acid derivatives as inhibitors of PLA2 and lipoxygenase
TW199152B (de) * 1990-11-01 1993-02-01 Takeda Pharm Industry Co Ltd
JP3153335B2 (ja) * 1992-06-05 2001-04-09 興和株式会社 キノリン誘導体又はその塩
EP0757687A1 (de) * 1994-04-23 1997-02-12 Smithkline Beecham Plc Tricyclische derivate als 5ht2c und 5ht2b antagonisten
WO1997007120A1 (en) * 1995-08-11 1997-02-27 Smithkline Beecham Plc Biphenyl(thio)amide and biphenylethan(thi)one derivatives, their preparation and their use as 5-ht1d receptor antagonists
US6147089A (en) * 1998-09-17 2000-11-14 Pfizer Inc. Annulated 4-carboxyamino-2-methyl-1,2,3,4,-tetrahydroquinolines

Also Published As

Publication number Publication date
DE60014936D1 (de) 2004-11-18
EP1211253A4 (de) 2003-03-26
CA2382413A1 (en) 2001-03-01
EP1211253B1 (de) 2004-10-13
EP1211253A1 (de) 2002-06-05
DE60014936T2 (de) 2005-10-13
US6872718B1 (en) 2005-03-29
AU6594900A (en) 2001-03-19
WO2001014384A1 (fr) 2001-03-01

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties