ATE84787T1 - Prolin-derivate. - Google Patents

Prolin-derivate.

Info

Publication number
ATE84787T1
ATE84787T1 AT87118566T AT87118566T ATE84787T1 AT E84787 T1 ATE84787 T1 AT E84787T1 AT 87118566 T AT87118566 T AT 87118566T AT 87118566 T AT87118566 T AT 87118566T AT E84787 T1 ATE84787 T1 AT E84787T1
Authority
AT
Austria
Prior art keywords
group
chem
general formula
carbon atoms
alkyl
Prior art date
Application number
AT87118566T
Other languages
English (en)
Inventor
Masaaki Toda
Shuichi Shinbayashida Ohuchida
Hiroyuki Ohno
Original Assignee
Ono Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co filed Critical Ono Pharmaceutical Co
Application granted granted Critical
Publication of ATE84787T1 publication Critical patent/ATE84787T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT87118566T 1986-12-29 1987-12-15 Prolin-derivate. ATE84787T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP31015186 1986-12-29
EP87118566A EP0275482B1 (de) 1986-12-29 1987-12-15 Prolin-Derivate

Publications (1)

Publication Number Publication Date
ATE84787T1 true ATE84787T1 (de) 1993-02-15

Family

ID=18001775

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87118566T ATE84787T1 (de) 1986-12-29 1987-12-15 Prolin-derivate.

Country Status (6)

Country Link
US (2) US4983624A (de)
EP (1) EP0275482B1 (de)
KR (1) KR950009359B1 (de)
AT (1) ATE84787T1 (de)
DE (1) DE3783754T2 (de)
ES (1) ES2046195T3 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3879522T2 (de) * 1987-02-04 1993-09-02 Ono Pharmaceutical Co Prolinalderivate.
US5212191A (en) * 1988-04-08 1993-05-18 Ono Pharmaceutical Co., Ltd. Heterocyclic compounds
WO1990012005A1 (fr) * 1989-04-13 1990-10-18 Japan Tobacco Inc. Nouveaux derives aminoacides possedant une activite d'inhibiteur de la prolylendopeptidase
JP4806628B2 (ja) 2003-05-05 2011-11-02 プロビオドルグ エージー グルタミニルシクラーゼ阻害剤
WO2005049027A2 (en) 2003-11-03 2005-06-02 Probiodrug Ag Combinations useful for the treatment of neuronal disorders
KR101099206B1 (ko) 2004-02-05 2011-12-27 프로비오드룩 아게 신규한 글루타미닐 시클라제 저해제
US8278345B2 (en) 2006-11-09 2012-10-02 Probiodrug Ag Inhibitors of glutaminyl cyclase
JP5523107B2 (ja) 2006-11-30 2014-06-18 プロビオドルグ エージー グルタミニルシクラーゼの新規阻害剤
EP2481408A3 (de) 2007-03-01 2013-01-09 Probiodrug AG Neue Verwendung von Inhibitoren der Glutaminyl Cyclase
WO2008128985A1 (en) 2007-04-18 2008-10-30 Probiodrug Ag Thiourea derivatives as glutaminyl cyclase inhibitors
WO2008144748A1 (en) * 2007-05-21 2008-11-27 The Uab Research Foundation Prolyl endopeptidase inhibitors for reducing or preventing neutrophilic inflammation
MX2012002993A (es) 2009-09-11 2012-04-19 Probiodrug Ag Derivados heterociclicos como inhibidores de ciclasa glutaminilo.
JP6026284B2 (ja) 2010-03-03 2016-11-16 プロビオドルグ エージー グルタミニルシクラーゼの阻害剤
US8269019B2 (en) 2010-03-10 2012-09-18 Probiodrug Ag Inhibitors
WO2011131748A2 (en) 2010-04-21 2011-10-27 Probiodrug Ag Novel inhibitors
ES2570167T3 (es) 2011-03-16 2016-05-17 Probiodrug Ag Derivados de benzimidazol como inhibidores de glutaminil ciclasa
PL3461819T3 (pl) 2017-09-29 2020-11-30 Probiodrug Ag Inhibitory cyklazy glutaminylowej

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6137764A (ja) * 1984-07-31 1986-02-22 Suntory Ltd 抗プロリルエンドペプチダ−ゼ活性を有する新規生理活性化合物
US4772587A (en) * 1985-04-16 1988-09-20 Suntory Limited Dipeptide derivative of fatty acid
JPH0623190B2 (ja) * 1985-04-16 1994-03-30 サントリー株式会社 インヒビタ−活性を有するｎ−アシルピロリジン誘導体及びその製法並びに用途
EP0268190B1 (de) * 1986-11-20 1993-06-16 Ono Pharmaceutical Co., Ltd. Prolinalderivate

Also Published As

Publication number Publication date
DE3783754T2 (de) 1993-08-05
KR880007457A (ko) 1988-08-27
EP0275482B1 (de) 1993-01-20
EP0275482A2 (de) 1988-07-27
ES2046195T3 (es) 1994-02-01
US5112847A (en) 1992-05-12
DE3783754D1 (de) 1993-03-04
KR950009359B1 (ko) 1995-08-21
US4983624A (en) 1991-01-08
EP0275482A3 (en) 1988-12-28

Similar Documents

Publication Publication Date Title
DE3879522D1 (de) Prolinalderivate.
ES2103287T3 (es) Nuevos derivados de tiazolidina.
DE3783754D1 (de) Prolin-derivate.
AU698486B2 (en) Piperazine derivatives
LU91196I2 (fr) Picoxystrobin et ses dérivlés pharmaceutiquement acceptables(ACANTO).
ES2070135T3 (es) Derivados de pirrolidina anti-amnesicos.
DE68918681D1 (de) Glycosidasehemmer.
ATE123778T1 (de) Beta-lactam-derivate.
MX9604398A (es) Derivados de sulfonamida.
ATE71619T1 (de) Pyridazinon-derivate.
AR245699A1 (es) Compuestos derivados de n'-alquil-n,n'-diacilhidrazinas insecticidamente activos y composicion que los comprende.
DK0623131T3 (da) Alkylderivater af trazodon med CNS-aktivitet
HUT45373A (en) Herbicides containing as active substance derivatives of 1-carbamoil-2-pinasoline and process for production of the active substances
DE69734479D1 (de) Herstellung von Thiazolen
ES2077697T3 (es) Derivados de 1-fenoxicarbonil-2-pirrolidinona y agentes nootropicos.
GB2299334A (en) Metalloproteinase inhibitors
CA2359031A1 (en) Thiazolidinone or oxazolidinone derivatives for treatment of ulcerative disease

Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee