ATE295852T1 - Antibiotische tripropeptine und verfahren ihrer herstellung - Google Patents
Antibiotische tripropeptine und verfahren ihrer herstellungInfo
- Publication number
- ATE295852T1 ATE295852T1 AT01917554T AT01917554T ATE295852T1 AT E295852 T1 ATE295852 T1 AT E295852T1 AT 01917554 T AT01917554 T AT 01917554T AT 01917554 T AT01917554 T AT 01917554T AT E295852 T1 ATE295852 T1 AT E295852T1
- Authority
- AT
- Austria
- Prior art keywords
- tripropeptin
- methyl
- group
- resistant strains
- tripropeptins
- Prior art date
Links
- 230000003115 biocidal effect Effects 0.000 title abstract 2
- -1 7-methyl-octyl group Chemical group 0.000 abstract 5
- 241000894006 Bacteria Species 0.000 abstract 2
- 239000003242 anti bacterial agent Substances 0.000 abstract 2
- 230000000844 anti-bacterial effect Effects 0.000 abstract 2
- 241001248650 Lysobacter sp. Species 0.000 abstract 1
- RJQXTJLFIWVMTO-TYNCELHUSA-N Methicillin Chemical compound COC1=CC=CC(OC)=C1C(=O)N[C@@H]1C(=O)N2[C@@H](C(O)=O)C(C)(C)S[C@@H]21 RJQXTJLFIWVMTO-TYNCELHUSA-N 0.000 abstract 1
- 108010059993 Vancomycin Proteins 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 229960003085 meticillin Drugs 0.000 abstract 1
- 108010091003 tripropeptin C Proteins 0.000 abstract 1
- ZJFQULWBEYLWOH-UHFFFAOYSA-N tripropeptin a Chemical compound O=C1NC(C(O)C(O)=O)C(=O)OC(CCCCCCCC(C)C)CC(=O)NC(C(C)O)C(=O)N2CCCC2C(=O)N2CCCC2C(=O)NC(CCCNC(N)=N)C(=O)NC(C(O)C(O)=O)C(=O)NC(CO)C(=O)N2CCC(O)C21 ZJFQULWBEYLWOH-UHFFFAOYSA-N 0.000 abstract 1
- HDRXFYLSJDHVBY-UHFFFAOYSA-N tripropeptin b Chemical compound O=C1NC(C(O)C(O)=O)C(=O)OC(CCCCCCCCC(C)C)CC(=O)NC(C(C)O)C(=O)N2CCCC2C(=O)N2CCCC2C(=O)NC(CCCNC(N)=N)C(=O)NC(C(O)C(O)=O)C(=O)NC(CO)C(=O)N2CCC(O)C21 HDRXFYLSJDHVBY-UHFFFAOYSA-N 0.000 abstract 1
- ZRHHHIZQDIARCA-UHFFFAOYSA-N tripropeptin c Chemical compound O=C1NC(C(O)C(O)=O)C(=O)OC(CCCCCCCCCC(C)C)CC(=O)NC(C(C)O)C(=O)N2CCCC2C(=O)N2CCCC2C(=O)NC(CCCNC(N)=N)C(=O)NC(C(O)C(O)=O)C(=O)NC(CO)C(=O)N2CCC(O)C21 ZRHHHIZQDIARCA-UHFFFAOYSA-N 0.000 abstract 1
- DETFTHHTKCLOGR-UHFFFAOYSA-N tripropeptin d Chemical compound O=C1NC(C(O)C(O)=O)C(=O)OC(CCCCCCCCCCC(C)C)CC(=O)NC(C(C)O)C(=O)N2CCCC2C(=O)N2CCCC2C(=O)NC(CCCNC(N)=N)C(=O)NC(C(O)C(O)=O)C(=O)NC(CO)C(=O)N2CCC(O)C21 DETFTHHTKCLOGR-UHFFFAOYSA-N 0.000 abstract 1
- CDGPSUVNLUGBRV-UHFFFAOYSA-N tripropeptin z Chemical compound O=C1NC(C(O)C(O)=O)C(=O)OC(CCCCCCC(C)C)CC(=O)NC(C(C)O)C(=O)N2CCCC2C(=O)N2CCCC2C(=O)NC(CCCNC(N)=N)C(=O)NC(C(O)C(O)=O)C(=O)NC(CO)C(=O)N2CCC(O)C21 CDGPSUVNLUGBRV-UHFFFAOYSA-N 0.000 abstract 1
- 229960003165 vancomycin Drugs 0.000 abstract 1
- MYPYJXKWCTUITO-LYRMYLQWSA-N vancomycin Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C2C=C3C=C1OC1=CC=C(C=C1Cl)[C@@H](O)[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]1C(=O)N[C@H](C(N[C@@H](C3=CC(O)=CC(O)=C3C=3C(O)=CC=C1C=3)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)O2)=O)NC(=O)[C@@H](CC(C)C)NC)[C@H]1C[C@](C)(N)[C@H](O)[C@H](C)O1 MYPYJXKWCTUITO-LYRMYLQWSA-N 0.000 abstract 1
- MYPYJXKWCTUITO-UHFFFAOYSA-N vancomycin Natural products O1C(C(=C2)Cl)=CC=C2C(O)C(C(NC(C2=CC(O)=CC(O)=C2C=2C(O)=CC=C3C=2)C(O)=O)=O)NC(=O)C3NC(=O)C2NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(CC(C)C)NC)C(O)C(C=C3Cl)=CC=C3OC3=CC2=CC1=C3OC1OC(CO)C(O)C(O)C1OC1CC(C)(N)C(O)C(C)O1 MYPYJXKWCTUITO-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K11/02—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof cyclic, e.g. valinomycins ; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Compounds Of Unknown Constitution (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000093405 | 2000-03-30 | ||
| PCT/JP2001/002578 WO2001074850A1 (fr) | 2000-03-30 | 2001-03-28 | Antibiotiques tripropeptines et leur procede de production |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE295852T1 true ATE295852T1 (de) | 2005-06-15 |
Family
ID=18608597
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01917554T ATE295852T1 (de) | 2000-03-30 | 2001-03-28 | Antibiotische tripropeptine und verfahren ihrer herstellung |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7271147B2 (de) |
| EP (1) | EP1285928B1 (de) |
| JP (1) | JP4054576B2 (de) |
| AT (1) | ATE295852T1 (de) |
| AU (1) | AU2001244594A1 (de) |
| DE (1) | DE60110908T2 (de) |
| ES (1) | ES2240434T3 (de) |
| WO (1) | WO2001074850A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5878303B2 (ja) * | 2010-05-25 | 2016-03-08 | 株式会社ゲノム創薬研究所 | 抗生物質含有画分、その抗生物質及びその抗生物質の製造方法 |
| JP5823733B2 (ja) * | 2010-05-25 | 2015-11-25 | 株式会社ゲノム創薬研究所 | 抗生物質産生微生物及びそれが産生した抗生物質 |
| ES2546515T3 (es) | 2010-05-25 | 2015-09-24 | Genome Pharmaceuticals Institute Co., Ltd. | Nuevo compuesto péptido cíclico, método para producirlo, agente anti-infeccioso, fracción que contiene antibiótico, antibiótico, método para producir antibiótico, microorganismo productor de antibiótico y antibiótico producido mediante el mismo |
| JP5878302B2 (ja) * | 2010-05-25 | 2016-03-08 | 株式会社ゲノム創薬研究所 | 新規環状ペプチド化合物とその製造方法及び感染症治療薬 |
| BRPI1005341B1 (pt) * | 2010-12-02 | 2016-12-20 | Bosch Do Brasil | galeria de combustível de material plástico com sistema de aquecimento |
| JPWO2012176909A1 (ja) * | 2011-06-24 | 2015-02-23 | 公益財団法人微生物化学研究会 | トリプロペプチン誘導体又はその薬理学上許容される塩、及び抗菌剤 |
| WO2013087764A1 (en) | 2011-12-14 | 2013-06-20 | Fraunhofer Gesellschaft zur Förderung der angewandten Forschung e.V. | Process for degrading a biofilm on surfaces of objects |
| US20150238543A1 (en) * | 2012-08-17 | 2015-08-27 | The Regents Of The University Of Michigan | Compositions and method for treating neutralizing microorganisms |
| US11744859B2 (en) | 2017-07-07 | 2023-09-05 | Epicentrx, Inc. | Compositions and methods for parenteral administration of therapeutic agents |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1266247A (en) * | 1985-03-25 | 1990-02-27 | Adrienne A. Tymiak | Antibiotic prepared from lysobacter sp. sc 14,067 |
-
2001
- 2001-03-28 DE DE60110908T patent/DE60110908T2/de not_active Expired - Lifetime
- 2001-03-28 AU AU2001244594A patent/AU2001244594A1/en not_active Abandoned
- 2001-03-28 JP JP2001572539A patent/JP4054576B2/ja not_active Expired - Fee Related
- 2001-03-28 WO PCT/JP2001/002578 patent/WO2001074850A1/ja active IP Right Grant
- 2001-03-28 EP EP01917554A patent/EP1285928B1/de not_active Expired - Lifetime
- 2001-03-28 US US10/239,324 patent/US7271147B2/en not_active Expired - Fee Related
- 2001-03-28 ES ES01917554T patent/ES2240434T3/es not_active Expired - Lifetime
- 2001-03-28 AT AT01917554T patent/ATE295852T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE60110908T2 (de) | 2006-01-19 |
| US7271147B2 (en) | 2007-09-18 |
| ES2240434T3 (es) | 2005-10-16 |
| EP1285928B1 (de) | 2005-05-18 |
| EP1285928A4 (de) | 2004-09-01 |
| WO2001074850A1 (fr) | 2001-10-11 |
| US20030162697A1 (en) | 2003-08-28 |
| DE60110908D1 (de) | 2005-06-23 |
| AU2001244594A1 (en) | 2001-10-15 |
| JP4054576B2 (ja) | 2008-02-27 |
| EP1285928A1 (de) | 2003-02-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |