ATE349464T1 - Derivate von glykopeptidantibiotika - Google Patents

Derivate von glykopeptidantibiotika

Info

Publication number
ATE349464T1
ATE349464T1 AT96909713T AT96909713T ATE349464T1 AT E349464 T1 ATE349464 T1 AT E349464T1 AT 96909713 T AT96909713 T AT 96909713T AT 96909713 T AT96909713 T AT 96909713T AT E349464 T1 ATE349464 T1 AT E349464T1
Authority
AT
Austria
Prior art keywords
derivatives
derivative compounds
glycopeptide antibiotics
activity against
glycopeptide antibiotic
Prior art date
Application number
AT96909713T
Other languages
English (en)
Inventor
Robin D G Cooper
Bret E Huff
Thalia I Nicas
John T Quatroche
Michael J Rodriguez
Nancy J Snyder
Michael A Staszak
Richard C Thompson
Stephen C Wilkie
Mark J Zweifel
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE349464T1 publication Critical patent/ATE349464T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compounds Of Unknown Constitution (AREA)
AT96909713T 1995-03-24 1996-03-14 Derivate von glykopeptidantibiotika ATE349464T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/410,155 US5840684A (en) 1994-01-28 1995-03-24 Glycopeptide antibiotic derivatives

Publications (1)

Publication Number Publication Date
ATE349464T1 true ATE349464T1 (de) 2007-01-15

Family

ID=23623466

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96909713T ATE349464T1 (de) 1995-03-24 1996-03-14 Derivate von glykopeptidantibiotika

Country Status (10)

Country Link
US (2) US5840684A (de)
EP (1) EP0817797B1 (de)
JP (1) JPH11502534A (de)
AT (1) ATE349464T1 (de)
AU (1) AU5312196A (de)
DE (1) DE69636791T2 (de)
DK (1) DK0817797T3 (de)
ES (1) ES2274525T3 (de)
PT (1) PT817797E (de)
WO (1) WO1996030401A1 (de)

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US6872804B2 (en) * 2000-06-22 2005-03-29 Theravance, Inc. Glycopeptide disulfide and thioester derivatives
US6828299B2 (en) 2000-06-22 2004-12-07 Theravance, Inc. Polyhydroxy glycopeptide derivatives
AU2001259303A1 (en) * 2000-06-22 2002-01-02 Advanced Medicine, Inc. Glycopeptide carboxy-saccharide derivatives
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US20070185015A1 (en) * 2005-02-28 2007-08-09 Chiron Corporation and North China Pharmaceutical Corporation Semi-synthetic desmethyl-vancomycin-based glycopeptides with antibiotic activity
US7632918B2 (en) * 2005-02-28 2009-12-15 Novartis Vaccines And Diagnostics, Inc. Semi-synthetic glycopeptides with antibiotic activity
AR053347A1 (es) * 2005-04-06 2007-05-02 Astrazeneca Ab Derivados de [1,3]tiazolo[4,5-d]pirimidin-2(3h)-ona 5,7-sustituidos
UA90707C2 (en) * 2005-04-06 2010-05-25 Астразенека Аб Novel 5-substituted 7-amino-[1,3]thiazolo[4,5-d]pyrimidine derivatives
US8652504B2 (en) 2005-09-22 2014-02-18 Medivas, Llc Solid polymer delivery compositions and methods for use thereof
EP1926780B1 (de) 2005-09-22 2013-08-14 Medivas, LLC Bis-( -amino)-diol-diester-haltige poly(esteramid) und poly(esterurethan)-zusammensetzungen und verwendungsverfahren
US20070173438A1 (en) * 2006-01-13 2007-07-26 The Scripps Research Institute [PSI[CH2NH]PG4] glycopeptide antibiotic analogs
TW200808818A (en) 2006-05-26 2008-02-16 Shionogi & Co Glycopeptide antibiotic derivatives
AU2007346657B2 (en) 2006-09-25 2013-07-11 Targanta Therapeutics Corp. Use of oritavancin for prevention and treatment of anthrax
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US8841440B2 (en) 2008-04-01 2014-09-23 Cornell University Organo-soluble chitosan salts and chitosan-derived biomaterials prepared thereof
ES2884673T3 (es) 2008-04-08 2021-12-10 Melinta Therapeutics Inc Oritavancina para inhibir y tratar biopelículas
CN102215858A (zh) 2008-08-30 2011-10-12 塔尔甘塔治疗公司 使用单剂量奥利万星的治疗方法
US9682061B2 (en) 2009-04-28 2017-06-20 The Medicines Company Methods of treating bacterial infections using oritavancin
ES2613806T3 (es) 2011-07-26 2017-05-26 The Medicines Company Ensayo de difusión con disco para oritavancina
CN104418941B (zh) * 2013-08-19 2017-11-07 爱斯医药科技(南京)有限公司 万古霉素衍生物、制备方法及其应用
US20160206688A1 (en) 2013-08-26 2016-07-21 The Medicines Company Methods for treating bacteremia and osteomyelitis using oritavancin
AU2014322817A1 (en) 2013-09-23 2016-04-21 Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR) Vancomycin-sugar conjugates and uses thereof
GB201402267D0 (en) 2014-02-10 2014-03-26 Cambridge Entpr Ltd Antibacterial agents
CA2954653C (en) * 2014-07-10 2023-01-24 The Scripps Research Institute N-(hydrophobe-substituted)vancosaminyl [.psi.[c(=nh)nh]tpg4]vancomycin and [.psi.[ch2nh]tpg4]vancomycin
CN107206050A (zh) * 2014-07-17 2017-09-26 医药公司 高纯度奥利万星及其生产方法
US20170342110A1 (en) * 2014-12-25 2017-11-30 Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR) Glycopeptides and uses thereof
WO2017123492A1 (en) * 2016-01-11 2017-07-20 Stc. Unm Inhibition and treatment of bacterial infections by sex-specific gper targeting
JP6671972B2 (ja) * 2016-01-15 2020-03-25 キヤノン株式会社 ファクシミリ装置、閾値設定方法、及びプログラム
MX2018009948A (es) 2016-02-18 2018-12-06 Melinta Therapeutics Inc Formulaciones de oritavancina.
US20200171124A1 (en) 2016-04-15 2020-06-04 Lupin Limited Topical compositions for ophthalmic and otic use
CN107619433B (zh) * 2016-07-15 2023-03-17 上海来益生物药物研究开发中心有限责任公司 糖肽类衍生物及其药学可接受的盐、制备方法和应用
CN108409837B (zh) * 2018-03-06 2021-09-24 上海来益生物药物研究开发中心有限责任公司 一组具有抗耐药性细菌活性的糖肽类化合物、其制备方法和应用

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Also Published As

Publication number Publication date
DE69636791T2 (de) 2007-10-11
EP0817797B1 (de) 2006-12-27
DE69636791D1 (de) 2007-02-08
JPH11502534A (ja) 1999-03-02
PT817797E (pt) 2007-02-28
AU5312196A (en) 1996-10-16
ES2274525T3 (es) 2007-05-16
US5977062A (en) 1999-11-02
US5840684A (en) 1998-11-24
WO1996030401A1 (en) 1996-10-03
EP0817797A4 (de) 2000-12-06
EP0817797A1 (de) 1998-01-14
DK0817797T3 (da) 2007-05-07

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