ATE247495T1 - Mineral-polymer hybrid-zusammensetzung - Google Patents
Mineral-polymer hybrid-zusammensetzungInfo
- Publication number
- ATE247495T1 ATE247495T1 AT00982802T AT00982802T ATE247495T1 AT E247495 T1 ATE247495 T1 AT E247495T1 AT 00982802 T AT00982802 T AT 00982802T AT 00982802 T AT00982802 T AT 00982802T AT E247495 T1 ATE247495 T1 AT E247495T1
- Authority
- AT
- Austria
- Prior art keywords
- calcium phosphate
- liquid
- phosphates
- thermo
- admixed
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/0047—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L24/0052—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with an inorganic matrix
- A61L24/0063—Phosphorus containing materials, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/0047—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L24/0073—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix
- A61L24/0084—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix containing fillers of phosphorus-containing inorganic compounds, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/08—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/20—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/24—Collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/30—Inorganic materials
- A61L27/32—Phosphorus-containing materials, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L27/42—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix
- A61L27/425—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix of phosphorus containing material, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/52—Hydrogels or hydrocolloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
- C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/06—Flowable or injectable implant compositions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Materials Engineering (AREA)
- Composite Materials (AREA)
- Surgery (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Polymers & Plastics (AREA)
- Dispersion Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Materials For Medical Uses (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16995499P | 1999-12-09 | 1999-12-09 | |
PCT/CA2000/001492 WO2001041822A1 (en) | 1999-12-09 | 2000-12-08 | Mineral-polymer hybrid composition |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE247495T1 true ATE247495T1 (de) | 2003-09-15 |
Family
ID=22617898
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00981124T ATE243049T1 (de) | 1999-12-09 | 2000-12-08 | Mineral-polymer hybrid-zusammensetzung |
AT00982802T ATE247495T1 (de) | 1999-12-09 | 2000-12-08 | Mineral-polymer hybrid-zusammensetzung |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00981124T ATE243049T1 (de) | 1999-12-09 | 2000-12-08 | Mineral-polymer hybrid-zusammensetzung |
Country Status (6)
Country | Link |
---|---|
US (2) | US20030199615A1 (de) |
EP (2) | EP1237585B1 (de) |
AT (2) | ATE243049T1 (de) |
AU (2) | AU1979201A (de) |
DE (2) | DE60003459T2 (de) |
WO (2) | WO2001041821A1 (de) |
Families Citing this family (129)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2427938C (en) | 1999-11-15 | 2010-02-16 | Bio Syntech Canada Inc. | Novel temperature-controlled and ph-dependant self-gelling biopolymeric aqueous solution, composition and preparation thereof |
US20030158302A1 (en) * | 1999-12-09 | 2003-08-21 | Cyric Chaput | Mineral-polymer hybrid composition |
AU1979201A (en) * | 1999-12-09 | 2001-06-18 | Bio Syntech Canada Inc | Mineral-polymer hybrid composition |
US7820191B2 (en) | 2000-04-28 | 2010-10-26 | Skeletal Kinetics, Llc | Calcium phosphate cements prepared from silicate solutions |
CN1471412B8 (zh) | 2000-06-29 | 2016-06-15 | 生物合成技术加拿大公司 | 用于修复和再生软骨和其它组织的组合物以及该组合物的用途 |
WO2002040070A2 (en) * | 2000-11-15 | 2002-05-23 | Bio Syntech Canada Inc. | Method for restoring a damaged or degenerated intervertebral disc |
CA2429165A1 (en) * | 2000-11-15 | 2002-05-23 | Bio Syntech Canada Inc. | Filler composition for soft tissue augmentation and reconstructive surgery |
US20020114795A1 (en) | 2000-12-22 | 2002-08-22 | Thorne Kevin J. | Composition and process for bone growth and repair |
US20030134811A1 (en) * | 2001-10-09 | 2003-07-17 | John Jackson | Methods and compositions comprising hydroxyapatite useful for the administration of therapeutic agents |
JP2003128704A (ja) | 2001-10-24 | 2003-05-08 | Matsumoto Shika Univ | キチン・キトサンの低分子化方法及び骨伝導物の製造方法 |
US20030204180A1 (en) * | 2002-04-30 | 2003-10-30 | Kimberly-Clark Worldwide, Inc. | Temperature responsive delivery systems |
US7273523B2 (en) | 2002-06-07 | 2007-09-25 | Kyphon Inc. | Strontium-apatite-cement-preparations, cements formed therefrom, and uses thereof |
US7244445B2 (en) * | 2002-07-29 | 2007-07-17 | Poly Med, Inc | Conformable, absorbable, solid composite preforms and their use for bone tissue engineering |
AU2002337479A1 (en) * | 2002-09-04 | 2004-03-29 | Hadasit Medical Research Services & Development Ltd. | Compositions comprising bone marrow cells, demineralized bone matrix and rtg polymers for use in the induction of bone and cartilage formation |
AU2003287812A1 (en) * | 2002-12-03 | 2004-06-23 | Bio Syntech Canada Inc. | Method for treating a tumor using a thermo-gelling chitosan composition |
US7371256B2 (en) | 2002-12-16 | 2008-05-13 | Poly-Med, Inc | Composite vascular constructs with selectively controlled properties |
FR2850282B1 (fr) | 2003-01-27 | 2007-04-06 | Jerome Asius | Implant injectable a base de ceramique pour le comblement de rides, depressions cutanees et cicatrices, et sa preparation |
JP4634027B2 (ja) * | 2003-05-16 | 2011-02-16 | 花王株式会社 | ビタミンd様活性代替用剤 |
US7306786B2 (en) * | 2003-07-28 | 2007-12-11 | Skeletal Kinetics, Llc | Calcium phosphate cements comprising a water-soluble contrast agent |
US7261718B2 (en) * | 2003-09-11 | 2007-08-28 | Skeletal Kinetics Llc | Use of vibration with polymeric bone cements |
US7261717B2 (en) * | 2003-09-11 | 2007-08-28 | Skeletal Kinetics Llc | Methods and devices for delivering orthopedic cements to a target bone site |
DE60331654D1 (de) * | 2003-10-17 | 2010-04-22 | Neurofood Ab Oy | Nicht-radioaktives Strontiummittel zur Behandlung von Krebs |
US7252833B2 (en) * | 2003-11-18 | 2007-08-07 | Skeletal Kinetics, Llc | Calcium phosphate cements comprising an osteoclastogenic agent |
EP1740233A1 (de) * | 2004-03-08 | 2007-01-10 | Dr.h.c. Robert Mathys Stiftung | Hydraulischer zement auf basis von calciumphosphat für chirurgische anwendungen |
US9707024B2 (en) | 2004-03-09 | 2017-07-18 | Skeletal Kinetics, Llc | Use of vibration in composite fixation |
US8118812B2 (en) | 2004-03-09 | 2012-02-21 | Skeletal Kinetics, Llc | Use of vibration in composite fixation |
US8168692B2 (en) | 2004-04-27 | 2012-05-01 | Kyphon Sarl | Bone substitute compositions and method of use |
FR2869544B1 (fr) * | 2004-05-03 | 2006-07-21 | Centre Nat Rech Scient Cnrse | Composition pour ciment injectable, utile comme substitut osseux |
US7252841B2 (en) * | 2004-05-20 | 2007-08-07 | Skeletal Kinetics, Llc | Rapid setting calcium phosphate cements |
US20050257714A1 (en) * | 2004-05-20 | 2005-11-24 | Constantz Brent R | Orthopedic cements comprising a barium apatite contrast agent |
US8119153B2 (en) | 2004-08-26 | 2012-02-21 | Boston Scientific Scimed, Inc. | Stents with drug eluting coatings |
WO2006034420A2 (en) * | 2004-09-21 | 2006-03-30 | Thomas Joseph Lally | Multi-purpose bio-material composition |
WO2006076426A2 (en) * | 2005-01-12 | 2006-07-20 | Lally Thomas J | Multi-purpose bio-material composition |
US9078884B2 (en) | 2004-09-21 | 2015-07-14 | Thomas Joseph Lally | Bio-material composition and method for spinal fusion |
US20060074422A1 (en) * | 2004-09-27 | 2006-04-06 | Story Brooks J | Suture anchor and void filler combination |
US20060067971A1 (en) * | 2004-09-27 | 2006-03-30 | Story Brooks J | Bone void filler |
US20060083769A1 (en) * | 2004-10-14 | 2006-04-20 | Mukesh Kumar | Method and apparatus for preparing bone |
US7473678B2 (en) | 2004-10-14 | 2009-01-06 | Biomimetic Therapeutics, Inc. | Platelet-derived growth factor compositions and methods of use thereof |
KR101366911B1 (ko) | 2004-11-16 | 2014-02-24 | 쓰리엠 이노베이티브 프로퍼티즈 컴파니 | 인-함유 표면 처리제를 포함하는 치과용 충전제, 및 그의조성물 및 방법 |
KR20070086324A (ko) | 2004-11-16 | 2007-08-27 | 쓰리엠 이노베이티브 프로퍼티즈 컴파니 | 칼슘과 인을 방출하는 유리를 함유한 치과용 조성물 |
WO2006055327A1 (en) | 2004-11-16 | 2006-05-26 | 3M Innovative Properties Company | Dental fillers and compositions including phosphate salts |
US8278368B2 (en) | 2004-11-16 | 2012-10-02 | 3M Innnovatve Properties Company | Dental fillers, methods, compositions including a caseinate |
DE102005034420A1 (de) * | 2004-12-23 | 2006-07-06 | Ossacur Ag | Gelartiges Material zur Füllung von Knochen- und/oder Knorpeldefekten |
JP2008527033A (ja) * | 2005-01-19 | 2008-07-24 | ボンオス・メディカル・アー・ベー | 増殖因子組成物 |
US7459018B2 (en) | 2005-04-08 | 2008-12-02 | Howmedica Leibinger Inc. | Injectable calcium phosphate cement |
US7416602B2 (en) | 2005-04-08 | 2008-08-26 | Howmedica Leibinger, Inc. | Calcium phosphate cement |
US20090148486A1 (en) * | 2005-04-28 | 2009-06-11 | Helen Lu | Compositions and methods for treating pulp inflammations caused by infection or trauma |
US7651701B2 (en) | 2005-08-29 | 2010-01-26 | Sanatis Gmbh | Bone cement composition and method of making the same |
US9101436B2 (en) * | 2005-10-21 | 2015-08-11 | Ada Foundation | Dental and endodontic filling materials and methods |
US20090075383A1 (en) * | 2005-11-04 | 2009-03-19 | Bio Syntech Canada Inc. | Composition and method for efficient delivery of nucleic acids to cells using chitosan |
JP5368102B2 (ja) | 2005-11-17 | 2013-12-18 | バイオミメティック セラピューティクス, インコーポレイテッド | rhPDGF−BB及び生体適合性マトリックスを用いた顎顔面骨強化 |
WO2007064304A1 (en) * | 2005-12-01 | 2007-06-07 | National University Of Singapore | Biocompatible composition and uses thereof |
US7674864B2 (en) * | 2005-12-23 | 2010-03-09 | Boston Scientific Scimed, Inc. | Polymeric hybrid precursors, polymeric hybrid precursor composite matrices, medical devices, and methods |
US8455088B2 (en) | 2005-12-23 | 2013-06-04 | Boston Scientific Scimed, Inc. | Spun nanofiber, medical devices, and methods |
US10130561B2 (en) * | 2006-01-31 | 2018-11-20 | Robert L. Karlinsey | Functionalized calcium phosphate hybrid systems for confectionery and foodstuff applications |
ES2443581T3 (es) * | 2006-02-09 | 2014-02-19 | Biomimetic Therapeutics, Llc | Composiciones y métodos para el tratamiento de hueso |
US20070258916A1 (en) * | 2006-04-14 | 2007-11-08 | Oregon Health & Science University | Oral compositions for treating tooth hypersensitivity |
US7507286B2 (en) * | 2006-06-08 | 2009-03-24 | Sanatis Gmbh | Self-foaming cement for void filling and/or delivery systems |
US9161967B2 (en) | 2006-06-30 | 2015-10-20 | Biomimetic Therapeutics, Llc | Compositions and methods for treating the vertebral column |
EP2049145B1 (de) | 2006-06-30 | 2018-03-14 | BioMimetic Therapeutics, LLC | Pdgf-biomatrix-zusammensetzungen und methode für die behandlung von rotationsmanschettenverletzungen |
DE102006042142A1 (de) | 2006-09-06 | 2008-03-27 | Curasan Ag | Phasen- und sedimentationsstabile, plastisch verformbare Zubereitung mit intrinsischer Porenbildung, bspw. zum Auffüllen von Knochendefekten bzw. zur Verwendung als Knochenersatzmaterial, und Verfahren zu deren Herstellung |
KR100784134B1 (ko) * | 2006-10-09 | 2007-12-12 | 주식회사 대웅 | 상피세포성장인자를 함유하는 안정한 구내염 치료용 액상조성물 |
EP2086598B1 (de) | 2006-11-03 | 2015-05-27 | BioMimetic Therapeutics, LLC | Zusammensetzungen und verfahren für behandlungen von arthrodese |
NL1032851C2 (nl) * | 2006-11-10 | 2008-05-14 | Fondel Finance B V | Kit en werkwijze voor het fixeren van een prothese of deel daarvan en/of het vullen van benige defecten. |
AU2006352228A1 (en) * | 2006-12-22 | 2008-07-03 | Mathys Ag Bettlach | Precursor for the preparation of a pasty bone replacement material by admixture of a liquid |
US9023373B2 (en) * | 2007-01-31 | 2015-05-05 | Indiana Nanotech | Functionalized calcium phosphate hybrid systems for the remineralization of teeth and a method for producing the same |
US9205036B2 (en) | 2007-01-31 | 2015-12-08 | Robert Karlinsey | Dental composition |
US20100203144A1 (en) * | 2007-08-23 | 2010-08-12 | University Of Virginia Patent Foundation | Immobilized Metallic Nanoparticles as Unique Materials for Therapeutic and Biosensor Applications |
US20110136935A1 (en) * | 2007-08-30 | 2011-06-09 | National University Of Singapore | Bone and/or dental cement composition and uses thereof |
EP2211752A4 (de) * | 2007-10-25 | 2013-10-02 | Univ Columbia | Biopulpa |
WO2009076369A1 (en) * | 2007-12-10 | 2009-06-18 | The Trustees Of The University Of Pennsylvania | Chitosan-based matrices and uses thereof |
JP5436229B2 (ja) * | 2008-02-07 | 2014-03-05 | クラレノリタケデンタル株式会社 | リン酸カルシウム組成物粉体の製造方法 |
AU2009212151C1 (en) | 2008-02-07 | 2015-09-17 | Biomimetic Therapeutics, Llc | Compositions and methods for distraction osteogenesis |
US8846003B2 (en) | 2008-03-27 | 2014-09-30 | Symic Biomedical, Inc. | Collagen-binding synthetic peptidoglycans, preparation, and methods of use |
US7968616B2 (en) | 2008-04-22 | 2011-06-28 | Kyphon Sarl | Bone cement composition and method |
CA2735885C (en) | 2008-09-09 | 2018-08-28 | Biomimetic Therapeutics, Inc. | Platelet-derived growth factor compositions and methods for the treatment of tendon and ligament injuries |
US8709149B2 (en) | 2008-11-12 | 2014-04-29 | Ossdsign Ab | Hydraulic cements, methods and products |
US10105197B1 (en) * | 2009-03-26 | 2018-10-23 | Fernando Colon | Method of treatment for periodontal pockets |
EP2515959A1 (de) * | 2009-12-21 | 2012-10-31 | Coloplast A/S | Benetzungsmittel mit niedermolekularem polyol und puffer |
US8883739B2 (en) | 2010-01-19 | 2014-11-11 | The Trustees Of Columbia University In The City Of New York | Osteocalcin as a treatment for male reproductive disorders |
NZ601559A (en) | 2010-02-22 | 2014-10-31 | Biomimetic Therapeutics Llc | Platelet-derived growth factor compositions and methods for the treatment of tendinopathies |
EP2544627B1 (de) | 2010-03-10 | 2018-05-02 | OssDsign AB | Implantate zur korrektur von gewebedefekten |
US8614190B2 (en) * | 2010-06-30 | 2013-12-24 | Industrial Technology Research Institute | Thermal responsive composition for treating bone diseases |
ES2714701T3 (es) | 2010-11-10 | 2019-05-29 | Stryker European Holdings I Llc | Proceso para la preparación de una espuma ósea polimérica |
DE102010055561B4 (de) * | 2010-12-23 | 2015-12-31 | Heraeus Medical Gmbh | Beschichtungsverfahren und Beschichtungsvorrichtung |
US11730760B2 (en) | 2011-04-01 | 2023-08-22 | The Bioregentech Institute, Inc. | Laser assisted wound healing protocol and system |
US11389663B2 (en) | 2011-04-01 | 2022-07-19 | Bioregentech, Inc. | Laser assisted wound healing protocol and system |
EP2714718B1 (de) | 2011-05-24 | 2017-01-11 | Symic IP, LLC | Hyaluronsäurebindende synthetische peptidoglycane, ihre herstellung und verfahren zu ihrer verwendung |
TWI423828B (zh) * | 2011-08-17 | 2014-01-21 | Univ Nat Cheng Kung | 供低骨質密度患者使用之骨植入物 |
US9463046B2 (en) | 2011-08-22 | 2016-10-11 | Ossdsign Ab | Implants and methods for using such implants to fill holes in bone tissue |
US8591645B2 (en) | 2011-09-09 | 2013-11-26 | Ossdsign Ab | Hydraulic cements with optimized grain size distribution, methods, articles and kits |
US20130066327A1 (en) | 2011-09-09 | 2013-03-14 | Håkan Engqvist | Hydraulic cement compositions with low ph methods, articles and kits |
CN103014801A (zh) * | 2011-09-20 | 2013-04-03 | 天津市玄真生物医药科技发展有限公司 | 一种钛基羟基磷灰石生物医用复合材料的电沉积制备方法 |
CN102492974A (zh) * | 2011-12-30 | 2012-06-13 | 浙江大学 | 钛种植体表面制备可降解镁掺杂非晶态磷酸钙涂层的方法 |
JP6232048B2 (ja) | 2012-04-23 | 2017-11-15 | ジェニス エイチエフ. | 骨移植片代用材としての部分的に脱アセチル化されたキチンを含む自硬性の生体活性セメント組成物 |
CN102899698A (zh) * | 2012-09-29 | 2013-01-30 | 浙江大学 | 金属钛表面制备羟基磷灰石树枝状微纳复合涂层电化学法 |
US9272072B1 (en) | 2012-10-19 | 2016-03-01 | Nuvasive, Inc. | Osteoinductive bone graft substitute |
JP6270870B2 (ja) * | 2012-12-14 | 2018-01-31 | オスディーサイン アーベー | セメント形成組成物、モネタイトセメント、移植片及び骨欠損を修復する方法 |
CN105120802B (zh) | 2013-02-12 | 2018-01-12 | 奥斯设计公司 | 镶嵌型植入物、试剂盒和用于矫正骨缺损的方法 |
WO2014159623A2 (en) * | 2013-03-14 | 2014-10-02 | Nevins Alan | Root canal for tissue in-growth |
WO2014152497A2 (en) | 2013-03-15 | 2014-09-25 | The Trustees Of Columbia University In The City Of New York | Osteocalcin as a treatment for cognitive disorders |
AU2014233537A1 (en) | 2013-03-15 | 2015-09-10 | Symic Ip, Llc | Extracellular matrix-binding synthetic peptidoglycans |
US20160296664A1 (en) | 2013-04-12 | 2016-10-13 | The Trustees Of Columbia University In The City Of New York | Methods for host cell homing and dental pulp regeneration |
CA2909645A1 (en) * | 2013-04-16 | 2014-10-23 | Molecular Systems, Ltd. | Laser assisted periodontium and osseus regeneration protocol |
GB201313898D0 (en) * | 2013-08-02 | 2013-09-18 | Bradford | Formulations and materials with cationic polymers |
US9192692B2 (en) | 2013-10-24 | 2015-11-24 | Medtronic Xomed, Inc. | Chitosan stenting paste |
US9192574B2 (en) | 2013-10-24 | 2015-11-24 | Medtronic Xomed, Inc. | Chitosan paste wound dressing |
CN103816572A (zh) * | 2014-03-03 | 2014-05-28 | 张宪 | 一种可注射多孔磷酸钙骨修复材料的制备方法 |
WO2015164822A1 (en) | 2014-04-25 | 2015-10-29 | Purdue Research Foundation | Collagen binding synthetic peptidoglycans for treatment of endothelial dysfunction |
ES2555235B1 (es) * | 2014-06-25 | 2016-10-05 | Universitat Politècnica De Catalunya | Nuevo proceso de fabricación en un solo paso de biomateriales espumados |
US10881519B2 (en) | 2014-08-14 | 2021-01-05 | Ossdsign Ab | Bone implants for correcting bone defects |
WO2016081728A1 (en) | 2014-11-19 | 2016-05-26 | The Trustees Of Columbia University In The City Of New York | Osteocalcin as a treatment for frailty associated with aging |
MX2018005547A (es) | 2015-11-03 | 2018-11-09 | Zoetis Services Llc | Compuestos polimericos sol-gel y sus usos. |
EP3228334A1 (de) * | 2016-04-06 | 2017-10-11 | Graftys | Blut-enthaltende phosphorcalciumhaltige zementzusammensetzung |
RU2617050C1 (ru) * | 2016-04-11 | 2017-04-19 | Виталий Васильевич Гузеев | Биоактивный композиционный материал для замещения костных дефектов и способ его получения |
SG11201809197XA (en) | 2016-04-27 | 2018-11-29 | Anika Therapeutics Inc | Compositions for use in treating tendon degeneration |
EP3448447B1 (de) * | 2016-04-27 | 2023-05-03 | Anika Therapeutics, Inc. | Verfahren und zusammensetzungen zur behandlung von degenerierten knochen |
US10709733B2 (en) | 2016-08-11 | 2020-07-14 | Regents Of The University Of Minnesota | Nonsurgical techniques for restoring tooth enamel |
EP3538001A4 (de) * | 2016-11-10 | 2020-11-25 | Bioregentech | Lasergestütztes wundheilungsprotokoll und system |
US11654293B2 (en) | 2016-11-10 | 2023-05-23 | The Bioregentech Institute, Inc. | Laser assisted wound healing protocol and system |
WO2018089954A1 (en) | 2016-11-10 | 2018-05-17 | BioRegentech | Laser assisted wound healing protocol and system |
CN110573066A (zh) * | 2017-03-02 | 2019-12-13 | 光谱Md公司 | 用于多光谱截肢部位分析的机器学习系统和技术 |
US20180326124A1 (en) * | 2017-05-12 | 2018-11-15 | Bone Solutions, Inc. | Bio-Material Composition and Methods of Use |
CN110809478A (zh) | 2017-07-07 | 2020-02-18 | 斯米克Ip有限公司 | 合成的生物缀合物 |
EP3651743B1 (de) | 2017-07-14 | 2023-10-04 | The University of Chicago | Gefriergetrocknete formulierungen mit nanopartikeln und verfahren zur gefriertrocknung |
CN108853599B (zh) * | 2018-07-27 | 2021-03-05 | 王宇清 | 一种富氧温敏型水凝胶及其制备方法 |
CN111214699A (zh) * | 2020-01-08 | 2020-06-02 | 广州贝奥吉因生物科技股份有限公司 | 一种用于周围神经损伤修复的水凝胶及其制备方法 |
CN113769160A (zh) * | 2021-08-23 | 2021-12-10 | 广州润虹医药科技股份有限公司 | 一种温敏性微球及其即用型温敏性磷酸钙骨水泥 |
CN115778845B (zh) * | 2023-02-07 | 2023-04-25 | 荷本世新(北京)生物科技有限公司 | 蛋白组合物及其制备方法和用途 |
Family Cites Families (101)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS51136033A (en) * | 1975-05-19 | 1976-11-25 | Nissan Motor Co Ltd | Exhaust reflux device of engine |
US4185618A (en) * | 1976-01-05 | 1980-01-29 | Population Research, Inc. | Promotion of fibrous tissue growth in fallopian tubes for female sterilization |
US4391909A (en) * | 1979-03-28 | 1983-07-05 | Damon Corporation | Microcapsules containing viable tissue cells |
US4394373A (en) * | 1981-04-06 | 1983-07-19 | Malette William Graham | Method of achieving hemostasis |
US4424346A (en) * | 1981-06-04 | 1984-01-03 | Canadian Patents And Development Ltd. | Derivatives of chitins, chitosans and other polysaccharides |
SE441009B (sv) * | 1982-03-08 | 1985-09-02 | Kjell Nilsson | Sett att immobilisera levande biomaterial i perlformiga polymerer |
US4474769A (en) * | 1983-05-13 | 1984-10-02 | Pfanstiehl Laboratories, Inc. | Chitosan as a contraceptive |
US4659700A (en) * | 1984-03-02 | 1987-04-21 | Johnson & Johnson Products, Inc. | Chitosan-glycerol-water gel |
US4722948A (en) * | 1984-03-16 | 1988-02-02 | Dynatech Corporation | Bone replacement and repair putty material from unsaturated polyester resin and vinyl pyrrolidone |
US4731081A (en) * | 1984-09-11 | 1988-03-15 | Mentor Corporation | Rupture-resistant prosthesis with creasable shell and method of forming same |
US4895724A (en) | 1985-06-07 | 1990-01-23 | Pfizer Inc. | Chitosan compositions for controlled and prolonged release of macromolecules |
JPS624702A (ja) * | 1985-06-28 | 1987-01-10 | Lion Corp | 水溶性アシル化キトサンの製造方法 |
US6005161A (en) * | 1986-01-28 | 1999-12-21 | Thm Biomedical, Inc. | Method and device for reconstruction of articular cartilage |
US5902741A (en) * | 1986-04-18 | 1999-05-11 | Advanced Tissue Sciences, Inc. | Three-dimensional cartilage cultures |
US4803075A (en) * | 1986-06-25 | 1989-02-07 | Collagen Corporation | Injectable implant composition having improved intrudability |
CA1340581C (en) * | 1986-11-20 | 1999-06-08 | Joseph P. Vacanti | Chimeric neomorphogenesis of organs by controlled cellular implantation using artificial matrices |
US5736372A (en) * | 1986-11-20 | 1998-04-07 | Massachusetts Institute Of Technology | Biodegradable synthetic polymeric fibrous matrix containing chondrocyte for in vivo production of a cartilaginous structure |
EP0298501B1 (de) * | 1987-07-10 | 1992-04-08 | Asahi Kogaku Kogyo Kabushiki Kaisha | Zusammensetzung zur Herstellung eines härtbaren kalziumphosphatartigen Materials und Verfahren zur Produktion eines derartigen Materials |
US6610669B1 (en) | 1987-09-18 | 2003-08-26 | Genzyme Corporation | Water insoluble derivatives of polyanionic polysaccharides |
GB8803697D0 (en) * | 1988-02-17 | 1988-03-16 | Deltanine Research Ltd | Clinical developments using amniotic membrane cells |
US4956350A (en) * | 1988-08-18 | 1990-09-11 | Minnesota Mining And Manufacturing Company | Wound filling compositions |
US4938763B1 (en) | 1988-10-03 | 1995-07-04 | Atrix Lab Inc | Biodegradable in-situ forming implants and method of producing the same |
US5126141A (en) * | 1988-11-16 | 1992-06-30 | Mediventures Incorporated | Composition and method for post-surgical adhesion reduction with thermo-irreversible gels of polyoxyalkylene polymers and ionic polysaccharides |
US5073202A (en) | 1989-03-09 | 1991-12-17 | Micro Vesicular Systems, Inc. | Method of using a biodegradable superabsorbing sponge |
US5324519A (en) | 1989-07-24 | 1994-06-28 | Atrix Laboratories, Inc. | Biodegradable polymer composition |
US5811094A (en) * | 1990-11-16 | 1998-09-22 | Osiris Therapeutics, Inc. | Connective tissue regeneration using human mesenchymal stem cell preparations |
US5318780A (en) | 1991-10-30 | 1994-06-07 | Mediventures Inc. | Medical uses of in situ formed gels |
GB2261672A (en) * | 1991-11-18 | 1993-05-26 | Michael Braden | The use of biomaterials for tissue repair |
IL100096A (en) * | 1991-11-20 | 1996-03-31 | Univ Ramot | Method for entrapment of active materials in chitosan |
US5658593A (en) * | 1992-01-16 | 1997-08-19 | Coletica | Injectable compositions containing collagen microcapsules |
US5708152A (en) | 1992-03-27 | 1998-01-13 | Ciba Specialty Chemicals Corporation | N-substituted chitosan derivatives in a process for their preparation |
US5266326A (en) * | 1992-06-30 | 1993-11-30 | Pfizer Hospital Products Group, Inc. | In situ modification of alginate |
US5871985A (en) * | 1992-09-28 | 1999-02-16 | Brown University Research Foundation | Particulate non cross-linked chitosan core matrices for encapsulated cells |
US5709854A (en) * | 1993-04-30 | 1998-01-20 | Massachusetts Institute Of Technology | Tissue formation by injecting a cell-polymeric solution that gels in vivo |
US5368051A (en) * | 1993-06-30 | 1994-11-29 | Dunn; Allan R. | Method of regenerating articular cartilage |
CA2130295A1 (en) | 1993-08-26 | 1995-02-27 | Richard A. Berg | Ionically crosslinked glycosaminoglycan gels for soft tissue augmentation and drug delivery |
US5531716A (en) | 1993-09-29 | 1996-07-02 | Hercules Incorporated | Medical devices subject to triggered disintegration |
US6743783B1 (en) | 1993-12-01 | 2004-06-01 | Marine Polymer Technologies, Inc. | Pharmaceutical compositions comprising poly-β-1→4-N-acetylglucosamine |
US5422116A (en) * | 1994-02-18 | 1995-06-06 | Ciba-Geigy Corporation | Liquid ophthalmic sustained release delivery system |
US6251137B1 (en) | 1994-03-23 | 2001-06-26 | Mcghan Medical Corporation | Synthetic triglyceride filler material for surgically implanted prostheses |
US5626861A (en) * | 1994-04-01 | 1997-05-06 | Massachusetts Institute Of Technology | Polymeric-hydroxyapatite bone composite |
US5723331A (en) * | 1994-05-05 | 1998-03-03 | Genzyme Corporation | Methods and compositions for the repair of articular cartilage defects in mammals |
WO1995033421A1 (en) * | 1994-06-06 | 1995-12-14 | Case Western Reserve University | Biomatrix for tissue regeneration |
AU2731295A (en) * | 1994-07-08 | 1996-02-09 | Sulzer Medizinaltechnik Ag | Method of manufacturing implant materials |
SE9402528D0 (sv) * | 1994-07-19 | 1994-07-19 | Astra Ab | Hårdvävnadsstimulerande med el |
SE9402531L (sv) * | 1994-07-19 | 1996-01-20 | Medicarb Ab | Sårläkningsmedel |
US5510102A (en) * | 1995-01-23 | 1996-04-23 | The Regents Of The University Of California | Plasma and polymer containing surgical hemostatic adhesives |
US5749874A (en) * | 1995-02-07 | 1998-05-12 | Matrix Biotechnologies, Inc. | Cartilage repair unit and method of assembling same |
US6080194A (en) * | 1995-02-10 | 2000-06-27 | The Hospital For Joint Disease Orthopaedic Institute | Multi-stage collagen-based template or implant for use in the repair of cartilage lesions |
US5906934A (en) * | 1995-03-14 | 1999-05-25 | Morphogen Pharmaceuticals, Inc. | Mesenchymal stem cells for cartilage repair |
NL9500580A (nl) * | 1995-03-27 | 1996-11-01 | Hollandse Signaalapparaten Bv | Phased array antenne voorzien van een calibratienetwerk. |
US5620706A (en) | 1995-04-10 | 1997-04-15 | Universite De Sherbrooke | Polyionic insoluble hydrogels comprising xanthan and chitosan |
EP0830149A1 (de) * | 1995-06-06 | 1998-03-25 | Osteogenics Inc. | Bioverträgliche hydroxyapatitformulierungen und ihre verwendung |
US5655546A (en) * | 1995-06-07 | 1997-08-12 | Halpern; Alan A. | Method for cartilage repair |
EP0830381A4 (de) * | 1995-06-09 | 2000-11-22 | William N Drohan | Chitinhydrogele, herstellungsverfahren und anwendung |
JP3881707B2 (ja) * | 1995-07-20 | 2007-02-14 | 学校法人松本歯科大学 | 骨形成促進剤の製造方法及び骨形成促進剤を用いた骨形成組成物の製造方法 |
TW389694B (en) * | 1995-08-17 | 2000-05-11 | Novartis Ag | Compositions including o-carboxyalkyl chitosan and methods of use in ophthalmics |
AU1051597A (en) * | 1995-11-09 | 1997-05-29 | University Of Massachusetts | Tissue re-surfacing with hydrogel-cell compositions |
DE69634303T2 (de) * | 1995-11-16 | 2006-01-05 | Case Western Reserve University, Cleveland | Chondrogene in vitro induktion von menschlichen mensenchymalen stammzellen |
US6200606B1 (en) * | 1996-01-16 | 2001-03-13 | Depuy Orthopaedics, Inc. | Isolation of precursor cells from hematopoietic and nonhematopoietic tissues and their use in vivo bone and cartilage regeneration |
US5842477A (en) * | 1996-02-21 | 1998-12-01 | Advanced Tissue Sciences, Inc. | Method for repairing cartilage |
US6060534A (en) | 1996-07-11 | 2000-05-09 | Scimed Life Systems, Inc. | Medical devices comprising ionically and non-ionically crosslinked polymer hydrogels having improved mechanical properties |
US6649192B2 (en) | 1996-07-29 | 2003-11-18 | Universidade De Santiago De Compostela | Application of nanoparticles based on hydrophilic polymers as pharmaceutical forms |
US6706690B2 (en) | 1999-06-10 | 2004-03-16 | Baxter Healthcare Corporation | Hemoactive compositions and methods for their manufacture and use |
US7320962B2 (en) | 1996-08-27 | 2008-01-22 | Baxter International Inc. | Hemoactive compositions and methods for their manufacture and use |
US5866415A (en) * | 1997-03-25 | 1999-02-02 | Villeneuve; Peter E. | Materials for healing cartilage and bone defects |
CA2212300A1 (en) * | 1997-08-04 | 1999-02-04 | Abdellatif Chenite | In vitro or in vivo gelfying chitosan and therapeutic uses thereof |
US6110209A (en) * | 1997-08-07 | 2000-08-29 | Stone; Kevin R. | Method and paste for articular cartilage transplantation |
US6417247B1 (en) * | 1997-10-14 | 2002-07-09 | Beth L. Armstrong | Polymer/ceramic composites |
US7019192B2 (en) | 1998-02-27 | 2006-03-28 | Musculoskeletal Transplant Foundation | Composition for filling bone defects |
US7045141B2 (en) | 1998-02-27 | 2006-05-16 | Musculoskeletal Transplant Foundation | Allograft bone composition having a gelatin binder |
US6911212B2 (en) | 1998-02-27 | 2005-06-28 | Musculoskeletal Transplant Foundation | Malleable putty and flowable paste with allograft bone having residual calcium for filling bone defects |
US6179872B1 (en) * | 1998-03-17 | 2001-01-30 | Tissue Engineering | Biopolymer matt for use in tissue repair and reconstruction |
US20030147860A1 (en) | 2002-02-07 | 2003-08-07 | Marchosky J. Alexander | Compositions and methods for forming and strengthening bone |
US6372257B1 (en) * | 1999-06-29 | 2002-04-16 | J. Alexander Marchosky | Compositions and methods for forming and strengthening bone |
US6429013B1 (en) | 1999-08-19 | 2002-08-06 | Artecel Science, Inc. | Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair |
CA2427938C (en) | 1999-11-15 | 2010-02-16 | Bio Syntech Canada Inc. | Novel temperature-controlled and ph-dependant self-gelling biopolymeric aqueous solution, composition and preparation thereof |
US20030158302A1 (en) | 1999-12-09 | 2003-08-21 | Cyric Chaput | Mineral-polymer hybrid composition |
AU1979201A (en) | 1999-12-09 | 2001-06-18 | Bio Syntech Canada Inc | Mineral-polymer hybrid composition |
CN1471412B8 (zh) | 2000-06-29 | 2016-06-15 | 生物合成技术加拿大公司 | 用于修复和再生软骨和其它组织的组合物以及该组合物的用途 |
US20040047892A1 (en) | 2000-11-15 | 2004-03-11 | Desrosiers Eric Andre | Filler composition for soft tissue augmentation and reconstructive surgery |
WO2002040070A2 (en) | 2000-11-15 | 2002-05-23 | Bio Syntech Canada Inc. | Method for restoring a damaged or degenerated intervertebral disc |
US6756363B1 (en) | 2000-11-17 | 2004-06-29 | Wound Healing Of Oklahoma, Inc. | Solutions and films of glycated chitosan |
JP4959916B2 (ja) | 2001-08-14 | 2012-06-27 | メディポスト・カンパニー・リミテッド | 関節軟骨損傷治療用組成物 |
US8740973B2 (en) | 2001-10-26 | 2014-06-03 | Icon Medical Corp. | Polymer biodegradable medical device |
US20050004057A1 (en) | 2001-12-14 | 2005-01-06 | Isabelle Boucher | Chitosan oligosaccharides and uses thereof |
US7514249B2 (en) | 2002-04-18 | 2009-04-07 | The University Of Florida Research Foundation, Inc. | Biomimetic organic/inorganic composites |
US20060204544A1 (en) | 2002-05-20 | 2006-09-14 | Musculoskeletal Transplant Foundation | Allograft bone composition having a gelatin binder |
CA2494342A1 (en) | 2002-07-31 | 2004-02-12 | Alza Corporation | Injectable depot compositions and uses thereof |
CN1684663A (zh) | 2002-07-31 | 2005-10-19 | 阿尔萨公司 | 可注射的多模式聚合物储库组合物以及其用途 |
CA2500220A1 (en) | 2002-09-30 | 2004-04-08 | Regen Biotech, Inc. | Composition for stimulating bone-formation and bone consolidation |
DE60325511D1 (de) | 2002-11-06 | 2009-02-05 | Alza Corp | Depot-formulierungen mit verzögerter freisetzung |
GB0302738D0 (en) | 2003-02-06 | 2003-03-12 | Advanced Biopolymers As | Composition |
US7217294B2 (en) | 2003-08-20 | 2007-05-15 | Histogenics Corp. | Acellular matrix implants for treatment of articular cartilage, bone or osteochondral defects and injuries and method for use thereof |
GB0403938D0 (en) | 2004-02-21 | 2004-03-24 | West Pharm Serv Drug Res Ltd | Chitosan containing solution |
US20060062768A1 (en) | 2004-09-23 | 2006-03-23 | Olexander Hnojewyj | Biocompatible hydrogel compositions |
ITRM20040539A1 (it) | 2004-11-02 | 2005-02-02 | Mavi Sud S R L | Preparati a base di chitina o suoi derivati per uso cosmetico o medico. |
WO2007127795A2 (en) | 2006-04-25 | 2007-11-08 | Bumgardner Joel D | Chitosan/nanocrystalline hydroxyapatite composite microsphere-based scaffolds |
WO2008064487A1 (en) | 2006-11-30 | 2008-06-05 | Bio Syntech Canada Inc. | Method for in situ solidification of blood-polymer compositions for regenerative medicine and cartilage repair applications |
US8153612B2 (en) | 2006-12-11 | 2012-04-10 | Chi2Gel Ltd. | Injectable chitosan mixtures forming hydrogels |
US7776840B2 (en) | 2007-02-21 | 2010-08-17 | Cutanea Life Sciences, Inc. | Methods of use of biomaterial and injectable implant containing biomaterial |
-
2000
- 2000-12-08 AU AU19792/01A patent/AU1979201A/en not_active Abandoned
- 2000-12-08 US US10/149,052 patent/US20030199615A1/en not_active Abandoned
- 2000-12-08 DE DE60003459T patent/DE60003459T2/de not_active Expired - Lifetime
- 2000-12-08 AT AT00981124T patent/ATE243049T1/de not_active IP Right Cessation
- 2000-12-08 AT AT00982802T patent/ATE247495T1/de not_active IP Right Cessation
- 2000-12-08 AU AU18486/01A patent/AU1848601A/en not_active Abandoned
- 2000-12-08 WO PCT/CA2000/001489 patent/WO2001041821A1/en active IP Right Grant
- 2000-12-08 EP EP00981124A patent/EP1237585B1/de not_active Expired - Lifetime
- 2000-12-08 WO PCT/CA2000/001492 patent/WO2001041822A1/en active IP Right Grant
- 2000-12-08 DE DE60004710T patent/DE60004710T2/de not_active Expired - Lifetime
- 2000-12-08 EP EP00982802A patent/EP1255576B1/de not_active Expired - Lifetime
-
2009
- 2009-10-08 US US12/575,765 patent/US8389467B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20100029549A1 (en) | 2010-02-04 |
EP1255576B1 (de) | 2003-08-20 |
DE60004710T2 (de) | 2004-07-08 |
EP1255576A1 (de) | 2002-11-13 |
WO2001041821A1 (en) | 2001-06-14 |
DE60003459D1 (de) | 2003-07-24 |
WO2001041822A1 (en) | 2001-06-14 |
DE60003459T2 (de) | 2004-05-06 |
US8389467B2 (en) | 2013-03-05 |
AU1848601A (en) | 2001-06-18 |
DE60004710D1 (de) | 2003-09-25 |
EP1237585B1 (de) | 2003-06-18 |
AU1979201A (en) | 2001-06-18 |
US20030199615A1 (en) | 2003-10-23 |
EP1237585A1 (de) | 2002-09-11 |
ATE243049T1 (de) | 2003-07-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE247495T1 (de) | Mineral-polymer hybrid-zusammensetzung | |
AU2001279710A1 (en) | Magnesium-ammonium-phosphate cements, the production of the same and the use thereof | |
US5782971B1 (en) | Calcium phosphate cements comprising amorophous calcium phosphate | |
DE69403439D1 (de) | Tgf-beta zusammensetzung zum herbeiführen von knochenwachstum | |
DE50008321D1 (de) | Zusammensetzung zur implantation in den menschlichen und tierischen körper | |
DE60135841D1 (de) | ||
BR9712036A (pt) | Composição de remineralização. | |
DE69904127D1 (de) | Verfahren zur herstellung eines hydroxyapatit enthaltendes biomaterials, hergestelltes biomaterial und chirurgische oder zahnärtzlische anwendung | |
KR960702294A (ko) | 인산칼슘 수산화인회석 전구체 및 그것의 제조방법 및 사용방법 (calcium phosphate hydroxyapatite precursor and methods for making and using the same) | |
MXPA03011236A (es) | Vehiculos de liberacion de fosfato de calcio para proteinas osteoinductivas. | |
DE59906975D1 (de) | Wässrige reaktive spachtelmassen (i) | |
ATE391519T1 (de) | Strontium-apatit-zement-zubereitungen und deren verwendungen | |
AUPQ660700A0 (en) | Calcium fortification of milk | |
AP9801269A0 (en) | Prostaglandin agonists. | |
PT1259271E (pt) | Processo de preparação de um material pastoso injectável | |
HK1038577A1 (zh) | G-阻斷多糖的用途 | |
ATE157329T1 (de) | Innige mischung von galcium- und phosphat-quellen als hydroxyapatit-vorläufer | |
DE50304127D1 (de) | Pulvergemisch für resorbierbare Calciumphosphat-Biozemente | |
WO2005048877A3 (en) | Calcium phosphate cements comprising an osteoclastogenic agent | |
IL154007A0 (en) | Soluble fertilizer compositions comprising calcium and/or magnesium phosphates | |
CA2176535A1 (en) | Peat based compositions | |
EP1394132A3 (de) | Neue Calciumphosphatzementzusammensetzung und ihr Herstellungsverfahren | |
AR019759A1 (es) | Un cemento biologico | |
TR200101158T1 (tr) | Yüzeyi modifiye edilmiş manganez sülfit, bunu üretme yöntemi ve kullanılması. | |
KR970001255A (ko) | 고기능성 요업원료의 합성 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |