ATE240950T1 - Dihydrobenzopyran und ähnliche verbindungen verwendbar als antientzündungsmittel - Google Patents

Dihydrobenzopyran und ähnliche verbindungen verwendbar als antientzündungsmittel

Info

Publication number
ATE240950T1
ATE240950T1 AT97929866T AT97929866T ATE240950T1 AT E240950 T1 ATE240950 T1 AT E240950T1 AT 97929866 T AT97929866 T AT 97929866T AT 97929866 T AT97929866 T AT 97929866T AT E240950 T1 ATE240950 T1 AT E240950T1
Authority
AT
Austria
Prior art keywords
pct
branched
dihydrobenzopyran
inflammatory agents
similar compounds
Prior art date
Application number
AT97929866T
Other languages
English (en)
Inventor
John Michael Janusz
Carl Randolph Johnson
Chandrawansha Banda Senanayake
Original Assignee
Univ Vanderbilt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Vanderbilt filed Critical Univ Vanderbilt
Application granted granted Critical
Publication of ATE240950T1 publication Critical patent/ATE240950T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
AT97929866T 1996-06-07 1997-06-06 Dihydrobenzopyran und ähnliche verbindungen verwendbar als antientzündungsmittel ATE240950T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1941496P 1996-06-07 1996-06-07
PCT/US1997/009945 WO1997046548A1 (en) 1996-06-07 1997-06-06 Dihydrobenzopyran and related compounds useful as anti-inflammatory agents

Publications (1)

Publication Number Publication Date
ATE240950T1 true ATE240950T1 (de) 2003-06-15

Family

ID=21793077

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97929866T ATE240950T1 (de) 1996-06-07 1997-06-06 Dihydrobenzopyran und ähnliche verbindungen verwendbar als antientzündungsmittel

Country Status (21)

Country Link
US (1) US6110960A (de)
EP (1) EP0907646B1 (de)
JP (1) JP3454832B2 (de)
KR (1) KR100314986B1 (de)
CN (1) CN1106394C (de)
AT (1) ATE240950T1 (de)
AU (1) AU733669B2 (de)
BR (1) BR9709556A (de)
CA (1) CA2256718C (de)
CZ (1) CZ398598A3 (de)
DE (1) DE69722202T2 (de)
DK (1) DK0907646T3 (de)
ES (1) ES2199362T3 (de)
HU (1) HUP0101131A3 (de)
IL (1) IL127379A0 (de)
NO (1) NO985679L (de)
PL (1) PL330408A1 (de)
RU (1) RU2156762C1 (de)
SK (1) SK167798A3 (de)
TR (1) TR199802538T2 (de)
WO (1) WO1997046548A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR199802538T2 (xx) * 1996-06-07 2001-01-22 The Procter & Gamble Company �ltihaplanmaya kar�� maddeler olarak yararl� dihidrobenzopiran ve ili�kili bile�ikler.
US6077850A (en) * 1997-04-21 2000-06-20 G.D. Searle & Co. Substituted benzopyran analogs for the treatment of inflammation
US6586460B1 (en) 2001-04-02 2003-07-01 The Board Of Regents For Oklahoma State University Heteroarotinoids containing urea or thiourea linker
US20030114416A1 (en) * 2001-08-14 2003-06-19 Pharmacia Corporation Method and compositions for the treatment and prevention of pain and inflammation with a cyclooxygenase-2 selective inhibitor and chondroitin sulfate
US20050101563A1 (en) * 2001-08-14 2005-05-12 Pharmacia Corporation Method and compositions for the treatment and prevention of pain and inflammation
US20030220374A1 (en) * 2002-01-14 2003-11-27 Pharmacia Corporation Compositions and methods of treatment involving peroxisome proliferator-activated receptor-gamma agonists and cyclooxygenase-2 selective inhibitors
US20030212138A1 (en) * 2002-01-14 2003-11-13 Pharmacia Corporation Combinations of peroxisome proliferator-activated receptor-alpha agonists and cyclooxygenase-2 selective inhibitors and therapeutic uses therefor
MXPA04010186A (es) * 2002-04-18 2005-02-03 Pharmacia Corp Monoterapia para el tratamiento de la enfermedad de parkinson con inhibidor (es) de la ciclooxigenasa-2 (cox 2).
JP2005528403A (ja) * 2002-04-18 2005-09-22 ファルマシア・コーポレーション シクロオキシゲナーゼ−２（ｃｏｘ２）阻害薬によるパーキンソン病処置のための併用療法
US20040147581A1 (en) * 2002-11-18 2004-07-29 Pharmacia Corporation Method of using a Cox-2 inhibitor and a 5-HT1A receptor modulator as a combination therapy
US20040204411A1 (en) * 2002-12-17 2004-10-14 Pharmacia Corporation Method for the treatment, prevention, or inhibition of a CNS disorder and/or pain and inflammation using a combination of reboxetine and a cyclooxygenase-2 selective inhibitor and compositions thereof
US20040235925A1 (en) * 2002-12-17 2004-11-25 Pharmacia Corporation Method for the treatment, prevention, or inhibition of a CNS disorder and/or pain and inflammation using a combination of duloxetine, venlafaxine or atomoxetine and a cyclooxygenase-2 selective inhibitor and compositions thereof
ES2335849B1 (es) * 2008-10-03 2011-03-22 Consejo Superior De Investigaciones Cientificas (Csic) Derivados de cromano y sus usos como inhibidores de la actividad de las proteinas desacoplantes.

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0026593A1 (de) * 1979-09-15 1981-04-08 Pfizer Limited Bicyclische Keto- und Aminosäuren, Ester und Amide und deren pharmazeutische Zusammensetzungen
JPS5829782A (ja) * 1981-08-12 1983-02-22 Nippon Zoki Pharmaceut Co Ltd 新規複素環化合物、その製法及び該化合物を含有する医薬組成物
US4680404A (en) * 1983-01-13 1987-07-14 Pfizer Inc. Benzopyrans
LU86351A1 (fr) * 1986-03-12 1987-11-11 Oreal Composes benzopyrannyl et benzothiopyrannyl benzoiques,leur procede de preparation et leur utilisation en cosmetique et en medecine humaine et veterinaire
WO1994004524A1 (en) * 1992-08-18 1994-03-03 Idemitsu Kosan Co., Ltd. Cyclohexanedione derivative
US5466861A (en) * 1992-11-25 1995-11-14 Sri International Bridged bicyclic aromatic compounds and their use in modulating gene expression of retinoid receptors
GB9316111D0 (en) * 1993-08-04 1993-09-22 Pfizer Ltd Benzopyrans
US5675024A (en) * 1995-11-22 1997-10-07 Allergan Aryl or heteroaryl amides of tetrahydronaphthalene, chroman, thiochroman and 1,2,3,4,-tetrahydroquinoline carboxylic acids, having an electron withdrawing substituent in the aromatic or heteroaromatic moiety, having retinoid-like biological activity
TR199802538T2 (xx) * 1996-06-07 2001-01-22 The Procter & Gamble Company �ltihaplanmaya kar�� maddeler olarak yararl� dihidrobenzopiran ve ili�kili bile�ikler.
US5919817A (en) * 1996-10-28 1999-07-06 Novo Nordisk A/S Cis-3, 4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes

Also Published As

Publication number Publication date
DE69722202T2 (de) 2004-04-01
US6110960A (en) 2000-08-29
CN1230955A (zh) 1999-10-06
JP3454832B2 (ja) 2003-10-06
DE69722202D1 (de) 2003-06-26
CA2256718A1 (en) 1997-12-11
EP0907646A1 (de) 1999-04-14
DK0907646T3 (da) 2003-09-15
HUP0101131A2 (hu) 2001-12-28
AU733669B2 (en) 2001-05-24
RU2156762C1 (ru) 2000-09-27
CN1106394C (zh) 2003-04-23
PL330408A1 (en) 1999-05-10
BR9709556A (pt) 1999-08-10
EP0907646B1 (de) 2003-05-21
SK167798A3 (en) 2000-02-14
TR199802538T2 (xx) 2001-01-22
ES2199362T3 (es) 2004-02-16
HUP0101131A3 (en) 2002-04-29
IL127379A0 (en) 1999-10-28
CA2256718C (en) 2004-09-21
NO985679D0 (no) 1998-12-04
CZ398598A3 (cs) 1999-07-14
KR100314986B1 (ko) 2002-01-12
AU3382697A (en) 1998-01-05
JP2000501417A (ja) 2000-02-08
WO1997046548A1 (en) 1997-12-11
NO985679L (no) 1999-02-05
KR20000016427A (ko) 2000-03-25

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties