DK0907646T3 - Dihydrobenzopyren og lignende forbindelser anvendelige som middel mod betændelse - Google Patents

Dihydrobenzopyren og lignende forbindelser anvendelige som middel mod betændelse

Info

Publication number
DK0907646T3
DK0907646T3 DK97929866T DK97929866T DK0907646T3 DK 0907646 T3 DK0907646 T3 DK 0907646T3 DK 97929866 T DK97929866 T DK 97929866T DK 97929866 T DK97929866 T DK 97929866T DK 0907646 T3 DK0907646 T3 DK 0907646T3
Authority
DK
Denmark
Prior art keywords
pct
branched
dihydrobenzopyrene
useful
inflammatory agents
Prior art date
Application number
DK97929866T
Other languages
Danish (da)
English (en)
Inventor
John Michael Janusz
Carl Randolph Johnson
Chandrawansha Banda Senanayake
Original Assignee
Univ Vanderbilt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Vanderbilt filed Critical Univ Vanderbilt
Application granted granted Critical
Publication of DK0907646T3 publication Critical patent/DK0907646T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Luminescent Compositions (AREA)
DK97929866T 1996-06-07 1997-06-06 Dihydrobenzopyren og lignende forbindelser anvendelige som middel mod betændelse DK0907646T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1941496P 1996-06-07 1996-06-07
PCT/US1997/009945 WO1997046548A1 (en) 1996-06-07 1997-06-06 Dihydrobenzopyran and related compounds useful as anti-inflammatory agents

Publications (1)

Publication Number Publication Date
DK0907646T3 true DK0907646T3 (da) 2003-09-15

Family

ID=21793077

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97929866T DK0907646T3 (da) 1996-06-07 1997-06-06 Dihydrobenzopyren og lignende forbindelser anvendelige som middel mod betændelse

Country Status (21)

Country Link
US (1) US6110960A (de)
EP (1) EP0907646B1 (de)
JP (1) JP3454832B2 (de)
KR (1) KR100314986B1 (de)
CN (1) CN1106394C (de)
AT (1) ATE240950T1 (de)
AU (1) AU733669B2 (de)
BR (1) BR9709556A (de)
CA (1) CA2256718C (de)
CZ (1) CZ398598A3 (de)
DE (1) DE69722202T2 (de)
DK (1) DK0907646T3 (de)
ES (1) ES2199362T3 (de)
HU (1) HUP0101131A3 (de)
IL (1) IL127379A0 (de)
NO (1) NO985679L (de)
PL (1) PL330408A1 (de)
RU (1) RU2156762C1 (de)
SK (1) SK167798A3 (de)
TR (1) TR199802538T2 (de)
WO (1) WO1997046548A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2156762C1 (ru) * 1996-06-07 2000-09-27 Дзе Проктер Энд Гэмбл Компани Производные дигидробензопирана, фармацевтическая композиция на их основе и способы лечения
US6077850A (en) * 1997-04-21 2000-06-20 G.D. Searle & Co. Substituted benzopyran analogs for the treatment of inflammation
US6586460B1 (en) 2001-04-02 2003-07-01 The Board Of Regents For Oklahoma State University Heteroarotinoids containing urea or thiourea linker
US20030114416A1 (en) * 2001-08-14 2003-06-19 Pharmacia Corporation Method and compositions for the treatment and prevention of pain and inflammation with a cyclooxygenase-2 selective inhibitor and chondroitin sulfate
US20050101563A1 (en) * 2001-08-14 2005-05-12 Pharmacia Corporation Method and compositions for the treatment and prevention of pain and inflammation
US20030212138A1 (en) * 2002-01-14 2003-11-13 Pharmacia Corporation Combinations of peroxisome proliferator-activated receptor-alpha agonists and cyclooxygenase-2 selective inhibitors and therapeutic uses therefor
US20030220374A1 (en) * 2002-01-14 2003-11-27 Pharmacia Corporation Compositions and methods of treatment involving peroxisome proliferator-activated receptor-gamma agonists and cyclooxygenase-2 selective inhibitors
CA2481934A1 (en) * 2002-04-18 2003-10-30 Pharmacia Corporation Combinations of cox-2 inhibitors and other agents for the treatment of parkinson's disease
BR0309337A (pt) * 2002-04-18 2005-02-15 Pharmacia Corp Monoterapia para o tratamento de doença de parkinson com inibidores de ciclooxigenase-2 (cox2)
US20040147581A1 (en) * 2002-11-18 2004-07-29 Pharmacia Corporation Method of using a Cox-2 inhibitor and a 5-HT1A receptor modulator as a combination therapy
US20040235925A1 (en) * 2002-12-17 2004-11-25 Pharmacia Corporation Method for the treatment, prevention, or inhibition of a CNS disorder and/or pain and inflammation using a combination of duloxetine, venlafaxine or atomoxetine and a cyclooxygenase-2 selective inhibitor and compositions thereof
US20040204411A1 (en) * 2002-12-17 2004-10-14 Pharmacia Corporation Method for the treatment, prevention, or inhibition of a CNS disorder and/or pain and inflammation using a combination of reboxetine and a cyclooxygenase-2 selective inhibitor and compositions thereof
ES2335849B1 (es) * 2008-10-03 2011-03-22 Consejo Superior De Investigaciones Cientificas (Csic) Derivados de cromano y sus usos como inhibidores de la actividad de las proteinas desacoplantes.

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0026593A1 (de) * 1979-09-15 1981-04-08 Pfizer Limited Bicyclische Keto- und Aminosäuren, Ester und Amide und deren pharmazeutische Zusammensetzungen
JPS5829782A (ja) * 1981-08-12 1983-02-22 Nippon Zoki Pharmaceut Co Ltd 新規複素環化合物、その製法及び該化合物を含有する医薬組成物
US4680404A (en) * 1983-01-13 1987-07-14 Pfizer Inc. Benzopyrans
LU86351A1 (fr) * 1986-03-12 1987-11-11 Oreal Composes benzopyrannyl et benzothiopyrannyl benzoiques,leur procede de preparation et leur utilisation en cosmetique et en medecine humaine et veterinaire
WO1994004524A1 (en) * 1992-08-18 1994-03-03 Idemitsu Kosan Co., Ltd. Cyclohexanedione derivative
US5466861A (en) * 1992-11-25 1995-11-14 Sri International Bridged bicyclic aromatic compounds and their use in modulating gene expression of retinoid receptors
GB9316111D0 (en) * 1993-08-04 1993-09-22 Pfizer Ltd Benzopyrans
US5675024A (en) * 1995-11-22 1997-10-07 Allergan Aryl or heteroaryl amides of tetrahydronaphthalene, chroman, thiochroman and 1,2,3,4,-tetrahydroquinoline carboxylic acids, having an electron withdrawing substituent in the aromatic or heteroaromatic moiety, having retinoid-like biological activity
RU2156762C1 (ru) * 1996-06-07 2000-09-27 Дзе Проктер Энд Гэмбл Компани Производные дигидробензопирана, фармацевтическая композиция на их основе и способы лечения
US5919817A (en) * 1996-10-28 1999-07-06 Novo Nordisk A/S Cis-3, 4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes

Also Published As

Publication number Publication date
WO1997046548A1 (en) 1997-12-11
SK167798A3 (en) 2000-02-14
TR199802538T2 (xx) 2001-01-22
CN1230955A (zh) 1999-10-06
RU2156762C1 (ru) 2000-09-27
JP2000501417A (ja) 2000-02-08
DE69722202D1 (de) 2003-06-26
NO985679D0 (no) 1998-12-04
CA2256718A1 (en) 1997-12-11
ATE240950T1 (de) 2003-06-15
KR100314986B1 (ko) 2002-01-12
DE69722202T2 (de) 2004-04-01
AU3382697A (en) 1998-01-05
PL330408A1 (en) 1999-05-10
KR20000016427A (ko) 2000-03-25
IL127379A0 (en) 1999-10-28
JP3454832B2 (ja) 2003-10-06
NO985679L (no) 1999-02-05
HUP0101131A2 (hu) 2001-12-28
BR9709556A (pt) 1999-08-10
CA2256718C (en) 2004-09-21
ES2199362T3 (es) 2004-02-16
US6110960A (en) 2000-08-29
EP0907646B1 (de) 2003-05-21
EP0907646A1 (de) 1999-04-14
HUP0101131A3 (en) 2002-04-29
CZ398598A3 (cs) 1999-07-14
CN1106394C (zh) 2003-04-23
AU733669B2 (en) 2001-05-24

Similar Documents

Publication Publication Date Title
NO983529D0 (no) Dihydrobenzofuran og relaterte forbindelser anvendelig som anti-inflammatoriske midler
MX9701819A (es) Dihidrobenzofurano y compuestos relacionados, utiles como agentes antiiflamatorios.
DK0907646T3 (da) Dihydrobenzopyren og lignende forbindelser anvendelige som middel mod betændelse
NO983525L (no) Dihydrobenzofuran og relaterte forbindelser anvendelig som anti-inflammatoriske midler
CA2196054A1 (en) Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
NO983531D0 (no) Dihydrobenzofuranforbindelser anvendelig som antiinflammatoriske midler
DK0904270T3 (da) Dihydrobenzofuran og beslægtede forbindelser anvendelige som antiinflammatoriske midler
MX9700726A (es) Dihidrobenzofurano y compuestos relacionados, utiles como agentes antiinflamatorios.
MX9806247A (es) Dihidrobenzofurano y compuestos relacionados utiles como agentes antiinflamatorios.
NO983528D0 (no) Dihydrobenzofuran og relaterte forbindelser anvendelig som anti-inflammatoriske midler
CA2244245A1 (en) Dihydrobenzofuran and related compounds useful as anti-inflammatory agents