CA2244245A1 - Dihydrobenzofuran and related compounds useful as anti-inflammatory agents - Google Patents
Dihydrobenzofuran and related compounds useful as anti-inflammatory agentsInfo
- Publication number
- CA2244245A1 CA2244245A1 CA002244245A CA2244245A CA2244245A1 CA 2244245 A1 CA2244245 A1 CA 2244245A1 CA 002244245 A CA002244245 A CA 002244245A CA 2244245 A CA2244245 A CA 2244245A CA 2244245 A1 CA2244245 A1 CA 2244245A1
- Authority
- CA
- Canada
- Prior art keywords
- hydrogen
- dihydrobenzofuran
- atoms
- inflammatory agents
- compounds useful
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
A compound having structure (I) wherein (a) n is from 1 to about 3; (b) X is selected from the group consisting of O, S, SO, or SO2; (c) Y
is independently hydrogen or straight, branched or cyclic alkyl having from 1 to about 4 carbon atoms, or the Y's are bonded together to form an alkanyl ring having from about 3 to about 7 atoms; (d) Z is hydrogen or straight, branched or cyclic alkyl having from 3 to about 10 atoms other than hydrogen; (e) W is O or S; and (f) Het is a heteroaryl group comprising one or more rings each ring containing from about 5 to about 6 atoms other than hydrogen and wherein the group contains at least one heteroatom selected from O, N, or S. Pharmaceutical compositions comprising such compounds, and methods of treating inflammation or pain using such compounds.
is independently hydrogen or straight, branched or cyclic alkyl having from 1 to about 4 carbon atoms, or the Y's are bonded together to form an alkanyl ring having from about 3 to about 7 atoms; (d) Z is hydrogen or straight, branched or cyclic alkyl having from 3 to about 10 atoms other than hydrogen; (e) W is O or S; and (f) Het is a heteroaryl group comprising one or more rings each ring containing from about 5 to about 6 atoms other than hydrogen and wherein the group contains at least one heteroatom selected from O, N, or S. Pharmaceutical compositions comprising such compounds, and methods of treating inflammation or pain using such compounds.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/595,113 US5750543A (en) | 1996-02-01 | 1996-02-01 | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
| US08/595,113 | 1996-02-01 | ||
| PCT/US1997/001310 WO1997028144A1 (en) | 1996-02-01 | 1997-01-30 | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2244245A1 true CA2244245A1 (en) | 1997-08-07 |
| CA2244245C CA2244245C (en) | 2005-11-29 |
Family
ID=35520643
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002244245A Expired - Fee Related CA2244245C (en) | 1996-02-01 | 1997-01-30 | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA2244245C (en) |
-
1997
- 1997-01-30 CA CA002244245A patent/CA2244245C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2244245C (en) | 2005-11-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |