ATE234078T1 - Pharmazeutische omeprazol-formulierung - Google Patents

Pharmazeutische omeprazol-formulierung

Info

Publication number
ATE234078T1
ATE234078T1 AT98924700T AT98924700T ATE234078T1 AT E234078 T1 ATE234078 T1 AT E234078T1 AT 98924700 T AT98924700 T AT 98924700T AT 98924700 T AT98924700 T AT 98924700T AT E234078 T1 ATE234078 T1 AT E234078T1
Authority
AT
Austria
Prior art keywords
pharmaceutical
omeprazole formulation
omeprazole
formulation
pharmaceutical omeprazole
Prior art date
Application number
AT98924700T
Other languages
English (en)
Inventor
Magnus Erickson
Lars Josefsson
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20407122&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE234078(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE234078T1 publication Critical patent/ATE234078T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
AT98924700T 1997-05-28 1998-05-18 Pharmazeutische omeprazol-formulierung ATE234078T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9702000A SE9702000D0 (sv) 1997-05-28 1997-05-28 New pharmaceutical formulation
PCT/SE1998/000922 WO1998053803A1 (en) 1997-05-28 1998-05-18 Pharmaceutical formulation of omeprazole

Publications (1)

Publication Number Publication Date
ATE234078T1 true ATE234078T1 (de) 2003-03-15

Family

ID=20407122

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98924700T ATE234078T1 (de) 1997-05-28 1998-05-18 Pharmazeutische omeprazol-formulierung

Country Status (41)

Country Link
US (1) US6090827A (de)
EP (1) EP0984773B1 (de)
JP (1) JP4649001B2 (de)
KR (1) KR100540721B1 (de)
CN (1) CN1123338C (de)
AR (1) AR012698A1 (de)
AT (1) ATE234078T1 (de)
AU (1) AU722879B2 (de)
BR (1) BR9809484A (de)
CA (1) CA2290531C (de)
CZ (1) CZ298972B6 (de)
DE (1) DE69812089T2 (de)
DK (1) DK0984773T3 (de)
DZ (1) DZ2494A1 (de)
EE (1) EE03903B1 (de)
EG (1) EG24044A (de)
ES (1) ES2195342T3 (de)
HK (1) HK1025744A1 (de)
HR (1) HRP980260B1 (de)
HU (1) HU229154B1 (de)
ID (1) ID24654A (de)
IL (1) IL132895A0 (de)
IS (1) IS2856B (de)
MA (1) MA26497A1 (de)
MY (1) MY122298A (de)
NO (1) NO328100B1 (de)
NZ (1) NZ500886A (de)
PL (1) PL194634B1 (de)
PT (1) PT984773E (de)
RS (1) RS49629B (de)
RU (1) RU2207121C2 (de)
SA (1) SA98190304B1 (de)
SE (1) SE9702000D0 (de)
SI (1) SI0984773T1 (de)
SK (1) SK286625B6 (de)
TN (1) TNSN98068A1 (de)
TR (1) TR199902890T2 (de)
TW (1) TW575435B (de)
UA (1) UA71541C2 (de)
WO (1) WO1998053803A1 (de)
ZA (1) ZA984178B (de)

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US6645988B2 (en) * 1996-01-04 2003-11-11 Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US6699885B2 (en) * 1996-01-04 2004-03-02 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and methods of using same
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US6096340A (en) 1997-11-14 2000-08-01 Andrx Pharmaceuticals, Inc. Omeprazole formulation
US6174548B1 (en) * 1998-08-28 2001-01-16 Andrx Pharmaceuticals, Inc. Omeprazole formulation
CA2298823C (en) * 1998-04-20 2011-06-07 Eisai Co., Ltd. Stabilized composition comprising a benzimidazole type compound
SE9803772D0 (sv) * 1998-11-05 1998-11-05 Astra Ab Pharmaceutical formulation
SE9902386D0 (sv) * 1999-06-22 1999-06-22 Astra Ab New formulation
US6245913B1 (en) 1999-06-30 2001-06-12 Wockhardt Europe Limited Synthetic procedure for 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-IH-benzimidazole hydrochloride and its conversion to omeprazole
ES2168043B1 (es) 1999-09-13 2003-04-01 Esteve Labor Dr Forma farmaceutica solida oral de liberacion modificada que contiene un compuesto de bencimidazol labil en medio acido.
JP4081273B2 (ja) 1999-10-20 2008-04-23 エーザイ・アール・アンド・ディー・マネジメント株式会社 ベンズイミダゾール系化合物安定化方法
US20040092511A1 (en) * 1999-12-10 2004-05-13 Billstein Stephan Anthony Pharmaceutical combinations and their use in treating gastrointestinal and abdominal viscera disorders
US20020192299A1 (en) * 2000-12-28 2002-12-19 Rajneesh Taneja Pharmaceutical compositions of a non-enteric coated proton pump inhibitor with a carbonate salt and bicarbonate salt combination
JP2002234842A (ja) * 2001-02-09 2002-08-23 Kyowa Yakuhin Kogyo Kk 内服腸溶性製剤
US20040006111A1 (en) * 2002-01-25 2004-01-08 Kenneth Widder Transmucosal delivery of proton pump inhibitors
US20040082618A1 (en) * 2002-07-03 2004-04-29 Rajneesh Taneja Liquid dosage forms of acid labile drugs
FR2843121B3 (fr) 2002-08-02 2004-09-10 Rhodia Chimie Sa Agent ignifugeant, procede de preparation et l'utilisation de cet agent
US20070243251A1 (en) * 2002-12-20 2007-10-18 Rajneesh Taneja Dosage Forms Containing A PPI, NSAID, and Buffer
US20040121004A1 (en) * 2002-12-20 2004-06-24 Rajneesh Taneja Dosage forms containing a PPI, NSAID, and buffer
US20040146558A1 (en) * 2003-01-28 2004-07-29 Kyowa Pharmaceutical Co., Ltd. Oral enteric-coated preparation
CN1761465B (zh) * 2003-01-29 2010-10-13 武田药品工业株式会社 制备被覆制剂的方法
PL377403A1 (pl) * 2003-01-29 2006-02-06 Takeda Pharmaceutical Company Limited Sposób wytwarzania preparatu powlekanego
JP4567340B2 (ja) * 2003-01-29 2010-10-20 武田薬品工業株式会社 被覆製剤の製造方法
US20040248942A1 (en) * 2003-02-20 2004-12-09 Bonnie Hepburn Novel formulation, omeprazole antacid complex-immediate release for rapid and sustained suppression of gastric acid
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US20070292498A1 (en) * 2003-11-05 2007-12-20 Warren Hall Combinations of proton pump inhibitors, sleep aids, buffers and pain relievers
CN1311824C (zh) * 2004-04-21 2007-04-25 常州市第四制药厂有限公司 奥美拉唑肠溶微粒制剂及制备方法
US8906940B2 (en) 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8815916B2 (en) * 2004-05-25 2014-08-26 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
EP1747800B1 (de) * 2005-07-29 2009-03-18 Rottapharm S.p.A. Kombination aus Itriglumid und PPI zur Behandlung von gastrointestinalen- und assozierten Krankheiten
CA2654402A1 (en) * 2006-06-01 2007-12-06 Adel Penhasi Multiple unit pharmaceutical formulation
KR101436516B1 (ko) * 2007-07-23 2014-09-02 주식회사태평양제약 코팅된 펠렛을 함유하는 현탁정 및 이의 제조방법
CN101808622A (zh) * 2007-09-28 2010-08-18 西梯茜生命工学股份有限公司 含有埃索美拉唑的药物组合物
CN101980701A (zh) * 2008-03-28 2011-02-23 菲尔若国际公司 用于预防心血管疾病的胶囊
PL2334378T3 (pl) 2008-08-19 2014-09-30 Xenoport Inc Proleki wodorofumaranu metylu, ich kompozycje farmaceutyczne i sposoby zastosowania
AU2013305684B2 (en) 2012-08-22 2016-11-24 Xenoport, Inc. Oral dosage forms of methyl hydrogen fumarate and prodrugs thereof
US10945984B2 (en) 2012-08-22 2021-03-16 Arbor Pharmaceuticals, Llc Methods of administering monomethyl fumarate and prodrugs thereof having reduced side effects
CN102961356A (zh) * 2012-12-11 2013-03-13 山西云鹏制药有限公司 一种含奥美拉唑的蓝色肠溶片剂的制备方法
US10179118B2 (en) 2013-03-24 2019-01-15 Arbor Pharmaceuticals, Llc Pharmaceutical compositions of dimethyl fumarate
JP2016534133A (ja) 2013-09-06 2016-11-04 ゼノポート，インコーポレイティド （ｎ，ｎ−ジエチルカルバモイル）メチル メチル（２ｅ）ブト−２−エン−１，４−ジオエートの結晶形態、その合成方法及び使用
US20150079180A1 (en) * 2013-09-18 2015-03-19 Xenoport, Inc. Nanoparticle compositions of dimethyl fumarate
US9999672B2 (en) 2014-03-24 2018-06-19 Xenoport, Inc. Pharmaceutical compositions of fumaric acid esters
WO2016174664A1 (en) 2015-04-29 2016-11-03 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
WO2021153525A1 (ja) 2020-01-27 2021-08-05 東和薬品株式会社 エソメプラゾール経口製剤およびその製造方法
KR102432084B1 (ko) 2021-11-16 2022-08-12 알리코제약(주) S-오메프라졸을 함유하는 안정성이 개선되고 소형화된 정제
WO2024075017A1 (en) 2022-10-04 2024-04-11 Zabirnyk Arsenii Inhibition of aortic valve calcification

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SE8301182D0 (sv) * 1983-03-04 1983-03-04 Haessle Ab Novel compounds
GB2189698A (en) * 1986-04-30 1987-11-04 Haessle Ab Coated omeprazole tablets
JPH05255088A (ja) * 1991-11-05 1993-10-05 Yoshitomi Pharmaceut Ind Ltd 抗潰瘍剤含有製剤
JP2669446B2 (ja) * 1992-03-23 1997-10-27 信越化学工業株式会社 医薬品コーティング液用原料粉粒体
JPH0733659A (ja) * 1992-07-17 1995-02-03 Yoshitomi Pharmaceut Ind Ltd 抗潰瘍剤含有製剤
SE9301830D0 (sv) * 1993-05-28 1993-05-28 Ab Astra New compounds
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SE9500422D0 (sv) * 1995-02-06 1995-02-06 Astra Ab New oral pharmaceutical dosage forms

Also Published As

Publication number Publication date
EP0984773A1 (de) 2000-03-15
AU7680398A (en) 1998-12-30
RS49629B (sr) 2007-08-03
SA98190304B1 (ar) 2006-10-11
EG24044A (en) 2008-04-13
UA71541C2 (uk) 2004-12-15
IS2856B (is) 2013-11-15
DK0984773T3 (da) 2003-07-07
SK286625B6 (sk) 2009-02-05
HRP980260A2 (en) 1999-02-28
EE03903B1 (et) 2002-12-16
EP0984773B1 (de) 2003-03-12
JP4649001B2 (ja) 2011-03-09
BR9809484A (pt) 2000-06-20
CA2290531C (en) 2006-12-12
IL132895A0 (en) 2001-03-19
CN1258217A (zh) 2000-06-28
DZ2494A1 (fr) 2003-01-25
NO995809D0 (no) 1999-11-26
RU2207121C2 (ru) 2003-06-27
HRP980260B1 (en) 2003-10-31
MA26497A1 (fr) 2004-12-20
TR199902890T2 (xx) 2000-02-21
JP2002500665A (ja) 2002-01-08
IS5245A (is) 1999-11-11
SK159099A3 (en) 2000-06-12
CN1123338C (zh) 2003-10-08
HUP0002182A2 (hu) 2002-05-29
PL337237A1 (en) 2000-08-14
HUP0002182A3 (en) 2003-02-28
HU229154B1 (en) 2013-09-30
ES2195342T3 (es) 2003-12-01
TW575435B (en) 2004-02-11
DE69812089D1 (de) 2003-04-17
PT984773E (pt) 2003-07-31
NO328100B1 (no) 2009-12-07
US6090827A (en) 2000-07-18
DE69812089T2 (de) 2004-03-04
CZ420299A3 (cs) 2000-05-17
AU722879B2 (en) 2000-08-10
KR20010013104A (ko) 2001-02-26
SI0984773T1 (en) 2003-10-31
NZ500886A (en) 2001-11-30
CA2290531A1 (en) 1998-12-03
YU60899A (sh) 2002-06-19
NO995809L (no) 2000-01-28
TNSN98068A1 (fr) 2005-03-15
SE9702000D0 (sv) 1997-05-28
ID24654A (id) 2000-07-27
HK1025744A1 (en) 2000-11-24
WO1998053803A1 (en) 1998-12-03
PL194634B1 (pl) 2007-06-29
EE9900540A (et) 2000-06-15
AR012698A1 (es) 2000-11-08
CZ298972B6 (cs) 2008-03-26
ZA984178B (en) 1998-11-30
KR100540721B1 (ko) 2006-01-10
MY122298A (en) 2006-04-29

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