ATE221890T1 - Verfahren zur selektiven herstellung von z- isomeren von 3-(2-substituiertes vinyl)cephalosporinen - Google Patents

Verfahren zur selektiven herstellung von z- isomeren von 3-(2-substituiertes vinyl)cephalosporinen

Info

Publication number
ATE221890T1
ATE221890T1 AT98929666T AT98929666T ATE221890T1 AT E221890 T1 ATE221890 T1 AT E221890T1 AT 98929666 T AT98929666 T AT 98929666T AT 98929666 T AT98929666 T AT 98929666T AT E221890 T1 ATE221890 T1 AT E221890T1
Authority
AT
Austria
Prior art keywords
isomers
cephalosporines
substituted vinyl
selective production
likeü
Prior art date
Application number
AT98929666T
Other languages
English (en)
Inventor
Yumiko Okada
Masamichi Sukegawa
Tatsuo Watanabe
Hiroyuki Iwasawa
Yasushi Murai
Katsuharu Iinuma
Original Assignee
Meiji Seika Kaisha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meiji Seika Kaisha filed Critical Meiji Seika Kaisha
Application granted granted Critical
Publication of ATE221890T1 publication Critical patent/ATE221890T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
AT98929666T 1997-06-24 1998-06-24 Verfahren zur selektiven herstellung von z- isomeren von 3-(2-substituiertes vinyl)cephalosporinen ATE221890T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP16694897 1997-06-24
PCT/JP1998/002820 WO1998058932A1 (fr) 1997-06-24 1998-06-24 Procede pour l'elaboration selective de z-isomeres de 3-(vinyl substitue en 2) cephalosporines

Publications (1)

Publication Number Publication Date
ATE221890T1 true ATE221890T1 (de) 2002-08-15

Family

ID=15840609

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98929666T ATE221890T1 (de) 1997-06-24 1998-06-24 Verfahren zur selektiven herstellung von z- isomeren von 3-(2-substituiertes vinyl)cephalosporinen

Country Status (24)

Country Link
US (1) US6288223B1 (de)
EP (1) EP1016665B1 (de)
JP (1) JP3713282B2 (de)
KR (1) KR100515273B1 (de)
CN (1) CN1107679C (de)
AT (1) ATE221890T1 (de)
AU (1) AU731265B2 (de)
BR (1) BR9810313B1 (de)
CA (1) CA2294178C (de)
CZ (1) CZ295599B6 (de)
DE (1) DE69807093T2 (de)
EA (1) EA002449B1 (de)
ES (1) ES2182330T3 (de)
HU (1) HU228767B1 (de)
ID (1) ID24210A (de)
IL (1) IL133681A (de)
NZ (1) NZ502234A (de)
PL (1) PL193367B1 (de)
PT (1) PT1016665E (de)
RO (1) RO120261B1 (de)
SK (1) SK283525B6 (de)
TR (1) TR200000310T2 (de)
UA (1) UA55463C2 (de)
WO (1) WO1998058932A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4157177B2 (ja) * 1997-06-04 2008-09-24 大塚化学ホールディングス株式会社 ３−アルケニルセフェム化合物の製造法
WO2005003141A2 (en) * 2003-07-04 2005-01-13 Orchid Chemicals & Pharmaceuticals Ltd An improved process for the preparation of cefditoren
EP1660505A2 (de) * 2003-08-14 2006-05-31 Ranbaxy Laboratories Limited Verfahren zur selektiven herstellung des z-isomers von cefditoren und dessen pharmazeutisch unbedenklichen salzen und estern
WO2005100369A1 (en) * 2004-04-13 2005-10-27 Ranbaxy Laboratories Limited Depletion of e-isomers in preparation of z-enriched 3-(2-substituted vinyl) cephalosporins
WO2005100367A1 (en) * 2004-04-13 2005-10-27 Ranbaxy Laboratories Limited Intermediates useful in the synthesis of 3-(2-substituted vinyl) cephalosporins
JP4064948B2 (ja) * 2004-06-04 2008-03-19 明治製菓株式会社 ３−アルケニルセフェム化合物及び製造方法
JP4046708B2 (ja) * 2004-06-04 2008-02-13 明治製菓株式会社 ３−アルケニルセフェム化合物の製造方法
TW200619222A (en) * 2004-09-02 2006-06-16 Rohm & Haas Elect Mat Method for making organometallic compounds
JP2006096679A (ja) * 2004-09-28 2006-04-13 Meiji Seika Kaisha Ltd セファロスポリン化合物の製造方法
CN101665499A (zh) * 2008-09-01 2010-03-10 日本化学工业株式会社 头孢烯化合物的制造方法
EP2520578A1 (de) 2011-05-06 2012-11-07 Lupin Limited Verfahren zur Reinigung von Cephalosporinen
CN105622636B (zh) * 2016-02-05 2017-08-25 河南理工大学 一种头孢妥仑匹酯中间体的制备方法
CN113480491B (zh) * 2021-09-08 2022-05-06 山东昌邑四方医药化工有限公司 一种从头孢托仑母核生产废液中回收4-甲基噻唑-5-甲醛和三苯基氧膦的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE58487B1 (en) * 1984-09-07 1993-09-22 Kaisha Maiji Seika New cephalosporin compounds and the production thereof
JPS6219593A (ja) 1985-07-18 1987-01-28 Meiji Seika Kaisha Ltd 新規セフエム化合物
JPH03128382A (ja) 1989-07-18 1991-05-31 Eisai Co Ltd チアゾリルアセトアミドセフェム系化合物
JPH06219593A (ja) * 1993-01-21 1994-08-09 Oki Electric Ind Co Ltd 電子写真記録装置
JP3128382B2 (ja) 1993-03-11 2001-01-29 旭 中野 鉄道車両運行支援表示装置
DE69427312T2 (de) 1993-11-17 2001-08-23 Biochemie Gmbh Trennung von Cephalosporinisomeren
JPH0867684A (ja) 1994-08-31 1996-03-12 Kyorin Pharmaceut Co Ltd 新規セフェム化合物、その製造法及び抗菌剤

Also Published As

Publication number Publication date
ES2182330T3 (es) 2003-03-01
CN1265662A (zh) 2000-09-06
ID24210A (id) 2000-07-13
UA55463C2 (uk) 2003-04-15
AU7933198A (en) 1999-01-04
CZ471899A3 (cs) 2000-07-12
CN1107679C (zh) 2003-05-07
RO120261B1 (ro) 2005-11-30
CA2294178A1 (en) 1998-12-30
SK283525B6 (sk) 2003-09-11
NZ502234A (en) 2001-06-29
US6288223B1 (en) 2001-09-11
SK185799A3 (en) 2000-07-11
PT1016665E (pt) 2002-12-31
KR100515273B1 (ko) 2005-09-15
KR20010014074A (ko) 2001-02-26
JP3713282B2 (ja) 2005-11-09
EA200000065A1 (ru) 2000-08-28
AU731265B2 (en) 2001-03-29
HUP0002458A3 (en) 2001-04-28
HU228767B1 (en) 2013-05-28
CA2294178C (en) 2003-07-22
EP1016665A1 (de) 2000-07-05
BR9810313B1 (pt) 2010-11-30
DE69807093T2 (de) 2003-03-27
PL193367B1 (pl) 2007-02-28
CZ295599B6 (cs) 2005-08-17
DE69807093D1 (de) 2002-09-12
HUP0002458A2 (hu) 2001-02-28
EP1016665A4 (de) 2001-06-13
IL133681A (en) 2003-10-31
IL133681A0 (en) 2001-04-30
EP1016665B1 (de) 2002-08-07
PL339361A1 (en) 2000-12-18
EA002449B1 (ru) 2002-04-25
WO1998058932A1 (fr) 1998-12-30
TR200000310T2 (tr) 2000-08-21
BR9810313A (pt) 2000-09-19

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