|
YU34199A
(sh)
*
|
1997-02-05 |
2002-08-12 |
F. Hoffmann-La Roche Ag. |
Primena inhibitora gastrointestinalne lipaze
|
|
WO2000009122A1
(en)
*
|
1998-08-14 |
2000-02-24 |
F. Hoffmann-La Roche Ag |
Pharmaceutical compositions containing lipase inhibitors
|
|
NZ510311A
(en)
*
|
1998-09-08 |
2003-08-29 |
Smithkline Beecham Corp |
Lipstatin derivative - soluble fiber tablets
|
|
AR025587A1
(es)
*
|
1999-09-13 |
2002-12-04 |
Hoffmann La Roche |
Formulaciones en dispersion que contienen inhibidores de lipasa
|
|
AR025609A1
(es)
*
|
1999-09-13 |
2002-12-04 |
Hoffmann La Roche |
Formulaciones lipidas solidas
|
|
EP1132389A1
(de)
|
2000-03-06 |
2001-09-12 |
Vernalis Research Limited |
Neue Azaindolyl-Derivate für die Behandlung von Fettleibigheit
|
|
DE10021618A1
(de)
*
|
2000-05-04 |
2001-11-15 |
Volker Helmstaedter |
Präparat für Darmerkrankungen und dessen Verwendung
|
|
YU96602A
(sh)
*
|
2000-06-27 |
2005-03-15 |
F.Hoffmann-La Roche Ag. |
Postupak za spravljanje smeše
|
|
PT1307264E
(pt)
|
2000-07-28 |
2005-02-28 |
Hoffmann La Roche |
Nova composicao farmaceutica
|
|
MXPA03000694A
(es)
*
|
2000-07-28 |
2003-06-04 |
Hoffmann La Roche |
Nuevo uso de los inhibidores de lipasa.
|
|
ATE390920T1
(de)
|
2000-08-09 |
2008-04-15 |
Hoffmann La Roche |
Lipase inhibitoren zur behandlung von dyspepsia
|
|
US6900226B2
(en)
*
|
2000-09-06 |
2005-05-31 |
Hoffman-La Roche Inc. |
Neuropeptide Y antagonists
|
|
ATE403647T1
(de)
|
2000-10-16 |
2008-08-15 |
Hoffmann La Roche |
Indolinderivate und deren verwendung als 5-ht2 rezeptor liganden
|
|
GB0030710D0
(en)
*
|
2000-12-15 |
2001-01-31 |
Hoffmann La Roche |
Piperazine derivatives
|
|
EP1347979B1
(de)
|
2000-12-27 |
2007-08-08 |
F. Hoffmann-La Roche Ag |
Indolderivate und deren verwendung als 5-ht2b- und 5-ht2c-rezeptorliganden
|
|
GB0106177D0
(en)
*
|
2001-03-13 |
2001-05-02 |
Hoffmann La Roche |
Piperazine derivatives
|
|
BR0209957A
(pt)
*
|
2001-05-21 |
2004-03-30 |
Hoffmann La Roche |
Composto, processo para a preparação de um composto, composição farmacêutica que compreende um composto, utilização desse composto e processo para o tratamento e profilaxia de artrite, diabetes, distúrbios alimentares e obesidade
|
|
US20030027786A1
(en)
|
2001-06-06 |
2003-02-06 |
Karsten Maeder |
Lipase inhibiting composition
|
|
US6787558B2
(en)
|
2001-09-28 |
2004-09-07 |
Hoffmann-La Roche Inc. |
Quinoline derivatives
|
|
US7357891B2
(en)
|
2001-10-12 |
2008-04-15 |
Monosol Rx, Llc |
Process for making an ingestible film
|
|
US20110033542A1
(en)
|
2009-08-07 |
2011-02-10 |
Monosol Rx, Llc |
Sublingual and buccal film compositions
|
|
US20190328679A1
(en)
|
2001-10-12 |
2019-10-31 |
Aquestive Therapeutics, Inc. |
Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
|
|
US20070281003A1
(en)
|
2001-10-12 |
2007-12-06 |
Fuisz Richard C |
Polymer-Based Films and Drug Delivery Systems Made Therefrom
|
|
US8900497B2
(en)
|
2001-10-12 |
2014-12-02 |
Monosol Rx, Llc |
Process for making a film having a substantially uniform distribution of components
|
|
US10285910B2
(en)
|
2001-10-12 |
2019-05-14 |
Aquestive Therapeutics, Inc. |
Sublingual and buccal film compositions
|
|
US8900498B2
(en)
|
2001-10-12 |
2014-12-02 |
Monosol Rx, Llc |
Process for manufacturing a resulting multi-layer pharmaceutical film
|
|
US11207805B2
(en)
|
2001-10-12 |
2021-12-28 |
Aquestive Therapeutics, Inc. |
Process for manufacturing a resulting pharmaceutical film
|
|
US8603514B2
(en)
|
2002-04-11 |
2013-12-10 |
Monosol Rx, Llc |
Uniform films for rapid dissolve dosage form incorporating taste-masking compositions
|
|
US8765167B2
(en)
|
2001-10-12 |
2014-07-01 |
Monosol Rx, Llc |
Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
|
|
DE10152351B4
(de)
*
|
2001-10-18 |
2005-09-22 |
Schering Ag |
Feste Arzneimittelformulierung für ein Piperazinharnstoffderivat
|
|
EP1448169A1
(de)
*
|
2001-11-07 |
2004-08-25 |
Fujisawa Pharmaceutical Co., Ltd. |
Methode zur verbesserung der löslichkeit von schwer-dispergierbaren medikamenten
|
|
US20050118258A1
(en)
*
|
2001-12-20 |
2005-06-02 |
Federico Shroppolo |
Pharmaceutical composition comprising skim milk powder
|
|
GB0202015D0
(en)
*
|
2002-01-29 |
2002-03-13 |
Hoffmann La Roche |
Piperazine Derivatives
|
|
JP4216196B2
(ja)
*
|
2002-02-04 |
2009-01-28 |
エフ.ホフマン−ラ ロシュ アーゲー |
Npyアンタゴニストとしてのキノリン誘導体
|
|
EP1480976B1
(de)
|
2002-02-28 |
2007-09-19 |
F.Hoffmann-La Roche Ag |
Thiazolderivate als npy-rezeptorantagonisten
|
|
WO2003090742A1
(en)
*
|
2002-04-26 |
2003-11-06 |
F. Hoffmann-La Roche Ag |
Pharmaceutical composition comprising a lipase inhibitor and glucomannan
|
|
KR100647932B1
(ko)
*
|
2002-07-05 |
2006-11-23 |
에프. 호프만-라 로슈 아게 |
퀴나졸린 유도체
|
|
RU2324685C2
(ru)
*
|
2002-08-07 |
2008-05-20 |
Ф.Хоффманн-Ля Рош Аг |
Производные тиазола, способ их получения и применение, фармацевтическая композиция, обладающая свойствами антагонистов рецепторов npy
|
|
ATE345340T1
(de)
*
|
2002-09-12 |
2006-12-15 |
Hoffmann La Roche |
N-substituierte-1h-indol-5-propansäure verbindungen als ppar-agonisten zur behandlung von diabetis
|
|
BR0316556A
(pt)
*
|
2002-11-25 |
2005-10-04 |
Hoffmann La Roche |
Compostos, processo para a preparação de um composto, composição farmacêutica que compreende esse composto, sua utilização e método para o tratamento e/ou profilaxia de enfermidades que são moduladas por agonistas ppar(alfa) e/ou ppary
|
|
US20040178058A1
(en)
*
|
2003-03-10 |
2004-09-16 |
Hsueh-Chung Chen |
Electro-chemical deposition apparatus and method of preventing cavities in an ECD copper film
|
|
GB0314967D0
(en)
*
|
2003-06-26 |
2003-07-30 |
Hoffmann La Roche |
Piperazine derivatives
|
|
BRPI0413500A
(pt)
*
|
2003-08-12 |
2006-10-10 |
Hoffmann La Roche |
compostos, processos para a sua preparação, composição farmacêutica que compreende os mesmos, utilização de um composto, métodos para o tratamento e profilaxia de artrite, diabetes, distúrbios alimentares e obesidade
|
|
EP1656374B1
(de)
*
|
2003-08-12 |
2009-03-11 |
F. Hoffmann-La Roche Ag |
Thiazolderivate als npy-antagonisten
|
|
US20060246141A1
(en)
*
|
2005-04-12 |
2006-11-02 |
Elan Pharma International, Limited |
Nanoparticulate lipase inhibitor formulations
|
|
WO2006117304A1
(en)
*
|
2005-05-03 |
2006-11-09 |
F. Hoffmann-La Roche Ag |
Tetracyclic azapyrazinoindolines as 5-ht2 ligands
|
|
KR100910000B1
(ko)
*
|
2005-05-13 |
2009-07-29 |
씨제이제일제당 (주) |
리파아제 저해제 함유 약학 조성물
|
|
WO2006132440A1
(ja)
*
|
2005-06-09 |
2006-12-14 |
Takeda Pharmaceutical Company Limited |
固形製剤
|
|
AU2006281435A1
(en)
*
|
2005-08-18 |
2007-02-22 |
F. Hoffmann-La Roche Ag |
Thiazolyl piperidine derivatives useful as H3 receptor modulators
|
|
US20070077310A1
(en)
*
|
2005-10-03 |
2007-04-05 |
University Of Tennessee Research Foundation |
Methods of reducing the production of reactive oxygen species and methods of screening or identifying compounds and compositions that reduce the production of reactive oxygen species
|
|
JP2009517434A
(ja)
*
|
2005-11-30 |
2009-04-30 |
エフ.ホフマン−ラ ロシュ アーゲー |
5−置換インドール−2−カルボキサミド誘導体
|
|
BRPI0619266A2
(pt)
*
|
2005-11-30 |
2011-09-27 |
Hoffmann La Roche |
compostos, processo para a sua manufatura, composições farmacêuticas, métodos para o tratamento e/ou prevenção de enfermidades que estão associadas com a modulação de receptores de h3, obesidade, diabetes do tipo ii e seu uso
|
|
CA2630314A1
(en)
*
|
2005-11-30 |
2007-06-07 |
F. Hoffmann-La Roche Ag |
1,5-substituted indol-2-yl amide derivatives
|
|
DE602006010433D1
(de)
*
|
2005-12-09 |
2009-12-24 |
Hoffmann La Roche |
Für die behandlung von obesitas geeignete tricyclische amidderivate
|
|
WO2007068620A1
(en)
*
|
2005-12-15 |
2007-06-21 |
F. Hoffmann-La Roche Ag |
Pyrrolo[2,3-c]pyridine derivatives
|
|
CA2631695A1
(en)
*
|
2005-12-16 |
2007-06-21 |
F. Hoffmann-La Roche Ag |
Pyrrolo[2,3-b]pyridine derivatives as h3 receptor modulators
|
|
EP1803714A1
(de)
*
|
2005-12-27 |
2007-07-04 |
KRKA, tovarna zdravil, d.d., Novo mesto |
Verfahren zur Herstellung kristalliner Formen von Orlistat
|
|
KR20080085031A
(ko)
*
|
2006-01-13 |
2008-09-22 |
에프. 호프만-라 로슈 아게 |
사이클로헥실 피페라지닐 메탄온 유도체 및 히스타민 h3수용체 조절제로서의 이의 용도
|
|
EP1979322B1
(de)
*
|
2006-01-23 |
2010-09-01 |
F. Hoffmann-La Roche AG |
Cyclohexyl-sulfonamid-derivate mit h3-rezeptoraktivität
|
|
US7432255B2
(en)
*
|
2006-05-16 |
2008-10-07 |
Hoffmann-La Roche Inc. |
1H-indol-5-yl-piperazin-1-yl-methanone derivatives
|
|
WO2007137955A1
(en)
*
|
2006-05-30 |
2007-12-06 |
F. Hoffmann-La Roche Ag |
Piperidinyl pyrimidine derivatives
|
|
EP1872777A1
(de)
*
|
2006-06-27 |
2008-01-02 |
LEK Pharmaceuticals D.D. |
Pharmazeutische Zusammensetzung enthaltend Tetrahydrolipstatin
|
|
US7514433B2
(en)
|
2006-08-03 |
2009-04-07 |
Hoffmann-La Roche Inc. |
1H-indole-6-yl-piperazin-1-yl-methanone derivatives
|
|
US20080146559A1
(en)
|
2006-12-08 |
2008-06-19 |
Li Chen |
4,5,6,7-Tetrahydro-Thieno [2,3-C] Pyridine Derivatives
|
|
TR200607613A2
(tr)
*
|
2006-12-29 |
2008-07-21 |
NOBEL İLAÇ SAN.ve TiC.A.Ş. |
Lipaz inhibitörü içeren farmasötik formülasyonlar
|
|
SI2002825T1
(sl)
*
|
2007-06-14 |
2013-10-30 |
Krka |
Farmacevtski sestavki, ki obsegajo orlistat
|
|
BRPI0817053A2
(pt)
*
|
2007-09-17 |
2015-03-24 |
Reddys Lab Ltd Dr |
Formulações farmacêuticas de orlistat
|
|
WO2009044380A2
(en)
|
2007-10-05 |
2009-04-09 |
Ranbaxy Laboratories Limited |
Formulations containing orlistat particles having controlled particle size
|
|
MX2010004072A
(es)
*
|
2007-10-15 |
2010-09-14 |
Inventis Dds Pvt Ltd |
Composicion farmaceutica de orlistat.
|
|
US8298583B2
(en)
|
2007-10-19 |
2012-10-30 |
Monosol Rx, Llc |
Film delivery system for tetrahydrolipstatin
|
|
US20090220593A1
(en)
*
|
2008-01-29 |
2009-09-03 |
Gulati Inder |
Extended release dosage forms of quetiapine
|
|
PL216542B1
(pl)
|
2008-03-20 |
2014-04-30 |
Zakłady Farmaceutyczne POLPHARMA Spółka Akcyjna |
Sposób wytwarzania stabilnej kompozycji orlistatu w postaci kapsułkowanego proszku
|
|
US8309107B2
(en)
*
|
2008-10-06 |
2012-11-13 |
Banner Pharmacaps, Inc. |
Stable solutions of orlistat for pharmaceutical dosage forms
|
|
BRPI0901602B8
(pt)
*
|
2009-04-03 |
2021-05-25 |
Ems S/A |
formulação farmacêuticas
|
|
MX342962B
(es)
|
2009-09-18 |
2016-06-07 |
Teva Pharmaceuticals Holdings Mexico S A De C V |
Composicion farmaceutica para bajar de peso y procedimiento para obtener la misma.
|
|
UA107369C2
(en)
|
2010-02-01 |
2014-12-25 |
Lab Bago S A |
Pharmaceutical composition with anti-obesity activity comprising a premixture of pure orlistat and preparation process
|
|
RU2441654C2
(ru)
*
|
2010-02-17 |
2012-02-10 |
Лабораториос Баго С.А. |
Фармацевтическая композиция с активностью против ожирения, включающая премикс чистого орлистата, и способ ее изготовления
|
|
US20120039999A1
(en)
|
2010-08-11 |
2012-02-16 |
Ashish Chatterji |
Pharmaceutical compositions of metabotropic glutamate 5 receptor (mglu5) antagonists
|
|
US20120040008A1
(en)
|
2010-08-11 |
2012-02-16 |
Ashish Chatterji |
Pharmaceutical compositions of metabotropic glutamate 5 receptor (mglu5) antagonists
|
|
US9149959B2
(en)
|
2010-10-22 |
2015-10-06 |
Monosol Rx, Llc |
Manufacturing of small film strips
|
|
KR101731155B1
(ko)
*
|
2011-06-15 |
2017-04-27 |
신톤 비.브이. |
안정화된 보리코나졸 조성물
|
|
RU2631597C2
(ru)
|
2011-07-15 |
2017-09-25 |
Нусерт Сайенсиз, Инк. |
Композиции и способы модулирования метаболических путей
|
|
CN102362863B
(zh)
*
|
2011-11-21 |
2013-06-12 |
山东新时代药业有限公司 |
一种含奥利司他的制剂及其制备方法
|
|
GB201122213D0
(en)
*
|
2011-12-23 |
2012-02-01 |
Norgine Bv |
Compositions
|
|
WO2013092786A1
(en)
|
2011-12-23 |
2013-06-27 |
Norgine B.V. |
Compositions comprising cetilistat
|
|
AU2012101841A4
(en)
*
|
2011-12-23 |
2013-01-17 |
Norgine Bv |
Compositions comprising cetilistat
|
|
US9198454B2
(en)
|
2012-03-08 |
2015-12-01 |
Nusirt Sciences, Inc. |
Compositions, methods, and kits for regulating energy metabolism
|
|
IN2014MN01933A
(de)
*
|
2012-03-13 |
2015-07-10 |
Piramal Entpr Ltd |
|
|
EP2919772B1
(de)
|
2012-11-13 |
2019-03-27 |
NuSirt Sciences, Inc. |
Pde5 inhibitoren und leucin oder ein leucin metabolit zur behandlung von diabetes
|
|
DE202012104963U1
(de)
|
2012-12-19 |
2013-01-14 |
Norgine B.V. |
Cetilistat aufweisende Zusammensetzungen
|
|
CA2902879C
(en)
|
2013-03-15 |
2023-09-26 |
Nusirt Sciences, Inc. |
Leucine and nicotinic acid reduces lipid levels
|
|
CN104740637A
(zh)
*
|
2013-12-31 |
2015-07-01 |
北京科信必成医药科技发展有限公司 |
一种稳定的奥利司他口服制剂及其制备方法
|
|
KR20160119863A
(ko)
|
2014-02-27 |
2016-10-14 |
뉴서트 사이언시스, 인크. |
간 지방증의 감소 또는 예방을 위한 조성물 및 방법
|
|
US10743813B2
(en)
|
2014-09-11 |
2020-08-18 |
Rattan Nath |
Diabetes control using postprandial feedback
|
|
US12433850B2
(en)
|
2016-05-05 |
2025-10-07 |
Aquestive Therapeutics, Inc. |
Enhanced delivery epinephrine and prodrug compositions
|
|
WO2017192921A1
(en)
|
2016-05-05 |
2017-11-09 |
Monosol Rx, Llc |
Enhanced delivery epinephrine compositions
|
|
US12427121B2
(en)
|
2016-05-05 |
2025-09-30 |
Aquestive Therapeutics, Inc. |
Enhanced delivery epinephrine compositions
|
|
US11273131B2
(en)
|
2016-05-05 |
2022-03-15 |
Aquestive Therapeutics, Inc. |
Pharmaceutical compositions with enhanced permeation
|
|
CN108785272B
(zh)
*
|
2018-09-04 |
2019-04-09 |
中山万汉制药有限公司 |
一种奥利司他软胶囊及其制备方法
|
|
CN115105476B
(zh)
*
|
2021-03-23 |
2023-11-14 |
山东新时代药业有限公司 |
一种奥利司他冻干口服制剂及其制备工艺
|
|
EP4422607A4
(de)
|
2021-10-25 |
2025-09-03 |
Aquestive Therapeutics Inc |
Orale und nasale zusammensetzungen und behandlungsverfahren
|
|
CN115300479A
(zh)
*
|
2022-08-23 |
2022-11-08 |
宁波高新区美诺华医药创新研究院有限公司 |
奥利司他胶囊制备方法
|