AT385036B - Verfahren zum herstellen von neuen carboxamidoderivaten von 5h-1,3,4-thiadiazolo(3,2-a)-pyrimidinen und ihren pharmazeutisch unbedenklichen salzen - Google Patents

Verfahren zum herstellen von neuen carboxamidoderivaten von 5h-1,3,4-thiadiazolo(3,2-a)-pyrimidinen und ihren pharmazeutisch unbedenklichen salzen

Info

Publication number
AT385036B
AT385036B AT0438383A AT438383A AT385036B AT 385036 B AT385036 B AT 385036B AT 0438383 A AT0438383 A AT 0438383A AT 438383 A AT438383 A AT 438383A AT 385036 B AT385036 B AT 385036B
Authority
AT
Austria
Prior art keywords
thiadiazolo
pyrimidines
producing new
pharmaceutically safe
safe salts
Prior art date
Application number
AT0438383A
Other languages
German (de)
English (en)
Other versions
ATA438383A (de
Inventor
Gianfederico Doria
Carlo Passarotti
Ada Buttinoni
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838329746A external-priority patent/GB8329746D0/en
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of ATA438383A publication Critical patent/ATA438383A/de
Application granted granted Critical
Publication of AT385036B publication Critical patent/AT385036B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
    • C07D285/125—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
    • C07D285/135—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT0438383A 1982-12-23 1983-12-15 Verfahren zum herstellen von neuen carboxamidoderivaten von 5h-1,3,4-thiadiazolo(3,2-a)-pyrimidinen und ihren pharmazeutisch unbedenklichen salzen AT385036B (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8236642 1982-12-23
GB838329746A GB8329746D0 (en) 1983-11-08 1983-11-08 Carboxamido-derivatives

Publications (2)

Publication Number Publication Date
ATA438383A ATA438383A (de) 1987-07-15
AT385036B true AT385036B (de) 1988-02-10

Family

ID=26284768

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0438383A AT385036B (de) 1982-12-23 1983-12-15 Verfahren zum herstellen von neuen carboxamidoderivaten von 5h-1,3,4-thiadiazolo(3,2-a)-pyrimidinen und ihren pharmazeutisch unbedenklichen salzen

Country Status (15)

Country Link
US (1) US4522944A (en:Method)
AT (1) AT385036B (en:Method)
AU (1) AU558600B2 (en:Method)
CA (1) CA1211440A (en:Method)
CH (1) CH657136A5 (en:Method)
DE (1) DE3346223A1 (en:Method)
DK (1) DK593983A (en:Method)
FI (1) FI834698A7 (en:Method)
FR (1) FR2538392B1 (en:Method)
GR (1) GR79479B (en:Method)
IL (1) IL70522A (en:Method)
IT (1) IT1194521B (en:Method)
NL (1) NL8304340A (en:Method)
SE (1) SE454698B (en:Method)
SU (1) SU1297731A3 (en:Method)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3702758A1 (de) * 1987-01-30 1988-09-29 Hoechst Ag Substituierte 3-phenyl-7h-thiazolo (3,2-b) (1,2,4) triazin-7-one, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung, sowie einige bei der herstellung der genannten verbindungen gebildete zwischenprodukte
EP3663294A1 (en) 2007-03-12 2020-06-10 Intra-Cellular Therapies, Inc. Substituted heterocycle fused gamma-carbolines synthesis
ES2727815T3 (es) 2012-04-14 2019-10-18 Intra Cellular Therapies Inc Tratamiento del TEPT y de trastornos del control de impulsos
PT2968320T (pt) 2013-03-15 2021-01-28 Intra Cellular Therapies Inc Compostos orgânicos
CN114366741A (zh) 2013-12-03 2022-04-19 细胞内治疗公司 新方法
KR20170012210A (ko) 2014-04-04 2017-02-02 인트라-셀룰라 써래피스, 인코퍼레이티드. 유기 화합물
MX2016013046A (es) 2014-04-04 2017-02-15 Intra Cellular Therapies Inc Compuestos organicos.
CN108883111B (zh) 2016-01-26 2021-10-08 细胞内治疗公司 有机化合物
US11014925B2 (en) 2016-03-28 2021-05-25 Intra-Cellular Therapies, Inc. Co-crystals of 1-(4-fluoro-phenyl)-4-((6bR,1OaS)-3-methyl-2,3,6b,9,10,10a-hexahydro-1H,7H- pyrido[3′,4′:4,51_pyrrolo [1,2,3-delqcuinoxalin-8-yl)-butan-1-one with nicotinamide or isonicotinamide
WO2017172795A1 (en) 2016-03-28 2017-10-05 Intra-Cellular Therapies, Inc. Novel compositions and methods
JP2019513143A (ja) 2016-03-28 2019-05-23 イントラ−セルラー・セラピーズ・インコーポレイテッドＩｎｔｒａ−Ｃｅｌｌｕｌａｒ Ｔｈｅｒａｐｉｅｓ， Ｉｎｃ． 新規塩類および結晶
EP3525763B1 (en) 2016-10-12 2025-03-05 Intra-Cellular Therapies, Inc. Amorphous solid dispersions
WO2018126140A1 (en) 2016-12-29 2018-07-05 Intra-Cellular Therapies, Inc. Organic compounds
US10906906B2 (en) 2016-12-29 2021-02-02 Intra-Cellular Therapies, Inc. Organic compounds
MX387784B (es) 2017-03-24 2025-03-18 Intra Celular Therapies Inc Composiciones novedosas y metodos.
CN111093664B (zh) 2017-07-26 2023-06-02 细胞内治疗公司 有机化合物
BR112020001666A2 (pt) 2017-07-26 2020-07-21 Intra-Cellular Therapies, Inc. compostos orgânicos
JP7462568B2 (ja) 2018-03-23 2024-04-05 イントラ－セルラー・セラピーズ・インコーポレイテッド 有機化合物
JP7476115B2 (ja) 2018-06-06 2024-04-30 イントラ－セルラー・セラピーズ・インコーポレイテッド 新規の塩および結晶
MX2020013335A (es) 2018-06-08 2021-05-27 Intra Cellular Therapies Inc Metodos novedosos.
CN110831941A (zh) 2018-06-11 2020-02-21 细胞内治疗公司 取代的杂环稠合的γ-咔啉类化合物合成
WO2020047241A1 (en) 2018-08-29 2020-03-05 Intra-Cellular Therapies, Inc. Novel compositions and methods
EP3843739A4 (en) 2018-08-31 2022-06-01 Intra-Cellular Therapies, Inc. Novel methods
BR112021003655A2 (pt) 2018-08-31 2021-05-18 Intra-Cellular Therapies, Inc. métodos novos
EP3993798A4 (en) 2019-07-07 2023-04-26 Intra-Cellular Therapies, Inc. NOVEL PROCESSES
WO2021119334A1 (en) 2019-12-11 2021-06-17 Intra-Cellular Therapies, Inc. Organic compound
US12414948B2 (en) 2022-05-18 2025-09-16 Intra-Cellular Therapies, Inc. Methods

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5129981B2 (en:Method) * 1973-07-17 1976-08-28
GB1568962A (en) * 1975-10-31 1980-06-11 Beecham Group Ltd Reparation and compositions containing them (heterocyclic-carbonylamino)pencillins methods for their p
JPS55115889A (en) * 1979-02-28 1980-09-06 Teijin Ltd 6-carbamoylthiazolo 3,2-a pyrimidine derivative and its preparation
JPS57142989A (en) * 1981-02-27 1982-09-03 Dai Ichi Seiyaku Co Ltd Thiazolopyrimidine derivative

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACT 76(1972) 59562 G *
CHEMICAL ABSTRACT 84(1976) 4010 K *

Also Published As

Publication number Publication date
AU2252583A (en) 1984-06-28
DK593983D0 (da) 1983-12-22
US4522944A (en) 1985-06-11
SE8307133L (sv) 1984-06-24
NL8304340A (nl) 1984-07-16
GR79479B (en:Method) 1984-10-30
DE3346223A1 (de) 1984-06-28
CH657136A5 (de) 1986-08-15
CA1211440A (en) 1986-09-16
DK593983A (da) 1984-06-24
SU1297731A3 (ru) 1987-03-15
FI834698A0 (fi) 1983-12-20
ATA438383A (de) 1987-07-15
FR2538392B1 (fr) 1987-01-16
IL70522A0 (en) 1984-03-30
FI834698A7 (fi) 1984-06-24
IL70522A (en) 1986-02-28
SE454698B (sv) 1988-05-24
IT8324207A0 (it) 1983-12-16
IT1194521B (it) 1988-09-22
AU558600B2 (en) 1987-02-05
FR2538392A1 (fr) 1984-06-29
SE8307133D0 (sv) 1983-12-22

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