MX2020013335A - Metodos novedosos. - Google Patents
Metodos novedosos.Info
- Publication number
- MX2020013335A MX2020013335A MX2020013335A MX2020013335A MX2020013335A MX 2020013335 A MX2020013335 A MX 2020013335A MX 2020013335 A MX2020013335 A MX 2020013335A MX 2020013335 A MX2020013335 A MX 2020013335A MX 2020013335 A MX2020013335 A MX 2020013335A
- Authority
- MX
- Mexico
- Prior art keywords
- sub
- novel methods
- opioid receptor
- mtorc1
- neuroinflammation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/16—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La divulgación proporciona métodos para el tratamiento agudo de depresión y/o ansiedad, para mejorar la señalización de mTOR (por ejemplo, mTORC1) y para la reducción de la neuroinflamación; que comprende administrar a un paciente que lo necesite, una cantidad terapéuticamente eficaz de un ligando del receptor 5-HT2A/opioide mu o del receptor 5-HT2A/D1 y/o D2/opioide mu.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862682554P | 2018-06-08 | 2018-06-08 | |
US201862780017P | 2018-12-14 | 2018-12-14 | |
PCT/US2019/036114 WO2019237037A1 (en) | 2018-06-08 | 2019-06-07 | Novel methods |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2020013335A true MX2020013335A (es) | 2021-05-27 |
Family
ID=68769463
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2020013335A MX2020013335A (es) | 2018-06-08 | 2019-06-07 | Metodos novedosos. |
Country Status (5)
Country | Link |
---|---|
US (1) | US20210093634A1 (es) |
EP (1) | EP3801527A4 (es) |
CA (1) | CA3102948A1 (es) |
MX (1) | MX2020013335A (es) |
WO (1) | WO2019237037A1 (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX2018009158A (es) | 2016-01-26 | 2018-11-19 | Intra Cellular Therapies Inc | Compuestos organicos. |
CN111093665A (zh) * | 2017-07-26 | 2020-05-01 | 细胞内治疗公司 | 有机化合物 |
EP3898581A4 (en) * | 2018-12-17 | 2022-08-17 | Intra-Cellular Therapies, Inc. | SYNTHESIS OF CONDENSED GAMMA-CARBOLINES WITH SUBSTITUTED HETEROCYCLE |
KR20210104833A (ko) * | 2018-12-17 | 2021-08-25 | 인트라-셀룰라 써래피스, 인코퍼레이티드. | 치환된 헤테로사이클 융합 감마-카르볼린 합성 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105237536A (zh) * | 2008-03-12 | 2016-01-13 | 细胞内治疗公司 | 取代的杂环稠合的γ-咔啉固体 |
ES2602503T3 (es) * | 2010-04-22 | 2017-02-21 | Intra-Cellular Therapies, Inc. | Compuestos orgánicos |
IN2014DN08562A (es) * | 2012-04-14 | 2015-05-22 | Intra Cellular Therapies Inc | |
MX2018009158A (es) * | 2016-01-26 | 2018-11-19 | Intra Cellular Therapies Inc | Compuestos organicos. |
-
2019
- 2019-06-07 CA CA3102948A patent/CA3102948A1/en active Pending
- 2019-06-07 EP EP19815161.5A patent/EP3801527A4/en active Pending
- 2019-06-07 MX MX2020013335A patent/MX2020013335A/es unknown
- 2019-06-07 WO PCT/US2019/036114 patent/WO2019237037A1/en unknown
-
2020
- 2020-12-08 US US17/115,416 patent/US20210093634A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
CA3102948A1 (en) | 2019-12-12 |
EP3801527A4 (en) | 2022-03-30 |
US20210093634A1 (en) | 2021-04-01 |
EP3801527A1 (en) | 2021-04-14 |
WO2019237037A1 (en) | 2019-12-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX2020009668A (es) | Métodos novedosos. | |
MX2020013335A (es) | Metodos novedosos. | |
EA201000603A1 (ru) | ПРИМЕНЕНИЕ АНТИТЕЛ К TrkB ДЛЯ ЛЕЧЕНИЯ РЕСПИРАТОРНЫХ НАРУШЕНИЙ | |
NZ611108A (en) | Methods of treating fgf21-associated disorders | |
MX2022013172A (es) | Uso de un inhibidor de pcsk9 para tratar la hiperlipidemia. | |
PH12020551425A1 (en) | Rimegepant for cgrp related disorders | |
UA109878C2 (uk) | Похідні ізохінолінону, фармацевтична композиція на їх основі (варіанти) та спосіб лікування захворювань (варіанти) | |
EA200700262A1 (ru) | Арилидены для лечения заболеваний, опосредуемых эстроген-родственным рецепторам альфа | |
NZ737399A (en) | Ccr2 modulators | |
TNSN07028A1 (en) | Fused ring heterocycle kinase modulators | |
MX2009013194A (es) | Proteinas de fusion del receptor para productos finales de glicacion avanzada. | |
EA202090510A1 (ru) | Способ лечения бокового амиотрофического склероза придопидином | |
MY179105A (en) | Methods of treating alzheimer's disease | |
WO2021203103A3 (en) | Ace2 receptor polymorphisms and varying susceptibility to sars-cov-2, methods for diagnosis and treatment | |
EA201792575A1 (ru) | Фармацевтические композиции леветирацетама пролонгированного высвобождения | |
MX2021002322A (es) | Nuevos metodos. | |
MA53711A (fr) | Antagonistes de récepteur alpha 2-adrénergiques de sous-type c (alpha-2c) pour le traitement de l'apnée du sommeil | |
MX2021010665A (es) | Metodos de tratamiento de amiloidosis al. | |
EA201691656A2 (ru) | Терапевтические способы с применением норибогаина и родственных соединений | |
MX2020009532A (es) | Oligonucleotidos modificados para uso en el tratamiento de tauopatias. | |
MX2019014090A (es) | Métodos para el tratamiento de la reservoritis crónica. | |
MA44660B1 (fr) | (+) -azasetron pour son utilisation dans le traitement des troubles de l'oreille | |
WO2015036643A3 (es) | Marcador para predecir metástasis del cáncer de mama | |
PH12021550671A1 (en) | Prodrugs of cgrp antagonists | |
WO2018229551A3 (en) | METHODS OF TREATING A DISORDER RELATED TO THE USE OF OPIOIDS |