FI895826A0 - Stereospesifinen menetelmä furo/3,4-c/pyridiini-enantiomeerien valmistamiseksi - Google Patents

Stereospesifinen menetelmä furo/3,4-c/pyridiini-enantiomeerien valmistamiseksi

Info

Publication number
FI895826A0
FI895826A0 FI895826A FI895826A FI895826A0 FI 895826 A0 FI895826 A0 FI 895826A0 FI 895826 A FI895826 A FI 895826A FI 895826 A FI895826 A FI 895826A FI 895826 A0 FI895826 A0 FI 895826A0
Authority
FI
Finland
Prior art keywords
furo
preparation
stereospecific method
enantiomers
pyridine
Prior art date
Application number
FI895826A
Other languages
English (en)
Swedish (sv)
Other versions
FI93116C (fi
FI93116B (fi
Inventor
Marc Bonato
Charles Eck
Original Assignee
Scras
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scras filed Critical Scras
Publication of FI895826A0 publication Critical patent/FI895826A0/fi
Application granted granted Critical
Publication of FI93116B publication Critical patent/FI93116B/fi
Publication of FI93116C publication Critical patent/FI93116C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
FI895826A 1988-04-06 1989-12-05 Stereospesifinen menetelmä furo/3,4-c/pyridiini-enantiomeerien valmistamiseksi FI93116C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB888808001A GB8808001D0 (en) 1988-04-06 1988-04-06 Stereospecific preparative process for furol(3,4-c)pyridine derivatives
GB8808001 1988-04-06
PCT/FR1989/000157 WO1989009772A1 (fr) 1988-04-06 1989-04-06 PROCEDE STEREOSPECIFIQUE POUR LA PREPARATION DES ENANTIOMERES DE LA FURO[3,4-c]PYRIDINE, COMPOSES AINSI OBTENUS ET COMPOSITIONS THERAPEUTIQUES A BASE DE CES COMPOSES
FR8900157 1989-04-06

Publications (3)

Publication Number Publication Date
FI895826A0 true FI895826A0 (fi) 1989-12-05
FI93116B FI93116B (fi) 1994-11-15
FI93116C FI93116C (fi) 1995-02-27

Family

ID=10634633

Family Applications (1)

Application Number Title Priority Date Filing Date
FI895826A FI93116C (fi) 1988-04-06 1989-12-05 Stereospesifinen menetelmä furo/3,4-c/pyridiini-enantiomeerien valmistamiseksi

Country Status (28)

Country Link
US (1) US5026855A (fi)
EP (1) EP0337858B1 (fi)
JP (1) JP2680456B2 (fi)
KR (1) KR970005308B1 (fi)
AT (1) AT397093B (fi)
AU (1) AU616753B2 (fi)
BE (1) BE1003843A4 (fi)
CA (1) CA1338475C (fi)
CH (1) CH680000A5 (fi)
DK (1) DK167020B1 (fi)
DZ (1) DZ1335A1 (fi)
ES (1) ES2057159T3 (fi)
FI (1) FI93116C (fi)
FR (2) FR2629820B1 (fi)
GB (2) GB8808001D0 (fi)
IE (1) IE61915B1 (fi)
IN (1) IN172987B (fi)
MA (1) MA21529A1 (fi)
MY (1) MY104424A (fi)
NL (1) NL8920307A (fi)
NZ (1) NZ228614A (fi)
OA (1) OA09247A (fi)
PT (1) PT90210B (fi)
SE (1) SE509130C2 (fi)
SG (1) SG40492G (fi)
TN (1) TNSN89043A1 (fi)
WO (1) WO1989009772A1 (fi)
ZA (1) ZA892477B (fi)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8808001D0 (en) * 1988-04-06 1988-05-05 Scras Stereospecific preparative process for furol(3,4-c)pyridine derivatives
GB8907480D0 (en) * 1989-04-03 1989-05-17 Scaras Societe De Conseils De Separation of insomers of furo(3,4-c)pyridine derivatives
GB8917168D0 (en) * 1989-07-27 1989-09-13 Scras Asymmetric synthesis of furo(3,4-c)pyridine derivatives
US5130252A (en) * 1990-05-14 1992-07-14 Synthetech, Inc. Resolution of furopyridine enantiomers and synthetic precursors thereof
US20060089374A1 (en) * 2003-07-17 2006-04-27 Glenn Cornett Enantiomeric compositions of cicletanine, alone and in combination with other agents, for the treatment of disease
CA2537180A1 (en) * 2003-08-29 2005-03-10 Cotherix, Inc. Cicletanine in combination with oral antidiabetic and/or blood lipid-lowering agents as a combination therapy for diabetes and metabolic syndrome
US20060154959A1 (en) * 2005-01-13 2006-07-13 Navitas Pharma Combination therapies of cicletanine and carvedilol
US20070141174A1 (en) * 2005-01-13 2007-06-21 Navitas Pharma, Inc. Enantiomeric compositions of cicletanine, in combination with other agents, for the treatment of hypertension
US20080096915A1 (en) * 2005-01-13 2008-04-24 Greenberg Traurig LLP Compositions for the treatment of metabolic disorders
US20070105817A1 (en) * 2005-11-09 2007-05-10 Jim Page Use of cicletanine and other furopyridines for treatment of systolic-predominant hypertension, isolated systolic hypertension, elevated pulse pressure, and general hypertension
CA2674367A1 (en) * 2007-01-03 2008-07-17 Glenn V. Cornett Cicletanine and pkc inhibitors in the treatment of pulmonary and cardiac disorders
AR073259A1 (es) * 2008-07-29 2010-10-28 Merck & Co Inc Derivados de furosemida utiles como diureticos
WO2011043914A1 (en) * 2009-10-09 2011-04-14 Merck Sharp & Dohme Corp. Diuretics
US9522138B2 (en) * 2013-12-31 2016-12-20 Don C. Rockey Systems, methods, techniques, and compounds in research and treatment of portal hypertension and other conditions

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4244951A (en) * 1979-05-16 1981-01-13 Pfizer Inc. Bis-esters of methanediol with penicillins and penicillanic acid 1,1-dioxide
IN156817B (fi) * 1981-02-10 1985-11-09 Scras
US4735950A (en) * 1983-04-05 1988-04-05 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S) Furo-(3,4-C)-pyridine derivatives and therapeutic composition containing the same
GB2137618B (en) * 1983-04-05 1986-05-08 Scras Furo-(3,4-c)-pyridine derivatives
IN160104B (fi) * 1983-04-05 1987-06-27 Scras
ZA842029B (en) * 1983-04-05 1984-10-31 Scras Furo-(3,4-c)-pyridine derivatives preparation thereof and therapeutic compositions containing the same
GB8327817D0 (en) * 1983-10-18 1983-11-16 Scras 4-halo-furo-(3 4-c)-pyridine derivatives
GB8330517D0 (en) * 1983-11-16 1983-12-21 Scras 6-vinyl-furo-(3,4-c)pyridine derivatives
GB8330658D0 (en) * 1983-11-17 1983-12-29 Scras 7-carboxymethoxy-furo-(3,4-c)-pyridine derivatives
GB8402740D0 (en) * 1984-02-02 1984-03-07 Scras Furo-(3 4-c)-pyridine derivatives
GB8414559D0 (en) * 1984-06-07 1984-07-11 Scras Pyridine derivatives
GB8422029D0 (en) * 1984-08-31 1984-10-03 Scras 6-substituted-furo-(3 4-c)-pyridine derivatives
GB8422379D0 (en) * 1984-09-05 1984-10-10 Scras Derivatives
GB8427218D0 (en) * 1984-10-27 1984-12-05 Scras Pyridine derivatives
DE3519693A1 (de) * 1985-06-01 1987-01-02 Basf Ag Pyridin-derivate, ihre herstellung und verwendung
GB8808001D0 (en) * 1988-04-06 1988-05-05 Scras Stereospecific preparative process for furol(3,4-c)pyridine derivatives
GB8907480D0 (en) * 1989-04-03 1989-05-17 Scaras Societe De Conseils De Separation of insomers of furo(3,4-c)pyridine derivatives

Also Published As

Publication number Publication date
US5026855A (en) 1991-06-25
JP2680456B2 (ja) 1997-11-19
AU3419089A (en) 1989-11-03
KR900700483A (ko) 1990-08-13
CA1338475C (en) 1996-07-23
MY104424A (en) 1994-03-31
SG40492G (en) 1992-06-12
ATA900589A (de) 1993-06-15
IE891076L (en) 1989-10-06
DK611689A (da) 1989-12-05
BE1003843A4 (fr) 1992-06-30
ES2057159T3 (es) 1994-10-16
EP0337858A1 (fr) 1989-10-18
NL8920307A (nl) 1990-03-01
IE61915B1 (en) 1994-11-30
FR2629820B1 (fr) 1993-12-03
IN172987B (fi) 1994-01-15
EP0337858B1 (fr) 1994-06-08
KR970005308B1 (ko) 1997-04-15
DK167020B1 (da) 1993-08-16
TNSN89043A1 (fr) 1991-02-04
JPH02504394A (ja) 1990-12-13
CH680000A5 (fi) 1992-05-29
FR2629821B1 (fr) 1993-12-03
GB8808001D0 (en) 1988-05-05
FR2629821A1 (fr) 1989-10-13
AT397093B (de) 1994-01-25
SE8904104D0 (sv) 1989-12-05
FI93116C (fi) 1995-02-27
DK611689D0 (da) 1989-12-05
GB8927509D0 (en) 1990-06-13
SE509130C2 (sv) 1998-12-07
MA21529A1 (fr) 1989-12-31
GB2235194B (en) 1992-01-29
PT90210A (pt) 1989-11-10
FR2629820A1 (fr) 1989-10-13
NZ228614A (en) 1990-11-27
ZA892477B (en) 1989-12-27
SE8904104L (sv) 1989-12-05
AU616753B2 (en) 1991-11-07
WO1989009772A1 (fr) 1989-10-19
OA09247A (fr) 1992-06-30
GB2235194A (en) 1991-02-27
FI93116B (fi) 1994-11-15
PT90210B (pt) 1994-06-30
DZ1335A1 (fr) 2004-09-13

Similar Documents

Publication Publication Date Title
CS8701093A2 (en) Method of new cycloalkano/1,2-b/-indolesulphoamides production
AU5845786A (en) Pyrano(3,2-C) pyridine derivatives
NO850399L (no) Fremgangsmaate for fremstilling av 6-substituerte furo (3,4-c)pyridin-derivater
NO841322L (no) Fremgangsmaate for fremstilling av furo (3,4-c)-pyridin-derivater
FI895826A0 (fi) Stereospesifinen menetelmä furo/3,4-c/pyridiini-enantiomeerien valmistamiseksi
PL266231A1 (en) The method of manufacture of new derivatives of dilnidropyridine
GB2176772B (en) Process for producing clay derivatives and clay derivatives obtained by the process
NO180308C (no) Fremgangsmåte for fremstilling av en tilnærmet ikke-racemisk form av furo (3,4-c) pyridin-derivater
CS567989A2 (en) Method of substituted 1,3,5-triazintriones production
IL88163A (en) Method for the preparation of anilopiperidine derivatives
EP0245835A3 (en) Novel thiophene derivatives and methods for producing the same
ATA310385A (de) Verfahren zur herstellung neuer 6-phenaethylaminoalkyl-7-hydroxy-furo-(3,4-c)pyridinderivate
CS960486A2 (en) Method of pregnale-21-acid's 16,17-acetal-substituted derivatives production
MA20543A1 (fr) Derives de thierro et furo-[2,3-c]pyroles procedes de preparation les contenant
AU2330488A (en) Improved method for the preparation of anilinofumarate
EP0359118A3 (en) Method for the production of 1,1,2-trialkoxyethanes
TR23831A (tr) Karbon karasi ueretme metodu
NL194915B (nl) Scheiding van enantiomeren van 7-hydroxy-furo[3,4-c]pyridinederivaten.
KR860005820A (ko) 2-아미노-5-옥소-5H-[1]벤조피라노[2,3-b]피리딘-3-카르복실산 유도체의 제조방법
GB2234244B (en) Asymmetric synthesis of furo[3,4-c]pyridine derivatives
HK47392A (en) Stereospecific process for the preparation of furo(3,4-c)pyridine enantiomers,compounds thus obtained and therapeutical compositions thereof
PL263015A1 (en) The method of manufacture of derivatives of 6-h-indol/2,3-b/-quinoline
PL271544A1 (en) Method of obtaining novel derivatives of thieneimidazo-2,1-b-thiazole
PL265216A1 (en) Method of obtaining 1,4:3,6-dianhydro-d-sorbite 2,5-dinitrate
HUT45251A (en) Process for producing 2-fenyl-imidazo/4,5-c/ derivatives substituted with alkyl-sulfinyl-group

Legal Events

Date Code Title Description
BB Publication of examined application
FG Patent granted

Owner name: SOCIETE DE CONSEILS DE RECHERCHES ET D APPLICATION

MA Patent expired