ZA892477B - Stereospecific process for the preparation of furo(3,4-c)pyridine enantiomers and compounds thus obtained - Google Patents

Stereospecific process for the preparation of furo(3,4-c)pyridine enantiomers and compounds thus obtained

Info

Publication number
ZA892477B
ZA892477B ZA892477A ZA892477A ZA892477B ZA 892477 B ZA892477 B ZA 892477B ZA 892477 A ZA892477 A ZA 892477A ZA 892477 A ZA892477 A ZA 892477A ZA 892477 B ZA892477 B ZA 892477B
Authority
ZA
South Africa
Prior art keywords
furo
compounds
preparation
stereospecific process
enantiomers
Prior art date
Application number
ZA892477A
Other languages
English (en)
Inventor
Marc Bonato
Bonato Marc
Charles R Eck
R Eck Charles
Original Assignee
Scras
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scras filed Critical Scras
Publication of ZA892477B publication Critical patent/ZA892477B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
ZA892477A 1988-04-06 1989-04-04 Stereospecific process for the preparation of furo(3,4-c)pyridine enantiomers and compounds thus obtained ZA892477B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888808001A GB8808001D0 (en) 1988-04-06 1988-04-06 Stereospecific preparative process for furol(3,4-c)pyridine derivatives

Publications (1)

Publication Number Publication Date
ZA892477B true ZA892477B (en) 1989-12-27

Family

ID=10634633

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA892477A ZA892477B (en) 1988-04-06 1989-04-04 Stereospecific process for the preparation of furo(3,4-c)pyridine enantiomers and compounds thus obtained

Country Status (28)

Country Link
US (1) US5026855A (xx)
EP (1) EP0337858B1 (xx)
JP (1) JP2680456B2 (xx)
KR (1) KR970005308B1 (xx)
AT (1) AT397093B (xx)
AU (1) AU616753B2 (xx)
BE (1) BE1003843A4 (xx)
CA (1) CA1338475C (xx)
CH (1) CH680000A5 (xx)
DK (1) DK167020B1 (xx)
DZ (1) DZ1335A1 (xx)
ES (1) ES2057159T3 (xx)
FI (1) FI93116C (xx)
FR (2) FR2629821B1 (xx)
GB (2) GB8808001D0 (xx)
IE (1) IE61915B1 (xx)
IN (1) IN172987B (xx)
MA (1) MA21529A1 (xx)
MY (1) MY104424A (xx)
NL (1) NL8920307A (xx)
NZ (1) NZ228614A (xx)
OA (1) OA09247A (xx)
PT (1) PT90210B (xx)
SE (1) SE509130C2 (xx)
SG (1) SG40492G (xx)
TN (1) TNSN89043A1 (xx)
WO (1) WO1989009772A1 (xx)
ZA (1) ZA892477B (xx)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8808001D0 (en) * 1988-04-06 1988-05-05 Scras Stereospecific preparative process for furol(3,4-c)pyridine derivatives
GB8907480D0 (en) * 1989-04-03 1989-05-17 Scaras Societe De Conseils De Separation of insomers of furo(3,4-c)pyridine derivatives
GB8917168D0 (en) * 1989-07-27 1989-09-13 Scras Asymmetric synthesis of furo(3,4-c)pyridine derivatives
US5130252A (en) * 1990-05-14 1992-07-14 Synthetech, Inc. Resolution of furopyridine enantiomers and synthetic precursors thereof
US20060089374A1 (en) * 2003-07-17 2006-04-27 Glenn Cornett Enantiomeric compositions of cicletanine, alone and in combination with other agents, for the treatment of disease
GB2423927A (en) * 2003-08-29 2006-09-13 Cotherix Inc Combination Of Cicletanine And An Oral Antidiabetic And/Or Blood Lipid-Lowering Agent For Treating Diabetes And Metabolic Syndrome
US20060154959A1 (en) * 2005-01-13 2006-07-13 Navitas Pharma Combination therapies of cicletanine and carvedilol
US20080096915A1 (en) * 2005-01-13 2008-04-24 Greenberg Traurig LLP Compositions for the treatment of metabolic disorders
US20070141174A1 (en) * 2005-01-13 2007-06-21 Navitas Pharma, Inc. Enantiomeric compositions of cicletanine, in combination with other agents, for the treatment of hypertension
US20070105817A1 (en) * 2005-11-09 2007-05-10 Jim Page Use of cicletanine and other furopyridines for treatment of systolic-predominant hypertension, isolated systolic hypertension, elevated pulse pressure, and general hypertension
CA2674367A1 (en) * 2007-01-03 2008-07-17 Glenn V. Cornett Cicletanine and pkc inhibitors in the treatment of pulmonary and cardiac disorders
AR073259A1 (es) * 2008-07-29 2010-10-28 Merck & Co Inc Derivados de furosemida utiles como diureticos
EP2485734B1 (en) * 2009-10-09 2014-07-02 Merck Sharp & Dohme Corp. Diuretics
WO2015103445A1 (en) * 2013-12-31 2015-07-09 Rockey Don C Systems, methods, techniques, and compounds in research and treatment of portal hypertension and other conditions

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4244951A (en) * 1979-05-16 1981-01-13 Pfizer Inc. Bis-esters of methanediol with penicillins and penicillanic acid 1,1-dioxide
IN156817B (xx) * 1981-02-10 1985-11-09 Scras
US4735950A (en) * 1983-04-05 1988-04-05 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S) Furo-(3,4-C)-pyridine derivatives and therapeutic composition containing the same
IN160104B (xx) * 1983-04-05 1987-06-27 Scras
ZA842029B (en) * 1983-04-05 1984-10-31 Scras Furo-(3,4-c)-pyridine derivatives preparation thereof and therapeutic compositions containing the same
GB2137618B (en) * 1983-04-05 1986-05-08 Scras Furo-(3,4-c)-pyridine derivatives
GB8327817D0 (en) * 1983-10-18 1983-11-16 Scras 4-halo-furo-(3 4-c)-pyridine derivatives
GB8330517D0 (en) * 1983-11-16 1983-12-21 Scras 6-vinyl-furo-(3,4-c)pyridine derivatives
GB8330658D0 (en) * 1983-11-17 1983-12-29 Scras 7-carboxymethoxy-furo-(3,4-c)-pyridine derivatives
GB8402740D0 (en) * 1984-02-02 1984-03-07 Scras Furo-(3 4-c)-pyridine derivatives
GB8414559D0 (en) * 1984-06-07 1984-07-11 Scras Pyridine derivatives
GB8422029D0 (en) * 1984-08-31 1984-10-03 Scras 6-substituted-furo-(3 4-c)-pyridine derivatives
GB8422379D0 (en) * 1984-09-05 1984-10-10 Scras Derivatives
GB8427218D0 (en) * 1984-10-27 1984-12-05 Scras Pyridine derivatives
DE3519693A1 (de) * 1985-06-01 1987-01-02 Basf Ag Pyridin-derivate, ihre herstellung und verwendung
GB8808001D0 (en) * 1988-04-06 1988-05-05 Scras Stereospecific preparative process for furol(3,4-c)pyridine derivatives
GB8907480D0 (en) * 1989-04-03 1989-05-17 Scaras Societe De Conseils De Separation of insomers of furo(3,4-c)pyridine derivatives

Also Published As

Publication number Publication date
SE8904104L (sv) 1989-12-05
OA09247A (fr) 1992-06-30
FI93116C (fi) 1995-02-27
JP2680456B2 (ja) 1997-11-19
US5026855A (en) 1991-06-25
AT397093B (de) 1994-01-25
DZ1335A1 (fr) 2004-09-13
SE8904104D0 (sv) 1989-12-05
FR2629820A1 (fr) 1989-10-13
IE61915B1 (en) 1994-11-30
PT90210A (pt) 1989-11-10
GB2235194A (en) 1991-02-27
SE509130C2 (sv) 1998-12-07
JPH02504394A (ja) 1990-12-13
CA1338475C (en) 1996-07-23
SG40492G (en) 1992-06-12
MY104424A (en) 1994-03-31
DK611689D0 (da) 1989-12-05
GB8808001D0 (en) 1988-05-05
FR2629820B1 (fr) 1993-12-03
BE1003843A4 (fr) 1992-06-30
PT90210B (pt) 1994-06-30
KR970005308B1 (ko) 1997-04-15
AU616753B2 (en) 1991-11-07
CH680000A5 (xx) 1992-05-29
IN172987B (xx) 1994-01-15
AU3419089A (en) 1989-11-03
EP0337858A1 (fr) 1989-10-18
KR900700483A (ko) 1990-08-13
GB2235194B (en) 1992-01-29
FI93116B (fi) 1994-11-15
IE891076L (en) 1989-10-06
DK167020B1 (da) 1993-08-16
MA21529A1 (fr) 1989-12-31
FR2629821B1 (fr) 1993-12-03
EP0337858B1 (fr) 1994-06-08
WO1989009772A1 (fr) 1989-10-19
DK611689A (da) 1989-12-05
ES2057159T3 (es) 1994-10-16
FR2629821A1 (fr) 1989-10-13
FI895826A0 (fi) 1989-12-05
ATA900589A (de) 1993-06-15
GB8927509D0 (en) 1990-06-13
NZ228614A (en) 1990-11-27
NL8920307A (nl) 1990-03-01
TNSN89043A1 (fr) 1991-02-04

Similar Documents

Publication Publication Date Title
CS8701093A2 (en) Method of new cycloalkano/1,2-b/-indolesulphoamides production
ZA893436B (en) Process for the preparation of dideoxycytidine
KR950010075B1 (en) Process for the preparation of 1,2,3,6-tetrahydro-5-nitro-pyrimidine derivatives
ZA892477B (en) Stereospecific process for the preparation of furo(3,4-c)pyridine enantiomers and compounds thus obtained
EP0237735A3 (en) 3,7-disubstituted-3-cephem compounds and process for production of the same
EP0235647A3 (en) Process for the manufacture of 6,13-dihydroquinacridones and quinacridones
IL82858A0 (en) Process for the preparation of 1,2,5,6,9,10-hexabromo-cyclododecane
CS567989A2 (en) Method of substituted 1,3,5-triazintriones production
EP0297496A3 (en) Novel process for the preparation of 6,7-diacyl-7-deacetylforskolin derivatives
PT81365A (en) Preparation process of new 6-phenethylaminoalkyl-furo-(3,4-c)-pyridine derivatives
CS714485A2 (en) Process for preparing derivatives of thieno- and furo/2,3-c/pyrroles
HK47392A (en) Stereospecific process for the preparation of furo(3,4-c)pyridine enantiomers,compounds thus obtained and therapeutical compositions thereof
GB8907480D0 (en) Separation of insomers of furo(3,4-c)pyridine derivatives
ZA856088B (en) New preparation process of 6-substituted-furo-(3,4-c)-pyridine derivatives
PT81087A (en) Preparation process of new 6-aminomethyl-furo-(3,4-c)-pyridine derivatives
AU7652487A (en) Process for the preparation of 2,4-diamino-5-benzylpyrimidines
GB2165242B (en) Process for the preparation of 1, 2-benzoxathiine derivatives
GB8917168D0 (en) Asymmetric synthesis of furo(3,4-c)pyridine derivatives
PT81633A (en) Process for the preparation of 1,4-dihydropiridine derivatives
PL263015A1 (en) The method of manufacture of derivatives of 6-h-indol/2,3-b/-quinoline
PL250235A2 (en) Process for preparing 2,5-dinitrate of 1,4:3,6-dianhydro-d-sorbite
BG43915A1 (en) Method for preparing of 1, 4- diiodic octafluorbutane
CS967587A1 (en) Method of 2,6-dialkyl-n-/l-methoxy-2-propyl-aniline preparation
CS490187A1 (en) Method of 2,5-dibutoxy-4-morpholine-benzendiazononium preparation
CS803287A1 (en) Method of 0,0-dimethyl-s-phthalimidomethyldithiophosphate preparation