AT385036B - Verfahren zum herstellen von neuen carboxamidoderivaten von 5h-1,3,4-thiadiazolo(3,2-a)-pyrimidinen und ihren pharmazeutisch unbedenklichen salzen - Google Patents

Verfahren zum herstellen von neuen carboxamidoderivaten von 5h-1,3,4-thiadiazolo(3,2-a)-pyrimidinen und ihren pharmazeutisch unbedenklichen salzen

Info

Publication number
AT385036B
AT385036B AT0438383A AT438383A AT385036B AT 385036 B AT385036 B AT 385036B AT 0438383 A AT0438383 A AT 0438383A AT 438383 A AT438383 A AT 438383A AT 385036 B AT385036 B AT 385036B
Authority
AT
Austria
Prior art keywords
thiadiazolo
pyrimidines
producing new
pharmaceutically safe
safe salts
Prior art date
Application number
AT0438383A
Other languages
English (en)
Other versions
ATA438383A (de
Inventor
Gianfederico Doria
Carlo Passarotti
Ada Buttinoni
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838329746A external-priority patent/GB8329746D0/en
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of ATA438383A publication Critical patent/ATA438383A/de
Application granted granted Critical
Publication of AT385036B publication Critical patent/AT385036B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
    • C07D285/125—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
    • C07D285/135—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT0438383A 1982-12-23 1983-12-15 Verfahren zum herstellen von neuen carboxamidoderivaten von 5h-1,3,4-thiadiazolo(3,2-a)-pyrimidinen und ihren pharmazeutisch unbedenklichen salzen AT385036B (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8236642 1982-12-23
GB838329746A GB8329746D0 (en) 1983-11-08 1983-11-08 Carboxamido-derivatives

Publications (2)

Publication Number Publication Date
ATA438383A ATA438383A (de) 1987-07-15
AT385036B true AT385036B (de) 1988-02-10

Family

ID=26284768

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0438383A AT385036B (de) 1982-12-23 1983-12-15 Verfahren zum herstellen von neuen carboxamidoderivaten von 5h-1,3,4-thiadiazolo(3,2-a)-pyrimidinen und ihren pharmazeutisch unbedenklichen salzen

Country Status (15)

Country Link
US (1) US4522944A (de)
AT (1) AT385036B (de)
AU (1) AU558600B2 (de)
CA (1) CA1211440A (de)
CH (1) CH657136A5 (de)
DE (1) DE3346223A1 (de)
DK (1) DK593983A (de)
FI (1) FI834698A (de)
FR (1) FR2538392B1 (de)
GR (1) GR79479B (de)
IL (1) IL70522A (de)
IT (1) IT1194521B (de)
NL (1) NL8304340A (de)
SE (1) SE454698B (de)
SU (1) SU1297731A3 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3702758A1 (de) * 1987-01-30 1988-09-29 Hoechst Ag Substituierte 3-phenyl-7h-thiazolo (3,2-b) (1,2,4) triazin-7-one, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung, sowie einige bei der herstellung der genannten verbindungen gebildete zwischenprodukte
AU2008226814C1 (en) 2007-03-12 2014-11-20 Intra-Cellular Therapies, Inc. Substituted heterocycle fused gamma-carbolines synthesis
US20150080404A1 (en) 2012-04-14 2015-03-19 Intra-Cellular Therapies, Inc. Novel compositions and methods
US9708322B2 (en) 2013-03-15 2017-07-18 Intra-Cellular Therapies, Inc. Substituted pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxalines for inhibiting serotonin reuptake transporter activity
WO2015085004A1 (en) 2013-12-03 2015-06-11 Intra-Cellular Therapies, Inc. Novel methods
WO2015154025A1 (en) 2014-04-04 2015-10-08 Intra-Cellular Therapies, Inc. Organic compounds
US9745300B2 (en) 2014-04-04 2017-08-29 Intra-Cellular Therapies, Inc. Organic compounds
PL3407888T3 (pl) 2016-01-26 2021-08-30 Intra-Cellular Therapies, Inc. Związki pirydopirolochinoksaliny, ich kompozycje i zastosowania
EP3436016B1 (de) 2016-03-28 2022-04-27 Intra-Cellular Therapies, Inc. Neuartige co-kristalle
WO2017172784A1 (en) 2016-03-28 2017-10-05 Intra-Cellular Therapies, Inc. Novel salts and crystals
US10682354B2 (en) 2016-03-28 2020-06-16 Intra-Cellular Therapies, Inc. Compositions and methods
EP3525763A4 (de) 2016-10-12 2020-06-17 Intra-Cellular Therapies, Inc. Amorphe feste dispersionen
EP3562484B1 (de) 2016-12-29 2021-08-25 Intra-Cellular Therapies, Inc. Pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxalinderivate zur behandlung von erkrankungen des zns
US10961245B2 (en) 2016-12-29 2021-03-30 Intra-Cellular Therapies, Inc. Substituted heterocycle fused gamma-carbolines for treatment of central nervous system disorders
MX2019011329A (es) 2017-03-24 2019-12-02 Intra Celular Therapies Inc Composiciones novedosas y metodos.
WO2019023063A1 (en) 2017-07-26 2019-01-31 Intra-Cellular Therapies, Inc. ORGANIC COMPOUNDS
JP7223742B2 (ja) 2017-07-26 2023-02-16 イントラ－セルラー・セラピーズ・インコーポレイテッド 有機化合物
CA3102948A1 (en) 2018-06-08 2019-12-12 Intra-Cellular Therapies, Inc. Novel methods
KR20210031455A (ko) 2018-06-11 2021-03-19 인트라-셀룰라 써래피스, 인코퍼레이티드. 치환된 헤테로환 융합 감마-카르볼린 합성
JP7457000B2 (ja) 2018-08-31 2024-03-27 イントラ－セルラー・セラピーズ・インコーポレイテッド 新規方法
CA3108553A1 (en) 2018-08-31 2020-03-05 Intra-Cellular Therapies, Inc. Novel methods
MX2022000143A (es) 2019-07-07 2022-02-17 Intra Cellular Therapies Inc Metodos novedosos.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5129981B2 (de) * 1973-07-17 1976-08-28
GB1568962A (en) * 1975-10-31 1980-06-11 Beecham Group Ltd Reparation and compositions containing them (heterocyclic-carbonylamino)pencillins methods for their p
JPS55115889A (en) * 1979-02-28 1980-09-06 Teijin Ltd 6-carbamoylthiazolo 3,2-a pyrimidine derivative and its preparation
JPS57142989A (en) * 1981-02-27 1982-09-03 Dai Ichi Seiyaku Co Ltd Thiazolopyrimidine derivative

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACT 76(1972) 59562 G *
CHEMICAL ABSTRACT 84(1976) 4010 K *

Also Published As

Publication number Publication date
DE3346223A1 (de) 1984-06-28
FR2538392B1 (fr) 1987-01-16
FI834698A0 (fi) 1983-12-20
SE8307133D0 (sv) 1983-12-22
ATA438383A (de) 1987-07-15
US4522944A (en) 1985-06-11
FI834698A (fi) 1984-06-24
AU2252583A (en) 1984-06-28
SE454698B (sv) 1988-05-24
FR2538392A1 (fr) 1984-06-29
IT1194521B (it) 1988-09-22
CH657136A5 (de) 1986-08-15
SU1297731A3 (ru) 1987-03-15
IL70522A0 (en) 1984-03-30
NL8304340A (nl) 1984-07-16
DK593983A (da) 1984-06-24
IL70522A (en) 1986-02-28
DK593983D0 (da) 1983-12-22
GR79479B (de) 1984-10-30
SE8307133L (sv) 1984-06-24
IT8324207A0 (it) 1983-12-16
CA1211440A (en) 1986-09-16
AU558600B2 (en) 1987-02-05

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