AT381096B - Verfahren zur herstellung von neuen cephemverbindungen und deren pharmazeutisch unbedenklichen salzen - Google Patents

Verfahren zur herstellung von neuen cephemverbindungen und deren pharmazeutisch unbedenklichen salzen

Info

Publication number
AT381096B
AT381096B AT0325383A AT325383A AT381096B AT 381096 B AT381096 B AT 381096B AT 0325383 A AT0325383 A AT 0325383A AT 325383 A AT325383 A AT 325383A AT 381096 B AT381096 B AT 381096B
Authority
AT
Austria
Prior art keywords
producing new
pharmaceutically safe
safe salts
cephemic
compounds
Prior art date
Application number
AT0325383A
Other languages
English (en)
Other versions
ATA325383A (de
Inventor
Takao Takaya
Hisashi Takasugi
Hideaki Yamanaka
Kenji Mivai
Yoshikazu Inoue
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838311815A external-priority patent/GB8311815D0/en
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of ATA325383A publication Critical patent/ATA325383A/de
Application granted granted Critical
Publication of AT381096B publication Critical patent/AT381096B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT0325383A 1982-09-10 1983-09-12 Verfahren zur herstellung von neuen cephemverbindungen und deren pharmazeutisch unbedenklichen salzen AT381096B (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8225836 1982-09-10
GB838311815A GB8311815D0 (en) 1983-04-29 1983-04-29 Cephem compounds

Publications (2)

Publication Number Publication Date
ATA325383A ATA325383A (de) 1986-01-15
AT381096B true AT381096B (de) 1986-08-25

Family

ID=26283800

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0325383A AT381096B (de) 1982-09-10 1983-09-12 Verfahren zur herstellung von neuen cephemverbindungen und deren pharmazeutisch unbedenklichen salzen

Country Status (8)

Country Link
US (2) US4546101A (de)
EP (1) EP0103264B1 (de)
AT (1) AT381096B (de)
CH (1) CH658862A5 (de)
DE (1) DE3380990D1 (de)
FR (1) FR2534922B1 (de)
GB (1) GB2128990B (de)
IT (1) IT1194394B (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4546101A (en) * 1982-09-10 1985-10-08 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds useful for treating infectious diseases in human being and animals and processes for preparation thereof
IE58487B1 (en) * 1984-09-07 1993-09-22 Kaisha Maiji Seika New cephalosporin compounds and the production thereof
DE3686632T2 (de) * 1985-04-30 1993-01-21 Takeda Chemical Industries Ltd Antibiotische derivate, ihre herstellung und verwendung.
JPS62205088A (ja) * 1986-03-03 1987-09-09 Meiji Seika Kaisha Ltd 新規セフエム化合物
US5073551A (en) * 1988-03-30 1991-12-17 Sagami Chemical Research Center Cephalosporin compounds
JPH0686463B2 (ja) * 1988-07-01 1994-11-02 明治製菓株式会社 新規セフェム化合物、その製造法及び抗菌剤
JPH0635464B2 (ja) * 1988-09-02 1994-05-11 明治製菓株式会社 新規セフェム化合物、その製造法及び抗菌剤
IL94946A0 (en) * 1989-07-13 1991-06-10 Eisai Co Ltd 3-substituted vinyl cephalosporin derivatives,their preparation and pharmaceutical compositions containing them
JP2895900B2 (ja) * 1990-03-08 1999-05-24 大塚化学株式会社 ３―ホルミルセフエム誘導体の製造法
US6248881B1 (en) 1991-03-08 2001-06-19 Biochemie Gmbh Intermediates and process for the production of 3-vinyl cephalosporins
WO1994010177A1 (en) * 1992-10-23 1994-05-11 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds, and their pharmaceutical compositions
CA2935651A1 (en) 2007-10-09 2009-04-16 Gladius Pharmaceuticals Corporation Broad spectrum beta-lactamase inhibitors
EA028342B1 (ru) 2011-09-09 2017-11-30 Мерк Шарп И Доум Корп. Способы лечения пневмонии
US8809314B1 (en) 2012-09-07 2014-08-19 Cubist Pharmacueticals, Inc. Cephalosporin compound
US8476425B1 (en) 2012-09-27 2013-07-02 Cubist Pharmaceuticals, Inc. Tazobactam arginine compositions
EP2968352B1 (de) 2013-03-12 2018-09-26 Gladius Pharmaceuticals Corporation Derivatisierte 3-styryl-cephalosporine
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
NZ700372A (en) 2013-03-15 2016-01-29 Merck Sharp & Dohme Ceftolozane antibiotic compositions
US20140274997A1 (en) 2013-03-15 2014-09-18 Cubist Pharmaceuticals, Inc. Cephalosporin pharmaceutical compositions
EP3043797B1 (de) 2013-09-09 2020-04-08 Merck Sharp & Dohme Corp. Behandlung von infektionen mit ceftolozan/tazobactam bei personen mit beeinträchtigter nierenfunktion
US8906898B1 (en) 2013-09-27 2014-12-09 Calixa Therapeutics, Inc. Solid forms of ceftolozane
WO2016160362A1 (en) 2015-03-31 2016-10-06 Allergan, Inc. Cyclosporins modified on the mebmt sidechain by heterocyclic rings
CN111548358A (zh) * 2020-06-18 2020-08-18 山西千岫制药有限公司 一种头孢吡普侧链中间体的合成制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3769277A (en) * 1970-01-23 1973-10-30 Glaxo Lab Ltd Preparation of delta3-4 carboxy cephalosporins having a 3-vinyl or substituted 3-vinyl group
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds
US4255423A (en) * 1977-07-27 1981-03-10 Merck & Co., Inc. Cephalosporin compounds
US4409214A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical, Co., Ltd. 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
US4507293A (en) * 1980-09-26 1985-03-26 Fujisawa Pharmaceutical Co., Ltd. Antimicrobial cephem compounds
GR75487B (de) * 1981-06-22 1984-07-23 Fujisawa Pharmaceutical Co
NL8202706A (nl) * 1981-07-15 1983-02-01 Erba Farmitalia Gesubstitueerde thiazolo3,2-apyrimidinen en werkwijzen ter bereiding ervan.
US4500526A (en) * 1982-06-28 1985-02-19 Bristol-Myers Company Cephalosporin derivatives
US4546101A (en) * 1982-09-10 1985-10-08 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds useful for treating infectious diseases in human being and animals and processes for preparation thereof
JPS60132918A (ja) * 1983-12-22 1985-07-16 Asahi Chem Ind Co Ltd 経口用セフアロスポリン組成物

Also Published As

Publication number Publication date
FR2534922A1 (fr) 1984-04-27
US4546101A (en) 1985-10-08
IT8322837A1 (it) 1985-03-09
GB2128990B (en) 1986-01-08
IT1194394B (it) 1988-09-22
GB8324081D0 (en) 1983-10-12
US4639448A (en) 1987-01-27
IT8322837A0 (it) 1983-09-09
EP0103264A3 (en) 1985-05-08
EP0103264B1 (de) 1989-12-20
ATA325383A (de) 1986-01-15
EP0103264A2 (de) 1984-03-21
FR2534922B1 (fr) 1987-01-09
GB2128990A (en) 1984-05-10
DE3380990D1 (de) 1990-01-25
CH658862A5 (de) 1986-12-15

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee