AT381096B - Verfahren zur herstellung von neuen cephemverbindungen und deren pharmazeutisch unbedenklichen salzen - Google Patents
Verfahren zur herstellung von neuen cephemverbindungen und deren pharmazeutisch unbedenklichen salzenInfo
- Publication number
- AT381096B AT381096B AT0325383A AT325383A AT381096B AT 381096 B AT381096 B AT 381096B AT 0325383 A AT0325383 A AT 0325383A AT 325383 A AT325383 A AT 325383A AT 381096 B AT381096 B AT 381096B
- Authority
- AT
- Austria
- Prior art keywords
- producing new
- pharmaceutically safe
- safe salts
- cephemic
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8225836 | 1982-09-10 | ||
GB838311815A GB8311815D0 (en) | 1983-04-29 | 1983-04-29 | Cephem compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
ATA325383A ATA325383A (de) | 1986-01-15 |
AT381096B true AT381096B (de) | 1986-08-25 |
Family
ID=26283800
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT0325383A AT381096B (de) | 1982-09-10 | 1983-09-12 | Verfahren zur herstellung von neuen cephemverbindungen und deren pharmazeutisch unbedenklichen salzen |
Country Status (8)
Country | Link |
---|---|
US (2) | US4546101A (de) |
EP (1) | EP0103264B1 (de) |
AT (1) | AT381096B (de) |
CH (1) | CH658862A5 (de) |
DE (1) | DE3380990D1 (de) |
FR (1) | FR2534922B1 (de) |
GB (1) | GB2128990B (de) |
IT (1) | IT1194394B (de) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4546101A (en) * | 1982-09-10 | 1985-10-08 | Fujisawa Pharmaceutical Co., Ltd. | New cephem compounds useful for treating infectious diseases in human being and animals and processes for preparation thereof |
IE58487B1 (en) * | 1984-09-07 | 1993-09-22 | Kaisha Maiji Seika | New cephalosporin compounds and the production thereof |
DE3686632T2 (de) * | 1985-04-30 | 1993-01-21 | Takeda Chemical Industries Ltd | Antibiotische derivate, ihre herstellung und verwendung. |
JPS62205088A (ja) * | 1986-03-03 | 1987-09-09 | Meiji Seika Kaisha Ltd | 新規セフエム化合物 |
US5073551A (en) * | 1988-03-30 | 1991-12-17 | Sagami Chemical Research Center | Cephalosporin compounds |
JPH0686463B2 (ja) * | 1988-07-01 | 1994-11-02 | 明治製菓株式会社 | 新規セフェム化合物、その製造法及び抗菌剤 |
JPH0635464B2 (ja) * | 1988-09-02 | 1994-05-11 | 明治製菓株式会社 | 新規セフェム化合物、その製造法及び抗菌剤 |
IL94946A0 (en) * | 1989-07-13 | 1991-06-10 | Eisai Co Ltd | 3-substituted vinyl cephalosporin derivatives,their preparation and pharmaceutical compositions containing them |
JP2895900B2 (ja) * | 1990-03-08 | 1999-05-24 | 大塚化学株式会社 | 3―ホルミルセフエム誘導体の製造法 |
US6248881B1 (en) | 1991-03-08 | 2001-06-19 | Biochemie Gmbh | Intermediates and process for the production of 3-vinyl cephalosporins |
WO1994010177A1 (en) * | 1992-10-23 | 1994-05-11 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds, and their pharmaceutical compositions |
CA2935651A1 (en) | 2007-10-09 | 2009-04-16 | Gladius Pharmaceuticals Corporation | Broad spectrum beta-lactamase inhibitors |
EA028342B1 (ru) | 2011-09-09 | 2017-11-30 | Мерк Шарп И Доум Корп. | Способы лечения пневмонии |
US8809314B1 (en) | 2012-09-07 | 2014-08-19 | Cubist Pharmacueticals, Inc. | Cephalosporin compound |
US8476425B1 (en) | 2012-09-27 | 2013-07-02 | Cubist Pharmaceuticals, Inc. | Tazobactam arginine compositions |
EP2968352B1 (de) | 2013-03-12 | 2018-09-26 | Gladius Pharmaceuticals Corporation | Derivatisierte 3-styryl-cephalosporine |
US9872906B2 (en) | 2013-03-15 | 2018-01-23 | Merck Sharp & Dohme Corp. | Ceftolozane antibiotic compositions |
NZ700372A (en) | 2013-03-15 | 2016-01-29 | Merck Sharp & Dohme | Ceftolozane antibiotic compositions |
US20140274997A1 (en) | 2013-03-15 | 2014-09-18 | Cubist Pharmaceuticals, Inc. | Cephalosporin pharmaceutical compositions |
EP3043797B1 (de) | 2013-09-09 | 2020-04-08 | Merck Sharp & Dohme Corp. | Behandlung von infektionen mit ceftolozan/tazobactam bei personen mit beeinträchtigter nierenfunktion |
US8906898B1 (en) | 2013-09-27 | 2014-12-09 | Calixa Therapeutics, Inc. | Solid forms of ceftolozane |
WO2016160362A1 (en) | 2015-03-31 | 2016-10-06 | Allergan, Inc. | Cyclosporins modified on the mebmt sidechain by heterocyclic rings |
CN111548358A (zh) * | 2020-06-18 | 2020-08-18 | 山西千岫制药有限公司 | 一种头孢吡普侧链中间体的合成制备方法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3769277A (en) * | 1970-01-23 | 1973-10-30 | Glaxo Lab Ltd | Preparation of delta3-4 carboxy cephalosporins having a 3-vinyl or substituted 3-vinyl group |
GB1399086A (en) * | 1971-05-14 | 1975-06-25 | Glaxo Lab Ltd | Cephalosporin compounds |
US4255423A (en) * | 1977-07-27 | 1981-03-10 | Merck & Co., Inc. | Cephalosporin compounds |
US4409214A (en) * | 1979-11-19 | 1983-10-11 | Fujisawa Pharmaceutical, Co., Ltd. | 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof |
US4507293A (en) * | 1980-09-26 | 1985-03-26 | Fujisawa Pharmaceutical Co., Ltd. | Antimicrobial cephem compounds |
GR75487B (de) * | 1981-06-22 | 1984-07-23 | Fujisawa Pharmaceutical Co | |
NL8202706A (nl) * | 1981-07-15 | 1983-02-01 | Erba Farmitalia | Gesubstitueerde thiazolo3,2-apyrimidinen en werkwijzen ter bereiding ervan. |
US4500526A (en) * | 1982-06-28 | 1985-02-19 | Bristol-Myers Company | Cephalosporin derivatives |
US4546101A (en) * | 1982-09-10 | 1985-10-08 | Fujisawa Pharmaceutical Co., Ltd. | New cephem compounds useful for treating infectious diseases in human being and animals and processes for preparation thereof |
JPS60132918A (ja) * | 1983-12-22 | 1985-07-16 | Asahi Chem Ind Co Ltd | 経口用セフアロスポリン組成物 |
-
1983
- 1983-09-02 US US06/528,796 patent/US4546101A/en not_active Expired - Fee Related
- 1983-09-05 CH CH4853/83A patent/CH658862A5/de not_active IP Right Cessation
- 1983-09-06 FR FR8314220A patent/FR2534922B1/fr not_active Expired
- 1983-09-07 DE DE8383108795T patent/DE3380990D1/de not_active Expired - Fee Related
- 1983-09-07 EP EP83108795A patent/EP0103264B1/de not_active Expired
- 1983-09-08 GB GB08324081A patent/GB2128990B/en not_active Expired
- 1983-09-09 IT IT22837/83A patent/IT1194394B/it active
- 1983-09-12 AT AT0325383A patent/AT381096B/de not_active IP Right Cessation
-
1985
- 1985-06-04 US US06/741,267 patent/US4639448A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
FR2534922A1 (fr) | 1984-04-27 |
US4546101A (en) | 1985-10-08 |
IT8322837A1 (it) | 1985-03-09 |
GB2128990B (en) | 1986-01-08 |
IT1194394B (it) | 1988-09-22 |
GB8324081D0 (en) | 1983-10-12 |
US4639448A (en) | 1987-01-27 |
IT8322837A0 (it) | 1983-09-09 |
EP0103264A3 (en) | 1985-05-08 |
EP0103264B1 (de) | 1989-12-20 |
ATA325383A (de) | 1986-01-15 |
EP0103264A2 (de) | 1984-03-21 |
FR2534922B1 (fr) | 1987-01-09 |
GB2128990A (en) | 1984-05-10 |
DE3380990D1 (de) | 1990-01-25 |
CH658862A5 (de) | 1986-12-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ELJ | Ceased due to non-payment of the annual fee |