IT1194394B - Cefem-derivati e procedimenti per la loro preparazione - Google Patents

Cefem-derivati e procedimenti per la loro preparazione

Info

Publication number
IT1194394B
IT1194394B IT22837/83A IT2283783A IT1194394B IT 1194394 B IT1194394 B IT 1194394B IT 22837/83 A IT22837/83 A IT 22837/83A IT 2283783 A IT2283783 A IT 2283783A IT 1194394 B IT1194394 B IT 1194394B
Authority
IT
Italy
Prior art keywords
cefem
procedures
derivatives
preparation
Prior art date
Application number
IT22837/83A
Other languages
English (en)
Other versions
IT8322837A0 (it
IT8322837A1 (it
Inventor
Takaya Takao
Takasugi Hisashi
Yamanaka Hideaki
Miyai Kenji
Inoue Yoshikazu
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838311815A external-priority patent/GB8311815D0/en
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of IT8322837A0 publication Critical patent/IT8322837A0/it
Publication of IT8322837A1 publication Critical patent/IT8322837A1/it
Application granted granted Critical
Publication of IT1194394B publication Critical patent/IT1194394B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT22837/83A 1982-09-10 1983-09-09 Cefem-derivati e procedimenti per la loro preparazione IT1194394B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8225836 1982-09-10
GB838311815A GB8311815D0 (en) 1983-04-29 1983-04-29 Cephem compounds

Publications (3)

Publication Number Publication Date
IT8322837A0 IT8322837A0 (it) 1983-09-09
IT8322837A1 IT8322837A1 (it) 1985-03-09
IT1194394B true IT1194394B (it) 1988-09-22

Family

ID=26283800

Family Applications (1)

Application Number Title Priority Date Filing Date
IT22837/83A IT1194394B (it) 1982-09-10 1983-09-09 Cefem-derivati e procedimenti per la loro preparazione

Country Status (8)

Country Link
US (2) US4546101A (it)
EP (1) EP0103264B1 (it)
AT (1) AT381096B (it)
CH (1) CH658862A5 (it)
DE (1) DE3380990D1 (it)
FR (1) FR2534922B1 (it)
GB (1) GB2128990B (it)
IT (1) IT1194394B (it)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4546101A (en) * 1982-09-10 1985-10-08 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds useful for treating infectious diseases in human being and animals and processes for preparation thereof
IE58487B1 (en) * 1984-09-07 1993-09-22 Kaisha Maiji Seika New cephalosporin compounds and the production thereof
EP0219923B1 (en) * 1985-04-30 1992-09-02 Takeda Chemical Industries, Ltd. Antibiotic derivatives, their production and use
JPS62205088A (ja) * 1986-03-03 1987-09-09 Meiji Seika Kaisha Ltd 新規セフエム化合物
US5073551A (en) * 1988-03-30 1991-12-17 Sagami Chemical Research Center Cephalosporin compounds
JPH0686463B2 (ja) * 1988-07-01 1994-11-02 明治製菓株式会社 新規セフェム化合物、その製造法及び抗菌剤
JPH0635464B2 (ja) * 1988-09-02 1994-05-11 明治製菓株式会社 新規セフェム化合物、その製造法及び抗菌剤
IL94946A0 (en) * 1989-07-13 1991-06-10 Eisai Co Ltd 3-substituted vinyl cephalosporin derivatives,their preparation and pharmaceutical compositions containing them
JP2895900B2 (ja) * 1990-03-08 1999-05-24 大塚化学株式会社 ３―ホルミルセフエム誘導体の製造法
US6248881B1 (en) 1991-03-08 2001-06-19 Biochemie Gmbh Intermediates and process for the production of 3-vinyl cephalosporins
KR950704331A (ko) * 1992-07-12 1995-11-17 후지야마 아키라 세펨 화합물 및 그의 약제학적 조성물(cephem compounds and their pharmaceutical compositions)
EP2209474A4 (en) 2007-10-09 2013-07-24 Sopharmia Inc BROAD SPECTRUM BETA-LACTAMASE INHIBITORS
US20130065874A1 (en) 2011-09-09 2013-03-14 Cubist Pharmaceuticals, Inc. Methods for treating intrapulmonary infections
US8809314B1 (en) 2012-09-07 2014-08-19 Cubist Pharmacueticals, Inc. Cephalosporin compound
US8476425B1 (en) 2012-09-27 2013-07-02 Cubist Pharmaceuticals, Inc. Tazobactam arginine compositions
US9975905B2 (en) 2013-03-12 2018-05-22 Gladius Pharmaceuticals Corporation Derivatized 3-styryl-cephalosporins
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
US20140274991A1 (en) 2013-03-15 2014-09-18 Cubist Pharmaceuticals, Inc. Ceftolozane pharmaceutical compositions
CA2906151A1 (en) 2013-03-15 2014-09-18 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
ES2800603T3 (es) 2013-09-09 2021-01-04 Merck Sharp & Dohme Tratamiento de infecciones con ceftolozano/tazobactam en sujetos con insuficiencia renal
US8906898B1 (en) 2013-09-27 2014-12-09 Calixa Therapeutics, Inc. Solid forms of ceftolozane
EP3277704A1 (en) 2015-03-31 2018-02-07 Allergan, Inc. Cyclosporins modified on the mebmt sidechain by heterocyclic rings
CN111548358A (zh) * 2020-06-18 2020-08-18 山西千岫制药有限公司 一种头孢吡普侧链中间体的合成制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3769277A (en) * 1970-01-23 1973-10-30 Glaxo Lab Ltd Preparation of delta3-4 carboxy cephalosporins having a 3-vinyl or substituted 3-vinyl group
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds
US4255423A (en) * 1977-07-27 1981-03-10 Merck & Co., Inc. Cephalosporin compounds
US4409214A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical, Co., Ltd. 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
US4507293A (en) * 1980-09-26 1985-03-26 Fujisawa Pharmaceutical Co., Ltd. Antimicrobial cephem compounds
GR75487B (it) * 1981-06-22 1984-07-23 Fujisawa Pharmaceutical Co
AU551718B2 (en) * 1981-07-15 1986-05-08 Farmitalia Carlo Erba S.P.A. Substituted thiazolo(3,2-alpha)pyrimidines
US4500526A (en) * 1982-06-28 1985-02-19 Bristol-Myers Company Cephalosporin derivatives
US4546101A (en) * 1982-09-10 1985-10-08 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds useful for treating infectious diseases in human being and animals and processes for preparation thereof
JPS60132918A (ja) * 1983-12-22 1985-07-16 Asahi Chem Ind Co Ltd 経口用セフアロスポリン組成物

Also Published As

Publication number Publication date
AT381096B (de) 1986-08-25
ATA325383A (de) 1986-01-15
EP0103264A2 (en) 1984-03-21
FR2534922A1 (fr) 1984-04-27
FR2534922B1 (fr) 1987-01-09
IT8322837A0 (it) 1983-09-09
GB2128990A (en) 1984-05-10
GB8324081D0 (en) 1983-10-12
IT8322837A1 (it) 1985-03-09
GB2128990B (en) 1986-01-08
EP0103264A3 (en) 1985-05-08
CH658862A5 (de) 1986-12-15
EP0103264B1 (en) 1989-12-20
US4546101A (en) 1985-10-08
US4639448A (en) 1987-01-27
DE3380990D1 (de) 1990-01-25

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Legal Events

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19930929