DE3380990D1 - Cephalosporinverbindungen und verfahren zu ihrer herstellung. - Google Patents

Cephalosporinverbindungen und verfahren zu ihrer herstellung.

Info

Publication number
DE3380990D1
DE3380990D1 DE8383108795T DE3380990T DE3380990D1 DE 3380990 D1 DE3380990 D1 DE 3380990D1 DE 8383108795 T DE8383108795 T DE 8383108795T DE 3380990 T DE3380990 T DE 3380990T DE 3380990 D1 DE3380990 D1 DE 3380990D1
Authority
DE
Germany
Prior art keywords
production
cephalosporine compounds
cephalosporine
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8383108795T
Other languages
English (en)
Inventor
Takao Takaya
Hisashi Takasugi
Hideaki Yamanaka
Kenji Miyai
Yoshikazu Inoue
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838311815A external-priority patent/GB8311815D0/en
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE3380990D1 publication Critical patent/DE3380990D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE8383108795T 1982-09-10 1983-09-07 Cephalosporinverbindungen und verfahren zu ihrer herstellung. Expired - Fee Related DE3380990D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8225836 1982-09-10
GB838311815A GB8311815D0 (en) 1983-04-29 1983-04-29 Cephem compounds

Publications (1)

Publication Number Publication Date
DE3380990D1 true DE3380990D1 (de) 1990-01-25

Family

ID=26283800

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8383108795T Expired - Fee Related DE3380990D1 (de) 1982-09-10 1983-09-07 Cephalosporinverbindungen und verfahren zu ihrer herstellung.

Country Status (8)

Country Link
US (2) US4546101A (de)
EP (1) EP0103264B1 (de)
AT (1) AT381096B (de)
CH (1) CH658862A5 (de)
DE (1) DE3380990D1 (de)
FR (1) FR2534922B1 (de)
GB (1) GB2128990B (de)
IT (1) IT1194394B (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4546101A (en) * 1982-09-10 1985-10-08 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds useful for treating infectious diseases in human being and animals and processes for preparation thereof
IE58487B1 (en) * 1984-09-07 1993-09-22 Kaisha Maiji Seika New cephalosporin compounds and the production thereof
EP0219923B1 (de) * 1985-04-30 1992-09-02 Takeda Chemical Industries, Ltd. Antibiotische Derivate, ihre Herstellung und Verwendung
JPS62205088A (ja) * 1986-03-03 1987-09-09 Meiji Seika Kaisha Ltd 新規セフエム化合物
US5073551A (en) * 1988-03-30 1991-12-17 Sagami Chemical Research Center Cephalosporin compounds
JPH0686463B2 (ja) * 1988-07-01 1994-11-02 明治製菓株式会社 新規セフェム化合物、その製造法及び抗菌剤
JPH0635464B2 (ja) * 1988-09-02 1994-05-11 明治製菓株式会社 新規セフェム化合物、その製造法及び抗菌剤
IL94946A0 (en) * 1989-07-13 1991-06-10 Eisai Co Ltd 3-substituted vinyl cephalosporin derivatives,their preparation and pharmaceutical compositions containing them
JP2895900B2 (ja) * 1990-03-08 1999-05-24 大塚化学株式会社 ３―ホルミルセフエム誘導体の製造法
US6248881B1 (en) 1991-03-08 2001-06-19 Biochemie Gmbh Intermediates and process for the production of 3-vinyl cephalosporins
CA2147609A1 (en) * 1992-10-23 1994-05-11 Kohji Kawabata Cephem compounds, and their pharmaceutical compositions
EP2209474A4 (de) 2007-10-09 2013-07-24 Sopharmia Inc Breitband-beta-lactamase-hemmer
EP2862569A1 (de) 2011-09-09 2015-04-22 Cubist Pharmaceuticals, Inc. Verfahren zur Behandlung von intrapulmonalen Infektionen
US8809314B1 (en) 2012-09-07 2014-08-19 Cubist Pharmacueticals, Inc. Cephalosporin compound
US8476425B1 (en) 2012-09-27 2013-07-02 Cubist Pharmaceuticals, Inc. Tazobactam arginine compositions
WO2014165126A2 (en) 2013-03-12 2014-10-09 Sopharmia, Inc. Derivatized 3-styryl-cephalosporins
KR102226197B1 (ko) 2013-03-15 2021-03-11 머크 샤프 앤드 돔 코포레이션 세프톨로잔 항균성 조성물
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
US9320740B2 (en) 2013-03-15 2016-04-26 Merck Sharp & Dohme Corp. Ceftolozane-tazobactam pharmaceutical compositions
WO2015035376A2 (en) 2013-09-09 2015-03-12 Calixa Therapeutics, Inc. Treating infections with ceftolozane/tazobactam in subjects having impaired renal function
US20150094293A1 (en) 2013-09-27 2015-04-02 Calixa Therapeutics, Inc. Solid forms of ceftolozane
EP3277704A1 (de) 2015-03-31 2018-02-07 Allergan, Inc. An der mebmt-seitenkette durch heterocyclische ringe modifizierte cyclosporine
CN111548358A (zh) * 2020-06-18 2020-08-18 山西千岫制药有限公司 一种头孢吡普侧链中间体的合成制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3769277A (en) * 1970-01-23 1973-10-30 Glaxo Lab Ltd Preparation of delta3-4 carboxy cephalosporins having a 3-vinyl or substituted 3-vinyl group
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds
US4255423A (en) * 1977-07-27 1981-03-10 Merck & Co., Inc. Cephalosporin compounds
US4409214A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical, Co., Ltd. 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
US4507293A (en) * 1980-09-26 1985-03-26 Fujisawa Pharmaceutical Co., Ltd. Antimicrobial cephem compounds
GR75487B (de) * 1981-06-22 1984-07-23 Fujisawa Pharmaceutical Co
AU551718B2 (en) * 1981-07-15 1986-05-08 Farmitalia Carlo Erba S.P.A. Substituted thiazolo(3,2-alpha)pyrimidines
US4500526A (en) * 1982-06-28 1985-02-19 Bristol-Myers Company Cephalosporin derivatives
US4546101A (en) * 1982-09-10 1985-10-08 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds useful for treating infectious diseases in human being and animals and processes for preparation thereof
JPS60132918A (ja) * 1983-12-22 1985-07-16 Asahi Chem Ind Co Ltd 経口用セフアロスポリン組成物

Also Published As

Publication number Publication date
US4546101A (en) 1985-10-08
EP0103264A2 (de) 1984-03-21
EP0103264A3 (en) 1985-05-08
GB2128990A (en) 1984-05-10
FR2534922B1 (fr) 1987-01-09
ATA325383A (de) 1986-01-15
US4639448A (en) 1987-01-27
AT381096B (de) 1986-08-25
FR2534922A1 (fr) 1984-04-27
IT1194394B (it) 1988-09-22
IT8322837A0 (it) 1983-09-09
GB8324081D0 (en) 1983-10-12
EP0103264B1 (de) 1989-12-20
GB2128990B (en) 1986-01-08
CH658862A5 (de) 1986-12-15
IT8322837A1 (it) 1985-03-09

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee