FR2534922B1 - Procede de preparation de composes de cephem et nouveaux produits ainsi que les compositions pharmaceutiques les renfermant - Google Patents

Procede de preparation de composes de cephem et nouveaux produits ainsi que les compositions pharmaceutiques les renfermant

Info

Publication number
FR2534922B1
FR2534922B1 FR8314220A FR8314220A FR2534922B1 FR 2534922 B1 FR2534922 B1 FR 2534922B1 FR 8314220 A FR8314220 A FR 8314220A FR 8314220 A FR8314220 A FR 8314220A FR 2534922 B1 FR2534922 B1 FR 2534922B1
Authority
FR
France
Prior art keywords
preparation
well
pharmaceutical compositions
compositions containing
new products
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8314220A
Other languages
English (en)
Other versions
FR2534922A1 (fr
Inventor
Takao Takaya
Hisashi Takasugi
Hideaki Yamanaka
Kenji Miyai
Yoshikazu Inoue
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838311815A external-priority patent/GB8311815D0/en
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of FR2534922A1 publication Critical patent/FR2534922A1/fr
Application granted granted Critical
Publication of FR2534922B1 publication Critical patent/FR2534922B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR8314220A 1982-09-10 1983-09-06 Procede de preparation de composes de cephem et nouveaux produits ainsi que les compositions pharmaceutiques les renfermant Expired FR2534922B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8225836 1982-09-10
GB838311815A GB8311815D0 (en) 1983-04-29 1983-04-29 Cephem compounds

Publications (2)

Publication Number Publication Date
FR2534922A1 FR2534922A1 (fr) 1984-04-27
FR2534922B1 true FR2534922B1 (fr) 1987-01-09

Family

ID=26283800

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8314220A Expired FR2534922B1 (fr) 1982-09-10 1983-09-06 Procede de preparation de composes de cephem et nouveaux produits ainsi que les compositions pharmaceutiques les renfermant

Country Status (8)

Country Link
US (2) US4546101A (fr)
EP (1) EP0103264B1 (fr)
AT (1) AT381096B (fr)
CH (1) CH658862A5 (fr)
DE (1) DE3380990D1 (fr)
FR (1) FR2534922B1 (fr)
GB (1) GB2128990B (fr)
IT (1) IT1194394B (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4546101A (en) * 1982-09-10 1985-10-08 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds useful for treating infectious diseases in human being and animals and processes for preparation thereof
IE58487B1 (en) * 1984-09-07 1993-09-22 Kaisha Maiji Seika New cephalosporin compounds and the production thereof
EP0219923B1 (fr) * 1985-04-30 1992-09-02 Takeda Chemical Industries, Ltd. Dérivés antibiotiques, leur préparation et leur application
JPS62205088A (ja) * 1986-03-03 1987-09-09 Meiji Seika Kaisha Ltd 新規セフエム化合物
US5073551A (en) * 1988-03-30 1991-12-17 Sagami Chemical Research Center Cephalosporin compounds
JPH0686463B2 (ja) * 1988-07-01 1994-11-02 明治製菓株式会社 新規セフェム化合物、その製造法及び抗菌剤
JPH0635464B2 (ja) * 1988-09-02 1994-05-11 明治製菓株式会社 新規セフェム化合物、その製造法及び抗菌剤
IL94946A0 (en) * 1989-07-13 1991-06-10 Eisai Co Ltd 3-substituted vinyl cephalosporin derivatives,their preparation and pharmaceutical compositions containing them
JP2895900B2 (ja) * 1990-03-08 1999-05-24 大塚化学株式会社 ３―ホルミルセフエム誘導体の製造法
US6248881B1 (en) 1991-03-08 2001-06-19 Biochemie Gmbh Intermediates and process for the production of 3-vinyl cephalosporins
WO1994010177A1 (fr) * 1992-10-23 1994-05-11 Fujisawa Pharmaceutical Co., Ltd. Composes de cepheme et leurs compositions pharmaceutiques
EP2209474A4 (fr) 2007-10-09 2013-07-24 Sopharmia Inc Inhibiteurs de bêta-lactamase à large spectre
EP3616695A1 (fr) 2011-09-09 2020-03-04 Merck Sharp & Dohme Corp. Procédés de traitement des infections intrapulmonaires
US8809314B1 (en) 2012-09-07 2014-08-19 Cubist Pharmacueticals, Inc. Cephalosporin compound
US8476425B1 (en) 2012-09-27 2013-07-02 Cubist Pharmaceuticals, Inc. Tazobactam arginine compositions
EP3441071A1 (fr) 2013-03-12 2019-02-13 Gladius Pharmaceuticals Corporation Céphalosporines dérivées
KR102329764B1 (ko) 2013-03-15 2021-11-23 머크 샤프 앤드 돔 코포레이션 세프톨로잔 항균성 조성물
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
US20140274991A1 (en) 2013-03-15 2014-09-18 Cubist Pharmaceuticals, Inc. Ceftolozane pharmaceutical compositions
EP3043797B1 (fr) 2013-09-09 2020-04-08 Merck Sharp & Dohme Corp. Traitement d'infections au moyen de ceftolozane/tazobactam chez des sujets ayant une fonction rénale altérée
US20150094293A1 (en) 2013-09-27 2015-04-02 Calixa Therapeutics, Inc. Solid forms of ceftolozane
US10077289B2 (en) 2015-03-31 2018-09-18 Allergan, Inc. Cyclosporins modified on the MeBmt sidechain by heterocyclic rings
CN111548358A (zh) * 2020-06-18 2020-08-18 山西千岫制药有限公司 一种头孢吡普侧链中间体的合成制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3769277A (en) * 1970-01-23 1973-10-30 Glaxo Lab Ltd Preparation of delta3-4 carboxy cephalosporins having a 3-vinyl or substituted 3-vinyl group
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds
US4255423A (en) * 1977-07-27 1981-03-10 Merck & Co., Inc. Cephalosporin compounds
US4409214A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical, Co., Ltd. 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
US4507293A (en) * 1980-09-26 1985-03-26 Fujisawa Pharmaceutical Co., Ltd. Antimicrobial cephem compounds
GR75487B (fr) * 1981-06-22 1984-07-23 Fujisawa Pharmaceutical Co
NL8202706A (nl) * 1981-07-15 1983-02-01 Erba Farmitalia Gesubstitueerde thiazolo3,2-apyrimidinen en werkwijzen ter bereiding ervan.
US4500526A (en) * 1982-06-28 1985-02-19 Bristol-Myers Company Cephalosporin derivatives
US4546101A (en) * 1982-09-10 1985-10-08 Fujisawa Pharmaceutical Co., Ltd. New cephem compounds useful for treating infectious diseases in human being and animals and processes for preparation thereof
JPS60132918A (ja) * 1983-12-22 1985-07-16 Asahi Chem Ind Co Ltd 経口用セフアロスポリン組成物

Also Published As

Publication number Publication date
IT8322837A0 (it) 1983-09-09
US4546101A (en) 1985-10-08
FR2534922A1 (fr) 1984-04-27
EP0103264A3 (en) 1985-05-08
IT8322837A1 (it) 1985-03-09
DE3380990D1 (de) 1990-01-25
EP0103264B1 (fr) 1989-12-20
CH658862A5 (de) 1986-12-15
EP0103264A2 (fr) 1984-03-21
ATA325383A (de) 1986-01-15
GB8324081D0 (en) 1983-10-12
AT381096B (de) 1986-08-25
GB2128990A (en) 1984-05-10
IT1194394B (it) 1988-09-22
US4639448A (en) 1987-01-27
GB2128990B (en) 1986-01-08

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Legal Events

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ST Notification of lapse