IT8224456A0 - Prostacicline e procedimento per laloro preparazione - Google Patents

Prostacicline e procedimento per laloro preparazione

Info

Publication number
IT8224456A0
IT8224456A0 IT8224456A IT2445682A IT8224456A0 IT 8224456 A0 IT8224456 A0 IT 8224456A0 IT 8224456 A IT8224456 A IT 8224456A IT 2445682 A IT2445682 A IT 2445682A IT 8224456 A0 IT8224456 A0 IT 8224456A0
Authority
IT
Italy
Prior art keywords
prostaciclines
procedure
preparation
Prior art date
Application number
IT8224456A
Other languages
English (en)
Other versions
IT1191102B (it
IT8224456A1 (it
Inventor
Jorge Casals Stenzel
Robert Nickolson
Martin Haberey
Helmut Vorburggen
Original Assignee
Schering Ag
Fed
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag, Fed filed Critical Schering Ag
Publication of IT8224456A0 publication Critical patent/IT8224456A0/it
Publication of IT8224456A1 publication Critical patent/IT8224456A1/it
Application granted granted Critical
Publication of IT1191102B publication Critical patent/IT1191102B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0033Analogues having the carboxyl group in the side-chains replaced by other functional groups containing sulfur
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/09Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/377Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
    • C07C51/38Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups by decarboxylation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C55/00Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
    • C07C55/32Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4015Esters of acyclic unsaturated acids
IT24456/82A 1981-11-27 1982-11-26 Prostacicline e procedimento per la loro preparazione IT1191102B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813147714 DE3147714A1 (de) 1981-11-27 1981-11-27 Neue prostacycline und verfahren zu ihrer herstellung

Publications (3)

Publication Number Publication Date
IT8224456A0 true IT8224456A0 (it) 1982-11-26
IT8224456A1 IT8224456A1 (it) 1984-05-26
IT1191102B IT1191102B (it) 1988-02-24

Family

ID=6147721

Family Applications (1)

Application Number Title Priority Date Filing Date
IT24456/82A IT1191102B (it) 1981-11-27 1982-11-26 Prostacicline e procedimento per la loro preparazione

Country Status (12)

Country Link
US (1) US4532236A (it)
EP (1) EP0094951B1 (it)
JP (1) JPS58501997A (it)
AT (1) ATE16284T1 (it)
AU (1) AU570620B2 (it)
DE (2) DE3147714A1 (it)
DK (1) DK325083D0 (it)
ES (1) ES517746A1 (it)
GR (1) GR77034B (it)
HU (1) HU194850B (it)
IT (1) IT1191102B (it)
WO (1) WO1983001951A1 (it)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8204244L (sv) * 1982-07-09 1984-01-10 Ulf Schroder Kristalliserad kolhydratsmatris for biologiskt aktiva substanser
US4880939A (en) * 1986-12-11 1989-11-14 Toray Industries 2,5,6,7-tetranor-18,18,19,19-tetradehydro-4,8-inter-m-phenylene PGI2 derivatives
ATE315559T1 (de) * 2001-08-01 2006-02-15 Basell Polyolefine Gmbh Verfahren zur herstellung von heterocyclischen pentalen derivaten
ATE355263T1 (de) 2002-12-09 2006-03-15 Asahi Glass Co Ltd Verfahren zur herstellung von(4e)-5-chloro-2- isopropyl-4-pentensäureester und optischaktivem isomer davon

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6823181A (en) * 1976-05-11 1981-06-25 Wellcome Foundation Limited, The Prostacyclin salts
DE2902809A1 (de) * 1979-01-25 1980-08-07 Hoechst Ag Neue analoga von prostacyclin
US4256883A (en) * 1979-03-14 1981-03-17 Research Corporation Pyridoza prostacyclin analogues and N-oxides thereof
AU7808981A (en) * 1980-11-24 1982-06-17 G. Brown & Co. (Marine) Ltd Azimuthal mooring material handling terminal and tower

Also Published As

Publication number Publication date
WO1983001951A1 (en) 1983-06-09
AU9124782A (en) 1983-06-17
GR77034B (it) 1984-09-04
ATE16284T1 (de) 1985-11-15
EP0094951A1 (de) 1983-11-30
US4532236A (en) 1985-07-30
HU194850B (en) 1988-03-28
AU570620B2 (en) 1988-03-24
IT1191102B (it) 1988-02-24
ES517746A1 (es) 1983-08-16
EP0094951B1 (de) 1985-10-30
DK325083A (da) 1983-07-14
IT8224456A1 (it) 1984-05-26
DE3267181D1 (en) 1985-12-05
DK325083D0 (da) 1983-07-14
JPS58501997A (ja) 1983-11-24
DE3147714A1 (de) 1983-06-01

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