IT8224456A0 - Prostacicline e procedimento per laloro preparazione - Google Patents

Prostacicline e procedimento per laloro preparazione

Info

Publication number
IT8224456A0
IT8224456A0 IT8224456A IT2445682A IT8224456A0 IT 8224456 A0 IT8224456 A0 IT 8224456A0 IT 8224456 A IT8224456 A IT 8224456A IT 2445682 A IT2445682 A IT 2445682A IT 8224456 A0 IT8224456 A0 IT 8224456A0
Authority
IT
Italy
Prior art keywords
prostaciclines
procedure
preparation
Prior art date
Application number
IT8224456A
Other languages
English (en)
Other versions
IT1191102B (it
IT8224456A1 (it
Inventor
Jorge Casals Stenzel
Robert Nickolson
Martin Haberey
Helmut Vorburggen
Original Assignee
Schering Ag
Fed
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag, Fed filed Critical Schering Ag
Publication of IT8224456A0 publication Critical patent/IT8224456A0/it
Publication of IT8224456A1 publication Critical patent/IT8224456A1/it
Application granted granted Critical
Publication of IT1191102B publication Critical patent/IT1191102B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0033Analogues having the carboxyl group in the side-chains replaced by other functional groups containing sulfur
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/09Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/377Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
    • C07C51/38Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups by decarboxylation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C55/00Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
    • C07C55/32Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4015Esters of acyclic unsaturated acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT24456/82A 1981-11-27 1982-11-26 Prostacicline e procedimento per la loro preparazione IT1191102B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813147714 DE3147714A1 (de) 1981-11-27 1981-11-27 Neue prostacycline und verfahren zu ihrer herstellung

Publications (3)

Publication Number Publication Date
IT8224456A0 true IT8224456A0 (it) 1982-11-26
IT8224456A1 IT8224456A1 (it) 1984-05-26
IT1191102B IT1191102B (it) 1988-02-24

Family

ID=6147721

Family Applications (1)

Application Number Title Priority Date Filing Date
IT24456/82A IT1191102B (it) 1981-11-27 1982-11-26 Prostacicline e procedimento per la loro preparazione

Country Status (12)

Country Link
US (1) US4532236A (it)
EP (1) EP0094951B1 (it)
JP (1) JPS58501997A (it)
AT (1) ATE16284T1 (it)
AU (1) AU570620B2 (it)
DE (2) DE3147714A1 (it)
DK (1) DK325083D0 (it)
ES (1) ES517746A1 (it)
GR (1) GR77034B (it)
HU (1) HU194850B (it)
IT (1) IT1191102B (it)
WO (1) WO1983001951A1 (it)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8204244L (sv) * 1982-07-09 1984-01-10 Ulf Schroder Kristalliserad kolhydratsmatris for biologiskt aktiva substanser
US4880939A (en) * 1986-12-11 1989-11-14 Toray Industries 2,5,6,7-tetranor-18,18,19,19-tetradehydro-4,8-inter-m-phenylene PGI2 derivatives
EP1412347B1 (en) * 2001-08-01 2006-01-11 Basell Polyolefine GmbH Process for the preparation of heterocyclic pentalene derivatives
JP4645986B2 (ja) * 2002-12-09 2011-03-09 旭硝子株式会社 (4e)−5−クロロ−2−イソプロピル−4−ペンテン酸エステルおよびその光学活性体の製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6823181A (en) * 1976-05-11 1981-06-25 Wellcome Foundation Limited, The Prostacyclin salts
DE2902809A1 (de) * 1979-01-25 1980-08-07 Hoechst Ag Neue analoga von prostacyclin
US4256883A (en) * 1979-03-14 1981-03-17 Research Corporation Pyridoza prostacyclin analogues and N-oxides thereof
AU7808981A (en) * 1980-11-24 1982-06-17 G. Brown & Co. (Marine) Ltd Azimuthal mooring material handling terminal and tower

Also Published As

Publication number Publication date
GR77034B (it) 1984-09-04
EP0094951A1 (de) 1983-11-30
DK325083A (da) 1983-07-14
AU9124782A (en) 1983-06-17
IT1191102B (it) 1988-02-24
IT8224456A1 (it) 1984-05-26
ATE16284T1 (de) 1985-11-15
HU194850B (en) 1988-03-28
DE3267181D1 (en) 1985-12-05
EP0094951B1 (de) 1985-10-30
US4532236A (en) 1985-07-30
WO1983001951A1 (fr) 1983-06-09
AU570620B2 (en) 1988-03-24
JPS58501997A (ja) 1983-11-24
ES517746A1 (es) 1983-08-16
DK325083D0 (da) 1983-07-14
DE3147714A1 (de) 1983-06-01

Similar Documents

Publication Publication Date Title
IT8149656A0 (it) Composti benzoeterociclici e procedimento per prepararli
FI832589L (fi) Med kallt vatten haerdbart ortopediskt stoedfoerband
FI832233L (fi) Nappflaska med luftintagsventil
FI831902L (fi) Personsoekningsanordning med indikering foer olaesta meddelanden
RO86213A (ro) Procedeu pentru prepararea izobutenei
FI813911L (fi) Kirurgiskt foerbindningsinstrument
FI822754L (fi) Aonggenerator med oeverhettarroervaeggar
IT1167782B (it) Chinossalin-2-il-etenil-chetoni e procedimento per la loro preparazione
DK152219C (da) Azopigmentpraeparater
FI823176A0 (fi) Spritsroer med flackstraoldyser
IT1156478B (it) Procedimento per la preparazione di acril e metacril ammidi
MX155064A (es) Procedimiento de preparacion de metafenilendiaminas
RO85392A (ro) Procedeu pentru prepararea & haloalchilamide
DK435382A (da) Praeparater med langvarig frigoerelse
NO824312L (no) 4-cyano-2-azetidinoner og fremgangsmaate for deres fremstilling
IT8224456A0 (it) Prostacicline e procedimento per laloro preparazione
IT1157058B (it) Procedimento per la preparazione di acril e metaacrilamidi n.sostituite
FI834289A0 (fi) Medbringare foer en draganordning
ES527737A0 (es) Procedimiento de preparacion de dinucleosidos-monofosfatos
FI824100A0 (fi) Tystgaoende diskmaskin med liten vattenfoerbrukning
MX157260A (es) Procedimiento para preparar prostaglandinas y prostaciclinas
FI832672A7 (fi) Lääkintämenetelmä ja -valmiste.
RO89014A (ro) Procedeu pentru obtinerea ferocromului
IT1198416B (it) Procedimento di preparazione di mononitroclorobenzene
FI823320A0 (fi) Med daempningsorgan foersedd svaengdoerrslutare