AT361475B - Verfahren zur herstellung von neuen substi- tuierten imidazo(1,2-a)pyridinverbidnungen und ihren salzen - Google Patents
Verfahren zur herstellung von neuen substi- tuierten imidazo(1,2-a)pyridinverbidnungen und ihren salzenInfo
- Publication number
- AT361475B AT361475B AT901876A AT901876A AT361475B AT 361475 B AT361475 B AT 361475B AT 901876 A AT901876 A AT 901876A AT 901876 A AT901876 A AT 901876A AT 361475 B AT361475 B AT 361475B
- Authority
- AT
- Austria
- Prior art keywords
- salts
- pyridine compounds
- producing new
- new substituted
- substituted imidazo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/42—Radicals substituted by singly-bound nitrogen atoms having hetero atoms attached to the substituent nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/53—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/86—Hydrazides; Thio or imino analogues thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63903475A | 1975-12-09 | 1975-12-09 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA901876A ATA901876A (de) | 1980-08-15 |
| AT361475B true AT361475B (de) | 1981-03-10 |
Family
ID=24562456
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT901876A AT361475B (de) | 1975-12-09 | 1976-12-06 | Verfahren zur herstellung von neuen substi- tuierten imidazo(1,2-a)pyridinverbidnungen und ihren salzen |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US4096264A (de) |
| JP (1) | JPS5273896A (de) |
| AR (1) | AR222960A1 (de) |
| AT (1) | AT361475B (de) |
| AU (1) | AU505045B2 (de) |
| BE (1) | BE849123A (de) |
| CA (1) | CA1084930A (de) |
| CH (1) | CH626362A5 (de) |
| DE (1) | DE2655681A1 (de) |
| DK (1) | DK529276A (de) |
| ES (1) | ES453947A1 (de) |
| FI (1) | FI763343A (de) |
| FR (1) | FR2334357A1 (de) |
| GB (1) | GB1524589A (de) |
| GR (1) | GR62009B (de) |
| IL (1) | IL51024A (de) |
| NL (1) | NL7613160A (de) |
| NO (1) | NO764025L (de) |
| NZ (1) | NZ182756A (de) |
| OA (1) | OA05506A (de) |
| PH (1) | PH12259A (de) |
| PL (1) | PL103751B1 (de) |
| PT (1) | PT65915B (de) |
| SE (1) | SE430504B (de) |
| ZA (1) | ZA767331B (de) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4105767A (en) * | 1977-03-28 | 1978-08-08 | Merck & Co., Inc. | Imidazo [1,2-a] pyridines substituted with a thienyl, thiazolyl, or thiadiazolyl group |
| US4154835A (en) * | 1977-10-12 | 1979-05-15 | Merck & Co., Inc. | Anthelmintic imidazo [1,2-a] pyridines |
| US4250174A (en) * | 1979-05-02 | 1981-02-10 | Merck & Co., Inc. | 3-Substituted imidazo [1,2-A] pyridines |
| US4221796A (en) * | 1979-09-19 | 1980-09-09 | E. R. Squibb & Sons, Inc. | Substituted imidazolo-pyridines and method |
| ZA81219B (en) * | 1980-01-23 | 1982-01-27 | Schering Corp | Imidazo (1,2-a) pyridines ,process for their preparation and pharmaceutical compositions containing them |
| US4507481A (en) * | 1983-07-29 | 1985-03-26 | Pennwalt Corporation | Pyrrolo[1,2-a]imidazoles and imidazo[1,2-a]pyridines |
| IT1173196B (it) * | 1984-02-02 | 1987-06-18 | Bellon Roger Schoum Rbs Pharma | Composti imidazopiridinici farmacologicamente attivi |
| US5214138A (en) * | 1989-12-20 | 1993-05-25 | Case Western Reserve University | Imidazopyridinium compound and processes for isolating, identifying, and chemically synthesizing same |
| ES2069137T3 (es) * | 1990-07-30 | 1995-05-01 | Takeda Chemical Industries Ltd | Derivados de imidazopiridina y su uso. |
| US6358971B1 (en) | 1998-05-20 | 2002-03-19 | Eli Lilly And Company | Anti-viral compounds |
| CZ289425B6 (cs) * | 1998-05-20 | 2002-01-16 | Eli Lilly And Company | Imidazo[1,2-a] pyridinové sloučeniny, jejich pouľití a farmaceutický přípravek s jejich obsahem |
| DE10117184A1 (de) * | 2001-04-05 | 2002-10-17 | Gruenenthal Gmbh | Substituierte Imidazol[1,2-a]-pyridin-3-yl-amid- und -aminverbindungen |
| EP1737459B1 (de) * | 2004-03-19 | 2009-08-05 | Warner-Lambert Company LLC | Imidazopyridin- und imidazopyrimidin-derivate als antibakterielle mittel |
| CA2576993C (en) * | 2004-08-12 | 2013-09-24 | Amgen Inc. | Bisaryl-sulfonamides |
| CL2008001626A1 (es) * | 2007-06-05 | 2009-06-05 | Takeda Pharmaceuticals Co | Compuestos derivados de heterociclos fusionados, agente farmaceutico que los comprende y su uso en la profilaxis y tratamiento del cancer. |
| US8058274B2 (en) * | 2007-08-17 | 2011-11-15 | Icagen, Inc. | Heterocycles as potassium channel modulators |
| US8431608B2 (en) | 2007-08-17 | 2013-04-30 | Icagen Inc. | Heterocycles as potassium channel modulators |
| WO2009025358A1 (ja) * | 2007-08-23 | 2009-02-26 | Takeda Pharmaceutical Company Limited | 複素環化合物およびその用途 |
| EP2184285B1 (de) * | 2007-08-29 | 2015-11-04 | Takeda Pharmaceutical Company Limited | Heterocyclische verbindung und ihre verwendung |
| EP2444403A1 (de) | 2008-04-18 | 2012-04-25 | Shionogi Co., Ltd. | Heterocyclische Verbindung mit hemmender Wirkung gegenüber PI3K |
| US8445509B2 (en) * | 2008-05-08 | 2013-05-21 | Takeda Pharmaceutical Company Limited | Fused heterocyclic derivatives and use thereof |
| JP5579619B2 (ja) * | 2008-12-01 | 2014-08-27 | 武田薬品工業株式会社 | 複素環化合物およびその用途 |
| JO3101B1 (ar) | 2008-12-02 | 2017-09-20 | Takeda Pharmaceuticals Co | مشتقات بنزوثيازول كعوامل مضادة للسرطان |
| US9567318B2 (en) * | 2009-08-17 | 2017-02-14 | Memorial Sloan-Kettering Cancer Center | Substituted pyrimidine compounds and uses thereof |
| JP6607870B2 (ja) | 2014-05-13 | 2019-11-20 | メモリアル スローン ケタリング キャンサー センター | Ｈｓｐ７０モジュレーターならびにその作製および使用方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3701780A (en) * | 1970-09-18 | 1972-10-31 | Merck & Co Inc | Imidazo(1,2-a)pyridines |
| JPS5124517B1 (de) * | 1971-03-15 | 1976-07-24 |
-
1976
- 1976-08-26 US US05/718,652 patent/US4096264A/en not_active Expired - Lifetime
- 1976-11-22 FI FI763343A patent/FI763343A/fi not_active Application Discontinuation
- 1976-11-24 DK DK529276A patent/DK529276A/da not_active Application Discontinuation
- 1976-11-24 SE SE7613128A patent/SE430504B/xx unknown
- 1976-11-25 NL NL7613160A patent/NL7613160A/xx not_active Application Discontinuation
- 1976-11-25 NO NO764025A patent/NO764025L/no unknown
- 1976-11-29 NZ NZ182756A patent/NZ182756A/xx unknown
- 1976-11-29 IL IL51024A patent/IL51024A/xx unknown
- 1976-11-30 AU AU20102/76A patent/AU505045B2/en not_active Expired
- 1976-12-01 CH CH1513176A patent/CH626362A5/de not_active IP Right Cessation
- 1976-12-01 AR AR265695A patent/AR222960A1/es active
- 1976-12-02 PT PT65915A patent/PT65915B/pt unknown
- 1976-12-03 ES ES453947A patent/ES453947A1/es not_active Expired
- 1976-12-06 AT AT901876A patent/AT361475B/de not_active IP Right Cessation
- 1976-12-07 GR GR52346A patent/GR62009B/el unknown
- 1976-12-07 BE BE173014A patent/BE849123A/xx not_active IP Right Cessation
- 1976-12-07 PH PH19211A patent/PH12259A/en unknown
- 1976-12-07 CA CA267,311A patent/CA1084930A/en not_active Expired
- 1976-12-07 GB GB51010/76A patent/GB1524589A/en not_active Expired
- 1976-12-07 FR FR7636779A patent/FR2334357A1/fr active Granted
- 1976-12-08 PL PL1976194238A patent/PL103751B1/pl unknown
- 1976-12-08 ZA ZA00767331A patent/ZA767331B/xx unknown
- 1976-12-08 DE DE19762655681 patent/DE2655681A1/de not_active Ceased
- 1976-12-09 JP JP51147227A patent/JPS5273896A/ja active Granted
- 1976-12-09 OA OA56008A patent/OA05506A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT65915A (en) | 1977-01-01 |
| PL103751B1 (pl) | 1979-07-31 |
| AU2010276A (en) | 1978-06-08 |
| CA1084930A (en) | 1980-09-02 |
| DK529276A (da) | 1977-06-10 |
| OA05506A (fr) | 1981-04-30 |
| US4096264A (en) | 1978-06-20 |
| IL51024A0 (en) | 1977-01-31 |
| SE430504B (sv) | 1983-11-21 |
| IL51024A (en) | 1981-12-31 |
| JPS6126545B2 (de) | 1986-06-20 |
| JPS5273896A (en) | 1977-06-21 |
| GR62009B (en) | 1979-02-15 |
| AU505045B2 (en) | 1979-11-08 |
| ATA901876A (de) | 1980-08-15 |
| FR2334357A1 (fr) | 1977-07-08 |
| ZA767331B (en) | 1978-07-26 |
| SE7613128L (sv) | 1977-06-10 |
| NO764025L (de) | 1977-06-10 |
| PH12259A (en) | 1978-12-12 |
| AR222960A1 (es) | 1981-07-15 |
| CH626362A5 (de) | 1981-11-13 |
| FR2334357B1 (de) | 1982-10-15 |
| ES453947A1 (es) | 1978-03-01 |
| NZ182756A (en) | 1979-11-01 |
| GB1524589A (en) | 1978-09-13 |
| FI763343A (de) | 1977-06-10 |
| BE849123A (fr) | 1977-06-07 |
| NL7613160A (nl) | 1977-06-13 |
| PT65915B (en) | 1978-11-07 |
| DE2655681A1 (de) | 1977-06-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ELJ | Ceased due to non-payment of the annual fee |