ATA901876A - Verfahren zur herstellung von neuen substi- tuierten imidazo(1,2-a)pyridinverbidnungen und ihren salzen - Google Patents

Verfahren zur herstellung von neuen substi- tuierten imidazo(1,2-a)pyridinverbidnungen und ihren salzen

Info

Publication number
ATA901876A
ATA901876A AT901876A AT901876A ATA901876A AT A901876 A ATA901876 A AT A901876A AT 901876 A AT901876 A AT 901876A AT 901876 A AT901876 A AT 901876A AT A901876 A ATA901876 A AT A901876A
Authority
AT
Austria
Prior art keywords
salts
pyridine compounds
producing new
new substituted
substituted imidazo
Prior art date
Application number
AT901876A
Other languages
English (en)
Other versions
AT361475B (de
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of ATA901876A publication Critical patent/ATA901876A/de
Application granted granted Critical
Publication of AT361475B publication Critical patent/AT361475B/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/42Radicals substituted by singly-bound nitrogen atoms having hetero atoms attached to the substituent nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/53Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/86Hydrazides; Thio or imino analogues thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
AT901876A 1975-12-09 1976-12-06 Verfahren zur herstellung von neuen substi- tuierten imidazo(1,2-a)pyridinverbidnungen und ihren salzen AT361475B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63903475A 1975-12-09 1975-12-09

Publications (2)

Publication Number Publication Date
ATA901876A true ATA901876A (de) 1980-08-15
AT361475B AT361475B (de) 1981-03-10

Family

ID=24562456

Family Applications (1)

Application Number Title Priority Date Filing Date
AT901876A AT361475B (de) 1975-12-09 1976-12-06 Verfahren zur herstellung von neuen substi- tuierten imidazo(1,2-a)pyridinverbidnungen und ihren salzen

Country Status (25)

Country Link
US (1) US4096264A (de)
JP (1) JPS5273896A (de)
AR (1) AR222960A1 (de)
AT (1) AT361475B (de)
AU (1) AU505045B2 (de)
BE (1) BE849123A (de)
CA (1) CA1084930A (de)
CH (1) CH626362A5 (de)
DE (1) DE2655681A1 (de)
DK (1) DK529276A (de)
ES (1) ES453947A1 (de)
FI (1) FI763343A (de)
FR (1) FR2334357A1 (de)
GB (1) GB1524589A (de)
GR (1) GR62009B (de)
IL (1) IL51024A (de)
NL (1) NL7613160A (de)
NO (1) NO764025L (de)
NZ (1) NZ182756A (de)
OA (1) OA05506A (de)
PH (1) PH12259A (de)
PL (1) PL103751B1 (de)
PT (1) PT65915B (de)
SE (1) SE430504B (de)
ZA (1) ZA767331B (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4105767A (en) * 1977-03-28 1978-08-08 Merck & Co., Inc. Imidazo [1,2-a] pyridines substituted with a thienyl, thiazolyl, or thiadiazolyl group
US4154835A (en) * 1977-10-12 1979-05-15 Merck & Co., Inc. Anthelmintic imidazo [1,2-a] pyridines
US4250174A (en) * 1979-05-02 1981-02-10 Merck & Co., Inc. 3-Substituted imidazo [1,2-A] pyridines
US4221796A (en) * 1979-09-19 1980-09-09 E. R. Squibb & Sons, Inc. Substituted imidazolo-pyridines and method
ZA81219B (en) * 1980-01-23 1982-01-27 Schering Corp Imidazo (1,2-a) pyridines ,process for their preparation and pharmaceutical compositions containing them
US4507481A (en) * 1983-07-29 1985-03-26 Pennwalt Corporation Pyrrolo[1,2-a]imidazoles and imidazo[1,2-a]pyridines
IT1173196B (it) * 1984-02-02 1987-06-18 Bellon Roger Schoum Rbs Pharma Composti imidazopiridinici farmacologicamente attivi
US5214138A (en) * 1989-12-20 1993-05-25 Case Western Reserve University Imidazopyridinium compound and processes for isolating, identifying, and chemically synthesizing same
US5244908A (en) * 1990-07-30 1993-09-14 Takeda Chemical Industries, Ltd. Imidazopyridine derivatives and their pharmaceutical use
US6358971B1 (en) 1998-05-20 2002-03-19 Eli Lilly And Company Anti-viral compounds
KR20010025055A (ko) * 1998-05-20 2001-03-26 피터 지. 스트링거 항바이러스 화합물
DE10117184A1 (de) * 2001-04-05 2002-10-17 Gruenenthal Gmbh Substituierte Imidazol[1,2-a]-pyridin-3-yl-amid- und -aminverbindungen
ATE438400T1 (de) * 2004-03-19 2009-08-15 Warner Lambert Co Imidazopyridin- und imidazopyrimidin-derivate als antibakterielle mittel
CA2576993C (en) * 2004-08-12 2013-09-24 Amgen Inc. Bisaryl-sulfonamides
CL2008001626A1 (es) * 2007-06-05 2009-06-05 Takeda Pharmaceuticals Co Compuestos derivados de heterociclos fusionados, agente farmaceutico que los comprende y su uso en la profilaxis y tratamiento del cancer.
JP5463287B2 (ja) * 2007-08-17 2014-04-09 アイカジェン, インコーポレイテッド カリウムチャネル調節物質としての複素環
US8431608B2 (en) 2007-08-17 2013-04-30 Icagen Inc. Heterocycles as potassium channel modulators
EP2181987B9 (de) * 2007-08-23 2014-09-03 Takeda Pharmaceutical Company Limited 2-Carbonylaminobenzothiazole und ihre Verwendung zur Vorbeugung und Behandlung von Krebs
WO2009028629A1 (ja) * 2007-08-29 2009-03-05 Takeda Pharmaceutical Company Limited 複素環化合物およびその用途
EP2277881A4 (de) * 2008-04-18 2011-09-07 Shionogi & Co Heterocyclische verbindung mit inhibierender wirkung auf p13k
WO2009136663A1 (en) * 2008-05-08 2009-11-12 Takeda Pharmaceutical Company Limited Fused heterocyclic derivatives and use thereof
JP5579619B2 (ja) * 2008-12-01 2014-08-27 武田薬品工業株式会社 複素環化合物およびその用途
JO3101B1 (ar) * 2008-12-02 2017-09-20 Takeda Pharmaceuticals Co مشتقات بنزوثيازول كعوامل مضادة للسرطان
BR112012003637A2 (pt) 2009-08-17 2017-04-25 Memorial Sloan Kettering Cancer Center "compostos de ligação de proteína de choque térmico, composições, e métodos para preparar e usar os mesmos"
CA2948621A1 (en) 2014-05-13 2015-11-19 Memorial Sloan Kettering Cancer Center Hsp70 modulators and methods for making and using the same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3701780A (en) * 1970-09-18 1972-10-31 Merck & Co Inc Imidazo(1,2-a)pyridines
JPS5124517B1 (de) * 1971-03-15 1976-07-24

Also Published As

Publication number Publication date
PT65915A (en) 1977-01-01
JPS6126545B2 (de) 1986-06-20
AU2010276A (en) 1978-06-08
NO764025L (de) 1977-06-10
PH12259A (en) 1978-12-12
AU505045B2 (en) 1979-11-08
PT65915B (en) 1978-11-07
IL51024A0 (en) 1977-01-31
PL103751B1 (pl) 1979-07-31
US4096264A (en) 1978-06-20
FI763343A (de) 1977-06-10
SE430504B (sv) 1983-11-21
NZ182756A (en) 1979-11-01
BE849123A (fr) 1977-06-07
JPS5273896A (en) 1977-06-21
IL51024A (en) 1981-12-31
DK529276A (da) 1977-06-10
ZA767331B (en) 1978-07-26
NL7613160A (nl) 1977-06-13
GB1524589A (en) 1978-09-13
CH626362A5 (de) 1981-11-13
DE2655681A1 (de) 1977-06-16
AR222960A1 (es) 1981-07-15
AT361475B (de) 1981-03-10
GR62009B (en) 1979-02-15
ES453947A1 (es) 1978-03-01
SE7613128L (sv) 1977-06-10
FR2334357B1 (de) 1982-10-15
FR2334357A1 (fr) 1977-07-08
OA05506A (fr) 1981-04-30
CA1084930A (en) 1980-09-02

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